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Volumn 141, Issue 1, 2006, Pages 329-344

Comparative localization of leucine-rich repeat-containing g-protein-coupled receptor-7 (RXFP1) mRNA and [33P]-relaxin binding sites in rat brain: Restricted somatic co-expression a clue to relaxin action?

Author keywords

Cognition; G protein coupled receptor; In situ hybridization histochemistry; Insulin Relaxin peptide family; Olfaction; Radioligand autoradiography

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LGR7 PROTEIN, RAT; MESSENGER RNA; PHOSPHORUS; RECEPTOR; RELAXIN;

EID: 33749059602     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.03.076     Document Type: Article
Times cited : (46)

References (69)
  • 3
    • 33644589069 scopus 로고    scopus 로고
    • International Union of Pharmacology LVII: Recommendations for the nomenclature of receptors for relaxin family peptides
    • Bathgate RAD, Ivell R, Sanborn BM, Sherwood OD, Summers RJ (2006a) International Union of Pharmacology LVII: Recommendations for the nomenclature of receptors for relaxin family peptides. Pharmacol Rev 58:7-31.
    • (2006) Pharmacol Rev , vol.58 , pp. 7-31
    • Bathgate, R.A.D.1    Ivell, R.2    Sanborn, B.M.3    Sherwood, O.D.4    Summers, R.J.5
  • 7
    • 27844487052 scopus 로고    scopus 로고
    • A field guide to the anterior olfactory nucleus (cortex)
    • Brunjes PC, Illig KR, Meyer EA (2005) A field guide to the anterior olfactory nucleus (cortex). Brain Res Rev 50:305-335.
    • (2005) Brain Res Rev , vol.50 , pp. 305-335
    • Brunjes, P.C.1    Illig, K.R.2    Meyer, E.A.3
  • 8
    • 23644441631 scopus 로고    scopus 로고
    • Localization of LGR7 (relaxin receptor) mRNA and protein in rat forebrain: Correlation with relaxin binding site distribution
    • Burazin TCD, Johnson KJ, Ma S, Bathgate RAD, Tregear GW, Gundlach AL (2005) Localization of LGR7 (relaxin receptor) mRNA and protein in rat forebrain: Correlation with relaxin binding site distribution. Ann N Y Acad Sci 1041:205-210.
    • (2005) Ann N Y Acad Sci , vol.1041 , pp. 205-210
    • Burazin, T.C.D.1    Johnson, K.J.2    Ma, S.3    Bathgate, R.A.D.4    Tregear, G.W.5    Gundlach, A.L.6
  • 9
    • 0036734781 scopus 로고    scopus 로고
    • Restricted, but abundant, expression of the novel rat gene-3 (R3) relaxin in the dorsal tegmental region of brain
    • Burazin TCD, Bathgate RAD, Macris M, Layfield S, Gundlach AL, Tregear GW (2002) Restricted, but abundant, expression of the novel rat gene-3 (R3) relaxin in the dorsal tegmental region of brain. J Neurochem 82:1553-1557.
    • (2002) J Neurochem , vol.82 , pp. 1553-1557
    • Burazin, T.C.D.1    Bathgate, R.A.D.2    Macris, M.3    Layfield, S.4    Gundlach, A.L.5    Tregear, G.W.6
  • 10
    • 0037948140 scopus 로고    scopus 로고
    • Identification of relaxin and relaxin responsive cells in the rat brain
    • In: Proceedings of the third international conference on relaxin and related peptides (Tregear GW et al., eds), Dordrecht: Kluwer Academic Publishers
    • Burazin TCD, Davern P, McKinley MJ, Tregear GW (2001) Identification of relaxin and relaxin responsive cells in the rat brain. In: Proceedings of the third international conference on relaxin and related peptides (Tregear GW et al., eds), pp 209-214. Dordrecht: Kluwer Academic Publishers.
