-
1
-
-
60549115605
-
Post-transcriptional processing generates a diversity of 5'-modified long and short RNAs
-
Affymetrix/Cold Spring Harbor Laboratory ENCODE Transcriptome Project
-
Affymetrix/Cold Spring Harbor Laboratory ENCODE Transcriptome Project (Fejes-Toth K, Sotirova V, Sachidanandam R, Assaf G, Hannon GJ, Kapranov P, Foissac S, Willingham AT, Duttagupta R, Dumais E, Gingeras TR). 2009. Post-transcriptional processing generates a diversity of 5'-modified long and short RNAs. Nature 457: 1028-1032.
-
(2009)
Nature
, vol.457
, pp. 1028-1032
-
-
Fejes-Toth, K.1
Sotirova, V.2
Sachidanandam, R.3
Assaf, G.4
Hannon, G.J.5
Kapranov, P.6
Foissac, S.7
Willingham, A.T.8
Duttagupta, R.9
Dumais, E.10
Gingeras, T.R.11
-
2
-
-
0035937417
-
Modulation of a transcription factor counteracts heterochromatic gene silencing in Drosophila
-
Ahmad K, Henikoff S. 2001. Modulation of a transcription factor counteracts heterochromatic gene silencing in Drosophila. Cell 104: 839- 847.
-
(2001)
Cell
, vol.104
, pp. 839-847
-
-
Ahmad, K.1
Henikoff, S.2
-
4
-
-
84880510553
-
Promoter directionality is controlled by U1 snRNP and polyadenylation signals
-
AlmadaAE, Wu X, Kriz AJ, Burge CB, Sharp PA. 2013. Promoter directionality is controlled by U1 snRNP and polyadenylation signals. Nature 499: 360-363.
-
(2013)
Nature
, vol.499
, pp. 360-363
-
-
Almada, A.E.1
Wu, X.2
Kriz, A.J.3
Burge, C.B.4
Sharp, P.A.5
-
5
-
-
84891665594
-
Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread
-
Al-Sady B, Madhani HD, Narlikar GJ. 2013. Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread. Mol Cell 51: 80-91.
-
(2013)
Mol Cell
, vol.51
, pp. 80-91
-
-
Al-Sady, B.1
Madhani, H.D.2
Narlikar, G.J.3
-
6
-
-
84865102747
-
A Swiss army knife of immunity
-
Brouns SJ. 2012. A Swiss army knife of immunity. Science 337: 808-809.
-
(2012)
Science
, vol.337
, pp. 808-809
-
-
Brouns, S.J.1
-
7
-
-
0030723797
-
A silencer is required for maintenance of transcriptional repression throughout Drosophila development
-
Busturia A, Wightman CD, Sakonju S. 1997. A silencer is required for maintenance of transcriptional repression throughout Drosophila development. Development 124: 4343-4350.
-
(1997)
Development
, vol.124
, pp. 4343-4350
-
-
Busturia, A.1
Wightman, C.D.2
Sakonju, S.3
-
8
-
-
79959811626
-
Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output
-
Celona B, Weiner A, Di Felice F, Mancuso FM, Cesarini E, Rossi RL, Gregory L, Baban D, Rossetti G, Grianti P, et al. 2011. Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output. PLoS Biol 9: e1001086.
-
(2011)
PLoS Biol
, vol.9
-
-
Celona, B.1
Weiner, A.2
Di Felice, F.3
Mancuso, F.M.4
Cesarini, E.5
Rossi, R.L.6
Gregory, L.7
Baban, D.8
Rossetti, G.9
Grianti, P.10
-
9
-
-
83555164884
-
Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila
-
CernilogarFM, Onorati MC, Kothe GO, Burroughs AM, Parsi KM, Breiling A, Sardo FL, Saxena A, Miyoshi K, Siomi H, et al. 2011. Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila. Nature 480: 391-395.
-
(2011)
Nature
, vol.480
, pp. 391-395
-
-
Cernilogar, F.M.1
Onorati, M.C.2
Kothe, G.O.3
Burroughs, A.M.4
Parsi, K.M.5
Breiling, A.6
Sardo, F.L.7
Saxena, A.8
Miyoshi, K.9
Siomi, H.10
-
10
-
-
84877299145
-
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
-
Chan K-M, Fang D, Gan H, Hashizume R, Yu C, Schroeder M, Gupta N, Mueller S, James CD, Jenkins R, et al. 2013. The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression. Genes Dev 27: 985-990.
-
(2013)
Genes Dev
, vol.27
, pp. 985-990
-
-
Chan, K.-M.1
Fang, D.2
Gan, H.3
Hashizume, R.4
Yu, C.5
Schroeder, M.6
Gupta, N.7
Mueller, S.8
James, C.D.9
Jenkins, R.10
-
11
-
-
79959348134
-
The polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryo
-
Chopra VS, Hendrix DA, Core LJ, Tsui C, Lis JT, Levine M. 2011. The polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryo. Mol Cell 42: 837-844.
