메뉴 건너뛰기




Volumn 19, Issue 1, 2016, Pages 39-52

Targeting VEGF-A with a vaccine decreases inflammation and joint destruction in experimental arthritis

Author keywords

Arthritis; Inflammation; Peptides; Vaccines; VEGF

Indexed keywords

COLLAGEN ANTIBODY; KEYHOLE LIMPET HEMOCYANIN; PEPTIDE VACCINE; TYPE II COLLAGEN ANTIBODY; UNCLASSIFIED DRUG; VACCINE; VASCULOTROPIN A; VASCULOTROPIN ANTIBODY; VASCULOTROPIN RECEPTOR 2; VEGF K PEPTIDE; VPEP1 K PEPTIDE; VPEP2 K PEPTIDE; PEPTIDE;

EID: 84952982472     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-015-9487-0     Document Type: Article
Times cited : (21)

References (52)
  • 1
    • 0033577525 scopus 로고    scopus 로고
    • Angioneogenesis as a possible elusive triggering factor in rheumatoid arthritis
    • PID: 10218539
    • Hirohata S, Sakakibara J (1999) Angioneogenesis as a possible elusive triggering factor in rheumatoid arthritis. Lancet 353:1331
    • (1999) Lancet , vol.353 , pp. 1331
    • Hirohata, S.1    Sakakibara, J.2
  • 2
    • 0028934327 scopus 로고
    • Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism
    • PID: 7533784
    • Mansson B, Carey D, Alini M et al (1995) Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism. J Clin Invest 95:1071–1077
    • (1995) J Clin Invest , vol.95 , pp. 1071-1077
    • Mansson, B.1    Carey, D.2    Alini, M.3
  • 3
    • 0026091413 scopus 로고
    • Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis
    • PID: 1930331
    • Chu CQ, Field M, Feldmann M, Maini RN (1991) Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum 34:1125–1132
    • (1991) Arthritis Rheum , vol.34 , pp. 1125-1132
    • Chu, C.Q.1    Field, M.2    Feldmann, M.3    Maini, R.N.4
  • 4
    • 0027518860 scopus 로고
    • Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity
    • PID: 8484679
    • Madhok R, Crilly A, Watson J, Capell HA (1993) Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity. Ann Rheum Dis 52:232–234
    • (1993) Ann Rheum Dis , vol.52 , pp. 232-234
    • Madhok, R.1    Crilly, A.2    Watson, J.3    Capell, H.A.4
  • 5
    • 0037333960 scopus 로고    scopus 로고
    • Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy
    • PID: 12632409
    • Miossec P (2003) Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy. Arthritis Rheum 48:594–601
    • (2003) Arthritis Rheum , vol.48 , pp. 594-601
    • Miossec, P.1
  • 6
    • 79952248595 scopus 로고    scopus 로고
    • Blood vessels, a potential therapeutic target in rheumatoid arthritis?
    • PID: 20851025
    • Semerano L, Clavel G, Assier E, Denys A, Boissier MC (2011) Blood vessels, a potential therapeutic target in rheumatoid arthritis? Joint Bone Spine 78:118–123
    • (2011) Joint Bone Spine , vol.78 , pp. 118-123
    • Semerano, L.1    Clavel, G.2    Assier, E.3    Denys, A.4    Boissier, M.C.5
  • 7
    • 79953680176 scopus 로고    scopus 로고
    • Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structural joint damage at one year
    • PID: 21360490
    • Kremer JM, Blanco R, Brzosko M et al (2011) Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structural joint damage at one year. Arthritis Rheum 63:609–621
    • (2011) Arthritis Rheum , vol.63 , pp. 609-621
    • Kremer, J.M.1    Blanco, R.2    Brzosko, M.3
  • 8
    • 34047141776 scopus 로고    scopus 로고
    • Vascular endothelial growth factor family of ligands and receptors: review
    • PID: 17344076
    • Otrock ZK, Makarem JA, Shamseddine AI (2007) Vascular endothelial growth factor family of ligands and receptors: review. Blood Cells Mol Dis 38:258–268
    • (2007) Blood Cells Mol Dis , vol.38 , pp. 258-268
    • Otrock, Z.K.1    Makarem, J.A.2    Shamseddine, A.I.3
  • 9
    • 34447310236 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis
    • PID: 17109193
    • Shibuya M (2006) Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis. Angiogenesis 9:225