    • (2001) , pp. 209-214
    • Burazin, T.C.D.1    Davern, P.2    McKinley, M.J.3    Tregear, G.W.4
  • 11
    • 0036114221 scopus 로고    scopus 로고
    • Emotion and motivation: The role of the amygdala, ventral striatum, and prefrontal cortex
    • Cardinal RN, Parkinson JA, Hall J, Everitt BJ (2002) Emotion and motivation: The role of the amygdala, ventral striatum, and prefrontal cortex. Neurosci Biobehav Rev 26:321-352.
    • (2002) Neurosci Biobehav Rev , vol.26 , pp. 321-352
    • Cardinal, R.N.1    Parkinson, J.A.2    Hall, J.3    Everitt, B.J.4
  • 13
    • 0024418254 scopus 로고
    • Characterization of relaxin-stimulated cyclic amp in cultured rat anterior pituitary cells: Influence of dopamine, somatostatin and gender
    • Cronin MJ, Malaska T (1989) Characterization of relaxin-stimulated cyclic amp in cultured rat anterior pituitary cells: Influence of dopamine, somatostatin and gender. J Mol Endocrinol 3:175-182.
    • (1989) J Mol Endocrinol , vol.3 , pp. 175-182
    • Cronin, M.J.1    Malaska, T.2
  • 14
    • 0023150757 scopus 로고
    • Relaxin affects the release of oxytocin and vasopressin from the neurohypophysis
    • Dayanithi G, Cazalis M, Nordmann JJ (1987) Relaxin affects the release of oxytocin and vasopressin from the neurohypophysis. Nature 325:813-816.
    • (1987) Nature , vol.325 , pp. 813-816
    • Dayanithi, G.1    Cazalis, M.2    Nordmann, J.J.3
  • 16
    • 0029147781 scopus 로고
    • The emerging concept of relaxin as a centrally acting peptide hormone with hemodynamic actions
    • Geddes BJ, Summerlee AJS (1995) The emerging concept of relaxin as a centrally acting peptide hormone with hemodynamic actions. J Neuroendocrinol 7:411-417.
    • (1995) J Neuroendocrinol , vol.7 , pp. 411-417
    • Geddes, B.J.1    Summerlee, A.J.S.2
  • 18
    • 0026722452 scopus 로고
    • Circumventricular organ capillaries
    • Gross PM (1992) Circumventricular organ capillaries. Prog Brain Res 91:219-233.
    • (1992) Prog Brain Res , vol.91 , pp. 219-233
    • Gross, P.M.1
  • 19
    • 0034954421 scopus 로고    scopus 로고
    • Parallel-distributed processing in olfactory cortex: New insights from morphological and physiological analysis of neuronal circuitry
    • Haberly LB (2001) Parallel-distributed processing in olfactory cortex: New insights from morphological and physiological analysis of neuronal circuitry. Chem Senses 26:551-576.
    • (2001) Chem Senses , vol.26 , pp. 551-576
    • Haberly, L.B.1
  • 20
    • 0033360315 scopus 로고    scopus 로고
    • Amygdala activity related to enhanced memory for pleasant and aversive stimuli
    • Hamann SB, Ely TD, Grafton ST, Kilts CD (1999) Amygdala activity related to enhanced memory for pleasant and aversive stimuli. Nat Neurosci 2:289-293.
    • (1999) Nat Neurosci , vol.2 , pp. 289-293
    • Hamann, S.B.1    Ely, T.D.2    Grafton, S.T.3    Kilts, C.D.4
  • 22
    • 0034464024 scopus 로고    scopus 로고
    • The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): Identification of LGR6 and LGR7 and the signaling mechanism for LGR7
    • Hsu SY, Kudo M, Chen T, Nakabayashi K, Bhalla A, van der Spek PJ, van Duin M, Hsueh AJ (2000) The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): Identification of LGR6 and LGR7 and the signaling mechanism for LGR7. Mol Endocrinol 14:1257-1271.
