-
1
-
-
57349098220
-
Fibroblast growth factor 21 corrects obesity in mice
-
Coskun T., Bina H.A., Schneider M.A., Dunbar J.D., Hu C.C., Chen Y., Moller D.E., Kharitonenkov A. Fibroblast growth factor 21 corrects obesity in mice. Endocrinology 2008, 149:6018-6027.
-
(2008)
Endocrinology
, vol.149
, pp. 6018-6027
-
-
Coskun, T.1
Bina, H.A.2
Schneider, M.A.3
Dunbar, J.D.4
Hu, C.C.5
Chen, Y.6
Moller, D.E.7
Kharitonenkov, A.8
-
2
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess A.M., Lehman S., Williams G., Tal I., Rodman D., Goldfine A.B., Kuo F.C., Palmer E.L., Tseng Y.H., Doria A., et al. Identification and importance of brown adipose tissue in adult humans. N. Engl. J. Med. 2009, 360:1509-1517.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
Tal, I.4
Rodman, D.5
Goldfine, A.B.6
Kuo, F.C.7
Palmer, E.L.8
Tseng, Y.H.9
Doria, A.10
-
3
-
-
84893849860
-
Interplay between FGF21 and insulin action in the liver regulates metabolism
-
Emanuelli B., Vienberg S.G., Smyth G., Cheng C., Stanford K.I., Arumugam M., Michael M.D., Adams A.C., Kharitonenkov A., Kahn C.R. Interplay between FGF21 and insulin action in the liver regulates metabolism. J. Clin. Invest. 2014, 124:515-527.
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 515-527
-
-
Emanuelli, B.1
Vienberg, S.G.2
Smyth, G.3
Cheng, C.4
Stanford, K.I.5
Arumugam, M.6
Michael, M.D.7
Adams, A.C.8
Kharitonenkov, A.9
Kahn, C.R.10
-
4
-
-
78049297991
-
Obesity is a fibroblast growth factor 21 (FGF21)-resistant state
-
Fisher F.M., Chui P.C., Antonellis P.J., Bina H.A., Kharitonenkov A., Flier J.S., Maratos-Flier E. Obesity is a fibroblast growth factor 21 (FGF21)-resistant state. Diabetes 2010, 59:2781-2789.
-
(2010)
Diabetes
, vol.59
, pp. 2781-2789
-
-
Fisher, F.M.1
Chui, P.C.2
Antonellis, P.J.3
Bina, H.A.4
Kharitonenkov, A.5
Flier, J.S.6
Maratos-Flier, E.7
-
5
-
-
84863012022
-
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
-
Fisher F.M., Kleiner S., Douris N., Fox E.C., Mepani R.J., Verdeguer F., Wu J., Kharitonenkov A., Flier J.S., Maratos-Flier E., Spiegelman B.M. FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis. Genes Dev. 2012, 26:271-281.
-
(2012)
Genes Dev.
, vol.26
, pp. 271-281
-
-
Fisher, F.M.1
Kleiner, S.2
Douris, N.3
Fox, E.C.4
Mepani, R.J.5
Verdeguer, F.6
Wu, J.7
Kharitonenkov, A.8
Flier, J.S.9
Maratos-Flier, E.10
Spiegelman, B.M.11
-
6
-
-
20444435873
-
FGF-21 as a novel metabolic regulator
-
Kharitonenkov A., Shiyanova T.L., Koester A., Ford A.M., Micanovic R., Galbreath E.J., Sandusky G.E., Hammond L.J., Moyers J.S., Owens R.A., et al. FGF-21 as a novel metabolic regulator. J. Clin. Invest. 2005, 115:1627-1635.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1627-1635
-
-
Kharitonenkov, A.1
Shiyanova, T.L.2
Koester, A.3
Ford, A.M.4
Micanovic, R.5
Galbreath, E.J.6
Sandusky, G.E.7
Hammond, L.J.8
Moyers, J.S.9
Owens, R.A.10
-
7
-
-
84921325509
-
Fibroblast growth factor 21 analogue LY2405319 lowers blood glucose in streptozotocin-induced insulin-deficient diabetic mice by restoring brown adipose tissue function
-
Kim J.H., Bae K.H., Choi Y.K., Go Y., Choe M., Jeon Y.H., Lee H.W., Koo S.H., Perfield J.W., Harris R.A., et al. Fibroblast growth factor 21 analogue LY2405319 lowers blood glucose in streptozotocin-induced insulin-deficient diabetic mice by restoring brown adipose tissue function. Diabetes Obes. Metab. 2015, 17:161-169.
