메뉴 건너뛰기




Volumn 33, Issue 1, 2016, Pages 217-236

A Promising Emodin-Loaded Poly (Lactic-Co-Glycolic Acid)-d-α-Tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles for Liver Cancer Therapy

Author keywords

Emodin; liver cancer; liver targeting property; nanoparticles; PLGA TPGS

Indexed keywords

COUMARIN DERIVATIVE; CURCUMIN 6; EMODIN; FLUOROURACIL; NANOPARTICLE; PHENYLPHOSPHONOTHIOIC ACID O ETHYL O (4 NITROPHENYL) ESTER; POLYGLACTIN; TOCOFERSOLAN; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; DELAYED RELEASE FORMULATION; LACTIC ACID; MACROGOL DERIVATIVE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

EID: 84952872439     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-015-1781-4     Document Type: Article
Times cited : (35)

References (40)
  • 1
    • 63049133092 scopus 로고    scopus 로고
    • Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005
    • 19224838 2668555
    • Altekruse SF, McGlynn KA, Reichman ME. Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005. J Clin Oncol. 2009;27(9):1485-91.
    • (2009) J Clin Oncol , vol.27 , Issue.9 , pp. 1485-1491
    • Altekruse, S.F.1    McGlynn, K.A.2    Reichman, M.E.3
  • 3
    • 84935036863 scopus 로고    scopus 로고
    • The possibility of traditional Chinese medicine as maintenance therapy for advanced nonsmall cell lung cancer
    • 25165478 4137694
    • Xu W, Yang G, Xu Y, Zhang Q, Fu Q, Yu J, et al. The possibility of traditional Chinese medicine as maintenance therapy for advanced nonsmall cell lung cancer. Evid Based Complement Alternat Med. 2014;2014:278917.
    • (2014) Evid Based Complement Alternat Med , vol.2014 , pp. 278917
    • Xu, W.1    Yang, G.2    Xu, Y.3    Zhang, Q.4    Fu, Q.5    Yu, J.6
  • 4
    • 79851510937 scopus 로고    scopus 로고
    • Herbal therapy use by cancer patients: A literature review on case reports
    • 21185719 3057114
    • Olaku O, White JD. Herbal therapy use by cancer patients: a literature review on case reports. Eur J Cancer. 2011;47(4):508-14.
    • (2011) Eur J Cancer , vol.47 , Issue.4 , pp. 508-514
    • Olaku, O.1    White, J.D.2
  • 5
    • 77249157217 scopus 로고    scopus 로고
    • Emodin enhances sensitivity of gallbladder cancer cells to platinum drugs via glutathion depletion and MRP1 downregulation
    • 20005210
    • Wang W, Sun YP, Huang XZ, He M, Chen YY, Shi GY, et al. Emodin enhances sensitivity of gallbladder cancer cells to platinum drugs via glutathion depletion and MRP1 downregulation. Biochem Pharmacol. 2010;79(8):1134-40.
    • (2010) Biochem Pharmacol , vol.79 , Issue.8 , pp. 1134-1140
    • Wang, W.1    Sun, Y.P.2    Huang, X.Z.3    He, M.4    Chen, Y.Y.5    Shi, G.Y.6
  • 6
    • 73449090077 scopus 로고    scopus 로고
    • Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo
    • Chun GW, Jun QY, Bei ZL, Dan TJ, Chong W, Liang Z, et al. Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo. Eur J Pharmacol. 2010;627(1-3):33-41.
    • (2010) Eur J Pharmacol , vol.627 , Issue.1-3 , pp. 33-41
    • Chun, G.W.1    Jun, Q.Y.2    Bei, Z.L.3    Dan, T.J.4    Chong, W.5    Liang, Z.6
  • 7
    • 2942644401 scopus 로고    scopus 로고
    • Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells
    • 15207375
    • Chen HC, Hsieh WT, Chang WC, Chung JG. Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells. Food Chem Toxicol. 2004;42(8):1251-7.
    • (2004) Food Chem Toxicol , vol.42 , Issue.8 , pp. 1251-1257
    • Chen, H.C.1    Hsieh, W.T.2    Chang, W.C.3    Chung, J.G.4
  • 8
    • 0037031787 scopus 로고    scopus 로고
    • The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines
    • 12175703
    • Kuo PL, Lin TC, Lin CC. The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines. Life Sci. 2002;71(16):1879-92.