    • (2006) Angiogenesis , vol.9 , pp. 225
    • Shibuya, M.1
  • 10
    • 35348925095 scopus 로고    scopus 로고
    • Relationship between angiogenesis and inflammation in experimental arthritis
    • PID: 17194641
    • Clavel G, Valvason C, Yamaoka K et al (2006) Relationship between angiogenesis and inflammation in experimental arthritis. Eur Cytokine Netw 17:202
    • (2006) Eur Cytokine Netw , vol.17 , pp. 202
    • Clavel, G.1    Valvason, C.2    Yamaoka, K.3
  • 11
    • 56749183250 scopus 로고    scopus 로고
    • Ultrasound and Doppler micro-imaging in a model of rheumatoid arthritis in mice
    • PID: 18218664
    • Clavel G, Marchiol-Fournigault C, Renault G et al (2008) Ultrasound and Doppler micro-imaging in a model of rheumatoid arthritis in mice. Ann Rheum Dis 67:1765–1772
    • (2008) Ann Rheum Dis , vol.67 , pp. 1765-1772
    • Clavel, G.1    Marchiol-Fournigault, C.2    Renault, G.3
  • 12
    • 0034114929 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression and regulation of murine collagen-induced arthritis
    • PID: 10820274
    • Lu J, Kasama T, Kobayashi K et al (2000) Vascular endothelial growth factor expression and regulation of murine collagen-induced arthritis. J Immunol 164:5922–5927
    • (2000) J Immunol , vol.164 , pp. 5922-5927
    • Lu, J.1    Kasama, T.2    Kobayashi, K.3
  • 13
    • 10744228170 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor receptor I (VEGF-RI), but not VEGF-RII, suppresses joint destruction in the K/BxN model of rheumatoid arthritis
    • PID: 14568965
    • De Bandt M, Ben Mahdi MH, Ollivier V et al (2003) Blockade of vascular endothelial growth factor receptor I (VEGF-RI), but not VEGF-RII, suppresses joint destruction in the K/BxN model of rheumatoid arthritis. J Immunol 171:4853–4859
    • (2003) J Immunol , vol.171 , pp. 4853-4859
    • De Bandt, M.1    Ben Mahdi, M.H.2    Ollivier, V.3
  • 14
    • 33845879373 scopus 로고    scopus 로고
    • TNFalpha kinoid vaccination-induced neutralizing antibodies to TNFalpha protect mice from autologous TNFalpha-driven chronic and acute inflammation
    • PID: 17158801
    • Le Buanec H, Delavallée L, Bessis N et al (2006) TNFalpha kinoid vaccination-induced neutralizing antibodies to TNFalpha protect mice from autologous TNFalpha-driven chronic and acute inflammation. Proc Natl Acad Sci USA 103:19442–19447
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 19442-19447
    • Le Buanec, H.1    Delavallée, L.2    Bessis, N.3
  • 15
    • 50249187809 scopus 로고    scopus 로고
    • Early and long-lasting protection from arthritis in tumour necrosis factor alpha (TNFalpha) transgenic mice vaccinated against TNFalpha
    • PID: 18042641
    • Delavallée L, Le Buanec H, Bessis N et al (2008) Early and long-lasting protection from arthritis in tumour necrosis factor alpha (TNFalpha) transgenic mice vaccinated against TNFalpha. Ann Rheum Dis 67:1332–1338
    • (2008) Ann Rheum Dis , vol.67 , pp. 1332-1338
    • Delavallée, L.1    Le Buanec, H.2    Bessis, N.3
  • 16
    • 84874979868 scopus 로고    scopus 로고
    • Protection from articular damage by passive or active anti-tumour necrosis factor (TNF)-α immunotherapy in human TNF-α transgenic mice depends on anti-TNF-α antibody levels
    • PID: 23480185
    • Semerano L, Biton J, Delavallée L et al (2013) Protection from articular damage by passive or active anti-tumour necrosis factor (TNF)-α immunotherapy in human TNF-α transgenic mice depends on anti-TNF-α antibody levels. Clin Exp Immunol 172:54–62
    • (2013) Clin Exp Immunol , vol.172 , pp. 54-62
    • Semerano, L.1    Biton, J.2    Delavallée, L.3
  • 17
    • 84872777792 scopus 로고    scopus 로고
    • The impact of Bevacizumab (Avastin) on survival in metastatic solid tumors–a meta-analysis and systematic review
    • PID: 23349675