-
(2011)
Mol Cell
, vol.42
, pp. 837-844
-
-
Chopra, V.S.1
Hendrix, D.A.2
Core, L.J.3
Tsui, C.4
Lis, J.T.5
Levine, M.6
-
14
-
-
77952908743
-
A large fraction of extragenic RNA Pol II transcription sites overlap enhancers
-
DeSanta F, Barozzi I, Mietton F, Ghisletti S, Polletti S, Tusi BK,Muller H, Ragoussis J, Wei C-L, Natoli G. 2010. A large fraction of extragenic RNA Pol II transcription sites overlap enhancers. PLoS Biol 8: e1000384.
-
(2010)
PLoS Biol
, vol.8
-
-
DeSanta, F.1
Barozzi, I.2
Mietton, F.3
Ghisletti, S.4
Polletti, S.5
Tusi, B.K.6
Muller, H.7
Ragoussis, J.8
Wei, C.-L.9
Natoli, G.10
-
15
-
-
10044244766
-
Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila
-
Ebert A, Schotta G, Lein S, Kubicek S, Krauss V, Jenuwein T, Reuter G. 2004. Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev 18: 2973-2983.
-
(2004)
Genes Dev
, vol.18
, pp. 2973-2983
-
-
Ebert, A.1
Schotta, G.2
Lein, S.3
Kubicek, S.4
Krauss, V.5
Jenuwein, T.6
Reuter, G.7
-
16
-
-
84878988149
-
KDM2B links the Polycomb repressive complex 1 (PRC1) to recognition of CpG islands
-
Farcas AM, Blackledge NP, Sudbery I, Long HK,McGouran JF, Rose NR, Lee S, Sims D, Cerase A, Sheahan TW, et al. 2012. KDM2B links the Polycomb repressive complex 1 (PRC1) to recognition of CpG islands. eLife 1: e00205.
-
(2012)
eLife
, vol.1
-
-
Farcas, A.M.1
Blackledge, N.P.2
Sudbery, I.3
Long, H.K.4
McGouran, J.F.5
Rose, N.R.6
Lee, S.7
Sims, D.8
Cerase, A.9
Sheahan, T.W.10
-
17
-
-
84892366110
-
Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity
-
FerrariKJ, Scelfo A, Jammula S, Cuomo A, Barozzi I, Stützer A, FischleW, Bonaldi T, Pasini D. 2014. Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity. Mol Cell 53: 49-62.
-
(2014)
Mol Cell
, vol.53
, pp. 49-62
-
-
Ferrari, K.J.1
Scelfo, A.2
Jammula, S.3
Cuomo, A.4
Barozzi, I.5
Stützer, A.6
Fischle, W.7
Bonaldi, T.8
Pasini, D.9
-
18
-
-
84879888213
-
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
-
Fradet-Turcotte A, Canny MD, Escribano-Diaz C, Orthwein A, Leung CCY, Huang H, Landry M-C, Kitevski-LeBlanc J, Noordermeer SM, Sicheri F, et al. 2013. 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark. Nature 499: 50-54.
-
(2013)
Nature
, vol.499
, pp. 50-54
-
-
Fradet-Turcotte, A.1
Canny, M.D.2
Escribano-Diaz, C.3
Orthwein, A.4
Leung, C.C.Y.5
Huang, H.6
Landry, M.-C.7
Kitevski-LeBlanc, J.8
Noordermeer, S.M.9
Sicheri, F.10
-
19
-
-
84864647205
-
Site-specific DICER and DROSHA RNA products control the DNA-damage response
-
Francia S, Michelini F, Saxena A, Tang D, de Hoon M, Anelli V, Mione M, Carninci P, d'Adda di Fagagna F. 2012. Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature 488: 231-235.
-
(2012)
Nature
, vol.488
, pp. 231-235
-
-
Francia, S.1
Michelini, F.2
Saxena, A.3
Tang, D.4
de Hoon, M.5
Anelli, V.6
Mione, M.7
Carninci, P.8
d'Adda di Fagagna, F.9
-
20
-
-
84876838711
-
The hierarchy of the 3D genome
-
Gibcus JH, Dekker J. 2013. The hierarchy of the 3D genome. Mol Cell 49: 773-782.
-
(2013)
Mol Cell
, vol.49
, pp. 773-782
-
-
Gibcus, J.H.1
Dekker, J.2
-
21
-
-
84864059329
-
In vivo effects of histone H3 depletion on nucleosome occupancy and position in Saccharomyces cerevisiae
-
Gossett AJ, Lieb JD. 2012. In vivo effects of histone H3 depletion on nucleosome occupancy and position in Saccharomyces cerevisiae. PLoS Genet 8: e1002771.
