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Volumn 171, Issue 2, 2003, Pages 845-852

T cell antagonism is functionally uncoupled from the 21- and 23-kDa tyrosine-phosphorylated TCR ζ subunits

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P21; PROTEIN P23; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA ZETA; TYROSINE; UNCLASSIFIED DRUG;

EID: 0037769031     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.2.845     Document Type: Article
Times cited : (15)

References (42)
  • 1
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss, A., and D. R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263.
    • (1994) Cell , vol.76 , pp. 263
    • Weiss, A.1    Littman, D.R.2
  • 2
    • 0024980981 scopus 로고
    • Antigen receptor tail clue
    • Reth, M. 1989. Antigen receptor tail clue. Nature 338:383.
    • (1989) Nature , vol.338 , pp. 383
    • Reth, M.1
  • 3
    • 0030250114 scopus 로고    scopus 로고
    • Complex complexes: Signaling at the TCR
    • Wange, R. L., and L. E. Samelson. 1996. Complex complexes: signaling at the TCR. Immunity 5:197.
    • (1996) Immunity , vol.5 , pp. 197
    • Wange, R.L.1    Samelson, L.E.2
  • 4
    • 0028988331 scopus 로고
    • T cell receptor antagonists and partial agonists
    • Jameson, S. C., and M. J. Bevan. 1995. T cell receptor antagonists and partial agonists. Immunity 2:1.
    • (1995) Immunity , vol.2 , pp. 1
    • Jameson, S.C.1    Bevan, M.J.2
  • 6
    • 0029933309 scopus 로고    scopus 로고
    • Altered peptide ligand induced partial T cell activation: Molecular mechanisms and role in T cell biology
    • Sloan-Lancaster, J., and P. M. Allen. 1996. Altered peptide ligand induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu. Rev. Immunol. 14:1.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 1
    • Sloan-Lancaster, J.1    Allen, P.M.2
  • 7
    • 0033666867 scopus 로고    scopus 로고
    • ITAM multiplicity and thymocyte selection: How long can you go
    • Love, P. E., and E. W. Shores. 2000. ITAM multiplicity and thymocyte selection: how long can you go. Immunity 12:591.
    • (2000) Immunity , vol.12 , pp. 591
    • Love, P.E.1    Shores, E.W.2
  • 8
    • 0026544338 scopus 로고
    • The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules
    • Wegener, A.-M. K., F. Letourneur, A. Hoeveler, T. Brocker, F. Luton, and B. Malissen. 1992. The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell 68:83.
    • (1992) Cell , vol.68 , pp. 83
    • Wegener, A.-M.K.1    Letourneur, F.2    Hoeveler, A.3    Brocker, T.4    Luton, F.5    Malissen, B.6
  • 10
    • 0024446403 scopus 로고
    • + thymocytes results in tyrosine phosphorylation of the T-cell receptor ζ chain
    • + thymocytes results in tyrosine phosphorylation of the T-cell receptor ζ chain. Nature 341:651.
    • (1989) Nature , vol.341 , pp. 651
    • Nakayama, T.1    Singer, A.2    Hsi, E.D.3    Samelson, L.E.4
  • 11
    • 0028535120 scopus 로고
    • ZAP-70 is constitutively associated with tyrosine phosphorylated TCR ζ in murine thymocytes and lymph node T cells
    • van Oers, N. S. C., N. Killeen, and A. Weiss. 1994. ZAP-70 is constitutively associated with tyrosine phosphorylated TCR ζ in murine thymocytes and lymph node T cells. Immunity 1:675.
    • (1994) Immunity , vol.1 , pp. 675
    • Van Oers, N.S.C.1    Killeen, N.2    Weiss, A.3
  • 13
    • 0034665510 scopus 로고    scopus 로고
    • Critical relationship between TCR signaling potential and TCR affinity during thymocyte selection
    • Love, P. E., J. Lee, and E. W. Shores. 2000. Critical relationship between TCR signaling potential and TCR affinity during thymocyte selection. J. Immunol. 165:3080.
