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Volumn 196, Issue 1, 2016, Pages 448-458

Nck binds to the T cell antigen receptor using its SH3.1 and SH2 domains in a cooperative manner, promoting TCR functioning

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD3E PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; NCK PROTEIN; ONCOPROTEIN; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 84953284853     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500958     Document Type: Article
Times cited : (21)

References (46)
  • 1
    • 0036015163 scopus 로고    scopus 로고
    • The Nck family of adapter proteins: Regulators of actin cytoskeleton
    • Buday, L., L. Wunderlich, and P. Tamás. 2002. The Nck family of adapter proteins: regulators of actin cytoskeleton. Cell. Signal. 14: 723-731.
    • (2002) Cell. Signal. , vol.14 , pp. 723-731
    • Buday, L.1    Wunderlich, L.2    Tamás, P.3
  • 2
    • 84877990371 scopus 로고    scopus 로고
    • Nck adapter proteins: Functional versatility in T cells
    • Lettau, M., J. Pieper, and O. Janssen. 2009. Nck adapter proteins: functional versatility in T cells. Cell Commun. Signal. 7: 1.
    • (2009) Cell Commun. Signal. , vol.7 , pp. 1
    • Lettau, M.1    Pieper, J.2    Janssen, O.3
  • 4
    • 0031434747 scopus 로고    scopus 로고
    • Pre-TCR/CD3 and TCR/CD3 complexes: Decamers with differential signalling properties? Immunol
    • Jacobs, H. 1997. Pre-TCR/CD3 and TCR/CD3 complexes: decamers with differential signalling properties? Immunol. Today 18: 565-569.
    • (1997) Today , vol.18 , pp. 565-569
    • Jacobs, H.1
  • 5
    • 0037306051 scopus 로고    scopus 로고
    • Initiation of TCR signaling: Regulation within CD3 dimers
    • Alarcón, B., D. Gil, P. Delgado, and W. W. Schamel. 2003. Initiation of TCR signaling: regulation within CD3 dimers. Immunol. Rev. 191: 38-46.
    • (2003) Immunol. Rev. , vol.191 , pp. 38-46
    • Alarcón, B.1    Gil, D.2    Delgado, P.3    Schamel, W.W.4
  • 6
    • 77956419470 scopus 로고    scopus 로고
    • ITAM-mediated signaling by the T-cell antigen receptor
    • Love, P. E., and S. M. Hayes. 2010. ITAM-mediated signaling by the T-cell antigen receptor. Cold Spring Harb. Perspect. Biol. 2: a002485.
    • (2010) Cold Spring Harb. Perspect. Biol. , vol.2 , pp. a002485
    • Love, P.E.1    Hayes, S.M.2
  • 7
    • 0024980981 scopus 로고
    • Antigen receptor tail clue
    • Reth, M. 1989. Antigen receptor tail clue. Nature 338: 383-384.
    • (1989) Nature , vol.338 , pp. 383-384
    • Reth, M.1
  • 8
    • 0035124549 scopus 로고    scopus 로고
    • T cell receptor signalling
    • Lin, J., and A. Weiss. 2001. T cell receptor signalling. J. Cell Sci. 114: 243-244.
    • (2001) J. Cell Sci. , vol.114 , pp. 243-244
    • Lin, J.1    Weiss, A.2
  • 9
    • 70350414453 scopus 로고    scopus 로고
    • Organization of proximal signal initiation at the TCR:CD3 complex
    • Guy, C. S., and D. A. Vignali. 2009. Organization of proximal signal initiation at the TCR:CD3 complex. Immunol. Rev. 232: 7-21.
    • (2009) Immunol. Rev. , vol.232 , pp. 7-21
    • Guy, C.S.1    Vignali, D.A.2
  • 10
    • 0032910208 scopus 로고    scopus 로고
    • Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes
    • Wunderlich, L., A. Faragó, J. Downward, and L. Buday. 1999. Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes. Eur. J. Immunol. 29: 1068-1075.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 1068-1075
    • Wunderlich, L.1    Faragó, A.2    Downward, J.3    Buday, L.4
  • 11
  • 12
    • 77956090599 scopus 로고    scopus 로고
    • Coordination of receptor signaling in multiple hematopoietic cell lineages by the adaptor protein SLP-76
    • Jordan, M. S., and G. A. Koretzky. 2010. Coordination of receptor signaling in multiple hematopoietic cell lineages by the adaptor protein SLP-76. Cold Spring Harb. Perspect. Biol. 2: a002501.
    • (2010) Cold Spring Harb. Perspect. Biol. , vol.2 , pp. a002501
    • Jordan, M.S.1    Koretzky, G.A.2
  • 13
    • 0037188899 scopus 로고    scopus 로고
    • Recruitment of Nck by CD3ε reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation
    • Gil, D., W. W. Schamel, M. Montoya, F. Sánchez-Madrid, and B. Alarcón. 2002. Recruitment of Nck by CD3ε reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Cell 109: 901-912.