-
(2012)
PLoS Genet
, vol.8
-
-
Gossett, A.J.1
Lieb, J.D.2
-
22
-
-
33644770293
-
RNAi components are required for nuclear clustering of Polycomb group response elements
-
GrimaudC, Bantignies F, Pal-Bhadra M, Ghana P, Bhadra U, Cavalli G. 2006. RNAi components are required for nuclear clustering of Polycomb group response elements. Cell 124: 957-971.
-
(2006)
Cell
, vol.124
, pp. 957-971
-
-
Grimaud, C.1
Bantignies, F.2
Pal-Bhadra, M.3
Ghana, P.4
Bhadra, U.5
Cavalli, G.6
-
23
-
-
0024261583
-
Nucleosome loss activates yeast downstream promoters in vivo
-
Han M, Grunstein M. 1988. Nucleosome loss activates yeast downstream promoters in vivo. Cell 55: 1137-1145.
-
(1988)
Cell
, vol.55
, pp. 1137-1145
-
-
Han, M.1
Grunstein, M.2
-
24
-
-
84862662420
-
Dynamics and memory of heterochromatin in living cells
-
Hathaway NA, Bell O, Hodges C, Miller EL, Neel DS, Crabtree GR. 2012. Dynamics and memory of heterochromatin in living cells. Cell 149: 1447-1460.
-
(2012)
Cell
, vol.149
, pp. 1447-1460
-
-
Hathaway, N.A.1
Bell, O.2
Hodges, C.3
Miller, E.L.4
Neel, D.S.5
Crabtree, G.R.6
-
25
-
-
33847334699
-
Distinctive and predictive chromain signatures of transcriptional promoters and enhancers in the human genome
-
Heintzman ND, Stuart RK, Hon G, Fu YT, Ching CW, Hawkins RD, Barrera LO, Van Calcar S, Qu C, Ching KA, et al. 2007. Distinctive and predictive chromain signatures of transcriptional promoters and enhancers in the human genome. Nat Genet 39: 311-318.
-
(2007)
Nat Genet
, vol.39
, pp. 311-318
-
-
Heintzman, N.D.1
Stuart, R.K.2
Hon, G.3
Fu, Y.T.4
Ching, C.W.5
Hawkins, R.D.6
Barrera, L.O.7
Van Calcar, S.8
Qu, C.9
Ching, K.A.10
-
26
-
-
80052805267
-
Histone modification: Cause or cog
-
Henikoff S, Shilatifard A. 2011. Histone modification: Cause or cog? Trends Genet 27: 389-396.
-
(2011)
Trends Genet
, vol.27
, pp. 389-396
-
-
Henikoff, S.1
Shilatifard, A.2
-
27
-
-
84870490787
-
Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4
-
Herz H-M, Mohan M, Garruss AS, Liang K, Takahashi Y-H, Mickey K, Voets O, Verrijzer CP, Shilatifard A. 2012. Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4. Genes Dev 26: 2604-2620.
-
(2012)
Genes Dev
, vol.26
, pp. 2604-2620
-
-
Herz, H.-M.1
Mohan, M.2
Garruss, A.S.3
Liang, K.4
Takahashi, Y.-H.5
Mickey, K.6
Voets, O.7
Verrijzer, C.P.8
Shilatifard, A.9
-
28
-
-
84859831338
-
A complex Polycomb issue: The two faces of EZH2 in cancer
-
Hock H. 2012. A complex Polycomb issue: The two faces of EZH2 in cancer. Genes Dev 26: 751-755.
-
(2012)
Genes Dev
, vol.26
, pp. 751-755
-
-
Hock, H.1
-
29
-
-
34748898280
-
Methylation- acetylation interplay activates p53 in response to DNA damage
-
Ivanov GS, Ivanova T, Kurash J, Ivanov A, Chuikov S, Gizatullin F, Herrera- Medina EM, Rauscher F III, Reinberg D, Barlev NA. 2007.Methylation- acetylation interplay activates p53 in response to DNA damage. Mol Cell Biol 27: 6756-6769.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6756-6769
-
-
Ivanov, G.S.1
Ivanova, T.2
Kurash, J.3
Ivanov, A.4
Chuikov, S.5
Gizatullin, F.6
Herrera- Medina, E.M.7
Rauscher F, I.I.I.8
Reinberg, D.9
Barlev, N.A.10
-
30
-
-
68149150830
-
H3.3/ H2A.Z double variant-containing nucleosomes mark 'nucleosomefree regions' of active promoters and other regulatory regions
-
Jin C, Zang C,Wei G, Cui K, PengW, Zhao K, Felsenfeld G. 2009. H3.3/ H2A.Z double variant-containing nucleosomes mark 'nucleosomefree regions' of active promoters and other regulatory regions. Nat Genet 41: 941-945.