    • (2000) Mol Endocrinol , vol.14 , pp. 1257-1271
    • Hsu, S.Y.1    Kudo, M.2    Chen, T.3    Nakabayashi, K.4    Bhalla, A.5    van der Spek, P.J.6    van Duin, M.7    Hsueh, A.J.8
  • 25
    • 0036721334 scopus 로고    scopus 로고
    • Reproductive biology of the relaxin-like factor (RLF/INSL3)
    • Ivell R, Bathgate RAD (2002) Reproductive biology of the relaxin-like factor (RLF/INSL3). Biol Reprod 67:699-705.
    • (2002) Biol Reprod , vol.67 , pp. 699-705
    • Ivell, R.1    Bathgate, R.A.D.2
  • 26
    • 0037396344 scopus 로고    scopus 로고
    • The molecular basis of cryptorchidism
    • Ivell R, Hartung S (2003) The molecular basis of cryptorchidism. Mol Hum Reprod 9:175-181.
    • (2003) Mol Hum Reprod , vol.9 , pp. 175-181
    • Ivell, R.1    Hartung, S.2
  • 27
    • 0034666287 scopus 로고    scopus 로고
    • New features of connectivity in piriform cortex visualized by intracellular injection of pyramidal cells suggest that 'primary' olfactory cortex functions like 'association' cortex in other sensory systems
    • Johnson DM, Illig KR, Behan M, Haberly LB (2000) New features of connectivity in piriform cortex visualized by intracellular injection of pyramidal cells suggest that 'primary' olfactory cortex functions like 'association' cortex in other sensory systems. J Neurosci 20: 6974-6982.
    • (2000) J Neurosci , vol.20 , pp. 6974-6982
    • Johnson, D.M.1    Illig, K.R.2    Behan, M.3    Haberly, L.B.4
  • 31
    • 11244347812 scopus 로고    scopus 로고
    • Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7
    • Liu C, Chen J, Kuei C, Sutton S, Nepomuceno D, Bonaventure P, Lovenberg TW (2005) Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7. Mol Pharmacol 67:231-240.
    • (2005) Mol Pharmacol , vol.67 , pp. 231-240
    • Liu, C.1    Chen, J.2    Kuei, C.3    Sutton, S.4    Nepomuceno, D.5    Bonaventure, P.6    Lovenberg, T.W.7
  • 34
    • 0020631031 scopus 로고
    • The topographic organization of associational fibers of the olfactory system in the rat, including centrifugal fibers to the olfactory bulb
    • Luskin MB, Price JL (1983) The topographic organization of associational fibers of the olfactory system in the rat, including centrifugal fibers to the olfactory bulb. J Comp Neurol 216:264-291.
    • (1983) J Comp Neurol , vol.216 , pp. 264-291
    • Luskin, M.B.1    Price, J.L.2
  • 37
    • 3943103488 scopus 로고    scopus 로고
    • The amygdala modulates the consolidation of memories of emotionally arousing experiences
    • McGaugh JL (2004) The amygdala modulates the consolidation of memories of emotionally arousing experiences. Annu Rev Neurosci 27:1-28.
    • (2004) Annu Rev Neurosci , vol.27 , pp. 1-28
    • McGaugh, J.L.1
  • 38
    • 0036881442 scopus 로고    scopus 로고
    • Amygdala modulation of memory consolidation: Interaction with other brain systems
    • McGaugh JL, McIntyre CK, Power AE (2002) Amygdala modulation of memory consolidation: Interaction with other brain systems. Neurobiol Learn Mem 78:539-552.
    • (2002) Neurobiol Learn Mem , vol.78 , pp. 539-552
    • McGaugh, J.L.1    McIntyre, C.K.2    Power, A.E.3
  • 39
    • 0030997318 scopus 로고    scopus 로고
    • Distribution of fos immunoreactivity in the lamina terminalis and hypothalamus induced by centrally administered relaxin in conscious rats
    • McKinley MJ, Burns P, Colvill LM, Oldfield BJ, Wade JD, Weisinger RS, Tregear GW (1997) Distribution of fos immunoreactivity in the lamina terminalis and hypothalamus induced by centrally administered relaxin in conscious rats. J Neuroendocrinol 9:431-437.
