MTOR inhibition of cardamonin on antiproliferation of A549 cells is involved in a FKBP12 independent fashion

Life Sciences

Volumn 99, Issue 1-2, 2014, Pages 44-51

  Tang, Ying ^a   Fang, Qi ^a   Shi, Daohua ^a   Niu, Peiguang ^a   Chen, Yaoyao ^a   Deng, Jie ^a  

^a Fujian Provincial Maternity and Child Health Hospital   (China)

Author keywords

Apoptosis; Cardamonin; FKBP12; mTOR; Proliferation; Rapamycin

Indexed keywords

2',4' DIHYDROXY 6' METHOXYCHALCONE; CARDAMONIN; DNA; FK 506 BINDING PROTEIN; FKBP12 BINDING PROTEIN; INTERLEUKIN 2; LIPOFECTAMINE; MAMMALIAN TARGET OF RAPAMYCIN; PLANT MEDICINAL PRODUCT; RAPAMYCIN; S6 KINASE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; METHYL THIAZOLYL TETRAZOLIUM ASSAY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

MAMMALIA;

APOPTOSIS; CARDAMONIN; CARDAMONIN (PUBCHEM CID: 641785); FKBP12; MTOR; PROLIFERATION; RAPAMYCIN;

ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONES; GENE EXPRESSION REGULATION; HUMANS; LUNG NEOPLASMS; TACROLIMUS BINDING PROTEIN 1A; TOR SERINE-THREONINE KINASES;

EID: 84896715514     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2014.01.066     Document Type: Article

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