Fibroblast growth factor 21 analogue LY2405319 lowers blood glucose in streptozotocin-induced insulin-deficient diabetic mice by restoring brown adipose tissue function

Diabetes, Obesity and Metabolism

Volumn 17, Issue 2, 2015, Pages 161-169

  Kim, J H ^a,b   Bae, K H ^b   Choi, Y K ^b   Go, Y ^b   Choe, M ^c   Jeon, Y H ^b,d   Lee, H W ^b,d   Koo, S H ^e   Perfield, J W ^f   Harris, R A ^g   Lee, I K ^a,b,d   Park, Keun Gyu ^b,d  

^a Kyungpook National University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c Keimyung University School of Medicine   (South Korea)

^d Kyungpook National University Hospital   (South Korea)

^e Korea University   (South Korea)

^f ELI LILLY AND COMPANY   (United States)

^g INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antidiabetic drug; Glucose uptake; Type 1 diabetes

Indexed keywords

ANTIDIABETIC AGENT; FIBROBLAST GROWTH FACTOR 21; FLUORODEOXYGLUCOSE F 18; GLUCOSE; LY 2405319; SODIUM CHLORIDE; UNCLASSIFIED DRUG; FIBROBLAST GROWTH FACTOR; GLUCOSE BLOOD LEVEL; INSULIN; LY2405319; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BROWN ADIPOSE TISSUE; CELL VACUOLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; ENERGY METABOLISM; GASTROCNEMIUS MUSCLE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN DEFICIENCY; LIPID METABOLISM; LUNG GAS EXCHANGE; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MORPHOLOGY; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PROTEIN BLOOD LEVEL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TREATMENT DURATION; WHITE ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; DEFICIENCY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DRUG EFFECTS; HOMEOSTASIS; INTRAPERITONEAL DRUG ADMINISTRATION; NONOBESE DIABETIC MOUSE; PATHOPHYSIOLOGY;

ADIPOSE TISSUE, BROWN; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; FIBROBLAST GROWTH FACTORS; HOMEOSTASIS; INJECTIONS, INTRAPERITONEAL; INSULIN; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; STREPTOZOCIN;

EID: 84921325509     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/dom.12408     Document Type: Article

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