    • Amit L, Ben-Aharon I, Vidal L, Leibovici L, Stemmer SM (2013) The impact of Bevacizumab (Avastin) on survival in metastatic solid tumors–a meta-analysis and systematic review. PLoS One 8:e51780
    • (2013) PLoS One , vol.8 , pp. e51780
    • Amit, L.1    Ben-Aharon, I.2    Vidal, L.3    Leibovici, L.4    Stemmer, S.M.5
  • 18
    • 33847326301 scopus 로고    scopus 로고
    • VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases
    • PID: 17301234
    • Rad FH, Le Buanec H, Paturance S et al (2007) VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases. Proc Natl Acad Sci USA 104:2837–2842
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 2837-2842
    • Rad, F.H.1    Le Buanec, H.2    Paturance, S.3
  • 19
    • 0031572858 scopus 로고    scopus 로고
    • The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: multiple copy flexibility and receptor binding
    • PID: 9351807
    • Muller YA, Christinger HW, Keyt BA, de Vos AM (1997) The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: multiple copy flexibility and receptor binding. Structure 5:1325–1328
    • (1997) Structure , vol.5 , pp. 1325-1328
    • Muller, Y.A.1    Christinger, H.W.2    Keyt, B.A.3    de Vos, A.M.4
  • 20
    • 74849095453 scopus 로고    scopus 로고
    • Anti-neuropilin-1 peptide inhibition of synoviocyte survival, angiogenesis, and experimental arthritis
    • PID: 20039409
    • Kong JS, Yoo SA, Kim JW et al (2010) Anti-neuropilin-1 peptide inhibition of synoviocyte survival, angiogenesis, and experimental arthritis. Arthritis Rheum 62:179
    • (2010) Arthritis Rheum , vol.62 , pp. 179
    • Kong, J.S.1    Yoo, S.A.2    Kim, J.W.3
  • 21
    • 33751091501 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1
    • PID: 16959272
    • Starzec A, Vassy R, Martin A et al (2006) Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1. Life Sci 79:2370–2371
    • (2006) Life Sci , vol.79 , pp. 2370-2371
    • Starzec, A.1    Vassy, R.2    Martin, A.3
  • 22
    • 0035853679 scopus 로고    scopus 로고
    • The crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolution
    • PID: 11069911
    • Iyer S, Leonidas DD, Swaminathan GJ et al (2001) The crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolution. J Biol Chem 276:12153–12161
    • (2001) J Biol Chem , vol.276 , pp. 12153-12161
    • Iyer, S.1    Leonidas, D.D.2    Swaminathan, G.J.3
  • 23
    • 84859488831 scopus 로고    scopus 로고
    • Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1
    • PID: 22318724
    • Parker MW, Xu P, Li X, Vander Kooi CW (2012) Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1. J Biol Chem 287:11082–11089
    • (2012) J Biol Chem , vol.287 , pp. 11082-11089
    • Parker, M.W.1    Xu, P.2    Li, X.3    Vander Kooi, C.W.4
  • 24
    • 0031438075 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial cell proliferation by a peptide corresponding to the exon 7-encoded domain of VEGF165
    • PID: 9395496
    • Soker S, Gollamudi-Payne S, Fidder H, Charmahelli H, Klagsbrun M (1997) Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial cell proliferation by a peptide corresponding to the exon 7-encoded domain of VEGF165. J Biol Chem 272:31582–31588
    • (1997) J Biol Chem , vol.272 , pp. 31582-31588
    • Soker, S.1    Gollamudi-Payne, S.2    Fidder, H.3    Charmahelli, H.4    Klagsbrun, M.5
  • 25
    • 29744438008 scopus 로고    scopus 로고
    • Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway
    • PID: 16304639
    • Miellot A, Zhu R, Diem S et al (2005) Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway. Eur J Immunol 35:3704–3713
    • (2005) Eur J Immunol , vol.35 , pp. 3704-3713
    • Miellot, A.1    Zhu, R.2    Diem, S.3
  • 26
    • 33748703844 scopus 로고    scopus 로고
    • Signaling of vascular endothelial growth factor receptor-1 tyrosine kinase promotes rheumatoid arthritis through activation of monocytes/macrophages
    • PID: 16709927
