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Volumn 13, Issue 1, 2016, Pages

Interleukin-18 modulation in autism spectrum disorders

Author keywords

Autism; Cytokines; ELISA; IL 18; Immunohistochemistry; Reeler mice

Indexed keywords

INTERLEUKIN 18; INTERLEUKIN 18 BINDING PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CYTOKINE; INTERLEUKIN-18 BINDING PROTEIN; SIGNAL PEPTIDE;

EID: 84952837227     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0466-6     Document Type: Article
Times cited : (28)

References (53)
  • 1
    • 79751486175 scopus 로고    scopus 로고
    • Theoretical aspects of autism: causes-a review
    • Ratacczak HV. Theoretical aspects of autism: causes-a review. J Immunotoxicol. 2011;8:68-79. doi: 10.1192/bjp.bp.108.059345.
    • (2011) J Immunotoxicol , vol.8 , pp. 68-79
    • Ratacczak, H.V.1
  • 3
    • 84894535084 scopus 로고    scopus 로고
    • Inflammation in children and adolescents with neuropsychiatric disorders: a systematic review
    • Mitchell RH, Goldstein BI. Inflammation in children and adolescents with neuropsychiatric disorders: a systematic review. J Am Acad Child Adolesc Psychiatry. 2014;53:274-96. doi: 10.1016/j.jaac.2013.11.013.
    • (2014) J Am Acad Child Adolesc Psychiatry , vol.53 , pp. 274-296
    • Mitchell, R.H.1    Goldstein, B.I.2
  • 4
    • 84893675645 scopus 로고    scopus 로고
    • Immune dysregulation in autism spectrum disorder
    • Noriega DB, Savelkoul HF. Immune dysregulation in autism spectrum disorder. Eur J Pediatr. 2014;173:33-43. doi: 10.1007/s00431-013-2183-4.
    • (2014) Eur J Pediatr , vol.173 , pp. 33-43
    • Noriega, D.B.1    Savelkoul, H.F.2
  • 5
    • 84862188749 scopus 로고    scopus 로고
    • Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders
    • Garay PA, McAllister AK. Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders. Front SynapticNeurosci. 2010;8(2):136. doi: 10.3389/fnsyn.2010.00136.
    • (2010) Front SynapticNeurosci , vol.8 , Issue.2 , pp. 136
    • Garay, P.A.1    McAllister, A.K.2
  • 6
    • 84937641555 scopus 로고    scopus 로고
    • Role of microglia in autism: recent advances
    • Takano T. Role of microglia in autism: recent advances. Dev Neurosci. 2015;37:195-202. doi: 10.1159/000398791.
    • (2015) Dev Neurosci , vol.37 , pp. 195-202
    • Takano, T.1
  • 7
    • 84937558111 scopus 로고    scopus 로고
    • Immune mediators in the brain and peripheral tissues in autism spectrum disorder
    • Estes ML, McAllister AK. Immune mediators in the brain and peripheral tissues in autism spectrum disorder. Nat Rev Neurosci. 2015;16:469-86. doi: 10.1038/nrn3978.
    • (2015) Nat Rev Neurosci , vol.16 , pp. 469-486
    • Estes, M.L.1    McAllister, A.K.2
  • 8
    • 84878767675 scopus 로고    scopus 로고
    • IL-1β and TNF-aα induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase
    • Ye L, Huang Y, Zhao L, Li Y, Sun L, Zhou Y, et al. IL-1β and TNF-aα induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase. J Neurochem. 2013;125:897-908. doi: 10.1111/jnc.12263.
    • (2013) J Neurochem , vol.125 , pp. 897-908
    • Ye, L.1    Huang, Y.2    Zhao, L.3    Li, Y.4    Sun, L.5    Zhou, Y.6
  • 10
    • 0036498510 scopus 로고    scopus 로고
    • Cytokine-induced sickness behaviour: mechanisms and implications
    • Konsman JP, Parnet P, Dantzer R. Cytokine-induced sickness behaviour: mechanisms and implications. Trends Neurosci. 2002;25:154-9.
    • (2002) Trends Neurosci , vol.25 , pp. 154-159
    • Konsman, J.P.1    Parnet, P.2    Dantzer, R.3
  • 11
    • 84855777698 scopus 로고    scopus 로고
    • Stress-induced cytokines and neuronal dysfunction in Alzheimer's disease
    • Ricci S, Fuso A, Ippoliti F, Businaro R. Stress-induced cytokines and neuronal dysfunction in Alzheimer's disease. J Alzheimers Dis. 2012;28:11-24. doi: 10.3233/JAD-2011-110821.
