-
1
-
-
77953669219
-
The epidemiology of osteosarcoma
-
Ottaviani G and Jaffe N: The epidemiology of osteosarcoma. Cancer Treat Res 152: 3-13, 2009.
-
(2009)
Cancer Treat Res
, vol.152
, pp. 3-13
-
-
Ottaviani, G.1
Jaffe, N.2
-
4
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N and Sonenberg N: Upstream and downstream of mTOR. Genes Dev 18: 1926-1945, 2004.
-
(2004)
Genes Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
5
-
-
40349106029
-
The potential role of mTOR inhibitors in non-small cell lung cancer
-
Gridelli C, Maione P and Rossi A: The potential role of mTOR inhibitors in non-small cell lung cancer. Oncologist 13: 139-147, 2008.
-
(2008)
Oncologist
, vol.13
, pp. 139-147
-
-
Gridelli, C.1
Maione, P.2
Rossi, A.3
-
6
-
-
34447293996
-
The role of mTOR inhibitors for treatment of sarcomas
-
Mita MM and Tolcher AW: The role of mTOR inhibitors for treatment of sarcomas. Curr Oncol Rep 9: 316-322, 2007.
-
(2007)
Curr Oncol Rep
, vol.9
, pp. 316-322
-
-
Mita, M.M.1
Tolcher, A.W.2
-
7
-
-
33845974091
-
Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling
-
Kim KW, Mutter RW, Cao C, Albert JM, Freeman M, Hallahan DE and Lu B: Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling. J Biol Chem 281: 36883-36890, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 36883-36890
-
-
Kim, K.W.1
Mutter, R.W.2
Cao, C.3
Albert, J.M.4
Freeman, M.5
Hallahan, D.E.6
Lu, B.7
-
8
-
-
70350317873
-
6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/mTOR pathway in human non-small cell lung cancer A549 cells
-
Hung JY, Hsu YL, Li CT, Ko YC, Ni WC, Huang MS and Kuo PL: 6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/mTOR pathway in human non-small cell lung cancer A549 cells. J Agric Food Chem 57: 9809-9816, 2009.
-
(2009)
J Agric Food Chem
, vol.57
, pp. 9809-9816
-
-
Hung, J.Y.1
Hsu, Y.L.2
Li, C.T.3
Ko, Y.C.4
Ni, W.C.5
Huang, M.S.6
Kuo, P.L.7
-
9
-
-
67349114222
-
Programmed cell death pathways and current antitumor targets
-
Tan ML, Ooi JP, Ismail N, Moad AI and Muhammad TS: Programmed cell death pathways and current antitumor targets. Pharm Res 26: 1547-1560, 2009.
-
(2009)
Pharm Res
, vol.26
, pp. 1547-1560
-
-
Tan, M.L.1
Ooi, J.P.2
Ismail, N.3
Moad, A.I.4
Muhammad, T.S.5
-
10
-
-
84859778293
-
MTOR signaling in growth control and disease
-
Laplante M and Sabatini DM: mTOR signaling in growth control and disease. Cell 149: 274-293, 2012.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
11
-
-
78650510609
-
MTOR: From growth signal integration to cancer, diabetes and ageing
-
Zoncu R, Efeyan A and Sabatini DM: mTOR: From growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 12: 21-35, 2011.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
12
-
-
84883146054
-
The evolution of the TOR pathway and its role in cancer
-
B eauchamp EM and Platanias LC: The evolution of the TOR pathway and its role in cancer. Oncogene 32: 3923-3932, 2013.
-
(2013)
Oncogene
, vol.32
, pp. 3923-3932
-
-
Beauchamp, E.M.1
Platanias, L.C.2
-
13
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik D and Kimchi A: Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23: 2891-2906, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
14
-
-
53549127988
-
CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation
-
Roca H, Varsos Z and Pienta KJ: CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation. J Biol Chem 283: 25057-25073, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 25057-25073
-
-
Roca, H.1
Varsos, Z.2
Pienta, K.J.3
-
15
-
-
43949120765
-
Apoptosis meets autophagy-like cell death in the ischemic penumbra: Two sides of the same coin?
