Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection

PLoS Pathogens

Volumn 11, Issue 12, 2015, Pages

  Wilde, Aimee D ^a   Snyder, Daniel J ^a   Putnam, Nicole E ^a   Valentino, Michael D ^b,g   Hammer, Neal D ^a   Lonergan, Zachery R ^a   Hinger, Scott A ^c   Aysanoa, Esar E ^a   Blanchard, Catlyn ^d   Dunman, Paul M ^d   Wasserman, Gregory A ^e,h   Chen, John ^e,i   Shopsin, Bo ^e   Gilmore, Michael S ^b   Skaar, Eric P ^a,f   Cassat, James E ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c VANDERBILT UNIVERSITY   (United States)

^d UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Veteran's Affairs Tennessee Valley Healthcare System   (United States)

^g Exosome Diagnostics   (United States)

^h BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIUM MUTANT; BIOLUMINESCENCE; COLONY FORMING UNIT; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; HOST PATHOGEN INTERACTION; HYPOXIA; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOMYELITIS; OXYGEN CONCENTRATION; POLYMERASE CHAIN REACTION; RNA ISOLATION; SEQUENCE ANALYSIS; STAPHYLOCOCCUS INFECTION; ANIMAL; C57BL MOUSE; CELL HYPOXIA; CELL LINE; DISEASE MODEL; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MICROBIOLOGY; PATHOGENICITY; QUORUM SENSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS; TRANSPOSON; VIRULENCE; VIRUS GENE;

TRANSPOSON; VIRULENCE FACTOR;

ANIMALS; CELL HYPOXIA; CELL LINE; DISEASE MODELS, ANIMAL; DNA TRANSPOSABLE ELEMENTS; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; GENES, VIRAL; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOMYELITIS; QUORUM SENSING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; VIRULENCE; VIRULENCE FACTORS;

EID: 84953246804     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005341     Document Type: Article

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