Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice with Severe Acute Pancreatitis

Gastroenterology

Volumn 149, Issue 7, 2015, Pages 1920-1931.e8

  Merza, Mohammed ^a   Hartman, Hannes ^a   Rahman, Milladur ^a   Hwaiz, Rundk ^a   Zhang, Enming ^b   Renström, Erik ^b   Luo, Lingtao ^a   Mörgelin, Matthias ^a   Regner, Sara ^a   Thorlacius, Henrik ^a  

^a LUND UNIVERSITY   (Sweden)

^b Department of Clinical Sciences ^*  (Sweden)

Author keywords

Chemokines; Histones; Inflammation; Leukocytes

Indexed keywords

AMYLASE; ARGININE; CD11B ANTIGEN; CXCL2 CHEMOKINE; DEOXYRIBONUCLEASE I; GELATINASE B; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE H3; HISTONE H4; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 2; MYELOPEROXIDASE; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; TAUROCHOLIC ACID; TRYPSIN; AUTACOID; DNA;

ACINAR CELL; ACUTE PANCREATITIS; AMYLASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EXTRACELLULAR TRAP; IN VITRO STUDY; MALE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PANCREAS DUCT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TISSUE INJURY; UPREGULATION; ACUTE DISEASE; ANIMAL; BLOOD; C57BL MOUSE; CASE CONTROL STUDY; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; IMMUNOLOGY; LUNG; METABOLISM; PANCREAS; PANCREATITIS; PATHOLOGY; SEVERITY OF ILLNESS INDEX;

ACUTE DISEASE; ANIMALS; ARGININE; CASE-CONTROL STUDIES; DEOXYRIBONUCLEASE I; DISEASE MODELS, ANIMAL; DNA; ENZYME ACTIVATION; EXTRACELLULAR TRAPS; HUMANS; INFLAMMATION MEDIATORS; LUNG; MALE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; NEUTROPHILS; PANCREAS; PANCREATITIS; SEVERITY OF ILLNESS INDEX; TAUROCHOLIC ACID; TRYPSIN;

EID: 84952910698     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.08.026     Document Type: Article

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