-
(2015)
Diabetes Obes. Metab.
, vol.17
, pp. 161-169
-
-
Kim, J.H.1
Bae, K.H.2
Choi, Y.K.3
Go, Y.4
Choe, M.5
Jeon, Y.H.6
Lee, H.W.7
Koo, S.H.8
Perfield, J.W.9
Harris, R.A.10
-
8
-
-
84929708081
-
Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1
-
Samms R.J., Smith D.P., Cheng C.C., Antonellis P.P., Perfield J.W., Kharitonenkov A., Gimeno R.E., Adams A.C. Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1. Cell Rep. 2015, 11:991-999.
-
(2015)
Cell Rep.
, vol.11
, pp. 991-999
-
-
Samms, R.J.1
Smith, D.P.2
Cheng, C.C.3
Antonellis, P.P.4
Perfield, J.W.5
Kharitonenkov, A.6
Gimeno, R.E.7
Adams, A.C.8
-
9
-
-
64349095231
-
Cold-activated brown adipose tissue in healthy men
-
van Marken Lichtenbelt W.D., Vanhommerig J.W., Smulders N.M., Drossaerts J.M., Kemerink G.J., Bouvy N.D., Schrauwen P., Teule G.J. Cold-activated brown adipose tissue in healthy men. N. Engl. J. Med. 2009, 360:1500-1508.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1500-1508
-
-
van Marken Lichtenbelt, W.D.1
Vanhommerig, J.W.2
Smulders, N.M.3
Drossaerts, J.M.4
Kemerink, G.J.5
Bouvy, N.D.6
Schrauwen, P.7
Teule, G.J.8
-
10
-
-
84930579383
-
Pharmacologic Effects of FGF21 Are Independent of the "Browning" of White Adipose Tissue
-
Véniant M.M., Sivits G., Helmering J., Komorowski R., Lee J., Fan W., Moyer C., Lloyd D.J. Pharmacologic Effects of FGF21 Are Independent of the "Browning" of White Adipose Tissue. Cell Metab. 2015, 21:731-738.
-
(2015)
Cell Metab.
, vol.21
, pp. 731-738
-
-
Véniant, M.M.1
Sivits, G.2
Helmering, J.3
Komorowski, R.4
Lee, J.5
Fan, W.6
Moyer, C.7
Lloyd, D.J.8
-
11
-
-
84863116228
-
Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ
-
Wei W., Dutchak P.A., Wang X., Ding X., Wang X., Bookout A.L., Goetz R., Mohammadi M., Gerard R.D., Dechow P.C., et al. Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ. Proc. Natl. Acad. Sci. USA 2012, 109:3143-3148.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 3143-3148
-
-
Wei, W.1
Dutchak, P.A.2
Wang, X.3
Ding, X.4
Wang, X.5
Bookout, A.L.6
Goetz, R.7
Mohammadi, M.8
Gerard, R.D.9
Dechow, P.C.10
-
12
-
-
61649127208
-
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
-
Xu J., Lloyd D.J., Hale C., Stanislaus S., Chen M., Sivits G., Vonderfecht S., Hecht R., Li Y.S., Lindberg R.A., et al. Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes 2009, 58:250-259.
-
(2009)
Diabetes
, vol.58
, pp. 250-259
-
-
Xu, J.1
Lloyd, D.J.2
Hale, C.3
Stanislaus, S.4
Chen, M.5
Sivits, G.6
Vonderfecht, S.7
Hecht, R.8
Li, Y.S.9
Lindberg, R.A.10
-
13
-
-
70350455732
-
Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects
-
Xu J., Stanislaus S., Chinookoswong N., Lau Y.Y., Hager T., Patel J., Ge H., Weiszmann J., Lu S.C., Graham M., et al. Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects. Am. J. Physiol. Endocrinol. Metab. 2009, 297:E1105-E1114.
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
, pp. E1105-E1114
-
-
Xu, J.1
Stanislaus, S.2
Chinookoswong, N.3
Lau, Y.Y.4
Hager, T.5
Patel, J.6
Ge, H.7
Weiszmann, J.8
Lu, S.C.9
Graham, M.10
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