    • (2002) Cell , vol.109 , pp. 901-912
    • Gil, D.1    Schamel, W.W.2    Montoya, M.3    Sánchez-Madrid, F.4    Alarcón, B.5
  • 15
    • 33846224785 scopus 로고    scopus 로고
    • Full activation of the T cell receptor requires both clustering and conformational changes at CD3
    • Minguet, S., M. Swamy, B. Alarcón, I. F. Luescher, and W. W. Schamel. 2007. Full activation of the T cell receptor requires both clustering and conformational changes at CD3. Immunity 26: 43-54.
    • (2007) Immunity , vol.26 , pp. 43-54
    • Minguet, S.1    Swamy, M.2    Alarcón, B.3    Luescher, I.F.4    Schamel, W.W.5
  • 17
    • 84914816489 scopus 로고    scopus 로고
    • Conformational changes in the T cell receptor differentially determine T cell subset development in mice
    • Blanco, R., A. Borroto, W. Schamel, P. Pereira, and B. Alarcon. 2014. Conformational changes in the T cell receptor differentially determine T cell subset development in mice. Sci. Signal. 7: ra115.
    • (2014) Sci. Signal. , vol.7 , pp. ra115
    • Blanco, R.1    Borroto, A.2    Schamel, W.3    Pereira, P.4    Alarcon, B.5
  • 18
    • 14244262563 scopus 로고    scopus 로고
    • T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytes
    • Gil, D., A. G. Schrum, B. Alarcón, and E. Palmer. 2005. T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytes. J. Exp. Med. 201: 517-522.
    • (2005) J. Exp. Med. , vol.201 , pp. 517-522
    • Gil, D.1    Schrum, A.G.2    Alarcón, B.3    Palmer, E.4
  • 19
    • 22144493855 scopus 로고    scopus 로고
    • Ligand-induced conformational change in the T-cell receptor associated with productive immune synapses
    • Risueño, R. M., D. Gil, E. Fernández, F. Sánchez-Madrid, and B. Alarcón. 2005. Ligand-induced conformational change in the T-cell receptor associated with productive immune synapses. Blood 106: 601-608.
    • (2005) Blood , vol.106 , pp. 601-608
    • Risueño, R.M.1    Gil, D.2    Fernández, E.3    Sánchez-Madrid, F.4    Alarcón, B.5
  • 20
    • 33745435793 scopus 로고    scopus 로고
    • A conformational change senses the strength of T cell receptor-ligand interaction during thymic selection
    • Risueño, R. M., H. M. van Santen, and B. Alarcón. 2006. A conformational change senses the strength of T cell receptor-ligand interaction during thymic selection. Proc. Natl. Acad. Sci. USA 103: 9625-9630.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 9625-9630
    • Risueño, R.M.1    Van Santen, H.M.2    Alarcón, B.3
  • 24
    • 2642612819 scopus 로고    scopus 로고
    • Assembly of the TCR/CD3 complex: CD3ε/d and CD3ε/g dimers associate indistinctly with both TCR a and TCR b chains. Evidence for a double TCR heterodimer model
    • San José, E., A. G. Sahuquillo, R. Bragado, and B. Alarcón. 1998. Assembly of the TCR/CD3 complex: CD3ε/d and CD3ε/g dimers associate indistinctly with both TCR a and TCR b chains. Evidence for a double TCR heterodimer model. Eur. J. Immunol. 28: 12-21.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 12-21
    • San José, E.1    Sahuquillo, A.G.2    Bragado, R.3    Alarcón, B.4
  • 27
    • 0031080595 scopus 로고    scopus 로고
    • Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein
    • Lu, W., S. Katz, R. Gupta, and B. J. Mayer. 1997. Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck. Curr. Biol. 7: 85-94.
    • (1997) Nck. Curr. Biol. , vol.7 , pp. 85-94
    • Lu, W.1    Katz, S.2    Gupta, R.3    Mayer, B.J.4
  • 28
    • 0033623198 scopus 로고    scopus 로고
    • Nckb adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to plateletderived growth factor bb
    • Chen, M., H. She, A. Kim, D. T. Woodley, and W. Li. 2000. Nckb adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to plateletderived growth factor bb. Mol. Cell. Biol. 20: 7867-7880.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7867-7880
    • Chen, M.1    She, H.2    Kim, A.3    Woodley, D.T.4    Li, W.5
  • 29
    • 0028789982 scopus 로고
    • Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins
    • Tanaka, M., R. Gupta, and B. J. Mayer. 1995. Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins. Mol. Cell. Biol. 15: 6829-6837.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6829-6837
    • Tanaka, M.1    Gupta, R.2    Mayer, B.J.3
  • 32
    • 34548732682 scopus 로고    scopus 로고
    • Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3ε
    • Kesti, T., A. Ruppelt, J. H. Wang, M. Liss, R. Wagner, K. Taskén, and K. Saksela. 2007. Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3ε. J. Immunol. 179: 878-885.
