Relaxin in paraventricular nucleus contributes to sympathetic overdrive and hypertension via PI3K-Akt pathway

Neuropharmacology

Volumn 103, Issue , 2016, Pages 247-256

  Sun, Hai Jian ^a   Chen, Dan ^a   Han, Ying ^a   Zhou, Ye Bo ^a   Wang, Jue Jin ^a   Chen, Qi ^a   Li, Yue Hua ^a   Gao, Xing Ya ^a   Kang, Yu Ming ^b   Zhu, Guo Qing ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Hypertension; Paraventricular nucleus; Relaxin; Sympathetic; Vasopressin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; ARGIPRESSIN; HEXAMETHONIUM; HORMONE RECEPTOR; IMMUNOGLOBULIN G; NORADRENALIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE P85ALPHA SUBUNIT; PROTEIN KINASE B; RELAXIN; RELAXIN FAMILY PEPTIDE RECEPTOR 1; RNA POLYMERASE II; SERELAXIN; STAT5A PROTEIN; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; LGR7 PROTEIN, RAT; RECEPTOR; RLN2 PROTEIN, HUMAN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC NEUROPATHY; BRAIN STEM; CARDIOVASCULAR DISEASE; CARDIOVASCULAR REMODELING; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HORMONE ACTION; HORMONE BLOOD LEVEL; HORMONE RELEASE; HYPERTENSION; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MAGNOCELLULAR NUCLEUS; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; NORADRENALIN BLOOD LEVEL; OSMOTIC PUMP; PARVOCELLULAR NUCLEUS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC NERVE CELL; SYMPATHETIC OVERDRIVE; SYMPATHETIC TONE; WISTAR KYOTO RAT; ADRENERGIC SYSTEM; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; HUMAN; METABOLISM; NERVE CELL;

ANIMALS; HUMANS; HYPERTENSION; MALE; NEURONS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PEPTIDE; RELAXIN; SIGNAL TRANSDUCTION; SYMPATHETIC NERVOUS SYSTEM;

EID: 84953296846     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2015.12.023     Document Type: Article

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