    • (2012) J Alzheimers Dis , vol.28 , pp. 11-24
    • Ricci, S.1    Fuso, A.2    Ippoliti, F.3    Businaro, R.4
  • 12
    • 84873322584 scopus 로고    scopus 로고
    • Peripheral and central inflammation in autism spectrum disorders
    • Depino AM. Peripheral and central inflammation in autism spectrum disorders. Mol Cell Neurosci. 2013;53:69-76. doi: 10.1016/j.mcn.2012.10.003.
    • (2013) Mol Cell Neurosci , vol.53 , pp. 69-76
    • Depino, A.M.1
  • 14
    • 84892867717 scopus 로고    scopus 로고
    • Interleukin-18, more than a Th1 cytokine
    • Novick D, Kim S, Kaplanski G, Dinarello CA. Interleukin-18, more than a Th1 cytokine. Semin Immunol. 2013;25:439-48. doi: 10.1016/j.smim.2013.10.014.
    • (2013) Semin Immunol , vol.25 , pp. 439-448
    • Novick, D.1    Kim, S.2    Kaplanski, G.3    Dinarello, C.A.4
  • 16
    • 57849144282 scopus 로고    scopus 로고
    • Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients
    • Ojala J, Alafuzoff I, Herukka SK, van Groen T, Tanila H, Pirttilä T. Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients. Neurobiol Aging. 2009;30:198-209. doi: 10.1016/j.neurobiolaging.2007.06.006.
    • (2009) Neurobiol Aging , vol.30 , pp. 198-209
    • Ojala, J.1    Alafuzoff, I.2    Herukka, S.K.3    Groen, T.4    Tanila, H.5    Pirttilä, T.6
  • 17
    • 84864958598 scopus 로고    scopus 로고
    • Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cells
    • Sutinen EM, Pirttilä T, Anderson G, Salminen A, Ojala JO. Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cells. J Neuroinflammation. 2012;9:199. doi: 10.1186/1742-2094-9-199.
    • (2012) J Neuroinflammation , vol.9 , pp. 199
    • Sutinen, E.M.1    Pirttilä, T.2    Anderson, G.3    Salminen, A.4    Ojala, J.O.5
  • 18
    • 84905675710 scopus 로고    scopus 로고
    • Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells
    • Sutinen EM, Korolainen MA, Häyrinen J, Alafuzoff I, Petratos S, Salminen A, et al. Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells. Front Cell Neurosci. 2014;8:214. doi: 10.3389/fncel.2014.00214.
    • (2014) Front Cell Neurosci , vol.8 , pp. 214
    • Sutinen, E.M.1    Korolainen, M.A.2    Häyrinen, J.3    Alafuzoff, I.4    Petratos, S.5    Salminen, A.6
  • 19
    • 84879434002 scopus 로고    scopus 로고
    • Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precursor protein, striatal-enriched proteintyrosine phosphatase, and homer 1, in autism: a postmortem study in cerebellar vermis and superior frontal cortex
    • Fatemi SH, Folsom TD, Kneeland RE, Yousefi MK, Liesch SB, Thuras PD. Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precursor protein, striatal-enriched proteintyrosine phosphatase, and homer 1, in autism: a postmortem study in cerebellar vermis and superior frontal cortex. Mol Autism. 2013;4:21. doi: 10.1186/2040-2392-4-21.
    • (2013) Mol Autism , vol.4 , pp. 21
    • Fatemi, S.H.1    Folsom, T.D.2    Kneeland, R.E.3    Yousefi, M.K.4    Liesch, S.B.5    Thuras, P.D.6
  • 20
    • 33746096547 scopus 로고    scopus 로고
    • Paradoxical effects of prenatal acetylcholinesterase blockade on neuro-behavioral development and drug-induced stereotypies in reeler mutant mice
    • Laviola G, Adriani W, Gaudino C, Marino R, Keller F. Paradoxical effects of prenatal acetylcholinesterase blockade on neuro-behavioral development and drug-induced stereotypies in reeler mutant mice. Psychopharmacology (Berl). 2006;187:331-44. doi: 10.1007/s00213-006-0426-z.
    • (2006) Psychopharmacology (Berl) , vol.187 , pp. 331-344
    • Laviola, G.1    Adriani, W.2    Gaudino, C.3    Marino, R.4    Keller, F.5
  • 23
    • 0642369555 scopus 로고    scopus 로고
    • The neurobiological context of autism
    • Keller F, Persico AM. The neurobiological context of autism. Mol Neurobiol. 2003;28:1-22. doi: 10.1385/MN:28:1:1.