    • (2002) Life Sci , vol.71 , Issue.16 , pp. 1879-1892
    • Kuo, P.L.1    Lin, T.C.2    Lin, C.C.3
  • 9
    • 0042206721 scopus 로고    scopus 로고
    • Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9
    • Srinivas G, Anto RJ, Srinivas P, Vidhyalakshmi S, Senan VP, Karunagaran D. Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9. Eur J Phacmacol. 2003;473(2-3):117-25.
    • (2003) Eur J Phacmacol , vol.473 , Issue.2-3 , pp. 117-125
    • Srinivas, G.1    Anto, R.J.2    Srinivas, P.3    Vidhyalakshmi, S.4    Senan, V.P.5    Karunagaran, D.6
  • 10
    • 0037190123 scopus 로고    scopus 로고
    • Chemopreventive effects of emodin and cassiamin B in mouse skin carcinogenesis
    • 12048158
    • Koyama J, Morita I, Tagahara K, Nobukuni Y, Mukainaka T, Kuchide M, et al. Chemopreventive effects of emodin and cassiamin B in mouse skin carcinogenesis. Cancer Lett. 2002;182(2):135-9.
    • (2002) Cancer Lett , vol.182 , Issue.2 , pp. 135-139
    • Koyama, J.1    Morita, I.2    Tagahara, K.3    Nobukuni, Y.4    Mukainaka, T.5    Kuchide, M.6
  • 11
    • 27244437283 scopus 로고    scopus 로고
    • Gene expression alteration during redox-dependent enhancement of arsenic cytotoxicity by emodin in HeLa cells
    • 16045814
    • Wang XJ, Yang J, Cang H, Zou YQ, Yi J. Gene expression alteration during redox-dependent enhancement of arsenic cytotoxicity by emodin in HeLa cells. Cell Res. 2005;15(7):511-22.
    • (2005) Cell Res , vol.15 , Issue.7 , pp. 511-522
    • Wang, X.J.1    Yang, J.2    Cang, H.3    Zou, Y.Q.4    Yi, J.5
  • 12
    • 79955784689 scopus 로고    scopus 로고
    • Targeting the brain with PEG-PLGA nanoparticles modified with phage-displayed peptides
    • 21470674 3727047
    • Li J, Feng L, Fan L, Zha Y, Guo L, Zhang Q, et al. Targeting the brain with PEG-PLGA nanoparticles modified with phage-displayed peptides. Biomaterials. 2011;32(21):4943-50.
    • (2011) Biomaterials , vol.32 , Issue.21 , pp. 4943-4950
    • Li, J.1    Feng, L.2    Fan, L.3    Zha, Y.4    Guo, L.5    Zhang, Q.6
  • 13
    • 84892624324 scopus 로고    scopus 로고
    • Chitosan nanoparticles for siRNA delivery: Optimizing formulation to increase stability and efficiency
    • 24389132
    • Ragelle H, Riva R, Vandermeulen G, Naeye B, Pourcelle V, Le Duff CS, et al. Chitosan nanoparticles for siRNA delivery: optimizing formulation to increase stability and efficiency. J Control Release. 2014;176:54-63.
    • (2014) J Control Release , vol.176 , pp. 54-63
    • Ragelle, H.1    Riva, R.2    Vandermeulen, G.3    Naeye, B.4    Pourcelle, V.5    Le Duff, C.S.6
  • 14
    • 38349154138 scopus 로고    scopus 로고
    • Nano/micro technologies for delivering macromolecular therapeutics using poly (D, L-lactide-co-glycolide) and its derivatives
    • 18083265
    • Mundargi RC, Babu VR, Rangaswamy V, Patel P, Aminabhavi TM. Nano/micro technologies for delivering macromolecular therapeutics using poly (D, L-lactide-co-glycolide) and its derivatives. J Control Release. 2008;125(3):193-209.
    • (2008) J Control Release , vol.125 , Issue.3 , pp. 193-209
    • Mundargi, R.C.1    Babu, V.R.2    Rangaswamy, V.3    Patel, P.4    Aminabhavi, T.M.5
  • 15
    • 33646559887 scopus 로고    scopus 로고
    • Preparation of DHAQ-loaded mPEG-PLGA-mPEG nanoparticles and evaluation of drug release behaviors in vitro/in vivo
    • 16691348
    • Duan Y, Sun X, Gong T, Wang Q, Zhang Z. Preparation of DHAQ-loaded mPEG-PLGA-mPEG nanoparticles and evaluation of drug release behaviors in vitro/in vivo. J Mater Sci Mater Med. 2006;17(6):509-16.