    • Murakami M, Iwai S, Hiratsuka S et al (2006) Signaling of vascular endothelial growth factor receptor-1 tyrosine kinase promotes rheumatoid arthritis through activation of monocytes/macrophages. Blood 108:1849–1856
    • (2006) Blood , vol.108 , pp. 1849-1856
    • Murakami, M.1    Iwai, S.2    Hiratsuka, S.3
  • 27
    • 77957727112 scopus 로고    scopus 로고
    • TGF-beta1 induces mouse dendritic cells to express VEGF and its receptor (Flt-1) under hypoxic conditions
    • PID: 20631490
    • Nam EH, Park SR, Kim PH (2010) TGF-beta1 induces mouse dendritic cells to express VEGF and its receptor (Flt-1) under hypoxic conditions. Exp Mol Med 42:606–613
    • (2010) Exp Mol Med , vol.42 , pp. 606-613
    • Nam, E.H.1    Park, S.R.2    Kim, P.H.3
  • 28
    • 33749518527 scopus 로고    scopus 로고
    • Interaction of vascular endothelial growth factor 165 with neuropilin-1 protects rheumatoid synoviocytes from apoptotic death by regulating Bcl-2 expression and Bax translocation
    • PID: 17015762
    • Kim WU, Kang SS, Yoo SA et al (2006) Interaction of vascular endothelial growth factor 165 with neuropilin-1 protects rheumatoid synoviocytes from apoptotic death by regulating Bcl-2 expression and Bax translocation. J Immunol 177:5727–5735
    • (2006) J Immunol , vol.177 , pp. 5727-5735
    • Kim, W.U.1    Kang, S.S.2    Yoo, S.A.3
  • 29
    • 84885751156 scopus 로고    scopus 로고
    • VEGFA/VEGFR2-targeted therapies prevent the VEGFA-induced proliferation of regulatory T cells in cancer
    • PID: 24083078
    • Terme M, Tartour E, Taieb J (2013) VEGFA/VEGFR2-targeted therapies prevent the VEGFA-induced proliferation of regulatory T cells in cancer. Oncoimmunology 2:e25156
    • (2013) Oncoimmunology , vol.2 , pp. e25156
    • Terme, M.1    Tartour, E.2    Taieb, J.3
  • 30
    • 84869777544 scopus 로고    scopus 로고
    • Neuropilin 1 deficiency on CD4 + Foxp3 + regulatory T cells impairs mouse melanoma growth
    • Hansen W, Hutzler M, Abel S et al (2013) Neuropilin 1 deficiency on CD4 + Foxp3 + regulatory T cells impairs mouse melanoma growth. J Exp Med 209:2001–2006
    • (2013) J Exp Med , vol.209 , pp. 2001-2006
    • Hansen, W.1    Hutzler, M.2    Abel, S.3
  • 31
    • 84872593848 scopus 로고    scopus 로고
    • VEGFA-VEGFR pathway blockade inhibits tumor-induced regulatory T-cell proliferation in colorectal cancer
    • Terme M, Pernot S, Marcheteau E et al (2013) VEGFA-VEGFR pathway blockade inhibits tumor-induced regulatory T-cell proliferation in colorectal cancer. Cancer Res 73:539–539
    • (2013) Cancer Res , vol.73 , pp. 539
    • Terme, M.1    Pernot, S.2    Marcheteau, E.3
  • 32
    • 58249136903 scopus 로고    scopus 로고
    • Regulatory T cells (Treg) in rheumatoid arthritis
    • PID: 19028128
    • Boissier MC, Assier E, Biton J et al (2009) Regulatory T cells (Treg) in rheumatoid arthritis. Joint Bone Spine 76:10–14
    • (2009) Joint Bone Spine , vol.76 , pp. 10-14
    • Boissier, M.C.1    Assier, E.2    Biton, J.3
  • 33
    • 33846446041 scopus 로고    scopus 로고
    • Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta
    • PID: 17200409
    • Nadkarni S, Mauri C, Ehrenstein MR (2007) Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta. J Exp Med 204:33–39
    • (2007) J Exp Med , vol.204 , pp. 33-39
    • Nadkarni, S.1    Mauri, C.2    Ehrenstein, M.R.3
  • 34
    • 79953656530 scopus 로고    scopus 로고
    • Interplay between TNF and regulatory T cells in a TNF-driven murine model of arthritis
    • PID: 21346237
    • Biton J, Semerano L, Delavallée L et al (2011) Interplay between TNF and regulatory T cells in a TNF-driven murine model of arthritis. J Immunol 186:3899
    • (2011) J Immunol , vol.186 , pp. 3899
    • Biton, J.1    Semerano, L.2    Delavallée, L.3
  • 35
    • 84857800767 scopus 로고    scopus 로고
    • TNFα: activator or inhibitor of regulatory T cells?
