-
1
-
-
0042807701
-
Expression of stem cell factor and c-kit in human malignant fibrous histiocytoma cell line (TNMY1)
-
Nakatani T, Marui T, Yamamoto T, et al.: Expression of stem cell factor and c-kit in human malignant fibrous histiocytoma cell line (TNMY1). Anticancer Res 23: 2329-2333, 2003. (Pubitemid 36897099)
-
(2003)
Anticancer Research
, vol.23
, Issue.3 B
, pp. 2329-2333
-
-
Nakatani, T.1
Marui, T.2
Yamamoto, T.3
Hitora, T.4
Akisue, T.5
Kawamoto, T.6
Nagira, K.7
Fujita, I.8
Matsumoto, K.9
Yoshiya, S.10
Kurosaka, M.11
-
2
-
-
42549105463
-
Inhibition of PKCalpha activation in human bone and soft tissue sarcoma cells by the selective PKC inhibitor PKC412
-
Kawamoto T, Akisue T, Kishimoto K, et al.: Inhibition of PKCalpha activation in human bone and soft tissue sarcoma cells by the selective PKC inhibitor PKC412. Anticancer Res 28: 825-832, 2008. (Pubitemid 351578926)
-
(2008)
Anticancer Research
, vol.28
, Issue.2 A
, pp. 825-832
-
-
Kawamoto, T.1
Akisue, T.2
Kishimoto, K.3
Hara, H.4
Imabori, M.5
Fujimoto, T.6
Kurosaka, M.7
Hitora, T.8
Kawaguchi, Y.9
Yamamoto, T.10
-
3
-
-
34548427415
-
The biology behind mTOR inhibition in sarcoma
-
DOI 10.1634/theoncologist.12-8-1007
-
Wan X and Helman LJ: The biology behind mTOR inhibition in sarcoma. Oncologist 12: 1007-1018, 2007. (Pubitemid 47359144)
-
(2007)
Oncologist
, vol.12
, Issue.8
, pp. 1007-1018
-
-
Wan, X.1
Helman, L.J.2
-
4
-
-
4043171462
-
Upstream and downstream of mTOR
-
DOI 10.1101/gad.1212704
-
Hay N and Sonenberg N: Upstream and downstream of mTOR. Genes Dev 18: 1926-1945, 2004. (Pubitemid 39071573)
-
(2004)
Genes and Development
, vol.18
, Issue.16
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
5
-
-
40349106029
-
The potential role of mTOR inhibitors in non-small cell lung cancer
-
DOI 10.1634/theoncologist.2007-0171
-
Gridelli C, Maione P and Rossi A: The potential role of mTOR inhibitors in non-small cell lung cancer. Oncologist 13: 139-147, 2008. (Pubitemid 351342577)
-
(2008)
Oncologist
, vol.13
, Issue.2
, pp. 139-147
-
-
Gridelli, C.1
Maione, P.2
Rossi, A.3
-
6
-
-
34447293996
-
The role of mTOR inhibitors for treatment of sarcomas
-
DOI 10.1007/s11912-007-0039-7
-
Mita MM and Tolcher AW: The role of mTOR inhibitors for treatment of sarcomas. Curr Oncol Rep 9: 316-322, 2007. (Pubitemid 47045166)
-
(2007)
Current Oncology Reports
, vol.9
, Issue.4
, pp. 316-322
-
-
Mita, M.M.1
Tolcher, A.W.2
-
7
-
-
33645690146
-
In vivo antitumor effect of the mTOR inhibitor CCI-779 and gemcitabine in xenograft models of human pancreatic cancer
-
Ito D, Fujimoto K, Mori T, et al.: In vivo antitumor effect of the mTOR inhibitor CCI-779 and gemcitabine in xenograft models of human pancreatic cancer. Int J Cancer 118: 2337-2343, 2006.
-
(2006)
Int J Cancer
, vol.118
, pp. 2337-2343
-
-
Ito, D.1
Fujimoto, K.2
Mori, T.3
-
8
-
-
33750072949
-
mTOR and cancer therapy
-
DOI 10.1038/sj.onc.1209886, PII 1209886
-
Easton JB and Houghton PJ: mTOR and cancer therapy. Oncogene 25: 6436-6446, 2006. (Pubitemid 44582287)
-
(2006)
Oncogene
, vol.25
, Issue.48
, pp. 6436-6446
-
-
Easton, J.B.1
Houghton, P.J.2
-
9
-
-
33845974091
-
Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling
-
DOI 10.1074/jbc.M607094200
-
Kim KW, Mutter RW, Cao C, et al.: Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling. J Biol Chem 281: 36883-36890, 2006. (Pubitemid 46042156)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.48
, pp. 36883-36890
-
-
Kwang, W.K.1
Mutter, R.W.2
Cao, C.3
Albert, J.M.4
Freeman, M.5
Hallahan, D.E.6
Lu, B.7
-
10
-
-
70350317873
-
6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/ mTOR pathway in human non-small cell lung cancer A549 cells
-
Hung JY, Hsu YL, Li CT, et al.: 6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/ mTOR pathway in human non-small cell lung cancer A549 cells. J Agric Food Chem 57: 9809-9816, 2009.