    • (2006) J Mater Sci Mater Med , vol.17 , Issue.6 , pp. 509-516
    • Duan, Y.1    Sun, X.2    Gong, T.3    Wang, Q.4    Zhang, Z.5
  • 16
    • 24644459310 scopus 로고    scopus 로고
    • Nanoparticles of poly (lactide)/Vitamin E TPGS copolymer for cancer chemotherapy: Synthesis, formulation, characterization and in vitro drug release
    • 16024075
    • Zhang Z, Feng SS. Nanoparticles of poly (lactide)/vitamin E TPGS copolymer for cancer chemotherapy: synthesis, formulation, characterization and in vitro drug release. Biomaterials. 2006;27(2):262-70.
    • (2006) Biomaterials , vol.27 , Issue.2 , pp. 262-270
    • Zhang, Z.1    Feng, S.S.2
  • 17
    • 0037426719 scopus 로고    scopus 로고
    • A novel controlled release formulation for the anticancer drug paclitaxel (Taxol®): PLGA nanoparticles containing Vitamin E TPGS
    • 12490371
    • Mu L, Feng SS. A novel controlled release formulation for the anticancer drug paclitaxel (Taxol®): PLGA nanoparticles containing vitamin E TPGS. J Control Release. 2003;86(1):33-48.
    • (2003) J Control Release , vol.86 , Issue.1 , pp. 33-48
    • Mu, L.1    Feng, S.S.2
  • 18
    • 34247639105 scopus 로고    scopus 로고
    • Modified paclitaxel-loaded nanoparticles for inhibition of hyperplasia in a rabbit arterial balloon injury model
    • 17372684
    • Mei L, Sun H, Jin X, Zhu D, Sun R, Zhang M, et al. Modified paclitaxel-loaded nanoparticles for inhibition of hyperplasia in a rabbit arterial balloon injury model. Pharm Res. 2007;24(5):955-62.
    • (2007) Pharm Res , vol.24 , Issue.5 , pp. 955-962
    • Mei, L.1    Sun, H.2    Jin, X.3    Zhu, D.4    Sun, R.5    Zhang, M.6
  • 19
    • 78649331839 scopus 로고    scopus 로고
    • Nanoparticles of poly(lactide-co-glycolide)-d-a-tocopheryl polyethylene glycol 1000 succinate random copolymer for cancer treatment
    • 20596457 2893931
    • Ma Y, Zheng Y, Liu K, Tian G, Tian Y, Xu L, et al. Nanoparticles of poly(lactide-co-glycolide)-d-a-tocopheryl polyethylene glycol 1000 succinate random copolymer for cancer treatment. Nanoscale Res Lett. 2010;5:1161-9.
    • (2010) Nanoscale Res Lett , vol.5 , pp. 1161-1169
    • Ma, Y.1    Zheng, Y.2    Liu, K.3    Tian, G.4    Tian, Y.5    Xu, L.6
  • 20
    • 79952696986 scopus 로고    scopus 로고
    • Oral delivery of DMAB-modified docetaxel-loaded PLGA-TPGS nanoparticles for cancer chemotherapy
    • Chen HB, Zheng Y, Tian G, Tian Y, Zeng XW, Liu G, et al. Oral delivery of DMAB-modified docetaxel-loaded PLGA-TPGS nanoparticles for cancer chemotherapy. Nanoscale Res Lett. 2011;6(1):33-48.
    • (2011) Nanoscale Res Lett , vol.6 , Issue.1 , pp. 33-48
    • Chen, H.B.1    Zheng, Y.2    Tian, G.3    Tian, Y.4    Zeng, X.W.5    Liu, G.6
  • 21
    • 84875391774 scopus 로고    scopus 로고
    • The applications of Vitamin E TPGS in drug delivery
    • 23485439
    • Guo Y, Luo J, Tan S, Otieno BO, Zhang Z. The applications of vitamin E TPGS in drug delivery. Eur J Pharm Sci. 2013;49(2):175-86.