    • (1997) J Neuroendocrinol , vol.9 , pp. 431-437
    • McKinley, M.J.1    Burns, P.2    Colvill, L.M.3    Oldfield, B.J.4    Wade, J.D.5    Weisinger, R.S.6    Tregear, G.W.7
  • 42
    • 0027199629 scopus 로고
    • Expression of relaxin mRNA and relaxin receptors in postnatal and adult rat brains and hearts
    • Osheroff PL, Ho W-H (1993) Expression of relaxin mRNA and relaxin receptors in postnatal and adult rat brains and hearts. J Biol Chem 268:15193-15199.
    • (1993) J Biol Chem , vol.268 , pp. 15193-15199
    • Osheroff, P.L.1    Ho, W.-H.2
  • 43
    • 0025311303 scopus 로고
    • Preparation of biologically active 32P-labeled human relaxin. Displaceable binding to rat uterus, cervix, and brain.
    • Osheroff PL, Ling VT, Vandlen RL, Cronin MJ, Lofgren JA (1990) Preparation of biologically active 32P-labeled human relaxin. Displaceable binding to rat uterus, cervix, and brain. J Biol Chem 265:9396-9401.
    • (1990) J Biol Chem , vol.265 , pp. 9396-9401
    • Osheroff, P.L.1    Ling, V.T.2    Vandlen, R.L.3    Cronin, M.J.4    Lofgren, J.A.5
  • 44
    • 0026010298 scopus 로고
    • Autoradiographic localization of relaxin binding sites in rat brain
    • Osheroff PL, Phillips HS (1991) Autoradiographic localization of relaxin binding sites in rat brain. Proc Natl Acad Sci U S A 88: 6413-6417.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 6413-6417
    • Osheroff, P.L.1    Phillips, H.S.2
  • 46
    • 0028012739 scopus 로고
    • Effects of relaxin on blood pressure and the release of vasopressin and oxytocin in anesthetized rats during pregnancy and lactation
    • Parry LJ, Poterski RS, Summerlee AJ (1994) Effects of relaxin on blood pressure and the release of vasopressin and oxytocin in anesthetized rats during pregnancy and lactation. Biol Reprod 50:622-628.
    • (1994) Biol Reprod , vol.50 , pp. 622-628
    • Parry, L.J.1    Poterski, R.S.2    Summerlee, A.J.3
  • 47
    • 0003698235 scopus 로고    scopus 로고
    • The rat brain in stereotaxic coordinates
    • San Diego: Academic Press.
    • Paxinos G, Watson C (1997) The rat brain in stereotaxic coordinates. San Diego: Academic Press.
    • (1997)
    • Paxinos, G.1    Watson, C.2
  • 48
    • 23644445221 scopus 로고    scopus 로고
    • Localization of LGR7 gene expression in adult mouse brain using LGR7 knock-out/LacZ knock-in mice: Correlation with LGR7 mRNA distribution
    • Piccenna L, Shen P-J, Ma S, Burazin TCD, Gossen JA, Mosselman S, Bathgate RAD, Gundlach AL (2005) Localization of LGR7 gene expression in adult mouse brain using LGR7 knock-out/LacZ knock-in mice: Correlation with LGR7 mRNA distribution. Ann N Y Acad Sci 1041:197-204.
    • (2005) Ann N Y Acad Sci , vol.1041 , pp. 197-204
    • Piccenna, L.1    Shen, P.-J.2    Ma, S.3    Burazin, T.C.D.4    Gossen, J.A.5    Mosselman, S.6    Bathgate, R.A.D.7    Gundlach, A.L.8
  • 49
    • 0032081988 scopus 로고    scopus 로고
    • Orbitofrontal cortex and basolateral amygdala encode expected outcomes during learning
    • Schoenbaum G, Chiba AA, Gallagher M (1998) Orbitofrontal cortex and basolateral amygdala encode expected outcomes during learning. Nat Neurosci 1:155-159.