    • (2007) J. Immunol. , vol.179 , pp. 878-885
    • Kesti, T.1    Ruppelt, A.2    Wang, J.H.3    Liss, M.4    Wagner, R.5    Taskén, K.6    Saksela, K.7
  • 33
    • 45649085424 scopus 로고    scopus 로고
    • Structural and functional evidence that Nck interaction with CD3ε regulates T-cell receptor activity
    • Takeuchi, K., H. Yang, E. Ng, S. Y. Park, Z. Y. Sun, E. L. Reinherz, and G. Wagner. 2008. Structural and functional evidence that Nck interaction with CD3ε regulates T-cell receptor activity. J. Mol. Biol. 380: 704-716.
    • (2008) J. Mol. Biol. , vol.380 , pp. 704-716
    • Takeuchi, K.1    Yang, H.2    Ng, E.3    Park, S.Y.4    Sun, Z.Y.5    Reinherz, E.L.6    Wagner, G.7
  • 34
    • 56449107760 scopus 로고    scopus 로고
    • Interaction between the N-terminal SH3 domain of Nck-α and CD3- ε-derived peptides: Non-canonical and canonical recognition motifs
    • Santiveri, C. M., A. Borroto, L. Simón, M. Rico, B. Alarcón, and M. A. Jiménez. 2009. Interaction between the N-terminal SH3 domain of Nck-α and CD3- ε-derived peptides: non-canonical and canonical recognition motifs. Biochim. Biophys. Acta 1794: 110-117.
    • (2009) Biochim. Biophys. Acta , vol.1794 , pp. 110-117
    • Santiveri, C.M.1    Borroto, A.2    Simón, L.3    Rico, M.4    Alarcón, B.5    Jiménez, M.A.6
  • 37
    • 0034086261 scopus 로고    scopus 로고
    • Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation
    • Villalba, M., J. Hernandez, M. Deckert, Y. Tanaka, and A. Altman. 2000. Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation. Eur. J. Immunol. 30: 1587-1596.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1587-1596
    • Villalba, M.1    Hernandez, J.2    Deckert, M.3    Tanaka, Y.4    Altman, A.5
  • 38
    • 0032563231 scopus 로고    scopus 로고
    • Fidelity of T cell activation through multistep T cell receptor z phosphorylation
    • Kersh, E. N., A. S. Shaw, and P. M. Allen. 1998. Fidelity of T cell activation through multistep T cell receptor z phosphorylation. Science 281: 572-575.
    • (1998) Science , vol.281 , pp. 572-575
    • Kersh, E.N.1    Shaw, A.S.2    Allen, P.M.3
  • 39
    • 0037769031 scopus 로고    scopus 로고
    • T cell antagonism is functionally uncoupled from the 21- and 23-kDa tyrosine-phosphorylated TCR z subunits
    • Pitcher, L. A., P. S. Ohashi, and N. S. van Oers. 2003. T cell antagonism is functionally uncoupled from the 21- and 23-kDa tyrosine-phosphorylated TCR z subunits. J. Immunol. 171: 845-852.
    • (2003) J. Immunol. , vol.171 , pp. 845-852
    • Pitcher, L.A.1    Ohashi, P.S.2    Van Oers, N.S.3
  • 41
    • 0037304542 scopus 로고    scopus 로고
    • All roads lead to actin: The intimate relationship between TCR signaling and the cytoskeleton
    • Fuller, C. L., V. L. Braciale, and L. E. Samelson. 2003. All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton. Immunol. Rev. 191: 220-236.
    • (2003) Immunol. Rev. , vol.191 , pp. 220-236
    • Fuller, C.L.1    Braciale, V.L.2    Samelson, L.E.3
  • 42
    • 0041845112 scopus 로고    scopus 로고
    • SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site
    • Zeng, R., J. L. Cannon, R. T. Abraham, M. Way, D. D. Billadeau, J. Bubeck- Wardenberg, and J. K. Burkhardt. 2003. SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site. J. Immunol. 171: 1360-1368.
    • (2003) J. Immunol. , vol.171 , pp. 1360-1368
    • Zeng, R.1    Cannon, J.L.2    Abraham, R.T.3    Way, M.4    Billadeau, D.D.5    Bubeck-Wardenberg, J.6    Burkhardt, J.K.7
  • 44
    • 34548233165 scopus 로고    scopus 로고
    • Calcium signalling in lymphocyte activation and disease
    • Feske, S. 2007. Calcium signalling in lymphocyte activation and disease. Nat. Rev. Immunol. 7: 690-702.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 690-702
    • Feske, S.1


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