-
(2009)
Nat Genet
, vol.41
, pp. 941-945
-
-
Jin, C.1
Zang, C.2
Wei, G.3
Cui, K.4
Peng, W.5
Zhao, K.6
Felsenfeld, G.7
-
31
-
-
77951855269
-
Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36
-
Jung HR, Pasini D, Helin K, Jensen ON. 2010. Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36. Mol Cell Proteomics 9: 838-850.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 838-850
-
-
Jung, H.R.1
Pasini, D.2
Helin, K.3
Jensen, O.N.4
-
32
-
-
84887460647
-
PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells
-
Kaneko S, Son J, Shen SS, ReinbergD, Bonasio R. 2013. PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells. Nat Struct Mol Biol 20: 1258-1264.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 1258-1264
-
-
Kaneko, S.1
Son, J.2
Shen, S.S.3
Reinberg, D.4
Bonasio, R.5
-
33
-
-
77952367798
-
Widespread transcription at neuronal activity-regulated enhancers
-
Kim T-K, Hemberg M, Gray JM, Costa AM, Bear DM,Wu J, HarminDA, Laptewicz M, Barbara-Haley K, Kuersten S, et al. 2010. Widespread transcription at neuronal activity-regulated enhancers. Nature 465: 182-187.
-
(2010)
Nature
, vol.465
, pp. 182-187
-
-
Kim, T.-K.1
Hemberg, M.2
Gray, J.M.3
Costa, A.M.4
Bear, D.M.5
Wu, J.6
Harmin, D.A.7
Laptewicz, M.8
Barbara-Haley, K.9
Kuersten, S.10
-
34
-
-
84884626274
-
Chromatin sampling-An emerging perspective on targeting polycomb repressor proteins
-
Klose RJ, Cooper S, Farcas AM, Blackledge NP, Brockdorff N. 2013. Chromatin sampling-An emerging perspective on targeting polycomb repressor proteins. PLoS Genet 9: e1003717.
-
(2013)
PLoS Genet
, vol.9
-
-
Klose, R.J.1
Cooper, S.2
Farcas, A.M.3
Blackledge, N.P.4
Brockdorff, N.5
-
35
-
-
84886860116
-
TETenzymes, TDG and the dynamics of DNA demethylation
-
KohliRM, Zhang Y. 2013. TETenzymes, TDG and the dynamics of DNA demethylation. Nature 502: 472-479.
-
(2013)
Nature
, vol.502
, pp. 472-479
-
-
Kohli, R.M.1
Zhang, Y.2
-
36
-
-
0030922630
-
Mammalian homologues of the Polycombgroup gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres
-
Laible G,Wolf A, Dorn R, Reuter G, Nislow C, Lebersorger A, Popkin D, Pillus L, Jenuwein T. 1997. Mammalian homologues of the Polycombgroup gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres. EMBO J 16: 3219- 3232.
-
(1997)
EMBO J
, vol.16
, pp. 3219-3232
-
-
Laible, G.1
Wolf, A.2
Dorn, R.3
Reuter, G.4
Nislow, C.5
Lebersorger, A.6
Popkin, D.7
Pillus, L.8
Jenuwein, T.9
-
37
-
-
84880231234
-
Epigenomic strategies at the interface of genetic and environmental risk factors for autism
-
LaSalle JM. 2013. Epigenomic strategies at the interface of genetic and environmental risk factors for autism. J Hum Genet 58: 396-401.
-
(2013)
J Hum Genet
, vol.58
, pp. 396-401
-
-
LaSalle, J.M.1
-
38
-
-
84870308969
-
EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase vomplex
-
Lee JM, Lee JS, Kim H, Kim K, Park H, Kim J-Y, Lee SH, Kim IS, Kim J, Lee M, et al. 2012. EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase vomplex. Mol Cell 48: 572-586.
-
(2012)
Mol Cell
, vol.48
, pp. 572-586
-
-
Lee, J.M.1
Lee, J.S.2
Kim, H.3
Kim, K.4
Park, H.5
Kim, J.-Y.6
Lee, S.H.7
Kim, I.S.8
Kim, J.9
Lee, M.10
-
39
-
-
33746472891
-
RNA interference machinery influences the nuclear organization of a chromatin insulator
-
Lei EP, Corces VG. 2006. RNA interference machinery influences the nuclear organization of a chromatin insulator.Nat Genet 38: 936-941.
-
(2006)
Nat Genet
, vol.38
, pp. 936-941
-
-
Lei, E.P.1
Corces, V.G.2
-
40
-
-
0029739422
-
All four core histone N-termini contain sequences required for the repression of basal transcription in yeast
-
Lenfant F, Mann RK, Thomsen B, Ling X, Grunstein M. 1996. All four core histone N-termini contain sequences required for the repression of basal transcription in yeast. EMBO J 15: 3974-3985.
