메뉴 건너뛰기




Volumn 27, Issue , 2016, Pages 181-192

A combined omics approach to evaluate the effects of dietary curcumin on colon inflammation in the Mdr1a-/- mouse model of inflammatory bowel disease

Author keywords

Alpha catenin; Curcuma longa; Extracellular matrix; Oligonucleotide array sequence analysis; Two dimensional difference gel electrophoresis

Indexed keywords

ALPHA CATENIN; CURCUMIN; FN1 PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEOME; TNFSF12 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTOME; UNCLASSIFIED DRUG; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 3;

EID: 84952862240     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2015.08.030     Document Type: Article
Times cited : (37)

References (60)
  • 1
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • Xavier R.J., Podolsky D.K. Unravelling the pathogenesis of inflammatory bowel disease. Nature 2007, 448:427-434.
    • (2007) Nature , vol.448 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 2
    • 80655149205 scopus 로고    scopus 로고
    • New IBD genetics: common pathways with other diseases
    • Lees C.W., Barrett J.C., Parkes M., Satsangi J. New IBD genetics: common pathways with other diseases. Gut 2011, 60:1739-1753.
    • (2011) Gut , vol.60 , pp. 1739-1753
    • Lees, C.W.1    Barrett, J.C.2    Parkes, M.3    Satsangi, J.4
  • 3
    • 0032534043 scopus 로고    scopus 로고
    • A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis
    • Panwala C.M., Jones J.C., Viney J.L. A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. J Immunol 1998, 161:5733-5744.
    • (1998) J Immunol , vol.161 , pp. 5733-5744
    • Panwala, C.M.1    Jones, J.C.2    Viney, J.L.3
  • 4
    • 18244395058 scopus 로고    scopus 로고
    • The mdr1a-/- mouse model of spontaneous colitis: a relevant and appropriate animal model to study inflammatory bowel disease
    • Wilk J.N., Bilsborough J., Viney J.L. The mdr1a-/- mouse model of spontaneous colitis: a relevant and appropriate animal model to study inflammatory bowel disease. Immunol Res 2005, 31:151-159.
    • (2005) Immunol Res , vol.31 , pp. 151-159
    • Wilk, J.N.1    Bilsborough, J.2    Viney, J.L.3
  • 5
    • 38149071725 scopus 로고    scopus 로고
    • Characterization of inflammation in mdr1a-/- mice and identification of related gene expression changes in colonic epithelial cells
    • Dommels Y.E.M., Butts C., Zhu S.T., Davy M., Martell S., Hedderly D., et al. Characterization of inflammation in mdr1a-/- mice and identification of related gene expression changes in colonic epithelial cells. Genes Nutr 2007, 2:209-223.
    • (2007) Genes Nutr , vol.2 , pp. 209-223
    • Dommels, Y.E.M.1    Butts, C.2    Zhu, S.T.3    Davy, M.4    Martell, S.5    Hedderly, D.6
  • 6
    • 33947492645 scopus 로고    scopus 로고
    • Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel disease
    • Te Velde A.A., De Kort F., Sterrenburg E., Pronk I., Ten Kate F.J.W., Hommes D.W., et al. Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel disease. Inflamm Bowel Dis 2007, 13:325-330.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 325-330
    • Te Velde, A.A.1    De Kort, F.2    Sterrenburg, E.3    Pronk, I.4    Ten Kate, F.J.W.5    Hommes, D.W.6
  • 7
    • 33846889718 scopus 로고    scopus 로고
    • "Spicing up" of the immune system by curcumin
    • Jagetia G.C., Aggarwal B.B. "Spicing up" of the immune system by curcumin. J Clin Immunol 2007, 27:19-35.
    • (2007) J Clin Immunol , vol.27 , pp. 19-35
    • Jagetia, G.C.1    Aggarwal, B.B.2
  • 8
    • 80052168264 scopus 로고    scopus 로고
    • Curcumin for inflammatory bowel disease: a review of human studies
    • Taylor R.A., Leonard M.C. Curcumin for inflammatory bowel disease: a review of human studies. Altern Med Rev 2011, 16:152-156.