    • (2013) Eur J Pharm Sci , vol.49 , Issue.2 , pp. 175-186
    • Guo, Y.1    Luo, J.2    Tan, S.3    Otieno, B.O.4    Zhang, Z.5
  • 22
    • 84891373113 scopus 로고    scopus 로고
    • Co-delivery of chemotherapeutic drugs with Vitamin E TPGS by porous PLGA nanoparticles for enhanced chemotherapy against multi-drug resistance
    • 24360574
    • Zhu H, Chen H, Zeng X, Wang Z, Zhang X, Wu Y, et al. Co-delivery of chemotherapeutic drugs with vitamin E TPGS by porous PLGA nanoparticles for enhanced chemotherapy against multi-drug resistance. Biomaterials. 2014;35(7):2391-400.
    • (2014) Biomaterials , vol.35 , Issue.7 , pp. 2391-2400
    • Zhu, H.1    Chen, H.2    Zeng, X.3    Wang, Z.4    Zhang, X.5    Wu, Y.6
  • 23
    • 84907329099 scopus 로고    scopus 로고
    • Dorzolamide-loaded PLGA/Vitamin E TPGS nanoparticles for glaucoma therapy: Pharmacoscintigraphy study and evaluation of extended ocular hypotensive effect in rabbits
    • 25159319
    • Warsi MH, Anwar M, Garg V, Jain GK, Talegaonkar S, Ahmad FJ, et al. Dorzolamide-loaded PLGA/vitamin E TPGS nanoparticles for glaucoma therapy: Pharmacoscintigraphy study and evaluation of extended ocular hypotensive effect in rabbits. Colloids Surf B: Biointerfaces. 2014;122:423-31.
    • (2014) Colloids Surf B: Biointerfaces , vol.122 , pp. 423-431
    • Warsi, M.H.1    Anwar, M.2    Garg, V.3    Jain, G.K.4    Talegaonkar, S.5    Ahmad, F.J.6
  • 24
    • 0042634190 scopus 로고    scopus 로고
    • Fluorescence and electron microscopy probes for cellular and tissue uptake of poly (d, l-lactide-co-glycolide) nanoparticles
    • 12927382
    • Panyam J, Sahoo SK, Prabha S, Bargar T, Labhasetwar V. Fluorescence and electron microscopy probes for cellular and tissue uptake of poly (d, l-lactide-co-glycolide) nanoparticles. Int J Pharm. 2003;262(1/2):1-11.
    • (2003) Int J Pharm , vol.262 , Issue.1-2 , pp. 1-11
    • Panyam, J.1    Sahoo, S.K.2    Prabha, S.3    Bargar, T.4    Labhasetwar, V.5
  • 25
    • 24144499309 scopus 로고    scopus 로고
    • Paired helical filaments (PHFs) are a family of single filament structures with a common helical turn period: Negatively stained PHF imaged by TEM and measured before and after sonication, deglycosylation, and dephosphorylation
    • 16104003
    • Ruben GC, Wang JZ, Iqbal K, Grundke-Iqbal I. Paired helical filaments (PHFs) are a family of single filament structures with a common helical turn period: negatively stained PHF imaged by TEM and measured before and after sonication, deglycosylation, and dephosphorylation. Microsc Res Tech. 2005;67(3-4):175-95.
    • (2005) Microsc Res Tech , vol.67 , Issue.3-4 , pp. 175-195
    • Ruben, G.C.1    Wang, J.Z.2    Iqbal, K.3    Grundke-Iqbal, I.4
  • 26
    • 77951800175 scopus 로고    scopus 로고
    • Comparison of three different extraction methods and HPLC determination of the anthraquinones aloe-emodine, emodine, rheine, chrysophanol and physcione in the bark of Rhamnus alpinus L. (Rhamnaceae)
    • 20024894
    • Genovese S, Tammaro F, Menghini L, Carlucci G, Epifano F, Locatelli M. Comparison of three different extraction methods and HPLC determination of the anthraquinones aloe-emodine, emodine, rheine, chrysophanol and physcione in the bark of Rhamnus alpinus L. (Rhamnaceae). Phytochem Anal. 2010;21(3):261-7.
    • (2010) Phytochem Anal , vol.21 , Issue.3 , pp. 261-267
    • Genovese, S.1    Tammaro, F.2    Menghini, L.3    Carlucci, G.4    Epifano, F.5    Locatelli, M.6
  • 27
    • 65449147439 scopus 로고    scopus 로고
    • Quantitative HPLC determination and extraction of anthraquinones in Senna alata leaves
    • 19298705
    • Panichayupakaranant P, Sakunpak A, Sakunphueak A. Quantitative HPLC determination and extraction of anthraquinones in Senna alata leaves. J Chromatogr Sci. 2009;47(3):197-200.