-
(2009)
J Agric Food Chem
, vol.57
, pp. 9809-9816
-
-
Hung, J.Y.1
Hsu, Y.L.2
Li, C.T.3
-
11
-
-
67349114222
-
Programmed cell death pathways and current antitumor targets
-
Tan ML, Ooi JP, Ismail N, Moad AI and Muhammad TS: Programmed cell death pathways and current antitumor targets. Pharm Res 26: 1547-1560, 2009.
-
(2009)
Pharm Res
, vol.26
, pp. 1547-1560
-
-
Tan, M.L.1
Ooi, J.P.2
Ismail, N.3
Moad, A.I.4
Muhammad, T.S.5
-
12
-
-
37549056216
-
The roles of therapy-induced autophagy and necrosis in cancer treatment
-
Amaravadi RK and Thompson CB: The roles of therapy-induced autophagy and necrosis in cancer treatment. Clin Cancer Res 13: 7271-7279, 2007.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7271-7279
-
-
Amaravadi, R.K.1
Thompson, C.B.2
-
13
-
-
38749136302
-
Regulation of macroautophagy by mTOR and Beclin 1 complexes
-
DOI 10.1016/j.biochi.2007.08.014, PII S0300908407002283
-
Pattingre S, Espert L, Biard-Piechaczyk M and Codogno P: Regulation of macroautophagy by mTOR and Beclin 1 complexes. Biochimie 90: 313-323, 2008. (Pubitemid 351181247)
-
(2008)
Biochimie
, vol.90
, Issue.2
, pp. 313-323
-
-
Pattingre, S.1
Espert, L.2
Biard-Piechaczyk, M.3
Codogno, P.4
-
14
-
-
79952244140
-
Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells
-
In press
-
Liu D, Yang Y, Liu Q and Wang J: Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells. Med Oncol (In press).
-
Med Oncol
-
-
Liu, D.1
Yang, Y.2
Liu, Q.3
Wang, J.4
-
15
-
-
77958609008
-
Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells
-
Kanematsu S, Uehara N, Miki H, et al.: Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells. Anticancer Res 30: 3381-3390, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 3381-3390
-
-
Kanematsu, S.1
Uehara, N.2
Miki, H.3
-
16
-
-
70449704645
-
Autophagy inhibition through PI3K/Akt increases apoptosis by sodium selenite in NB4 cells
-
Ren Y, Huang F, Liu Y, Yang Y, Jiang Q and Xu C: Autophagy inhibition through PI3K/Akt increases apoptosis by sodium selenite in NB4 cells. BMB Rep 42: 599-604, 2009.
-
(2009)
BMB Rep
, vol.42
, pp. 599-604
-
-
Ren, Y.1
Huang, F.2
Liu, Y.3
Yang, Y.4
Jiang, Q.5
Xu, C.6
-
17
-
-
0033978633
-
Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pa7thways that control macroautophagy in HT-29 cells
-
DOI 10.1074/jbc.275.2.992
-
Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ and Codogno P: Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 275: 992-998, 2000. (Pubitemid 30051145)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.2
, pp. 992-998
-
-
Petiot, A.1
Ogier-Denis, E.2
Blommaart, E.F.C.3
Meijer, A.J.4
Codogno, P.5
-
18
-
-
0035335505
-
Novel cell lines established from a human myxoid malignant fibrous histiocytoma arising in the uterus
-
DOI 10.1016/S0165-4608(00)00413-1, PII S0165460800004131
-
Kiyozuka Y, Nakagawa H, Uemura Y, et al.: Novel cell lines established from a human myxoid malignant fibrous histiocytoma arising in the uterus. Cancer Genet Cytogenet 127: 7-15, 2001. (Pubitemid 32530087)
-
(2001)
Cancer Genetics and Cytogenetics
, vol.127
, Issue.1
, pp. 7-15
-
-
Kiyozuka, Y.1
Nakagawa, H.2
Uemura, Y.3
Senzaki, H.4
Yamamoto, A.5
Noguchi, T.6
Mizuta, H.7
Nakanishi, K.8
Nakano, S.9
Tsubura, A.10
-
19
-
-
0028836002
-
Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles
-
Biederbick A, Kern HF and Elsasser HP: Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol 66: 3-14, 1995.