-
(1996)
EMBO J
, vol.15
, pp. 3974-3985
-
-
Lenfant, F.1
Mann, R.K.2
Thomsen, B.3
Ling, X.4
Grunstein, M.5
-
41
-
-
84877785024
-
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
-
Lewis PW, Müller MM, Koletsky MS, Cordero F, Lin S, Banaszynski LA, Garcia BA, Muir TW, Becher OJ, Allis CD. 2013. Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science 340: 857-861.
-
(2013)
Science
, vol.340
, pp. 857-861
-
-
Lewis, P.W.1
Müller, M.M.2
Koletsky, M.S.3
Cordero, F.4
Lin, S.5
Banaszynski, L.A.6
Garcia, B.A.7
Muir, T.W.8
Becher, O.J.9
Allis, C.D.10
-
42
-
-
34249874030
-
Infrequently transcribed long genes depend on the Set2/Rpd3S pathway for accurate transcription
-
Li B, Gogol M, Carey M, Pattenden SG, Seidel C, Workman JL. 2007. Infrequently transcribed long genes depend on the Set2/Rpd3S pathway for accurate transcription. Genes Dev 21: 1422-1430.
-
(2007)
Genes Dev
, vol.21
, pp. 1422-1430
-
-
Li, B.1
Gogol, M.2
Carey, M.3
Pattenden, S.G.4
Seidel, C.5
Workman, J.L.6
-
43
-
-
77950342430
-
Highly compacted chromatin formed in vitro reflects the dynamics of transcription activation in vivo
-
Li G, Margueron R,Hu G, StokesD,Wang Y-H, ReinbergD. 2010. Highly compacted chromatin formed in vitro reflects the dynamics of transcription activation in vivo. Mol Cell 38: 41-53.
-
(2010)
Mol Cell
, vol.38
, pp. 41-53
-
-
Li, G.1
Margueron, R.2
Hu, G.3
Stokes, D.4
Wang, Y.-H.5
Reinberg, D.6
-
44
-
-
59249092289
-
The CTCF insulator protein is posttranslationally modified bySUMO
-
MacPherson MJ, Beatty LG, Zhou W, Du M, Sadowski PD. 2009. The CTCF insulator protein is posttranslationally modified bySUMO. Mol Cell Biol 29: 714-725.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 714-725
-
-
MacPherson, M.J.1
Beatty, L.G.2
Zhou, W.3
Du, M.4
Sadowski, P.D.5
-
45
-
-
70349952171
-
Role of the Polycomb protein EED in the propagation of repressive histone marks
-
Margueron R, Justin N, Ohno K, Sharpe ML, Son J, Drury WJ III, Voigt P, Martin SR, Taylor WR, De Marco V, et al. 2009. Role of the Polycomb protein EED in the propagation of repressive histone marks. Nature 461: 762-767.
-
(2009)
Nature
, vol.461
, pp. 762-767
-
-
Margueron, R.1
Justin, N.2
Ohno, K.3
Sharpe, M.L.4
Son, J.5
Drury, W.J.I.I.I.6
Voigt, P.7
Martin, S.R.8
Taylor, W.R.9
De Marco, V.10
-
46
-
-
84878979335
-
Biology: The big challenges of big data
-
Marx V. 2013. Biology: The big challenges of big data. Nature 498: 255- 260.
-
(2013)
Nature
, vol.498
, pp. 255-260
-
-
Marx, V.1
-
47
-
-
84870573126
-
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
-
McCabeMT, Ott HM, Ganji G, Korenchuk S, Thompson C,Van Aller GS, Liu Y, Graves AP, Della Pietra A III, Diaz E, et al. 2012. EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations. Nature 492: 108-112.
-
(2012)
Nature
, vol.492
, pp. 108-112
-
-
McCabe, M.T.1
Ott, H.M.2
Ganji, G.3
Korenchuk, S.4
Thompson, C.5
Van Aller, G.S.6
Liu, Y.7
Graves, A.P.8
Della Pietra A, I.I.I.9
Diaz, E.10
-
48
-
-
60749105468
-
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
-
McGowan PO, Sasaki A, D'Alessio AC, Dymov S, Labonte B, Szyf M, Turecki G, Meaney MJ. 2009. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 12: 342-348.
-
(2009)
Nat Neurosci
, vol.12
, pp. 342-348
-
-
McGowan, P.O.1
Sasaki, A.2
D'Alessio, A.C.3
Dymov, S.4
Labonte, B.5
Szyf, M.6
Turecki, G.7
Meaney, M.J.8
-
49
-
-
33947098453
-
Histone replacement marks the boundaries of cis-regulatory domains
-
Mito Y, Henikoff JG, Henikoff S. 2007. Histone replacement marks the boundaries of cis-regulatory domains. Science 315: 1408-1411.
-
(2007)
Science
, vol.315
, pp. 1408-1411
-
-
Mito, Y.1
Henikoff, J.G.2
Henikoff, S.3
-
50
-
-
0021084648
-
Histone gene multiplicity and position effect variegation in Drosophila melanogaster
-
Moore GD, Sinclair DA, Grigliatti TA. 1983. Histone gene multiplicity and position effect variegation in Drosophila melanogaster. Genetics 105: 327-344.