    • (2003) Mol Neurobiol , vol.28 , pp. 1-22
    • Keller, F.1    Persico, A.M.2
  • 24
    • 84875648076 scopus 로고    scopus 로고
    • Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment
    • Goines PE, Ashwood P. Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment. Neurotoxicol Teratol. 2013;36:67-81. doi: 10.1016/j.ntt.2012.07.006.
    • (2013) Neurotoxicol Teratol , vol.36 , pp. 67-81
    • Goines, P.E.1    Ashwood, P.2
  • 25
    • 82255192290 scopus 로고    scopus 로고
    • The conundrums of understanding genetic risks for autism spectrum disorders
    • State MW, Levitt P. The conundrums of understanding genetic risks for autism spectrum disorders. Nat Neurosci. 2011;14:1499-506. doi: 10.1016/j.ntt.2012.07.006.
    • (2011) Nat Neurosci , vol.14 , pp. 1499-1506
    • State, M.W.1    Levitt, P.2
  • 26
    • 84888097026 scopus 로고    scopus 로고
    • Converging pathways in autism spectrum disorders: interplay between synaptic dysfunction and immune responses
    • Voineagu I, Eapen V. Converging pathways in autism spectrum disorders: interplay between synaptic dysfunction and immune responses. Front Hum Neurosci. 2013;7:738. doi: 10.3389/fnhum.2013.00738.
    • (2013) Front Hum Neurosci , vol.7 , pp. 738
    • Voineagu, I.1    Eapen, V.2
  • 27
    • 80052633284 scopus 로고    scopus 로고
    • Synaptic pruning by microglia is necessary for normal brain development
    • Paolicelli RC, Bolasco G, Pagani F, Maggi L, Scianni M, Panzanelli P, et al. Synaptic pruning by microglia is necessary for normal brain development. Science. 2011;333(6048):1456-8. doi: 10.1126/science.1202529.
    • (2011) Science , vol.333 , Issue.6048 , pp. 1456-1458
    • Paolicelli, R.C.1    Bolasco, G.2    Pagani, F.3    Maggi, L.4    Scianni, M.5    Panzanelli, P.6
  • 28
    • 84857190395 scopus 로고    scopus 로고
    • The role of immune dysfunction in the pathophysiology of autism
    • Onore C, Careaga M, Ashwood P. The role of immune dysfunction in the pathophysiology of autism. Brain Behav Immun. 2012;26:383-92. doi: 10.1016/j.bbi.2011.08.007.
    • (2012) Brain Behav Immun , vol.26 , pp. 383-392
    • Onore, C.1    Careaga, M.2    Ashwood, P.3
  • 29
    • 84913529177 scopus 로고    scopus 로고
    • Evidence supporting an altered immune response in ASD
    • Mead J, Ashwood P. Evidence supporting an altered immune response in ASD. Immunol Lett. 2015;163:49-55. doi: 10.1016/j.imlet.2014.11.006.
    • (2015) Immunol Lett , vol.163 , pp. 49-55
    • Mead, J.1    Ashwood, P.2
  • 30
    • 35448979876 scopus 로고    scopus 로고
    • Altered plasma cytokine levels in Alzheimer's disease: correlation with the disease progression
    • Motta M, Imbesi R, Di Rosa M, Stivala F, Malaguarnera L. Altered plasma cytokine levels in Alzheimer's disease: correlation with the disease progression. Immunol Lett. 2007;114:46-51. doi: 10.1016/j.imlet.2007.09.002.
    • (2007) Immunol Lett , vol.114 , pp. 46-51
    • Motta, M.1    Imbesi, R.2    Rosa, M.3    Stivala, F.4    Malaguarnera, L.5
  • 31
    • 84857504095 scopus 로고    scopus 로고
    • A novel study on amyloid β peptide 40, 42 and 40/42 ratio in Saudi autistics
    • Al-Ayadhi LY, Ben Bacha AG, Kotb M, El-Ansary AK. A novel study on amyloid β peptide 40, 42 and 40/42 ratio in Saudi autistics. Behav Brain Funct. 2012;8:4. doi: 10.1186/1744-9081-8-4.
