Green tea catechins prevent low-density lipoprotein oxidation via their accumulation in low-density lipoprotein particles in humans

Nutrition Research

Volumn 36, Issue 1, 2016, Pages 16-23

  Suzuki Sugihara, Norie ^a   Kishimoto, Yoshimi ^a   Saita, Emi ^a   Taguchi, Chie ^a   Kobayashi, Makoto ^b   Ichitani, Masaki ^b   Ukawa, Yuuichi ^b   Sagesaka, Yuko M ^b   Suzuki, Emiko ^a   Kondo, Kazuo ^a,c  

^a OCHANOMIZU UNIVERSITY   (Japan)

^b H   (Japan)

^c TOYO UNIVERSITY   (Japan)

Author keywords

Epigallocatechin gallate; Humans; Lipid peroxidation; Lipoproteins; Low density lipoprotein; Tea

Indexed keywords

CATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; GREEN TEA EXTRACT; LOW DENSITY LIPOPROTEIN; ANTIOXIDANT; BIOLOGICAL MARKER; OXIDIZED LOW DENSITY LIPOPROTEIN; PLANT EXTRACT;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG MECHANISM; FEMALE; HUMAN; IN VITRO STUDY; INCUBATION TIME; INGESTION; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BLOOD; CAMELLIA SINENSIS; CHEMISTRY; CLINICAL TRIAL; DIETARY SUPPLEMENT; JAPAN; METABOLISM; MIDDLE AGED; OXIDATION REDUCTION REACTION; PLANT LEAF; RISK FACTOR; YOUNG ADULT;

ADULT; ANTIOXIDANTS; ATHEROSCLEROSIS; BIOMARKERS; CAMELLIA SINENSIS; CATECHIN; CROSS-OVER STUDIES; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; JAPAN; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; OXIDATION-REDUCTION; PLANT EXTRACTS; PLANT LEAVES; RISK FACTORS; YOUNG ADULT;

EID: 84953237931     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2015.10.012     Document Type: Article

References (46)