-
(1983)
Genetics
, vol.105
, pp. 327-344
-
-
Moore, G.D.1
Sinclair, D.A.2
Grigliatti, T.A.3
-
51
-
-
84860388943
-
RNAi-independent role for Argonaute2 in CTCF/CP190 chromatin insulator function
-
Moshkovich N, Nisha P, Boyle PJ, Thompson BA, Dale RK, Lei EP. 2011. RNAi-independent role for Argonaute2 in CTCF/CP190 chromatin insulator function. Genes Dev 25: 1686-1701.
-
(2011)
Genes Dev
, vol.25
, pp. 1686-1701
-
-
Moshkovich, N.1
Nisha, P.2
Boyle, P.J.3
Thompson, B.A.4
Dale, R.K.5
Lei, E.P.6
-
52
-
-
84881474625
-
Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality
-
Ntini E, Järvelin AI, Bornholdt J, Chen Y, Boyd M, Jørgensen M, Andersson R, Hoof I, Schein A, Andersen PR, et al. 2013. Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality. Nat Struct Mol Biol 20: 923-928.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 923-928
-
-
Ntini, E.1
Järvelin, A.I.2
Bornholdt, J.3
Chen, Y.4
Boyd, M.5
Jørgensen, M.6
Andersson, R.7
Hoof, I.8
Schein, A.9
Andersen, P.R.10
-
53
-
-
84884220048
-
Long noncoding RNAs usher in a newera in the biology of enhancers
-
ØromUA, Shiekhattar R. 2013. Long noncoding RNAs usher in a newera in the biology of enhancers. Cell 154: 1190-1193.
-
(2013)
Cell
, vol.154
, pp. 1190-1193
-
-
Ørom, U.A.1
Shiekhattar, R.2
-
54
-
-
9144268924
-
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin
-
Peters AH, Kubicek S, Mechtler K, O'Sullivan RJ, Derijck AA, Perez- Burgos L, Kohlmaier A, Opravil S, Tachibana M, Shinkai Y, et al. 2003. Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. Mol Cell 12: 1577-1589.
-
(2003)
Mol Cell
, vol.12
, pp. 1577-1589
-
-
Peters, A.H.1
Kubicek, S.2
Mechtler, K.3
O'Sullivan, R.J.4
Derijck, A.A.5
Perez- Burgos, L.6
Kohlmaier, A.7
Opravil, S.8
Tachibana, M.9
Shinkai, Y.10
-
55
-
-
79955494277
-
Histone methylation by PRC2 is inhibited by active chromatin marks
-
Schmitges FW, Prusty AB, Faty M, Stützer A, Lingaraju GM, Aiwazian J, Sack R, HessD, Li L, Zhou S, et al. 2011. Histone methylation by PRC2 is inhibited by active chromatin marks. Mol Cell 42: 330-341.
-
(2011)
Mol Cell
, vol.42
, pp. 330-341
-
-
Schmitges, F.W.1
Prusty, A.B.2
Faty, M.3
Stützer, A.4
Lingaraju, G.M.5
Aiwazian, J.6
Sack, R.7
Hess, D.8
Li, L.9
Zhou, S.10
-
56
-
-
57849140661
-
Divergent transcription from active promoters
-
Seila AC, Calabrese JM, Levine SS, Yeo GW, Rahl PB, Flynn RA, Young RA, Sharp PA. 2008. Divergent transcription from active promoters. Science 322: 1849-1851.
-
(2008)
Science
, vol.322
, pp. 1849-1851
-
-
Seila, A.C.1
Calabrese, J.M.2
Levine, S.S.3
Yeo, G.W.4
Rahl, P.B.5
Flynn, R.A.6
Young, R.A.7
Sharp, P.A.8
-
57
-
-
84859295400
-
A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia
-
Simon C, Chagraoui J, Krosl J, Gendron P, Wilhelm B, Lemieux SB, Boucher GV, Chagnon P, Drouin S, Lambert RL, et al. 2012. A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia. Genes Dev 26: 651-656.
-
(2012)
Genes Dev
, vol.26
, pp. 651-656
-
-
Simon, C.1
Chagraoui, J.2
Krosl, J.3
Gendron, P.4
Wilhelm, B.5
Lemieux, S.B.6
Boucher, G.V.7
Chagnon, P.8
Drouin, S.9
Lambert, R.L.10
-
58
-
-
0020446743
-
Early role of the esc+ gene product in the determination of segments in Drosophila
-
Struhl G, Brower D. 1982. Early role of the esc+ gene product in the determination of segments in Drosophila. Cell 31: 285-292.