    • (2012) Behav Brain Funct , vol.8 , pp. 4
    • Al-Ayadhi, L.Y.1    Ben Bacha, A.G.2    Kotb, M.3    El-Ansary, A.K.4
  • 32
    • 80053984642 scopus 로고    scopus 로고
    • Proinflammatory and proapoptotic markers in relation to mono and di-cations in plasma of autistic patients from Saudi Arabia
    • El-Ansary AK, Ben Bacha AG, Al-Ayadhi LY. Proinflammatory and proapoptotic markers in relation to mono and di-cations in plasma of autistic patients from Saudi Arabia. J Neuroinflammation. 2011;8:142. doi: 10.1186/1742-2094-8-142.
    • (2011) J Neuroinflammation , vol.8 , pp. 142
    • El-Ansary, A.K.1    Ben Bacha, A.G.2    Al-Ayadhi, L.Y.3
  • 33
    • 60149103359 scopus 로고    scopus 로고
    • Elevated immune response in the brain of autistic patients
    • Li X, Chauhan A, Sheikh AM, Patil S, Chauhan V, Li XM, et al. Elevated immune response in the brain of autistic patients. J Neuroimmunol. 2009;207:111-6. doi: 10.1016/j.jneuroim.2008.12.002.
    • (2009) J Neuroimmunol , vol.207 , pp. 111-116
    • Li, X.1    Chauhan, A.2    Sheikh, A.M.3    Patil, S.4    Chauhan, V.5    Li, X.M.6
  • 34
    • 69949179196 scopus 로고    scopus 로고
    • Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain
    • Alboni S, Cervia D, Ross B, Montanari C, Gonzalez AS, Sanchez-Alavez M, et al. Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain. J Neuroimmunol. 2009;214:43-54. doi: 10.1016/j.jneuroim.2009.06.016.
    • (2009) J Neuroimmunol , vol.214 , pp. 43-54
    • Alboni, S.1    Cervia, D.2    Ross, B.3    Montanari, C.4    Gonzalez, A.S.5    Sanchez-Alavez, M.6
  • 35
    • 0344872725 scopus 로고    scopus 로고
    • Identification of a truncated IL-18R beta mRNA: a putative regulator of IL-18 expressed in rat brain
    • Andre R, Wheeler RD, Collins PD, Luheshi GN, Pickering-Brown S, Kimber I, et al. Identification of a truncated IL-18R beta mRNA: a putative regulator of IL-18 expressed in rat brain. J Neuroimmunol. 2003;145:40-5. http://dx.doi.org/10.1016/j.jneuroim.2003.09.005
    • (2003) J Neuroimmunol , vol.145 , pp. 40-45
    • Andre, R.1    Wheeler, R.D.2    Collins, P.D.3    Luheshi, G.N.4    Pickering-Brown, S.5    Kimber, I.6
  • 36
    • 45549096896 scopus 로고    scopus 로고
    • Interleukin-18 and stress
    • Sugama S, Conti B. Interleukin-18 and stress. Brain Res Rev. 2008;58:85-95. doi: 10.1016/j.brainresrev.2007.11.003.
    • (2008) Brain Res Rev , vol.58 , pp. 85-95
    • Sugama, S.1    Conti, B.2
  • 37
    • 35348995490 scopus 로고    scopus 로고
    • Identification of IL-18RAP mRNA truncated splice variants in human testis and the other human tissues
    • Fiszer D, Rozwadowska N, Rychlewski L, Kosicki W, Kurpisz M. Identification of IL-18RAP mRNA truncated splice variants in human testis and the other human tissues. Cytokine. 2007;39:178-83. doi: 10.1016/j.cyto.2007.07.186.
    • (2007) Cytokine , vol.39 , pp. 178-183
    • Fiszer, D.1    Rozwadowska, N.2    Rychlewski, L.3    Kosicki, W.4    Kurpisz, M.5
  • 38
    • 56349125650 scopus 로고    scopus 로고
    • Interleukin-18 increases expression of kinases involved in tau phosphorylation in SH-SY5Y neuroblastoma cells
    • Ojala JO, Sutinen EM, Salminen A, Pirttilä T. Interleukin-18 increases expression of kinases involved in tau phosphorylation in SH-SY5Y neuroblastoma cells. J Neuroimmunol. 2008;205:86-93. doi: 10.1016/j.jneuroim.2008.09.012.