-
Rami A and Kögel D: Apoptosis meets autophagy-like cell death in the ischemic penumbra: Two sides of the same coin? Autophagy 4: 422-426, 2008.
-
(2008)
Autophagy
, vol.4
, pp. 422-426
-
-
Rami, A.1
Kögel, D.2
-
16
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
Kondo Y, Kanzawa T, Sawaya R and Kondo S: The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 5: 726-734, 2005.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
17
-
-
79952244140
-
Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells
-
Liu D, Yang Y, Liu Q and Wang J: Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells. Med Oncol 28: 105-111, 2011.
-
(2011)
Med Oncol
, vol.28
, pp. 105-111
-
-
Liu, D.1
Yang, Y.2
Liu, Q.3
Wang, J.4
-
18
-
-
77958609008
-
Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells
-
Kanematsu S, Uehara N, Miki H, Yoshizawa K, Kawanaka A, Yuri T and Tsubura A: Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells. Anticancer Res 30: 3381-3390, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 3381-3390
-
-
Kanematsu, S.1
Uehara, N.2
Miki, H.3
Yoshizawa, K.4
Kawanaka, A.5
Yuri, T.6
Tsubura, A.7
-
19
-
-
70449704645
-
Autophagy inhibition through PI3K/Akt increases apoptosis by sodium selenite in NB4 cells
-
Ren Y, Huang F, Liu Y, Yang Y, Jiang Q and Xu C: Autophagy inhibition through PI3K/Akt increases apoptosis by sodium selenite in NB4 cells. BMB Rep 42: 599-604, 2009.
-
(2009)
BMB Rep
, vol.42
, pp. 599-604
-
-
Ren, Y.1
Huang, F.2
Liu, Y.3
Yang, Y.4
Jiang, Q.5
Xu, C.6
-
20
-
-
80053501671
-
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13
-
Liu J, Xia H, Kim M, Xu L, Li Y, Zhang L, Cai Y, Norberg HV, Zhang T, Furuya T, et al: Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13. Cell 147: 223-234, 2011.
-
(2011)
Cell
, vol.147
, pp. 223-234
-
-
Liu, J.1
Xia, H.2
Kim, M.3
Xu, L.4
Li, Y.5
Zhang, L.6
Cai, Y.7
Norberg, H.V.8
Zhang, T.9
Furuya, T.10
-
21
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G and Johansen T: p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 282: 24131-24145, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.A.5
Outzen, H.6
Øvervatn, A.7
Bjørkøy, G.8
Johansen, T.9
-
22
-
-
44449141488
-
Activation and function of the mTORC1 pathway in mast cells
-
Kim MS, Kuehn HS, Metcalfe DD and Gilfillan AM: Activation and function of the mTORC1 pathway in mast cells. J Immunol 180: 4586-4595, 2008.
-
(2008)
J Immunol
, vol.180
, pp. 4586-4595
-
-
Kim, M.S.1
Kuehn, H.S.2
Metcalfe, D.D.3
Gilfillan, A.M.4
-
23
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky DJ and Emr SD: Autophagy as a regulated pathway of cellular degradation. Science 290: 1717-1721, 2000.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
24
-
-
4344595626
-
Regulation and role of autophagy in mammalian cells
-
Meijer AJ and Codogno P: Regulation and role of autophagy in mammalian cells. Int J Biochem Cell Biol 36: 2445-2462, 2004.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2445-2462
-
-
Meijer, A.J.1
Codogno, P.2
-
25
-
-
84917691452
-
Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells
-
Mori M, Hitora T, Nakamura O, Yamagami Y, Horie R, Nishimura H and Yamamoto T: Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells. Int J Oncol 46: 47-54, 2015.