-
(1982)
Cell
, vol.31
, pp. 285-292
-
-
Struhl, G.1
Brower, D.2
-
59
-
-
21044451441
-
Polycomb group protein Ezh2 controls actin polymerization and cell signaling
-
Su I-H, DobeneckerM-W, Dickinson E, Oser M, Basavaraj A, Marqueron R, Viale A, Reinberg D, Wülfing C, Tarakhovsky A. 2005. Polycomb group protein Ezh2 controls actin polymerization and cell signaling. Cell 121: 425-436.
-
(2005)
Cell
, vol.121
, pp. 425-436
-
-
Su, I.-H.1
Dobenecker, M.-W.2
Dickinson, E.3
Oser, M.4
Basavaraj, A.5
Marqueron, R.6
Viale, A.7
Reinberg, D.8
Wülfing, C.9
Tarakhovsky, A.10
-
60
-
-
67349157682
-
Tiny RNAs associated with transcription start sites in animals
-
Taft RJ, Glazov EA, Cloonan N, Simons C, Stephen S, Faulkner GJ, Lassmann T, Forrest ARR, Grimmond SM, Schroder K, et al. 2009. Tiny RNAs associated with transcription start sites in animals. Nat Genet 41: 572-578.
-
(2009)
Nat Genet
, vol.41
, pp. 572-578
-
-
Taft, R.J.1
Glazov, E.A.2
Cloonan, N.3
Simons, C.4
Stephen, S.5
Faulkner, G.J.6
Lassmann, T.7
Forrest, A.R.R.8
Grimmond, S.M.9
Schroder, K.10
-
61
-
-
84877584684
-
Global histone modification of H3K27 correlates with the outcomes in patients with metachronous liver metastasis of colorectal cancer
-
Tamagawa H, Oshima T, Numata M, Yamamoto N, Shiozawa M, Morinaga S, Nakamura Y, Yoshihara M, Sakuma Y, Kameda Y, et al. 2013. Global histone modification of H3K27 correlates with the outcomes in patients with metachronous liver metastasis of colorectal cancer. Eur J Surg Oncol 39: 655-661.
-
(2013)
Eur J Surg Oncol
, vol.39
, pp. 655-661
-
-
Tamagawa, H.1
Oshima, T.2
Numata, M.3
Yamamoto, N.4
Shiozawa, M.5
Morinaga, S.6
Nakamura, Y.7
Yoshihara, M.8
Sakuma, Y.9
Kameda, Y.10
-
62
-
-
84864012602
-
Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27
-
Tie F, Banerjee R, Conrad PA, Scacheri PC, Harte PJ. 2012. Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27. Mol Cell Biol 32: 2323-2334.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2323-2334
-
-
Tie, F.1
Banerjee, R.2
Conrad, P.A.3
Scacheri, P.C.4
Harte, P.J.5
-
63
-
-
60149091656
-
ChIP-seq accurately predicts tissue-specific activity of enhancers
-
Visel A, Blow MJ, Li Z, Zhang T, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M,Wright C, Chen F, et al. 2009. ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457: 854-858.
-
(2009)
Nature
, vol.457
, pp. 854-858
-
-
Visel, A.1
Blow, M.J.2
Li, Z.3
Zhang, T.4
Akiyama, J.A.5
Holt, A.6
Plajzer-Frick, I.7
Shoukry, M.8
Wright, C.9
Chen, F.10
-
64
-
-
0034707037
-
Global histone acetylation and deacetylation in yeast
-
Vogelauer M, Wu J, Suka N, Grunstein M. 2000. Global histone acetylation and deacetylation in yeast. Nature 408: 495-498.
-
(2000)
Nature
, vol.408
, pp. 495-498
-
-
Vogelauer, M.1
Wu, J.2
Suka, N.3
Grunstein, M.4
-
65
-
-
84867009687
-
Asymmetrically modified nucleosomes
-
Voigt P, LeRoy G, Drury WJ III, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D. 2012. Asymmetrically modified nucleosomes. Cell 151: 181-193.
-
(2012)
Cell
, vol.151
, pp. 181-193
-
-
Voigt, P.1
LeRoy, G.2
Drury, W.J.I.I.I.3
Zee, B.M.4
Son, J.5
Beck, D.B.6
Young, N.L.7
Garcia, B.A.8
Reinberg, D.9
-
66
-
-
0016376109
-
Nonspecific DNA binding of genome regulating proteins as a biological control mechanism: The lac operon: Equilibrium aspects
-
von Hippel P, Revzin A, Gross C,Wang A. 1974. Nonspecific DNA binding of genome regulating proteins as a biological control mechanism
-
(1974)
Proc Natl Acad Sci
, vol.71
, pp. 4808-4812
-
-
von Hippel, P.1
Revzin, A.2
Gross, C.3
Wang, A.4
-
67
-
-
3342989681
-
Epigenetic programming by maternal behavior
-
Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, Seckl JR, Dymov S, Szyf M, Meaney MJ. 2004. Epigenetic programming by maternal behavior. Nat Neurosci 7: 847-854.