    • (2009) J Chromatogr Sci , vol.47 , Issue.3 , pp. 197-200
    • Panichayupakaranant, P.1    Sakunpak, A.2    Sakunphueak, A.3
  • 28
    • 84932603380 scopus 로고    scopus 로고
    • A novel oleanolic acid-loaded PLGA-TPGS nanoparticle for liver cancer treatment.
    • Bao X, Gao M, Xu H, Liu KX, Zhang CH, Jiang N, et al. A novel oleanolic acid-loaded PLGA-TPGS nanoparticle for liver cancer treatment. Drug Dev Ind Pharm. 2015;41(7):1193-203.
    • (2015) Drug Dev Ind Pharm. , vol.41 , Issue.7 , pp. 1193-1203
    • Bao, X.1    Gao, M.2    Xu, H.3    Liu, K.X.4    Zhang, C.H.5    Jiang, N.6
  • 29
    • 77952828382 scopus 로고    scopus 로고
    • Preparation and in-vitro/in-vivo evaluation of surface-modified poly (lactide-co-glycolide) fluorescent nanoparticles
    • 20604830
    • Pamujula S, Hazari S, Bolden G, Graves RA, Chinta DM, Dash S, et al. Preparation and in-vitro/in-vivo evaluation of surface-modified poly (lactide-co-glycolide) fluorescent nanoparticles. J Pharm Pharmacol. 2010;62(4):422-9.
    • (2010) J Pharm Pharmacol , vol.62 , Issue.4 , pp. 422-429
    • Pamujula, S.1    Hazari, S.2    Bolden, G.3    Graves, R.A.4    Chinta, D.M.5    Dash, S.6
  • 30
    • 84911493623 scopus 로고    scopus 로고
    • Preparation and characterization of curcumin thermosensitive hydrogels for intratumoral injection treatment
    • 24059282
    • Gao M, Xu H, Zhang CH, Liu KX, Bao X, Chu QC, et al. Preparation and characterization of curcumin thermosensitive hydrogels for intratumoral injection treatment. Drug Dev Ind Pharm. 2014;40(11):1557-64.
    • (2014) Drug Dev Ind Pharm , vol.40 , Issue.11 , pp. 1557-1564
    • Gao, M.1    Xu, H.2    Zhang, C.H.3    Liu, K.X.4    Bao, X.5    Chu, Q.C.6
  • 31
    • 84868089439 scopus 로고    scopus 로고
    • Emodin induces Panc-1 cell apoptosis via declining the mitochondrial membrane potential
    • 22992976
    • Liu JX, Zhang JH, Li HH, Lai FJ, Chen KJ, Chen H, et al. Emodin induces Panc-1 cell apoptosis via declining the mitochondrial membrane potential. Oncol Rep. 2012;28(6):1991-6.
    • (2012) Oncol Rep , vol.28 , Issue.6 , pp. 1991-1996
    • Liu, J.X.1    Zhang, J.H.2    Li, H.H.3    Lai, F.J.4    Chen, K.J.5    Chen, H.6
  • 32
    • 80051747340 scopus 로고    scopus 로고
    • Gadolinium-conjugated PLA-PEG nanoparticles as liver targeted molecular MRI contrast agent
    • 21091273
    • Chen Z, Yu D, Liu C, Yang X, Zhang N, Ma C, et al. Gadolinium-conjugated PLA-PEG nanoparticles as liver targeted molecular MRI contrast agent. J Drug Target. 2011;19(8):657-65.
    • (2011) J Drug Target , vol.19 , Issue.8 , pp. 657-665
    • Chen, Z.1    Yu, D.2    Liu, C.3    Yang, X.4    Zhang, N.5    Ma, C.6
  • 33
    • 84893369546 scopus 로고    scopus 로고
    • Pharmacokinetics difference of multiple active constituents from decoction and maceration of Fuzi Xiexin Tang after oral administration in rat by UPLC-MS/MS
    • 24469098
    • Zhang Q, Ma YM, Wang ZT, Wang CH. Pharmacokinetics difference of multiple active constituents from decoction and maceration of Fuzi Xiexin Tang after oral administration in rat by UPLC-MS/MS. J Pharm Biomed Anal. 2014;92:35-46.
