MiR-125b regulates the proliferation of glioblastoma stem cells by targeting E2F2

FEBS Letters

Volumn 586, Issue 21, 2012, Pages 3831-3839

  Wu, Ning ^a   Xiao, Lin ^a   Zhao, Xiangzhong ^b   Zhao, Jin ^a   Wang, Jianpeng ^c   Wang, Fengxia ^a   Cao, Shousong ^d   Lin, Xiukun ^a,e  

^a INSTITUTE OF OCEANOLOGY   (China)

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^c Affiliated Hospital of Qingdao Medical University   (China)

^d ROSWELL PARK CANCER INSTITUTE   (United States)

^e CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Brain tumor; E2F2; Glioblastoma stem cell; microRNA; microRNA 125b

Indexed keywords

CD133 ANTIGEN; MICRORNA 125B; TRANSCRIPTION FACTOR E2F2;

3' UNTRANSLATED REGION; ARTICLE; BINDING SITE; CANCER STEM CELL; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GLIOBLASTOMA; GLIOBLASTOMA STEM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

3' UNTRANSLATED REGIONS; ANTIGENS, CD; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; E2F2 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; GLYCOPROTEINS; HUMANS; MICRORNAS; NEOPLASTIC STEM CELLS; PEPTIDES; PROTEIN BINDING; TUMOR MARKERS, BIOLOGICAL;

EID: 84868159450     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.08.023     Document Type: Article

References (35)