    • (2011) Altern Med Rev , vol.16 , pp. 152-156
    • Taylor, R.A.1    Leonard, M.C.2
  • 10
    • 67649427457 scopus 로고    scopus 로고
    • The effects of dietary curcumin and rutin on colonic inflammation and gene expression in multidrug resistance gene-deficient (mdr1a-/-) mice, a model of inflammatory bowel diseases
    • Nones K., Dommels Y.E., Martell S., Butts C., McNabb W.C., Park Z.A., et al. The effects of dietary curcumin and rutin on colonic inflammation and gene expression in multidrug resistance gene-deficient (mdr1a-/-) mice, a model of inflammatory bowel diseases. Br J Nutr 2009, 101:169-181.
    • (2009) Br J Nutr , vol.101 , pp. 169-181
    • Nones, K.1    Dommels, Y.E.2    Martell, S.3    Butts, C.4    McNabb, W.C.5    Park, Z.A.6
  • 11
    • 0027224059 scopus 로고
    • Clinicopathologic study of dextran sulfate sodium experimental murine colitis
    • Cooper H.S., Murthy S.N., Shah R.S., Sedergran D.J. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 1993, 69:238-249.
    • (1993) Lab Invest , vol.69 , pp. 238-249
    • Cooper, H.S.1    Murthy, S.N.2    Shah, R.S.3    Sedergran, D.J.4
  • 12
    • 0030950114 scopus 로고    scopus 로고
    • Lipid level and type alter stearoyl CoA desaturase mRNA abundance differently in mice with distinct susceptibilities to diet-influenced diseases
    • Park E.I., Paisley E.A., Mangian H.J., Swartz D.A., Wu M.X., O'Morchoe P.J., et al. Lipid level and type alter stearoyl CoA desaturase mRNA abundance differently in mice with distinct susceptibilities to diet-influenced diseases. J Nutr 1997, 127:566-573.
    • (1997) J Nutr , vol.127 , pp. 566-573
    • Park, E.I.1    Paisley, E.A.2    Mangian, H.J.3    Swartz, D.A.4    Wu, M.X.5    O'Morchoe, P.J.6
  • 13
    • 34547661062 scopus 로고    scopus 로고
    • Nutrigenomics applied to an animal model of inflammatory bowel diseases: transcriptomic analysis of the effects of eicosapentaenoic acid- and arachidonic acid-enriched diets
    • Roy N.C., Barnett M.P.G., Knoch B., Dommels Y.E.M., McNabb W.C. Nutrigenomics applied to an animal model of inflammatory bowel diseases: transcriptomic analysis of the effects of eicosapentaenoic acid- and arachidonic acid-enriched diets. Mutat Res 2007, 622:103-116.
    • (2007) Mutat Res , vol.622 , pp. 103-116
    • Roy, N.C.1    Barnett, M.P.G.2    Knoch, B.3    Dommels, Y.E.M.4    McNabb, W.C.5
  • 14
    • 84883771484 scopus 로고    scopus 로고
    • Modulation of colonic inflammation in Mdr1a(-/-) mice by green tea polyphenols and their effects on the colon transcriptome and proteome
    • Barnett M.P., Cooney J.M., Dommels Y.E., Nones K., Brewster D.T., Park Z., et al. Modulation of colonic inflammation in Mdr1a(-/-) mice by green tea polyphenols and their effects on the colon transcriptome and proteome. J Nutr Biochem 2013, 24:1678-1690.
    • (2013) J Nutr Biochem , vol.24 , pp. 1678-1690
    • Barnett, M.P.1    Cooney, J.M.2    Dommels, Y.E.3    Nones, K.4    Brewster, D.T.5    Park, Z.6
  • 16
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B Stat Methodol 1995, 57:289-300.
    • (1995) J R Stat Soc B Stat Methodol , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 17
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R., Domrachev M., Lash A.E. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 2002, 30:207-210.
    • (2002) Nucleic Acids Res , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 18
    • 77955369664 scopus 로고    scopus 로고
    • Molecular characterization of the onset and progression of colitis in inoculated interleukin-10 gene-deficient mice: a role for PPARalpha
    • Knoch B., Barnett M.P., Cooney J., McNabb W.C., Barraclough D., Laing W., et al. Molecular characterization of the onset and progression of colitis in inoculated interleukin-10 gene-deficient mice: a role for PPARalpha. PPAR Res 2010, 2010:621069.