    • (2000) J. Immunol. , vol.165 , pp. 3080
    • Love, P.E.1    Lee, J.2    Shores, E.W.3
  • 14
    • 0028902752 scopus 로고
    • ζ phosphorylation without ZAP-70 activation induced by T cell receptor antagonists or partial agonists
    • Madrenas, J., R. L. Wange, J. L. Wang, N. Isakov, L. E. Samelson, and R. N. Germain. 1995. ζ Phosphorylation without ZAP-70 activation induced by T cell receptor antagonists or partial agonists. Science 267:515.
    • (1995) Science , vol.267 , pp. 515
    • Madrenas, J.1    Wange, R.L.2    Wang, J.L.3    Isakov, N.4    Samelson, L.E.5    Germain, R.N.6
  • 15
    • 0027967385 scopus 로고
    • Partial T cell signaling: Altered phospho-ζ and lack of ZAP-70 recruitment in APL-induced T cell anergy
    • Sloan-Lancaster, J., A. S. Shaw, J. B. Rothbard, and P. M. Allen. 1994. Partial T cell signaling: altered phospho-ζ and lack of ZAP-70 recruitment in APL-induced T cell anergy. Cell 79:913.
    • (1994) Cell , vol.79 , pp. 913
    • Sloan-Lancaster, J.1    Shaw, A.S.2    Rothbard, J.B.3    Allen, P.M.4
  • 17
    • 0033404953 scopus 로고    scopus 로고
    • Partially phosphorylated T cell receptor ζ molecules can inhibit T cell activation
    • Kersh, E. N., G. J. Kersh, and P. M. Allen. 1999. Partially phosphorylated T cell receptor ζ molecules can inhibit T cell activation. J. Exp. Med. 190:1627.
    • (1999) J. Exp. Med. , vol.190 , pp. 1627
    • Kersh, E.N.1    Kersh, G.J.2    Allen, P.M.3
  • 19
    • 0032493277 scopus 로고    scopus 로고
    • Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes
    • Published erratum appears in 1998 Proc. Natl. Acad. Sci. USA 95:13348.
    • Smyth, L. A., O. Williams, R. D. Huby, T. Norton, O. Acuto, S. C. Ley, and D. Kioussis. 1998. Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes. [Published erratum appears in 1998 Proc. Natl. Acad. Sci. USA 95:13348.] Proc. Natl. Acad. Sci. USA 95:8193.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8193
    • Smyth, L.A.1    Williams, O.2    Huby, R.D.3    Norton, T.4    Acuto, O.5    Ley, S.C.6    Kioussis, D.7
  • 20
    • 0033565718 scopus 로고    scopus 로고
    • Differential CD3 ζ phosphorylation is not required for the induction of T cell antagonism by altered peptide ligands
    • Liu, H., and D. A. Vignali. 1999. Differential CD3 ζ phosphorylation is not required for the induction of T cell antagonism by altered peptide ligands. J. Immunol. 163:599.
    • (1999) J. Immunol. , vol.163 , pp. 599
    • Liu, H.1    Vignali, D.A.2
  • 21
    • 0031883421 scopus 로고    scopus 로고
    • Regulation of T cell receptor signal transduction in murine thymocytes by multiple TCR ζ-chain signaling motifs
    • van Oers, N. S. C., P. Love, E. W. Shores, and A. Weiss. 1998. Regulation of T cell receptor signal transduction in murine thymocytes by multiple TCR ζ-chain signaling motifs. J. Immunol. 160:163.
    • (1998) J. Immunol. , vol.160 , pp. 163
    • Van Oers, N.S.C.1    Love, P.2    Shores, E.W.3    Weiss, A.4
  • 24
    • 0030046923 scopus 로고
    • Dominant-negative ZAP-70 inhibits T cell antigen receptor signaling
    • Qian, D., M. Mollenauer, and A. Weiss. 1995, Dominant-negative ZAP-70 inhibits T cell antigen receptor signaling. J. Exp. Med. 183:611.