1. Steinberg D., Parthasarathy S., Carew T.E., Khoo J.C., Witztum J.L. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 1989, 320:915-924.
2. Steinberg D. The LDL, modification hypothesis of atherogenesis: an update. J Lipid Res 2009, 50:S376-S381. [Suppl.].
3. Hertog M.G., Feskens E.J., Kromhout D. Antioxidant flavonols and coronary heart disease risk. Lancet 1997, 349:699.
4. Huxley R.R., Neil H.A. The relation between dietary flavonol intake and coronary heart disease mortality: a meta-analysis of prospective cohort studies. Eur J Clin Nutr 2003, 57:904-908.
5. Fukushima Y., Ohie T., Yonekawa Y., Yonemoto K., Aizawa H., Mori Y., et al. Coffee and green tea as a large source of antioxidant polyphenols in the Japanese population. J Agric Food Chem 2009, 57:1253-1259.
6. Taguchi C., Fukushima Y., Kishimoto Y., Saita E., Suzuki-Sugihara N., Yoshida D., et al. Polyphenol intake from beverages in Japan over an 18-year period (1996-2013): trends by year, age, gender and season. J Nutr Sci Vitaminol (Tokyo) 2015, 61:338-344.
7. Fukushima Y., Tashiro T., Kumagai A., Ohyanagi H., Horiuchi T., Takizawa K., et al. Coffee and beverages are the major contributors to polyphenol consumption from food and beverages in Japanese middle-aged women. J Nutr Sci 2014, 3:e48.
8. Saito E., Inoue M., Sawada N., Shimazu T., Yamaji T., Iwasaki M., et al. Association of green tea consumption with mortality due to all causes and major causes of death in a Japanese population: the Japan Public Health Center-based Prospective Study (JPHC Study). Ann Epidemiol 2015, 25:512-518 e3.
9. Nagao T., Hase T., Tokimitsu I. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity (Silver Spring) 2007, 15:1473-1483.
10. Khalesi S., Sun J., Buys N., Jamshidi A., Nikbakht-Nasrabadi E., Khosravi-Boroujeni H. Green tea catechins and blood pressure: a systematic review and meta-analysis of randomised controlled trials. Eur J Nutr 2014, 53:1299-1311.
11. Tsuneki H., Ishizuka M., Terasawa M., Wu J.B., Sasaoka T., Kimura I. Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans. BMC Pharmacol 2004, 4:18.
12. Hirano-Ohmori R., Takahashi R., Momiyama Y., Taniguchi H., Yonemura A., Tamai S., et al. Green tea consumption and serum malondialdehyde-modified LDL concentrations in healthy subjects. J Am Coll Nutr 2005, 24:342-346.
13. Ohmori R., Kondo K., Momiyama Y. Antioxidant beverages: green tea intake and coronary artery disease. Clin Med Insight Cardiol 2014, 8:7-11.
14. Zheng Y., Morris A., Sunkara M., Layne J., Toborek M., Hennig B. Epigallocatechin-gallate stimulates NF-E2-related factor and heme oxygenase-1 via caveolin-1 displacement. J Nutr Biochem 2012, 23:163-168.
15. Naito Y., Yoshikawa T. Green tea and heart health. J Cardiovasc Pharmacol 2009, 54:385-390.
16. Hirano R., Sasamoto W., Matsumoto A., Itakura H., Igarashi O., Kondo K. Antioxidant ability of various flavonoids against DPPH radicals and LDL oxidation. J Nutr Sci Vitaminol (Tokyo) 2001, 47:357-362.
17. Ohmori R., Iwamoto T., Tago M., Takeo T., Unno T., Itakura H., et al. Antioxidant activity of various teas against free radicals and LDL oxidation. Lipids 2005, 40:849-853.
18. Nakagawa K., Ninomiya M., Okubo T., Aoi N., Juneja L.R., Kim M., et al. Tea catechin supplementation increases antioxidant capacity and prevents phospholipid hydroperoxidation in plasma of humans. J Agric Food Chem 1999, 47:3967-3973.
19. Miyazawa T. Absorption, metabolism and antioxidative effects of tea catechin in humans. Biofactors 2000, 13:55-59.
20. Nakagawa K., Okuda S., Miyazawa T. Dose-dependent incorporation of tea catechins, (-)-epigallocatechin-3-gallate and (-)-epigallocatechin, into human plasma. Biosci Biotechnol Biochem 1997, 61:1981-1985.
21. Lee M.J., Maliakal P., Chen L., Meng X., Bondoc F.Y., Prabhu S., et al. Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability. Cancer Epidemiol Biomarkers Prev 2002, 11:1025-1032.
22. Lee M.J., Wang Z.Y., Li H., Chen L., Sun Y., Gobbo S., et al. Analysis of plasma and urinary tea polyphenols in human subjects. Cancer Epidemiol Biomarkers Prev 1995, 4:393-399.
23. Chung B.H., Segrest J.P., Ray M.J., Brunzell J.D., Hokanson J.E., Krauss R.M., et al. Single vertical spin density gradient ultracentrifugation. Methods Enzymol 1986, 128:181-209.