-
(2015)
Int J Oncol
, vol.46
, pp. 47-54
-
-
Mori, M.1
Hitora, T.2
Nakamura, O.3
Yamagami, Y.4
Horie, R.5
Nishimura, H.6
Yamamoto, T.7
-
26
-
-
84897415977
-
Suppression of autophagy by chloroquine sensitizes 5-fluorouracil-mediated cell death in gallbladder carcinoma cells
-
Liang X, Tang J, Liang Y, Jin R and Cai X: Suppression of autophagy by chloroquine sensitizes 5-fluorouracil-mediated cell death in gallbladder carcinoma cells. Cell Biosci 4: 10, 2014.
-
(2014)
Cell Biosci
, vol.4
, pp. 10
-
-
Liang, X.1
Tang, J.2
Liang, Y.3
Jin, R.4
Cai, X.5
-
27
-
-
58749105634
-
Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway
-
Liu B, Cheng Y, Zhang B, Bian HJ and Bao JK: Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway. Cancer Lett 275: 54-60, 2009.
-
(2009)
Cancer Lett
, vol.275
, pp. 54-60
-
-
Liu, B.1
Cheng, Y.2
Zhang, B.3
Bian, H.J.4
Bao, J.K.5
-
28
-
-
79251593832
-
Induction of autophagydependent apoptosis by the survivin suppressant YM155 in prostate cancer cells
-
Wang Q, Chen Z, Diao X and Huang S: Induction of autophagydependent apoptosis by the survivin suppressant YM155 in prostate cancer cells. Cancer Lett 302: 29-36, 2011.
-
(2011)
Cancer Lett
, vol.302
, pp. 29-36
-
-
Wang, Q.1
Chen, Z.2
Diao, X.3
Huang, S.4
-
29
-
-
84899584514
-
The combination of rapamycin and MAPK inhibitors enhances the growth inhibitory effect on Nara-H cells
-
Nakamura O, Hitora T, Yamagami Y, Mori M, Nishimura H, Horie R, Yamaguchi K and Yamamoto T: The combination of rapamycin and MAPK inhibitors enhances the growth inhibitory effect on Nara-H cells. Int J Mol Med 33: 1491-1497, 2014.
-
(2014)
Int J Mol Med
, vol.33
, pp. 1491-1497
-
-
Nakamura, O.1
Hitora, T.2
Yamagami, Y.3
Mori, M.4
Nishimura, H.5
Horie, R.6
Yamaguchi, K.7
Yamamoto, T.8
-
30
-
-
84906828707
-
Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability
-
Correa RJ, Valdes YR, Peart TM, Fazio EN, Bertrand M, McGee J, Préfontaine M, Sugimoto A, DiMattia GE and Shepherd TG: Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability. Carcinogenesis 35: 1951-1961, 2014.
-
(2014)
Carcinogenesis
, vol.35
, pp. 1951-1961
-
-
Correa, R.J.1
Valdes, Y.R.2
Peart, T.M.3
Fazio, E.N.4
Bertrand, M.5
McGee, J.6
Préfontaine, M.7
Sugimoto, A.8
DiMattia, G.E.9
Shepherd, T.G.10
-
31
-
-
77149128638
-
Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells
-
Nishikawa T, Tsuno NH, Okaji Y, Shuno Y, Sasaki K, Hongo K, Sunami E, Kitayama J, Takahashi K and Nagawa H: Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells. Ann Surg Oncol 17: 592-602, 2010.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 592-602
-
-
Nishikawa, T.1
Tsuno, N.H.2
Okaji, Y.3
Shuno, Y.4
Sasaki, K.5
Hongo, K.6
Sunami, E.7
Kitayama, J.8
Takahashi, K.9
Nagawa, H.10
-
32
-
-
80054813644
-
Inhibition of induced autophagy increases apoptosis of Nara-H cells
-
Nakamura O, Hitora T, Akisue T, Kawamoto T, Yamagami Y and Yamamoto T: Inhibition of induced autophagy increases apoptosis of Nara-H cells. Int J Oncol 39: 1545-1552, 2011.
-
(2011)
Int J Oncol
, vol.39
, pp. 1545-1552
-
-
Nakamura, O.1
Hitora, T.2
Akisue, T.3
Kawamoto, T.4
Yamagami, Y.5
Yamamoto, T.6
|