    • PID: 22209316
    • Biton J, Boissier MC, Bessis N (2012) TNFα: activator or inhibitor of regulatory T cells? Joint Bone Spine 79:119–123
    • (2012) Joint Bone Spine , vol.79 , pp. 119-123
    • Biton, J.1    Boissier, M.C.2    Bessis, N.3
  • 36
    • 84875153425 scopus 로고    scopus 로고
    • Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis
    • PID: 23396208
    • Nie H, Zheng Y, Li R et al (2013) Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis. Nat Med 19:322–328
    • (2013) Nat Med , vol.19 , pp. 322-328
    • Nie, H.1    Zheng, Y.2    Li, R.3
  • 37
    • 84896262403 scopus 로고    scopus 로고
    • Interleukin-6 receptor blockade enhances CD39 + regulatory T cell development in rheumatoid arthritis and in experimental arthritis
    • PID: 24504799
    • Thiolat A, Semerano L, Pers YM et al (2014) Interleukin-6 receptor blockade enhances CD39 + regulatory T cell development in rheumatoid arthritis and in experimental arthritis. Arthritis Rheumatol 66:273–283
    • (2014) Arthritis Rheumatol , vol.66 , pp. 273-283
    • Thiolat, A.1    Semerano, L.2    Pers, Y.M.3
  • 38
    • 84855161152 scopus 로고    scopus 로고
    • Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis
    • PID: 21976387
    • Cortes J, Calvo V, Ramirez-Merino N et al (2012) Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis. Ann Oncol 23:1130–1137
    • (2012) Ann Oncol , vol.23 , pp. 1130-1137
    • Cortes, J.1    Calvo, V.2    Ramirez-Merino, N.3
  • 39
    • 0034940764 scopus 로고    scopus 로고
    • Toward a new generation of vaccines: the anti-cytokine therapeutic vaccines
    • PID: 11438746
    • Zagury D, Burny A, Gallo RC (2001) Toward a new generation of vaccines: the anti-cytokine therapeutic vaccines. Proc Natl Acad Sci USA 98:8024–8029
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8024-8029
    • Zagury, D.1    Burny, A.2    Gallo, R.C.3
  • 40
    • 22144457874 scopus 로고    scopus 로고
    • Improvement of collagen-induced arthritis by active immunization against murine IL-1beta peptides designed by molecular modelling
    • PID: 16005738
    • Bertin-Maghit SM, Capini CJ, Bessis N et al (2005) Improvement of collagen-induced arthritis by active immunization against murine IL-1beta peptides designed by molecular modelling. Vaccine 23:4228–4235
    • (2005) Vaccine , vol.23 , pp. 4228-4235
    • Bertin-Maghit, S.M.1    Capini, C.J.2    Bessis, N.3
  • 41
    • 3843101609 scopus 로고    scopus 로고
    • Active immunization against murine TNFalpha peptides in mice: generation of endogenous antibodies cross-reacting with the native cytokine and in vivo protection
    • PID: 15297067
    • Capini CJ, Bertin-Maghit SM, Bessis N et al (2004) Active immunization against murine TNFalpha peptides in mice: generation of endogenous antibodies cross-reacting with the native cytokine and in vivo protection. Vaccine 22:3144–3153
    • (2004) Vaccine , vol.22 , pp. 3144-3153
    • Capini, C.J.1    Bertin-Maghit, S.M.2    Bessis, N.3
  • 42
    • 80855131595 scopus 로고    scopus 로고
    • Active immunization against IL-23p19 improves experimental arthritis
    • PID: 22008816
    • Ratsimandresy RA, Duvallet E, Assier E et al (2011) Active immunization against IL-23p19 improves experimental arthritis. Vaccine 29:9329–9336
    • (2011) Vaccine , vol.29 , pp. 9329-9336
    • Ratsimandresy, R.A.1    Duvallet, E.2    Assier, E.3
  • 43
    • 84887010556 scopus 로고    scopus 로고
    • Double-antiangiogenic protein DAAP targeting vascular endothelial growth factor A and angiopoietins attenuates collagen-induced arthritis
    • PID: 23945080
    • Hah YS, Koh YJ, Lim HS et al (2013) Double-antiangiogenic protein DAAP targeting vascular endothelial growth factor A and angiopoietins attenuates collagen-induced arthritis. Arthritis Res Ther 15:R85
    • (2013) Arthritis Res Ther , vol.15 , pp. R85
    • Hah, Y.S.1    Koh, Y.J.2    Lim, H.S.3
  • 44
    • 0026644298 scopus 로고
    • Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
    • PID: 1409699
    • Williams RO, Feldmann M, Maini RN (1992) Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci USA 89:9784
