Merkel cell polyomavirus small t antigen induces cancer and embryonic merkel cell proliferation in a transgenic mouse model

PLoS ONE

Volumn 10, Issue 11, 2015, Pages

  Shuda, Masahiro ^a   Guastafierro, Anna ^a,d   Geng, Xuehui ^b   Shuda, Yoko ^a   Ostrowski, Stephen M ^c,e   Lukianov, Stefan ^a   Jenkins, Frank J ^b   Honda, Kord ^c   Maricich, Stephen M ^b   Moore, Patrick S ^a   Chang, Yuan ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MERKEL CELL POLYOMAVIRUS SMALL T ANTIGEN; PROTEIN P53; UNCLASSIFIED DRUG; VIRUS SMALL T ANTIGEN; VIRUS T ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ARTICLE; CARCINOGENESIS; CELL ANCHORAGE; CELL COUNT; CELL GROWTH; CELL LINEAGE; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; EMBRYO; EPIDERMIS HYPERPLASIA; FEMALE; FIBROBLAST; HYPERKERATOSIS; MALE; MERKEL CELL; MOUSE; NONHUMAN; SEQUENCE HOMOLOGY; TRANSGENIC MOUSE; ANAPLASTIC CARCINOMA; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; DEFICIENCY; DISEASE MODEL; GENETICS; HUMAN; IMMUNOLOGY; LIVER; MAMMALIAN EMBRYO; MERKEL CELL POLYOMAVIRUS; MERKEL CELL TUMOR; PATHOLOGY; PHYSIOLOGY; PREGNANCY; SKIN TUMOR; SPLEEN; TUMOR CELL LINE; VIROLOGY; VIRUS CELL TRANSFORMATION;

ANAPLASIA; ANIMALS; ANTIGENS, VIRAL, TUMOR; CARCINOMA, MERKEL CELL; CELL COUNT; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, VIRAL; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; FEMALE; HUMANS; LIVER; MALE; MERKEL CELL POLYOMAVIRUS; MERKEL CELLS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PREGNANCY; SKIN NEOPLASMS; SPLEEN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84953320759     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0142329     Document Type: Article

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