    • (1998) Nat Neurosci , vol.1 , pp. 155-159
    • Schoenbaum, G.1    Chiba, A.A.2    Gallagher, M.3
  • 52
    • 0018769393 scopus 로고
    • Purification and characterization of rat relaxin
    • Sherwood OD (1979) Purification and characterization of rat relaxin. Endocrinology 104:886-892.
    • (1979) Endocrinology , vol.104 , pp. 886-892
    • Sherwood, O.D.1
  • 53
    • 0033303539 scopus 로고    scopus 로고
    • Water drinking in rats resulting from intravenous relaxin and its modification by other dipsogenic factors
    • Sinnayah P, Burns P, Wade JD, Weisinger RS, McKinley MJ (1999) Water drinking in rats resulting from intravenous relaxin and its modification by other dipsogenic factors. Endocrinology 140:5082-5086.
    • (1999) Endocrinology , vol.140 , pp. 5082-5086
    • Sinnayah, P.1    Burns, P.2    Wade, J.D.3    Weisinger, R.S.4    McKinley, M.J.5
  • 54
    • 0024507755 scopus 로고
    • Relaxin stimulates prolactin secretion from anterior pituitary cells
    • Sortino MA, Cronin MJ, Wise PM (1989) Relaxin stimulates prolactin secretion from anterior pituitary cells. Endocrinology 124:2013-2015.
    • (1989) Endocrinology , vol.124 , pp. 2013-2015
    • Sortino, M.A.1    Cronin, M.J.2    Wise, P.M.3
  • 55
    • 0037424265 scopus 로고    scopus 로고
    • H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2
    • Sudo S, Kumagai J, Nishi S, Layfield S, Ferraro T, Bathgate RAD, Hsueh AJ (2003) H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2. J Biol Chem 278:7855-7862.
    • (2003) J Biol Chem , vol.278 , pp. 7855-7862
    • Sudo, S.1    Kumagai, J.2    Nishi, S.3    Layfield, S.4    Ferraro, T.5    Bathgate, R.A.D.6    Hsueh, A.J.7
  • 56
    • 0031790532 scopus 로고    scopus 로고
    • The dipsogenic effects of rat relaxin: The effect of photoperiod and the potential role of relaxin on drinking in pregnancy
    • Summerlee AJ, Hornsby DJ, Ramsey DG (1998a) The dipsogenic effects of rat relaxin: The effect of photoperiod and the potential role of relaxin on drinking in pregnancy. Endocrinology 139:2322-2328.
    • (1998) Endocrinology , vol.139 , pp. 2322-2328
    • Summerlee, A.J.1    Hornsby, D.J.2    Ramsey, D.G.3
  • 57
    • 0031788013 scopus 로고    scopus 로고
    • Neutralization of relaxin within the brain affects the timing of birth in rats
    • Summerlee AJ, Ramsey DG, Poterski RS (1998b) Neutralization of relaxin within the brain affects the timing of birth in rats. Endocrinology 139:479-484.
    • (1998) Endocrinology , vol.139 , pp. 479-484
    • Summerlee, A.J.1    Ramsey, D.G.2    Poterski, R.S.3
  • 59
    • 15544378102 scopus 로고    scopus 로고
    • Distribution of G-protein-coupled receptor (GPCR)135 binding sites and receptor mRNA in the rat brain suggests a role for relaxin-3 in neuroendocrine and sensory processing
    • Sutton SW, Bonaventure P, Kuei C, Roland B, Chen J, Nepomuceno D, Lovenberg TW, Liu C (2004) Distribution of G-protein-coupled receptor (GPCR)135 binding sites and receptor mRNA in the rat brain suggests a role for relaxin-3 in neuroendocrine and sensory processing. Neuroendocrinology 80:298-307.