    • (2014) J Pharm Biomed Anal , vol.92 , pp. 35-46
    • Zhang, Q.1    Ma, Y.M.2    Wang, Z.T.3    Wang, C.H.4
  • 34
    • 84866563535 scopus 로고    scopus 로고
    • Emodin studies on pharmacokinetics and distribution in Rat liver after polygonum cuspidatum Sieb. et Zucc. Extract administration
    • Peng J, Song ZF, Ma C. Emodin studies on pharmacokinetics and distribution in Rat liver after polygonum cuspidatum Sieb. et Zucc. Extract administration. World Sci Technol. 2008;10(1):64-7.
    • (2008) World Sci Technol , vol.10 , Issue.1 , pp. 64-67
    • Peng, J.1    Song, Z.F.2    Ma, C.3
  • 35
    • 84896735135 scopus 로고    scopus 로고
    • Marked effects of combined TPGS and PVA emulsifiers in the fabrication of etoposide-loaded PLGA-PEG nanoparticles: in vitro and in vivo evaluation
    • 24451238
    • Saadati R, Dadashzadeh S. Marked effects of combined TPGS and PVA emulsifiers in the fabrication of etoposide-loaded PLGA-PEG nanoparticles: in vitro and in vivo evaluation. Int J Pharm. 2014;464(1-2):135-44.
    • (2014) Int J Pharm , vol.464 , Issue.1-2 , pp. 135-144
    • Saadati, R.1    Dadashzadeh, S.2
  • 36
    • 78650678085 scopus 로고    scopus 로고
    • Unintended potential impact of perfect sink conditions on PLGA degradation in microparticles
    • 21056644
    • Klose D, Delplace C, Siepmann J. Unintended potential impact of perfect sink conditions on PLGA degradation in microparticles. Int J Pharm. 2011;404(1-2):75-82.
    • (2011) Int J Pharm , vol.404 , Issue.1-2 , pp. 75-82
    • Klose, D.1    Delplace, C.2    Siepmann, J.3
  • 37
    • 84883359516 scopus 로고    scopus 로고
    • Intravitreal administration of dexamethasone-loaded PLGA-TPGS nanoparticles for the treatment of posterior segment diseases
    • 23980509
    • Yang C, Jiang L, Bu S, Zhang L, Xie X, Zeng Q, et al. Intravitreal administration of dexamethasone-loaded PLGA-TPGS nanoparticles for the treatment of posterior segment diseases. J Biomed Nanotechnol. 2013;9(9):1617-23.
    • (2013) J Biomed Nanotechnol , vol.9 , Issue.9 , pp. 1617-1623
    • Yang, C.1    Jiang, L.2    Bu, S.3    Zhang, L.4    Xie, X.5    Zeng, Q.6
  • 38
    • 57649242732 scopus 로고    scopus 로고
    • Effect of a vascular access nurse coordinator to reduce central venous catheter use in incident hemodialysis patients: A quality improvement report
    • 18805614
    • Polkinghorne KR, Seneviratne M, Kerr PG. Effect of a vascular access nurse coordinator to reduce central venous catheter use in incident hemodialysis patients: a quality improvement report. Am J Kidney Dis. 2009;53(1):99-106.
    • (2009) Am J Kidney Dis , vol.53 , Issue.1 , pp. 99-106
    • Polkinghorne, K.R.1    Seneviratne, M.2    Kerr, P.G.3
  • 39
    • 60749108001 scopus 로고    scopus 로고
    • Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
    • 19070661
    • Maeda H, Bharate GY, Daruwalla J. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect. Eur J Pharm Biopharm. 2009;71(3):409-19.
    • (2009) Eur J Pharm Biopharm , vol.71 , Issue.3 , pp. 409-419
    • Maeda, H.1    Bharate, G.Y.2    Daruwalla, J.3
  • 40
    • 84875996201 scopus 로고    scopus 로고
    • Decreased reticuloendothelial system clearance and increased blood half-life and immune cell labeling for nano-and micron-sized superparamagnetic iron-oxide particles upon pre-treatment with Intralipid
    • 23396002 3640706
    • Liu L, Hitchens TK, Ye Q, Wu Y, Barbe B, Prior DE, et al. Decreased reticuloendothelial system clearance and increased blood half-life and immune cell labeling for nano-and micron-sized superparamagnetic iron-oxide particles upon pre-treatment with Intralipid. Biochim Biophys Acta. 2013;1830(6):3447-53.
    • (2013) Biochim Biophys Acta , vol.1830 , Issue.6 , pp. 3447-3453
    • Liu, L.1    Hitchens, T.K.2    Ye, Q.3    Wu, Y.4    Barbe, B.5    Prior, D.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.