    • (2010) PPAR Res , vol.2010 , pp. 621069
    • Knoch, B.1    Barnett, M.P.2    Cooney, J.3    McNabb, W.C.4    Barraclough, D.5    Laing, W.6
  • 19
    • 0000857494 scopus 로고
    • An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
    • Eng J.K., McCormack A.L., Yates J.R. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom 1994, 5:976-989.
    • (1994) J Am Soc Mass Spectrom , vol.5 , pp. 976-989
    • Eng, J.K.1    McCormack, A.L.2    Yates, J.R.3
  • 20
    • 0029644596 scopus 로고
    • Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database
    • Yates J.R., Eng J.K., McCormack A.L., Schieltz D. Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database. Anal Chem 1995, 67:1426-1436.
    • (1995) Anal Chem , vol.67 , pp. 1426-1436
    • Yates, J.R.1    Eng, J.K.2    McCormack, A.L.3    Schieltz, D.4
  • 21
    • 84894571860 scopus 로고    scopus 로고
    • Causal analysis approaches in Ingenuity Pathway Analysis
    • Kramer A., Green J., Pollard J., Tugendreich S. Causal analysis approaches in Ingenuity Pathway Analysis. Bioinformatics 2014, 30:523-530.
    • (2014) Bioinformatics , vol.30 , pp. 523-530
    • Kramer, A.1    Green, J.2    Pollard, J.3    Tugendreich, S.4
  • 22
    • 0036447117 scopus 로고    scopus 로고
    • Cytokine/chemokine messenger-RNA expression profiles in ulcerative colitis and Crohn's disease
    • Autschbach F., Giese T., Gassler N., Sido B., Heuschen G., Heuschen U., et al. Cytokine/chemokine messenger-RNA expression profiles in ulcerative colitis and Crohn's disease. Virchows Arch 2002, 441:500-513.
    • (2002) Virchows Arch , vol.441 , pp. 500-513
    • Autschbach, F.1    Giese, T.2    Gassler, N.3    Sido, B.4    Heuschen, G.5    Heuschen, U.6
  • 23
    • 77649196117 scopus 로고    scopus 로고
    • Integration of ER stress, oxidative stress and the inflammatory response in health and disease
    • Zhang K. Integration of ER stress, oxidative stress and the inflammatory response in health and disease. Int J Clin Exp Med 2010, 3:33-40.
    • (2010) Int J Clin Exp Med , vol.3 , pp. 33-40
    • Zhang, K.1
  • 24
    • 56749170706 scopus 로고    scopus 로고
    • Lack of macrophage migration inhibitory factor suppresses innate immune response in murine dextran sulfate sodium-induced colitis
    • Ohkawara T., Mitsuyama K., Takeda H., Asaka M., Fujiyama Y., Nishihira J. Lack of macrophage migration inhibitory factor suppresses innate immune response in murine dextran sulfate sodium-induced colitis. Scand J Gastroenterol 2008, 43:1497-1504.
    • (2008) Scand J Gastroenterol , vol.43 , pp. 1497-1504
    • Ohkawara, T.1    Mitsuyama, K.2    Takeda, H.3    Asaka, M.4    Fujiyama, Y.5    Nishihira, J.6
  • 25
    • 34247264918 scopus 로고    scopus 로고
    • Interleukin-6 induces keratin expression in intestinal epithelial cells: potential role of keratin-8 in interleukin-6-induced barrier function alterations
    • Wang L., Srinivasan S., Theiss A.L., Merlin D., Sitaraman S.V. Interleukin-6 induces keratin expression in intestinal epithelial cells: potential role of keratin-8 in interleukin-6-induced barrier function alterations. J Biol Chem 2007, 282:8219-8227.
    • (2007) J Biol Chem , vol.282 , pp. 8219-8227
    • Wang, L.1    Srinivasan, S.2    Theiss, A.L.3    Merlin, D.4    Sitaraman, S.V.5
  • 26
  • 27
    • 57849157341 scopus 로고    scopus 로고
    • Plasma gelsolin as a biomarker of inflammation
    • DiNubile M.J. Plasma gelsolin as a biomarker of inflammation. Arthritis Res Ther 2008, 10:124.
    • (2008) Arthritis Res Ther , vol.10 , pp. 124
    • DiNubile, M.J.1
  • 29
    • 84904088078 scopus 로고    scopus 로고
    • Tumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel disease
    • Ślebioda T.J., Kmieć Z. Tumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel disease. Mediators Inflamm 2014, 2014. 10.1155/2014/325129.