24. Lourenco C.F., Gago B., Barbosa R.M., de Freitas V., Laranjinha J. LDL isolated from plasma-loaded red wine procyanidins resist lipid oxidation and tocopherol depletion. J Agric Food Chem 2008, 56:3798-3804.
25. Wu C.H., Lin J.A., Hsieh W.C., Yen G.C. Low-density-lipoprotein (LDL)-bound flavonoids increase the resistance of LDL to oxidation and glycation under pathophysiological concentrations of glucose in vitro. J Agric Food Chem 2009, 57:5058-5064.
26. Faul F., Erdfelder E., Lang A.G., Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007, 39:175-191.
27. Nakayama S., Kishimoto Y., Saita E., Sugihara N., Toyozaki M., Taguchi C., et al. Pine bark extract prevents low-density lipoprotein oxidation and regulates monocytic expression of antioxidant enzymes. Nutr Res 2015, 35:56-64.
28. Unno T., Sagesaka Y.M., Kakuda T. Analysis of tea catechins in human plasma by high-performance liquid chromatography with solid-phase extraction. J Agric Food Chem 2005, 53:9885-9889.
29. Nakagawa K., Nakayama K., Nakamura M., Sookwong P., Tsuduki T., Niino H., et al. Effects of co-administration of tea epigallocatechin-3-gallate (EGCG) and caffeine on absorption and metabolism of EGCG in humans. Biosci Biotechnol Biochem 2009, 73:2014-2017.
30. Spáčila Zdeněk, Nováková Lucie, Solich Petr Comparison of positive and negative ion detection of tea catechins using tandem mass spectrometry and ultra high performance liquid chromatography. Food Chem 2010, 123:535-541.
31. Miller N.J., Rice-Evans C.A. Factors influencing the antioxidant activity determined by the ABTS.+ radical cation assay. Free Radic Res 1997, 26:195-199.
32. Zhu Q.Y., Huang Y., Tsang D., Chen Z.Y. Regeneration of alpha-tocopherol in human low-density lipoprotein by green tea catechin. J Agric Food Chem 1999, 47:2020-2025.
33. Ishii T., Ichikawa T., Minoda K., Kusaka K., Ito S., Suzuki Y., et al. Human serum albumin as an antioxidant in the oxidation of (-)-epigallocatechin gallate: participation of reversible covalent binding for interaction and stabilization. Biosci Biotechnol Biochem 2011, 75:100-106.
34. Chow H.H., Cai Y., Alberts D.S., Hakim I., Dorr R., Shahi F., et al. Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E. Cancer Epidemiol Biomarkers Prev 2001, 10:53-58.
35. Shimoi K., Okada H., Furugori M., Goda T., Takase S., Suzuki M., et al. Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans. FEBS Lett 1998, 438:220-224.
36. Piskula M.K., Terao J. Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues. J Nutr 1998, 128:1172-1178.
37. Manach C., Morand C., Texier O., Favier M.L., Agullo G., Demigne C., et al. Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin. J Nutr 1995, 125:1911-1922.
38. Natsume M., Osakabe N., Yasuda A., Baba S., Tokunaga T., Kondo K., et al. in vitro antioxidative activity of (-)-epicatechin glucuronide metabolites present in human and rat plasma. Free Radic Res 2004, 38:1341-1348.
39. Oritani Y., Setoguchi Y., Ito R., Maruki-Uchida H., Ichiyanagi T., Ito T. Comparison of (-)-epigallocatechin-3-O-gallate (EGCG) and O-methyl EGCG bioavailability in rats. Biol Pharm Bull 2013, 36:1577-1582.
40. van het Hof K.H., Wiseman S.A., Yang C.S., Tijburg L.B. Plasma and lipoprotein levels of tea catechins following repeated tea consumption. Proc Soc Exp Biol Med 1999, 220:203-209.
41. Kobayashi M., Nishizawa M., Inoue N., Hosoya T., Yoshida M., Ukawa Y., et al. Epigallocatechin gallate decreases the micellar solubility of cholesterol via specific interaction with phosphatidylcholine. J Agric Food Chem 2014, 62:2881-2890.
42. Muramatsu K., Fukuyo M., Hara Y. Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats. J Nutr Sci Vitaminol (Tokyo) 1986, 32:613-622.
43. Ikeda I., Imasato Y., Sasaki E., Nakayama M., Nagao H., Takeo T., et al. Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. Biochim Biophys Acta 1992, 1127:141-146.
44. Ikeda I., Kobayashi M., Hamada T., Tsuda K., Goto H., Imaizumi K., et al. Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate. J Agric Food Chem 2003, 51:7303-7307.
45. Kajimoto O., Kajimoto Y., Yabune M., Nozawa A., Nagata K., Kakuda T. Tea catechins reduce serum cholesterol levels in mild and borderline hypercholesterolemia patients. J Clin Biochem Nutr 2003, 33:101-111.
46. Rose G., Shipley M. Plasma cholesterol concentration and death from coronary heart disease: 10 year results of the Whitehall study. Br Med J (Clin Res Ed) 1986, 293:306-307.