-
(1995)
Eur J Cell Biol
, vol.66
, pp. 3-14
-
-
Biederbick, A.1
Kern, H.F.2
Elsasser, H.P.3
-
20
-
-
34548442360
-
Mechanisms of mammalian target of rapamycin inhibition in sarcoma: Present and future
-
DOI 10.1586/14737140.7.8.1145
-
MacKenzie AR and von Mehren M: Mechanisms of mammalian target of rapamycin inhibition in sarcoma: present and future. Expert Rev Anticancer Ther 7: 1145-1154, 2007. (Pubitemid 47365007)
-
(2007)
Expert Review of Anticancer Therapy
, vol.7
, Issue.8
, pp. 1145-1154
-
-
MacKenzie, A.R.1
Von, M.M.2
-
21
-
-
34548700597
-
Rapamycin: Something old, something new, sometimes borrowed and now renewed
-
DOI 10.1038/sj.clpt.6100317, PII 6100317
-
Hartford CM and Ratain MJ: Rapamycin: something old, something new, sometimes borrowed and now renewed. Clin Pharmacol Ther 82: 381-388, 2007. (Pubitemid 47414349)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.82
, Issue.4
, pp. 381-388
-
-
Hartford, C.M.1
Ratain, M.J.2
-
23
-
-
36849029088
-
Temsirolimus
-
DOI 10.1358/dot.2007.43.10.1148059
-
Ma WW and Jimeno A: Temsirolimus. Drugs Today 43: 659-669, 2007. (Pubitemid 350220790)
-
(2007)
Drugs of Today
, vol.43
, Issue.10
, pp. 659-669
-
-
Ma, W.W.1
Jimeno, A.2
-
24
-
-
34248647440
-
Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma
-
DOI 10.2353/ajpath.2006.051078
-
Peponi E, Drakos E, Reyes G, Leventaki V, Rassidakis GZ and Medeiros LJ: Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma. Am J Pathol 169: 2171-2180, 2006. (Pubitemid 351181976)
-
(2006)
American Journal of Pathology
, vol.169
, Issue.6
, pp. 2171-2180
-
-
Peponi, E.1
Drakos, E.2
Reyes, G.3
Leventaki, V.4
Rassidakis, G.Z.5
Medeiros, L.J.6
-
25
-
-
53749093224
-
Mechanisms of disease: Survival benefit of temsirolimus validates a role for mTOR in the management of advanced RCC
-
Figlin RA: Mechanisms of disease: survival benefit of temsirolimus validates a role for mTOR in the management of advanced RCC. Nat Clin Pract Oncol 5: 601-609, 2008.
-
(2008)
Nat Clin Pract Oncol
, vol.5
, pp. 601-609
-
-
Figlin, R.A.1
-
26
-
-
42949133285
-
Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo
-
DOI 10.1038/sj.onc.1210938, PII 1210938
-
Johnsen JI, Segerstrom L, Orrego A, et al.: Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo. Oncogene 27: 2910-2922, 2008. (Pubitemid 351620441)
-
(2008)
Oncogene
, vol.27
, Issue.20
, pp. 2910-2922
-
-
Johnsen, J.I.1
Segerstrom, L.2
Orrego, A.3
Elfman, L.4
Henriksson, M.5
Kagedal, B.6
Eksborg, S.7
Sveinbjornsson, B.8
Kogner, P.9
-
27
-
-
0038094504
-
Cip1
-
DOI 10.1016/S1097-2765(03)00180-1
-
Huang S, Shu L, Dilling MB, et al.: Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1). Mol Cell 11: 1491-1501, 2003. (Pubitemid 36776536)
-
(2003)
Molecular Cell
, vol.11
, Issue.6
, pp. 1491-1501
-
-
Huang, S.1
Shu, L.2
Dilling, M.B.3
Easton, J.4
Harwood, F.C.5
Ichijo, H.6
Houghton, P.J.7
-
28
-
-
40749094917
-
Temsirolimus downregulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma
-
DOI 10.1016/j.exphem.2007.12.008, PII S0301472X07007059
-
Yazbeck VY, Buglio D, Georgakis GV, et al.: Temsirolimus down-regulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma. Exp Hematol 36: 443-450, 2008. (Pubitemid 351384743)
-
(2008)
Experimental Hematology
, vol.36
, Issue.4
, pp. 443-450
-
-
Yazbeck, V.Y.1
Buglio, D.2
Georgakis, G.V.3
Li, Y.4
Iwado, E.5
Romaguera, J.E.6
Kondo, S.7
Younes, A.8
-
29
-
-
77149128638
-
Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells
-
Nishikawa T, Tsuno NH, Okaji Y, et al.: Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells. Ann Surg Oncol 17: 592-602, 2010.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 592-602
-
-
Nishikawa, T.1
Tsuno, N.H.2
Okaji, Y.3
-
30
-
-
65449118437
-
LC3-I conversion to LC3-II does not necessarily result in complete autophagy
-
Gimenez-Xavier P, Francisco R, Platini F, Perez R and Ambrosio S: LC3-I conversion to LC3-II does not necessarily result in complete autophagy. Int J Mol Med 22: 781-785, 2008.
-
(2008)
Int J Mol Med
, vol.22
, pp. 781-785
-
-
Gimenez-Xavier, P.1
Francisco, R.2
Platini, F.3
Perez, R.4
Ambrosio, S.5
-
31
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
DOI 10.1126/science.290.5497.1717
-
Klionsky DJ and Emr SD: Autophagy as a regulated pathway of cellular degradation. Science 290: 1717-1721, 2000. (Pubitemid 32004796)
-
(2000)
Science
, vol.290
, Issue.5497
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
|