    • (2014) Mediators Inflamm , vol.2014
    • Ślebioda, T.J.1    Kmieć, Z.2
  • 30
    • 70350586944 scopus 로고    scopus 로고
    • Mitogen activated protein kinases: a role in inflammatory bowel disease?
    • Broom O.J., Widjaya B., Troelsen J., Olsen J., Nielsen O.H. Mitogen activated protein kinases: a role in inflammatory bowel disease?. Clin Exp Immunol 2009, 158:272-280.
    • (2009) Clin Exp Immunol , vol.158 , pp. 272-280
    • Broom, O.J.1    Widjaya, B.2    Troelsen, J.3    Olsen, J.4    Nielsen, O.H.5
  • 31
    • 77956165220 scopus 로고    scopus 로고
    • Caught in the Akt: regulation of Wnt signaling in the intestine
    • Anderson E.C., Wong M.H. Caught in the Akt: regulation of Wnt signaling in the intestine. Gastroenterology 2010, 139:718-722.
    • (2010) Gastroenterology , vol.139 , pp. 718-722
    • Anderson, E.C.1    Wong, M.H.2
  • 33
    • 73949145197 scopus 로고    scopus 로고
    • Inhibition of phosphoinositide 3-kinase ameliorates dextran sodium sulfate-induced colitis in mice
    • Peng X.D., Wu X.H., Chen L.J., Wang Z.L., Hu X.H., Song L.F., et al. Inhibition of phosphoinositide 3-kinase ameliorates dextran sodium sulfate-induced colitis in mice. J Pharmacol Exp Ther 2010, 332:46-56.
    • (2010) J Pharmacol Exp Ther , vol.332 , pp. 46-56
    • Peng, X.D.1    Wu, X.H.2    Chen, L.J.3    Wang, Z.L.4    Hu, X.H.5    Song, L.F.6
  • 34
    • 84922380038 scopus 로고    scopus 로고
    • ECM remodelling in IBD: innocent bystander or partner in crime? The emerging role of extracellular molecular events in sustaining intestinal inflammation
    • Shimshoni E., Yablecovitch D., Baram L., Dotan I., Sagi I. ECM remodelling in IBD: innocent bystander or partner in crime? The emerging role of extracellular molecular events in sustaining intestinal inflammation. Gut 2015, 64:367-372.
    • (2015) Gut , vol.64 , pp. 367-372
    • Shimshoni, E.1    Yablecovitch, D.2    Baram, L.3    Dotan, I.4    Sagi, I.5
  • 35
    • 34547092167 scopus 로고    scopus 로고
    • Evidence for a differential expression of fibronectin splice forms ED-A and ED-B in Crohn's disease (CD) mucosa
    • Brenmoehl J., Lang M., Hausmann M., Leeb S.N., Falk W., Scholmerich J., et al. Evidence for a differential expression of fibronectin splice forms ED-A and ED-B in Crohn's disease (CD) mucosa. Int J Colorectal Dis 2007, 22:611-623.
    • (2007) Int J Colorectal Dis , vol.22 , pp. 611-623
    • Brenmoehl, J.1    Lang, M.2    Hausmann, M.3    Leeb, S.N.4    Falk, W.5    Scholmerich, J.6
  • 36
    • 36348939747 scopus 로고    scopus 로고
    • Epithelial-derived fibronectin expression, signaling, and function in intestinal inflammation
    • Kolachala V.L., Bajaj R., Wang L., Yan Y., Ritzenthaler J.D., Gewirtz A.T., et al. Epithelial-derived fibronectin expression, signaling, and function in intestinal inflammation. J Biol Chem 2007, 282:32965-32973.
    • (2007) J Biol Chem , vol.282 , pp. 32965-32973
    • Kolachala, V.L.1    Bajaj, R.2    Wang, L.3    Yan, Y.4    Ritzenthaler, J.D.5    Gewirtz, A.T.6
  • 38
    • 84897985897 scopus 로고    scopus 로고
    • Functional bowel symptoms in quiescent inflammatory bowel diseases: role of epithelial barrier disruption and low-grade inflammation
    • Vivinus-Nebot M., Frin-Mathy G., Bzioueche H., Dainese R., Bernard G., Anty R., et al. Functional bowel symptoms in quiescent inflammatory bowel diseases: role of epithelial barrier disruption and low-grade inflammation. Gut 2014, 63:744-752.
