Avastin exhibits therapeutic effects on collagen-induced arthritis in rat model

Inflammation

Volumn 36, Issue 6, 2013, Pages 1460-1467

  Wang, Yong ^a,b   Da, Gula ^b   Li, Hongbin ^b   Zheng, Yi ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b AFFILIATED HOSPITAL OF INNER MONGOLIA MEDICAL UNIVERSITY   (China)

Author keywords

avastin; collagen induced arthritis; rheumatoid arthritis; vascular endothelial growth factor

Indexed keywords

BEVACIZUMAB; COLLAGEN TYPE 2; ETANERCEPT; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; FOOT PAD; IMMUNOHISTOCHEMISTRY; JOINT SWELLING; NONHUMAN; PATHOLOGY; RAT; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

RATTUS; RATTUS NORVEGICUS;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODIES, MONOCLONAL, HUMANIZED; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; COLLAGEN; FEMALE; IMMUNOGLOBULIN G; JOINTS; RATS; RATS, WISTAR; RECEPTORS, TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84888200948     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-013-9687-y     Document Type: Article

References (19)

1. Konisti, S., S. Kiriakidis, and E.M. Paleolog. 2012. Hypoxia - a key regulator of angiogenesis and inflammation in rheumatoid arthritis. Nat Rev Rheumatol 8: 153-162.
2. Szekanecz, Z., T. Besenyei, G. Paragh, et al. 2009. Angiogenesis in rheumatoid arthritis. Autoimmunity 42: 563-573.
3. Szekanecz, Z., and A.E. Koch. 2008. Targeting angiogenesis in rheumatoid arthritis. Curr Rheumatol Rev 4: 298-303.
4. Aaltonen, K.J., L.M. Virkki, A. Malmivaara, et al. 2012. Systematic review and meta-analysis of the efficacy and safety of existing TNF blocking agents in treatment of rheumatoid arthritis. PLoS One 7: e30275.
5. Alonso-Ruiz, A., J.I. Pijoan, E. Ansuategui, A. Urkaregi, M. Calabozo, and A. Quintana. 2008. Tumor necrosis factor alpha drugs in rheumatoid arthritis: systematic review and metaanalysis of efficacy and safety. BMC Musculoskelet Disord 9: 52.
6. Heinzerling, J.H., and S. Huerta. 2006. Bowel perforation from bevacizumab for the treatment of metastatic colon cancer: incidence, etiology, and management. Curr Surg 63: 334-337.
7. Luo, X., X. Zuo, X. Mo, Y. Zhou, and X. Xiao. 2011. Treatment with recombinant Hsp72 suppresses collagen-induced arthritis in mice. Inflammation 34: 432-439.
8. Palmblad, K., H. Erlandsson-Harris, K.J. Tracey, et al. 2001. Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis: a therapeutic study using a macrophage-deactivating compound. Am J Pathol 158: 491-500.
9. Romas, E., N.A. Sims, D.K. Hards, et al. 2002. Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis. Am J Pathol 161: 1419-1427.
10. Yoo, S.A., S.K. Kwok, and W.U. Kim. 2008. Proinflammatory role of vascular endothelial growth factor in the pathogenesis of rheumatoid arthritis: prospects for therapeutic intervention. Mediat Inflamm 2008: 129873.
11. Paleolog, E.M. 2009. The vasculature in rheumatoid arthritis: cause or consequence? Int J Exp Pathol 90: 249-261.
12. Szekanecz, Z., T. Besenyei, A. Szentpétery, and A.E. Koch. 2010. Angiogenesis and vasculogenesis in rheumatoid arthritis. Curr Opin Rheumatol 22: 299-306.
13. Nagashima, M., H. Tanaka, H. Takahashi, et al. 2002. Study of the mechanism involved in angiogenesis and synovial cell proliferation in human synovial tissues of patients with rheumatoid arthritis using SCID mice. Lab Invest 82: 981-988.
14. Hashimoto, A., I.H. Tarner, R.M. Bohle, et al. 2007. Analysis of vascular gene expression in arthritic synovium by laser-mediated microdissection. Arthritis Rheum 56: 1094-105.
15. Clavel, G., N. Bessis, D. Lemeiter, et al. 2007. Angiogenesis markers (VEGF, soluble receptor of VEGF and angiopoietin-1) in very early arthritis and their association with inflammation and joint destruction. Clin Immunol 124: 158-164.
16. Thairu, N., S. Kiriakidis, P. Dawson, et al. 2011. Angiogenesis as a therapeutic target in arthritis in 2011: learning the lessons of the colorectal cancer experience. Angiogenesis 14: 223-234.
17. van Luijn, J.C., M. Danz, J.W. Bijlsma, F.W. Gribnau, and H.G. Leufkens. 2011. Post-approval trials of new medicines: widening use or deepening knowledge? Analysis of 10 years of Etanercept. Scand J Rheumatol 40: 183-191.
18. Cha, H.S., E.K. Bae, J.H. Koh, et al. 2007. Tumor necrosis factor-alpha induces vascular endothelial growth factor-C expression in rheumatoid synoviocytes. J Rheumatol 34: 16-19.
19. Su, Z.F., G. Liu, S. Gupta, Z. Zhu, M. Rusckowski, and D.J. Hnatowich. 2002. In vitro and in vivo evaluation of a Technetium-99m-labeled cyclic RGD peptide as a specific marker of alpha(V)beta(3) integrin for tumor imaging. Bioconjug Chem 13: 561-570.