    • (2004) Neuroendocrinology , vol.80 , pp. 298-307
    • Sutton, S.W.1    Bonaventure, P.2    Kuei, C.3    Roland, B.4    Chen, J.5    Nepomuceno, D.6    Lovenberg, T.W.7    Liu, C.8
  • 60
    • 33646510279 scopus 로고    scopus 로고
    • G-protein-coupled receptor (GPCR)-142 does not contribute to relaxin-3 binding in the mouse brain: Further support that relaxin-3 is the physiological ligand for GPCR135
    • Sutton SW, Bonaventure P, Kuei C, Nepomuceno D, Wu J, Zhu J, Lovenberg TW, Liu C (2006) G-protein-coupled receptor (GPCR)-142 does not contribute to relaxin-3 binding in the mouse brain: Further support that relaxin-3 is the physiological ligand for GPCR135. Neuroendocrinology 82:139-150.
    • (2006) Neuroendocrinology , vol.82 , pp. 139-150
    • Sutton, S.W.1    Bonaventure, P.2    Kuei, C.3    Nepomuceno, D.4    Wu, J.5    Zhu, J.6    Lovenberg, T.W.7    Liu, C.8
  • 61
    • 0003479813 scopus 로고    scopus 로고
    • Brain maps: Structure of the rat brain
    • 2nd ed. Amsterdam: Elsevier.
    • Swanson LW (1998/1999) Brain maps: Structure of the rat brain, 2nd ed. Amsterdam: Elsevier.
    • (1998)
    • Swanson, L.W.1
  • 62
    • 0032908730 scopus 로고    scopus 로고
    • Quantitative autoradiographic studies of relaxin binding in rat atria, uterus and cerebral cortex: Characterization and effects of oestrogen treatment
    • Tan YY, Wade JD, Tregear GW, Summers RJ (1999) Quantitative autoradiographic studies of relaxin binding in rat atria, uterus and cerebral cortex: Characterization and effects of oestrogen treatment. Br J Pharmacol 127:91-98.
    • (1999) Br J Pharmacol , vol.127 , pp. 91-98
    • Tan, Y.Y.1    Wade, J.D.2    Tregear, G.W.3    Summers, R.J.4
  • 64
    • 0028914083 scopus 로고
    • The effects of centrally administered porcine relaxin on drinking behaviour in male and female rats
    • Thornton SM, Fitzsimons JT (1995) The effects of centrally administered porcine relaxin on drinking behaviour in male and female rats. J Neuroendocrinol 7:165-169.
    • (1995) J Neuroendocrinol , vol.7 , pp. 165-169
    • Thornton, S.M.1    Fitzsimons, J.T.2
  • 65
    • 0026512506 scopus 로고
    • Relaxin increases the firing rate of supraoptic neurones and increases oxytocin secretion in the rat
    • Way SA, Leng G (1992) Relaxin increases the firing rate of supraoptic neurones and increases oxytocin secretion in the rat. J Endocrinol 132:149-158.
    • (1992) J Endocrinol , vol.132 , pp. 149-158
    • Way, S.A.1    Leng, G.2
  • 67
    • 0036048569 scopus 로고    scopus 로고
    • In situ hybridization with oligonucleotide probes
    • Wisden W, Morris BJ (2002) In situ hybridization with oligonucleotide probes. Int Rev Neurobiol 47:3-59.
    • (2002) Int Rev Neurobiol , vol.47 , pp. 3-59
    • Wisden, W.1    Morris, B.J.2
  • 69
    • 0032844333 scopus 로고    scopus 로고
    • Evidence that IGF-I acts as an autocrine/paracrine growth factor in the magnocellular neurosecretory system: Neuronal synthesis and induction of axonal sprouting
    • Zhou X, Herman JP, Paden CM (1999) Evidence that IGF-I acts as an autocrine/paracrine growth factor in the magnocellular neurosecretory system: Neuronal synthesis and induction of axonal sprouting. Exp Neurol 159:419-432.
    • (1999) Exp Neurol , vol.159 , pp. 419-432
    • Zhou, X.1    Herman, J.P.2    Paden, C.M.3


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