    • (2014) Gut , vol.63 , pp. 744-752
    • Vivinus-Nebot, M.1    Frin-Mathy, G.2    Bzioueche, H.3    Dainese, R.4    Bernard, G.5    Anty, R.6
  • 39
    • 80055108237 scopus 로고    scopus 로고
    • Curcumin augments lung maturation, preventing neonatal lung injury by inhibiting TGF-beta signaling
    • Sakurai R., Li Y., Torday J.S., Rehan V.K. Curcumin augments lung maturation, preventing neonatal lung injury by inhibiting TGF-beta signaling. Am J Physiol Lung Cell Mol Physiol 2011, 301:L721-L730.
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.301 , pp. L721-L730
    • Sakurai, R.1    Li, Y.2    Torday, J.S.3    Rehan, V.K.4
  • 40
    • 45349091414 scopus 로고    scopus 로고
    • Curcumin inhibits NFkappaB mediated radioprotection and modulate apoptosis related genes in human neuroblastoma cells
    • Aravindan N., Madhusoodhanan R., Ahmad S., Johnson D., Herman T.S. Curcumin inhibits NFkappaB mediated radioprotection and modulate apoptosis related genes in human neuroblastoma cells. Cancer Biol Ther 2008, 7:569-576.
    • (2008) Cancer Biol Ther , vol.7 , pp. 569-576
    • Aravindan, N.1    Madhusoodhanan, R.2    Ahmad, S.3    Johnson, D.4    Herman, T.S.5
  • 42
    • 84868684156 scopus 로고    scopus 로고
    • Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations
    • Baliga M.S., Joseph N., Venkataranganna M.V., Saxena A., Ponemone V., Fayad R. Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations. Food Funct 2012, 3:1109-1117.
    • (2012) Food Funct , vol.3 , pp. 1109-1117
    • Baliga, M.S.1    Joseph, N.2    Venkataranganna, M.V.3    Saxena, A.4    Ponemone, V.5    Fayad, R.6
  • 43
    • 59349120231 scopus 로고    scopus 로고
    • Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets
    • Aggarwal B.B., Sung B. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets. Trends Pharmacol Sci 2009, 30:85-94.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 85-94
    • Aggarwal, B.B.1    Sung, B.2
  • 45
    • 77950363955 scopus 로고    scopus 로고
    • Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1beta and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease
    • Epstein J., Docena G., MacDonald T.T., Sanderson I.R. Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1beta and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease. Br J Nutr 2010, 103:824-832.
    • (2010) Br J Nutr , vol.103 , pp. 824-832
    • Epstein, J.1    Docena, G.2    MacDonald, T.T.3    Sanderson, I.R.4
  • 47
    • 79953718477 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor regulates neutrophil chemotactic responses in inflammatory arthritis in mice
    • Santos L.L., Fan H., Hall P., Ngo D., Mackay C.R., Fingerle-Rowson G., et al. Macrophage migration inhibitory factor regulates neutrophil chemotactic responses in inflammatory arthritis in mice. Arthritis Rheum 2011, 63:960-970.
    • (2011) Arthritis Rheum , vol.63 , pp. 960-970
    • Santos, L.L.1    Fan, H.2    Hall, P.3    Ngo, D.4    Mackay, C.R.5    Fingerle-Rowson, G.6
  • 48
    • 77958561665 scopus 로고    scopus 로고
    • Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-kappaB activation
    • Song W.B., Wang Y.Y., Meng F.S., Zhang Q.H., Zeng J.Y., Xiao L.P., et al. Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-kappaB activation. PLoS One 2010, 5:e12969.
    • (2010) PLoS One , vol.5 , pp. e12969
    • Song, W.B.1    Wang, Y.Y.2    Meng, F.S.3    Zhang, Q.H.4    Zeng, J.Y.5    Xiao, L.P.6
  • 49
    • 77957278004 scopus 로고    scopus 로고
    • Cytoskeletal regulation of epithelial barrier function during inflammation
    • Ivanov A.I., Parkos C.A., Nusrat A. Cytoskeletal regulation of epithelial barrier function during inflammation. Am J Pathol 2010, 177:512-524.