    • (1995) J. Exp. Med. , vol.183 , pp. 611
    • Qian, D.1    Mollenauer, M.2    Weiss, A.3
  • 25
    • 0028877062 scopus 로고
    • The pre-TCR complex is functionally coupled to the TCR ζ subunit
    • van Oers, N. S. C., H. von Boehmer, and A. Weiss. 1995. The pre-TCR complex is functionally coupled to the TCR ζ subunit. J. Exp. Med, 182:1585.
    • (1995) J. Exp. Med. , vol.182 , pp. 1585
    • Van Oers, N.S.C.1    Von Boehmer, H.2    Weiss, A.3
  • 26
    • 0029037960 scopus 로고
    • Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice
    • Zhumabekov, T., P. Corbella, M. Toliani, and D. Kioussis. 1995. Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice. J. Immunol. Methods 185:133.
    • (1995) J. Immunol. Methods , vol.185 , pp. 133
    • Zhumabekov, T.1    Corbella, P.2    Toliani, M.3    Kioussis, D.4
  • 27
    • 0030772120 scopus 로고    scopus 로고
    • Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation
    • Bachmann, M. F., A. Oxenius, D. E. Speiser, S. Mariathasan, H. Hengartner, R. M. Zinkernagel, and P. S. Ohashi. 1997. Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation. Eur. J. Immunol. 27:2195.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2195
    • Bachmann, M.F.1    Oxenius, A.2    Speiser, D.E.3    Mariathasan, S.4    Hengartner, H.5    Zinkernagel, R.M.6    Ohashi, P.S.7
  • 28
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher, H.-P., K. Burki, R. Lang, H. Hengartner, and R. Zinkernagel. 1989. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342:559.
    • (1989) Nature , vol.342 , pp. 559
    • Pircher, H.-P.1    Burki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.5
  • 30
    • 0033178653 scopus 로고    scopus 로고
    • T cell receptor-mediated signs and signals governing T cell development
    • van Oers, N. S. 1999. T cell receptor-mediated signs and signals governing T cell development. Semin. Immunol. 11:227.
    • (1999) Semin. Immunol. , vol.11 , pp. 227
    • Van Oers, N.S.1
  • 31
    • 0027228369 scopus 로고
    • Constitutive tyrosine phosphorylation of the T cell receptor (TCR) ζ subunit: Regulation of TCR-associated protein kinase activity by TCR ζ
    • van Oers, N. S. C., W. Tao, J. D. Watts, P. Johnson, R. Aebersold, and H.-S. Teh. 1993. Constitutive tyrosine phosphorylation of the T cell receptor (TCR) ζ subunit: regulation of TCR-associated protein kinase activity by TCR ζ. Mol. Cell. Biol. 13:5771.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5771
    • Van Oers, N.S.C.1    Tao, W.2    Watts, J.D.3    Johnson, P.4    Aebersold, R.5    Teh, H.-S.6
  • 33
    • 0027298445 scopus 로고
    • Induction of T cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells
    • Sloan-Lancaster, J., B. D. Evavold, and P. M. Allen. 1993. Induction of T cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells. Nature 363:156.
    • (1993) Nature , vol.363 , pp. 156
    • Sloan-Lancaster, J.1    Evavold, B.D.2    Allen, P.M.3
  • 34
    • 0032563231 scopus 로고    scopus 로고
    • Fidelity of T cell activation through multistep T cell receptor ζ phosphorylation
    • Kersh, E. N., A. S. Shaw, and P. M. Allen. 1998. Fidelity of T cell activation through multistep T cell receptor ζ phosphorylation. Science 281:572.