1. J. Clarke, N. Butowski, and S. Chang Recent advances in therapy for glioblastoma Arch. Neurol. 67 2010 279 283
2. J.E. Dick Breast cancer stem cells revealed Proc. Natl. Acad. Sci. USA 100 2003 3547 3549
3. S.K. Singh, I.D. Clarke, M. Terasaki, V.E. Bonn, C. Hawkins, J. Squire, and P.B. Dirks Identification of a cancer stem cell in human brain tumors Cancer Res. 63 2003 5821 5828
4. R. Galli, E. Binda, U. Orfanelli, B. Cipelletti, A. Gritti, S. De Vitis, R. Fiocco, C. Foroni, F. Dimeco, and A. Vescovi Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma Cancer Res. 64 2004 7011 7021
5. T. Reya, S.J. Morrison, M.F. Clarke, and I.L. Weissman Stem cells, cancer, and cancer stem cells Nature 414 2001 105 111
6. S.K. Singh, C. Hawkins, I.D. Clarke, J.A. Squire, J. Bayani, T. Hide, R.M. Henkelman, M.D. Cusimano, and P.B. Dirks Identification of human brain tumour initiating cells Nature 432 2004 396 401
7. S.C. Yu, Y.F. Ping, L. Yi, Z.H. Zhou, J.H. Chen, X.H. Yao, L. Gao, J.M. Wang, and X.W. Bian Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87 Cancer Lett. 265 2008 124 134
8. S.G. Piccirillo, and A.L. Vescovi Brain tumour stem cells: possibilities of new therapeutic strategies Expert Opin. Biol. Ther. 7 2007 1129 1135
9. M. Inui, G. Martello, and S. Piccolo microRNA control of signal transduction Nat. Rev. Mol. Cell Biol. 11 2010 252 263
10. A.L. Zimmerman, and S. Wu microRNAs, cancer and cancer stem cells Cancer Lett. 300 2011 10 19
11. F. Yu, H. Yao, P. Zhu, X. Zhang, Q. Pan, C. Gong, Y. Huang, X. Hu, F. Su, J. Lieberman, and E. Song Let-7 regulates self renewal and tumorigenicity of breast cancer cells Cell 131 2007 1109 1123
12. F. Guessous, Y. Zhang, A. Kofman, A. Catania, Y. Li, D. Schiff, B. Purow, and R. Abounader MicroRNA-34a is tumor suppressive in brain tumors and glioma stem cells Cell Cycle 9 2010
13. Y.S. Lee, H.K. Kim, S. Chung, K.S. Kim, and A. Dutta Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation J. Biol. Chem. 280 2005 16635 16641
14. L. Wu, and J.G. Belasco micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells Mol. Cell. Biol. 25 2005 9198 9208
15. M.T. Le, H. Xie, B. Zhou, P.H. Chia, P. Rizk, M. Um, G. Udolph, H. Yang, B. Lim, and H.F. Lodish microRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets Mol. Cell. Biol. 29 2009 5290 5305
16. J.H. Klusmann, Z. Li, K. Böhmer, A. Maroz, M.L. Koch, S. Emmrich, F.J. Godinho, S.H. Orkin, and D. Reinhardt miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia Genes Dev. 24 2009 478 490
17. M.T. Le, C. Teh, N. Shyh-Chang, H. Xie, B. Zhou, V. Korzh, H.F. Lodish, and B. Lim microRNA-125b is a novel negative regulator of p53 Genes Dev. 23 2009 862 876
18. H.F. Xia, T.Z. He, C.M. Liu, Y. Cui, P.P. Song, X.H. Jin, and X. Ma miR-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf Cell. Physiol. Biochem. 23 2009 347 358
19. L. Shi, J. Zhang, T. Pan, J. Zhou, W. Gong, N. Liu, Z. Fu, and Y. You miR-125b is critical for the suppression of human U251 glioma stem cell proliferation Brain Res. 1312 2010 120 126
20. M. Zhou microRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression J. Biol. Chem. 285 2010 21496 21507
21. N. Wu, X. Zhao, M. Liu, H. Liu, W. Yao, Y. Zhang, S. Cao, and X. Lin Role of microRNA-26b in glioma development and its mediated regulation on EphA2 PLoS ONE 6 2011 e16264
22. L.A. Genovesi, K.W. Carter, N.G. Gottardo, K.M. Giles, and P.B. Dallas Integrated analysis of miRNA and mRNA expression in childhood medulloblastoma compared with neural stem cells PLoS ONE 6 2011 e23935
23. Y. Chen, and R.L. Stallings Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis Cancer Res. 67 2007 976 983
24. A.A. Chaudhuri, A.Y. So, A. Mehta, A. Minisandram, N. Sinha, V.D. Jonsson, D.S. Rao, R.M. O'Connell, and D. Baltimore Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A Proc. Natl. Acad. Sci. USA 109 2012 4233 4238
25. M. Zhou, Z. Liu, Y. Zhao, Y. Ding, H. Liu, Y. Xi, W. Xiong, G. Li, J. Lu, O. Fodstad, A.I. Riker, and M. Tan microRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression J. Biol. Chem. 285 2009 21496 21507
26. N. Gefen, V. Binder, M. Zaliova, Y. Linka, M. Morrow, A. Novosel, L. Edry, L. Hertzberg, N. Shomron, O. Williams, J. Trka, A. Borkhardt, and S. Izraeli Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53 Leukemia 24 2009 89 96
27. M.T. Le, N. Shyh-Chang, S.L. Khaw, L. Chin, C. Teh, J. Tay, E. O'Day, V. Korzh, H. Yang, A. Lal, J. Lieberman, H.F. Lodish, and B. Lim Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs PLoS Genet. 7 2011 e1002242
28. G.K. Scott, A. Goga, D. Bhaumik, C.E. Berger, C.S. Sullivan, and C.C. Benz Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b J. Biol. Chem. 282 2007 1479 1486
29. Y. Mizuno, K. Yagi, Y. Tokuzawa, Y. Kanesaki-Yatsuka, T. Suda, T. Katagiri, T. Fukuda, M. Maruyama, A. Okuda, T. Amemiya, Y. Kondoh, H. Tashiro, and Y. Okazaki miR-125b inhibits osteoblastic differentiation by down-regulation of cell proliferation Biochem. Biophys. Res. Commun. 368 2008 267 272
30. M.H. Hofmann, J. Heinrich, G. Radziwil, and K. Moelling A short hairpin DNA analogous to miR-125b inhibits C-Raf expression, proliferation, and survival of breast cancer cells Mol. Cancer Res. 7 2009 1635 1644
31. L. Huang, J. Luo, Q. Cai, Q. Pan, H. Zeng, Z. Guo, W. Dong, J. Huang, and T. Lin microRNA-125b suppresses the development of bladder cancer by targeting E2F3 Int. J. Cancer 128 2011 1758 1769
32. S.D. Hatfield, H.R. Shcherbata, K.A. Fischer, K. Nakahara, R.W. Carthew, and H. Ruohola-Baker Stem cell division is regulated by the microRNA pathway Nature 435 2005 974 978
33. K. Helin Regulation of cell proliferation by the E2F transcription factors Curr. Opin. Genet. Dev. 8 1998 28 35
34. B.D. Aguda, Y. Kim, M.G. Piper-Hunter, A. Friedman, and C.B. Marsh microRNA regulation of a cancer network: consequences of the feedback loops involving miR-17-92, E2F, and Myc Proc. Natl. Acad. Sci. USA 105 2008 19678 19683
35. A. Lal, F. Navarro, C.A. Maher, L.E. Maliszewski, N. Yan, E. O'Day, D. Chowdhury, D.M. Dykxhoorn, P. Tsai, O. Hofmann, K.G. Becker, M. Gorospe, W. Hide, and J. Lieberman miR-24 inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3′UTR microRNA recognition elements Mol. Cell 35 2009 610 625