    • (2010) Am J Pathol , vol.177 , pp. 512-524
    • Ivanov, A.I.1    Parkos, C.A.2    Nusrat, A.3
  • 50
    • 65049088214 scopus 로고    scopus 로고
    • Curcumin, a nutritional supplement with antineoplastic activity, enhances leiomyoma cell apoptosis and decreases fibronectin expression
    • Malik M., Mendoza M., Payson M., Catherino W.H. Curcumin, a nutritional supplement with antineoplastic activity, enhances leiomyoma cell apoptosis and decreases fibronectin expression. Fertil Steril 2009, 91:2177-2184.
    • (2009) Fertil Steril , vol.91 , pp. 2177-2184
    • Malik, M.1    Mendoza, M.2    Payson, M.3    Catherino, W.H.4
  • 51
    • 33645803853 scopus 로고    scopus 로고
    • Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factor
    • Zheng S., Chen A. Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factor. Am J Physiol Gastrointest Liver Physiol 2006, 290:G883-G893.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , pp. G883-G893
    • Zheng, S.1    Chen, A.2
  • 52
    • 0036108620 scopus 로고    scopus 로고
    • Cadherin and catenin alterations in human cancer
    • Hajra K.M., Fearon E.R. Cadherin and catenin alterations in human cancer. Genes Chromosomes Cancer 2002, 34:255-268.
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 255-268
    • Hajra, K.M.1    Fearon, E.R.2
  • 53
    • 84859868412 scopus 로고    scopus 로고
    • Curcumin attenuates beta-catenin signaling in prostate cancer cells through activation of protein kinase D1
    • Sundram V., Chauhan S.C., Ebeling M., Jaggi M. Curcumin attenuates beta-catenin signaling in prostate cancer cells through activation of protein kinase D1. PLoS One 2012, 7:e35368.
    • (2012) PLoS One , vol.7 , pp. e35368
    • Sundram, V.1    Chauhan, S.C.2    Ebeling, M.3    Jaggi, M.4
  • 55
    • 33750520736 scopus 로고    scopus 로고
    • Curcumin regulates signal transducer and activator of transcription (STAT) expression in K562 cells
    • Blasius R., Reuter S., Henry E., Dicato M., Diederich M. Curcumin regulates signal transducer and activator of transcription (STAT) expression in K562 cells. Biochem Pharmacol 2006, 72:1547-1554.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1547-1554
    • Blasius, R.1    Reuter, S.2    Henry, E.3    Dicato, M.4    Diederich, M.5
  • 56
    • 0345016388 scopus 로고    scopus 로고
    • Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia
    • Kim H.Y., Park E.J., Joe E.H., Jou I. Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia. J Immunol 2003, 171:6072-6079.
    • (2003) J Immunol , vol.171 , pp. 6072-6079
    • Kim, H.Y.1    Park, E.J.2    Joe, E.H.3    Jou, I.4
  • 57
    • 34248205135 scopus 로고    scopus 로고
    • Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy
    • Bisht S., Feldmann G., Soni S., Ravi R., Karikar C., Maitra A., et al. Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy. J Nanobiotechnol 2007, 5:3.
    • (2007) J Nanobiotechnol , vol.5 , pp. 3
    • Bisht, S.1    Feldmann, G.2    Soni, S.3    Ravi, R.4    Karikar, C.5    Maitra, A.6
  • 59
    • 84952869386 scopus 로고    scopus 로고
    • A neutraceutical by design: the clinical application of curcumin in colonic inflammation and cancer
    • Soni D., Salh B. A neutraceutical by design: the clinical application of curcumin in colonic inflammation and cancer. Scientifica (Cairo) 2012, 2012:757890.
    • (2012) Scientifica (Cairo) , vol.2012 , pp. 757890
    • Soni, D.1    Salh, B.2
  • 60
    • 77953625233 scopus 로고    scopus 로고
    • Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhance its antioxidant and antihepatoma activities
    • Yen F.L., Wu T.H., Tzeng C.W., Lin L.T., Lin C.C. Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhance its antioxidant and antihepatoma activities. J Agric Food Chem 2010, 58:7376-7382.
    • (2010) J Agric Food Chem , vol.58 , pp. 7376-7382
    • Yen, F.L.1    Wu, T.H.2    Tzeng, C.W.3    Lin, L.T.4    Lin, C.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.