    • (1998) Science , vol.281 , pp. 572
    • Kersh, E.N.1    Shaw, A.S.2    Allen, P.M.3
  • 35
    • 0033199986 scopus 로고    scopus 로고
    • Cross-antagonism of a T cell clone expressing two distinct T cell receptors
    • Dittel, B. N., I. Stefanova, R. N. Germain, and C. A. Janeway, Jr. 1999. Cross-antagonism of a T cell clone expressing two distinct T cell receptors. Immunity 11:289.
    • (1999) Immunity , vol.11 , pp. 289
    • Dittel, B.N.1    Stefanova, I.2    Germain, R.N.3    Janeway C.A., Jr.4
  • 36
    • 0032966863 scopus 로고    scopus 로고
    • Negative regulation of the JAK/STAT pathway
    • Starr, R., and D. J. Hilton. 1999. Negative regulation of the JAK/STAT pathway. BioEssays 21:47.
    • (1999) BioEssays , vol.21 , pp. 47
    • Starr, R.1    Hilton, D.J.2
  • 37
    • 0028970289 scopus 로고
    • Integral membrane protein 2 of Epstein Barr virus regulates reactivation from latency through dominant negative effects on protein tyrosine kinases
    • Miller, C. L., A. L. Burkhardt, J. H. Lee, B. Stealey, R. Longnecker, J. B. Bolen, and E. Kieff. 1995. Integral membrane protein 2 of Epstein Barr virus regulates reactivation from latency through dominant negative effects on protein tyrosine kinases. Immunity 2:155.
    • (1995) Immunity , vol.2 , pp. 155
    • Miller, C.L.1    Burkhardt, A.L.2    Lee, J.H.3    Stealey, B.4    Longnecker, R.5    Bolen, J.B.6    Kieff, E.7
  • 38
    • 0030754766 scopus 로고    scopus 로고
    • The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction
    • Fruehling, S., and R. Longnecker. 1997. The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction. Virology 235:241.
    • (1997) Virology , vol.235 , pp. 241
    • Fruehling, S.1    Longnecker, R.2
  • 39
    • 0028088994 scopus 로고
    • An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking
    • Miller, C. L., J. H. Lee, E. Kieff, and R. Longnecker. 1994. An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking. Proc. Natl. Acad. Sci. USA 91:772.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 772
    • Miller, C.L.1    Lee, J.H.2    Kieff, E.3    Longnecker, R.4
  • 40
    • 0033545865 scopus 로고    scopus 로고
    • Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus
    • Lagunoff, M., R. Majeti, A. Weiss, and D. Ganem. 1999. Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus. Proc. Natl. Acad. Sci. USA 96:5704.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5704
    • Lagunoff, M.1    Majeti, R.2    Weiss, A.3    Ganem, D.4
  • 41
    • 0033120578 scopus 로고    scopus 로고
    • Cutting edge: A test of the dominant negative signal model for TCR antagonism
    • Daniels, M. A., S. L. Schober, K. A. Hogquist, and S. C. Jameson. 1999. Cutting edge: a test of the dominant negative signal model for TCR antagonism. J. Immunol 162:3761.
    • (1999) J. Immunol , vol.162 , pp. 3761
    • Daniels, M.A.1    Schober, S.L.2    Hogquist, K.A.3    Jameson, S.C.4
  • 42
    • 0033579813 scopus 로고    scopus 로고
    • T cell receptor (TCR) antagonism without a negative signal: Evidence from T cell hybridomas expressing two independent TCRs
    • Stotz, S. H., L. Bolliger, F. R. Carbone, and E. Palmer. 1999. T cell receptor (TCR) antagonism without a negative signal: evidence from T cell hybridomas expressing two independent TCRs. J. Exp. Med. 189:253.
    • (1999) J. Exp. Med. , vol.189 , pp. 253
    • Stotz, S.H.1    Bolliger, L.2    Carbone, F.R.3    Palmer, E.4


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