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9784
    • Williams, R.O.1    Feldmann, M.2    Maini, R.N.3
  • 45
    • 8444236292 scopus 로고    scopus 로고
    • TNF-a antibodies and osteoprotegerin decrease systemic bone loss associated with inflammation through distinct mechanisms in collagen-induced arthritis
    • PID: 15542046
    • Saidenberg-Kermanac’h N, Corrado A, Lemeiter D et al (2004) TNF-a antibodies and osteoprotegerin decrease systemic bone loss associated with inflammation through distinct mechanisms in collagen-induced arthritis. Bone 35:1200–1207
    • (2004) Bone , vol.35 , pp. 1200-1207
    • Saidenberg-Kermanac’h, N.1    Corrado, A.2    Lemeiter, D.3
  • 46
    • 84888200948 scopus 로고    scopus 로고
    • Avastin exhibits therapeutic effects on collagen-induced arthritis in rat model
    • PID: 23851616
    • Wang Y, Da G, Li H et al (2013) Avastin exhibits therapeutic effects on collagen-induced arthritis in rat model. Inflammation 36:1460–1467
    • (2013) Inflammation , vol.36 , pp. 1460-1467
    • Wang, Y.1    Da, G.2    Li, H.3
  • 47
    • 77956933050 scopus 로고    scopus 로고
    • Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair
    • PID: 20868495
    • Nagai T, Sato M, Kutsuna T et al (2010) Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair. Arthritis Res Ther 12:R178
    • (2010) Arthritis Res Ther , vol.12 , pp. R178
    • Nagai, T.1    Sato, M.2    Kutsuna, T.3
  • 48
    • 40649128599 scopus 로고    scopus 로고
    • Interaction between bevacizumab and murine VEGF-A: a reassessment
    • PID: 18234994
    • Yu L, Wu X, Cheng Z et al (2008) Interaction between bevacizumab and murine VEGF-A: a reassessment. Invest Ophthalmol Vis Sci 49:522–527
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 522-527
    • Yu, L.1    Wu, X.2    Cheng, Z.3
  • 49
    • 59749103950 scopus 로고    scopus 로고
    • Therapeutic effect of anti-vascular endothelial growth factor receptor I antibody in the established collagen-induced arthritis mouse model
    • PID: 19101756
    • Choi ST, Kim JH, Seok JY et al (2009) Therapeutic effect of anti-vascular endothelial growth factor receptor I antibody in the established collagen-induced arthritis mouse model. Clin Rheumatol 28:333–337
    • (2009) Clin Rheumatol , vol.28 , pp. 333-337
    • Choi, S.T.1    Kim, J.H.2    Seok, J.Y.3
  • 50
    • 17844372767 scopus 로고    scopus 로고
    • Arginine-rich anti-vascular endothelial growth factor (anti-VEGF) hexapeptide inhibits collagen-induced arthritis and VEGF-stimulated productions of TNF-alpha and IL-6 by human monocytes
    • PID: 15843589
    • Yoo SA, Bae DG, Ryoo JW et al (2005) Arginine-rich anti-vascular endothelial growth factor (anti-VEGF) hexapeptide inhibits collagen-induced arthritis and VEGF-stimulated productions of TNF-alpha and IL-6 by human monocytes. J Immunol 174:5846–5855
    • (2005) J Immunol , vol.174 , pp. 5846-5855
    • Yoo, S.A.1    Bae, D.G.2    Ryoo, J.W.3
  • 51
    • 77952514447 scopus 로고    scopus 로고
    • Active immunization to tumor necrosis factor-alpha is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis
    • PID: 20030816
    • Delavallée L, Semerano L, Assier E et al (2009) Active immunization to tumor necrosis factor-alpha is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis. Arthritis Res Ther 11:R195
    • (2009) Arthritis Res Ther , vol.11 , pp. R195
    • Delavallée, L.1    Semerano, L.2    Assier, E.3
  • 52
    • 84919467063 scopus 로고    scopus 로고
    • Therapeutic vaccination with TNF-kinoid in TNF antagonist-resistant rheumatoid arthritis: a phase II randomized, controlled clinical trial
    • PID: 25517733
    • Durez P, Vandepapeliere P, Miranda P et al (2014) Therapeutic vaccination with TNF-kinoid in TNF antagonist-resistant rheumatoid arthritis: a phase II randomized, controlled clinical trial. PLoS One 9:e113465
    • (2014) PLoS One , vol.9 , pp. e113465
    • Durez, P.1    Vandepapeliere, P.2    Miranda, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.