-
(2004)
Nat Neurosci
, vol.7
, pp. 847-854
-
-
Weaver, I.C.1
Cervoni, N.2
Champagne, F.A.3
D'Alessio, A.C.4
Sharma, S.5
Seckl, J.R.6
Dymov, S.7
Szyf, M.8
Meaney, M.J.9
-
68
-
-
28044436691
-
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: Altering epigenetic marking later in life
-
Weaver IC, Champagne FA, Brown SE, Dymov S, Sharma S,Meaney MJ, Szyf M. 2005. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: Altering epigenetic marking later in life. J Neurosci 25: 11045-11054.
-
(2005)
J Neurosci
, vol.25
, pp. 11045-11054
-
-
Weaver, I.C.1
Champagne, F.A.2
Brown, S.E.3
Dymov, S.4
Sharma, S.5
Meaney, M.J.6
Szyf, M.7
-
69
-
-
0033604609
-
Chromosomal landscape of nucleosome- dependent gene expression and silencing in yeast
-
Wyrick JJ, Holstege FC, Jennings EG, Causton HC, Shore D, Grunstein M, Lander ES, Young RA. 1999. Chromosomal landscape of nucleosome- dependent gene expression and silencing in yeast. Nature 402: 418-421.
-
(1999)
Nature
, vol.402
, pp. 418-421
-
-
Wyrick, J.J.1
Holstege, F.C.2
Jennings, E.G.3
Causton, H.C.4
Shore, D.5
Grunstein, M.6
Lander, E.S.7
Young, R.A.8
-
70
-
-
35448981923
-
Lsh controls Hox gene silencing during development
-
Xi S, Zhu H, Xu H, Schmidtmann A, Geiman TM, Muegge K. 2007. Lsh controls Hox gene silencing during development. Proc Natl Acad Sci 104: 14366-14371.
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 14366-14371
-
-
Xi, S.1
Zhu, H.2
Xu, H.3
Schmidtmann, A.4
Geiman, T.M.5
Muegge, K.6
-
71
-
-
79953143753
-
H3K36 methylation antagonizes PRC2-mediated H3K27 methylation
-
Yuan W, Xu M, Huang C, Liu N, Chen S, Zhu B. 2011. H3K36 methylation antagonizes PRC2-mediated H3K27 methylation. J Biol Chem 286: 7983-7989.
-
(2011)
J Biol Chem
, vol.286
, pp. 7983-7989
-
-
Yuan, W.1
Xu, M.2
Huang, C.3
Liu, N.4
Chen, S.5
Zhu, B.6
-
72
-
-
84865292901
-
Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation
-
Yuan W, Wu T, Fu H, Dai C, Wu H, Liu N, Li X, Xu M, Zhang Z, Niu T, et al. 2012. Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation. Science 337: 971-975.
-
(2012)
Science
, vol.337
, pp. 971-975
-
-
Yuan, W.1
Wu, T.2
Fu, H.3
Dai, C.4
Wu, H.5
Liu, N.6
Li, X.7
Xu, M.8
Zhang, Z.9
Niu, T.10
-
73
-
-
80455144479
-
Pioneer transcription factors: Establishing competence for gene expression
-
Zaret KS, Carroll JS. 2011. Pioneer transcription factors: Establishing competence for gene expression. Genes Dev 25: 2227-2241.
-
(2011)
Genes Dev
, vol.25
, pp. 2227-2241
-
-
Zaret, K.S.1
Carroll, J.S.2
-
74
-
-
74549129403
-
HMG modifications and nuclear function
-
Zhang Q,Wang Y. 2010. HMG modifications and nuclear function. Biochim Biophys Acta 1799: 28-36.
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 28-36
-
-
Zhang, Q.1
Wang, Y.2
-
75
-
-
84890432056
-
Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations
-
Zhang Y,Wong C-H, Birnbaum RY, Li G, Favaro R, Ngan CY, Lim J, Tai E, Poh HM, Wong E, et al. 2013. Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations. Nature 504: 306-310.
-
(2013)
Nature
, vol.504
, pp. 306-310
-
-
Zhang, Y.1
Wong, C.-H.2
Birnbaum, R.Y.3
Li, G.4
Favaro, R.5
Ngan, C.Y.6
Lim, J.7
Tai, E.8
Poh, H.M.9
Wong, E.10
-
76
-
-
84892562730
-
Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy
-
Zhao ZW, Roy R, Gebhardt JC, Suter DM, Chapman AR, Xie XS. 2014. Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy. Proc Natl Acad Sci 111: 681-686.
-
(2014)
Proc Natl Acad Sci
, vol.111
, pp. 681-686
-
-
Zhao, Z.W.1
Roy, R.2
Gebhardt, J.C.3
Suter, D.M.4
Chapman, A.R.5
Xie, X.S.6
|