    • (2008) J Neuroimmunol , vol.205 , pp. 86-93
    • Ojala, J.O.1    Sutinen, E.M.2    Salminen, A.3    Pirttilä, T.4
  • 39
    • 70350185424 scopus 로고    scopus 로고
    • Interleukin-18 regulates motor activity, anxiety and spatial learning without affecting synaptic plasticity
    • Yaguchi T, Nagata T, Yang D, Nishizaki T. Interleukin-18 regulates motor activity, anxiety and spatial learning without affecting synaptic plasticity. Behav Brain Res. 2010;206:47-51. doi: 10.1016/j.bbr.2009.08.033.
    • (2010) Behav Brain Res , vol.206 , pp. 47-51
    • Yaguchi, T.1    Nagata, T.2    Yang, D.3    Nishizaki, T.4
  • 40
    • 58149391974 scopus 로고    scopus 로고
    • Interleukin-18-mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury
    • Miyoshi K, Obata K, Kondo T, Okamura H, Noguchi K. Interleukin-18-mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury. J Neurosci. 2008;28:12775-87. doi: 10.1523/JNEUROSCI.3512-08.2008.
    • (2008) J Neurosci , vol.28 , pp. 12775-12787
    • Miyoshi, K.1    Obata, K.2    Kondo, T.3    Okamura, H.4    Noguchi, K.5
  • 41
    • 0034853483 scopus 로고    scopus 로고
    • IL-18 in patients with multiple sclerosis
    • Losy J, Niezgoda A. IL-18 in patients with multiple sclerosis. Acta Neurol Scand. 2001;104:171-3. doi: 10.1034/j.1600-0404.2001.00356.x.
    • (2001) Acta Neurol Scand , vol.104 , pp. 171-173
    • Losy, J.1    Niezgoda, A.2
  • 42
    • 42049111225 scopus 로고    scopus 로고
    • The diagnostic role of serum inflammatory and soluble proteins on dementia subtypes: correlation with cognitive and functional decline
    • Oztürk C, Ozge A, Yalin OO, Yilmaz IA, Delialioglu N, Yildiz C, et al. The diagnostic role of serum inflammatory and soluble proteins on dementia subtypes: correlation with cognitive and functional decline. Behav Neurol. 2007;18:207-15.
    • (2007) Behav Neurol , vol.18 , pp. 207-215
    • Oztürk, C.1    Ozge, A.2    Yalin, O.O.3    Yilmaz, I.A.4    Delialioglu, N.5    Yildiz, C.6
  • 43
    • 34249674445 scopus 로고    scopus 로고
    • A role for inflammatory mediators in the IL-18 mediated attenuation of LTP in the rat dentate gyrus
    • Cumiskey D, Curran BP, Herron CE, O'Connor JJ. A role for inflammatory mediators in the IL-18 mediated attenuation of LTP in the rat dentate gyrus. Neuropharmacology. 2007;52:1616-23. doi: 10.1016/j.neuropharm.2007.03.006.
    • (2007) Neuropharmacology , vol.52 , pp. 1616-1623
    • Cumiskey, D.1    Curran, B.P.2    Herron, C.E.3    O'Connor, J.J.4
  • 44
    • 79960574244 scopus 로고    scopus 로고
    • Aberrant immune responses in a mouse with behavioral disorders
    • Heo Y, Zhang Y, Gao D, Miller VM, Lawrence DA. Aberrant immune responses in a mouse with behavioral disorders. PLoS One. 2011;6:e20912. doi: 10.1371/journal.pone.0020912.
    • (2011) PLoS One , vol.6 , pp. e20912
    • Heo, Y.1    Zhang, Y.2    Gao, D.3    Miller, V.M.4    Lawrence, D.A.5
  • 45
    • 0028845730 scopus 로고
    • Cloning of a new cytokine that induces IFN-gamma production by T cells
    • Okamura H, Tsutsi H, Komatsu T, Yutsudo M, Hakura A, Tanimoto T, et al. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature. 1995;378:88-91. doi: 10.1038/378088a0.
    • (1995) Nature , vol.378 , pp. 88-91
    • Okamura, H.1    Tsutsi, H.2    Komatsu, T.3    Yutsudo, M.4    Hakura, A.5    Tanimoto, T.6
  • 46
    • 0037331297 scopus 로고    scopus 로고
    • Association of interleukin-18 expression with enhanced levels of both interleukin-1beta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis
    • Joosten LA, Radstake TR, Lubberts E, van den Bersselaar LA, van Riel PL, van Lent PL, et al. Association of interleukin-18 expression with enhanced levels of both interleukin-1beta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis. Arthritis Rheum. 2003;48:339-47. doi: 10.1002/art.10814.
    • (2003) Arthritis Rheum , vol.48 , pp. 339-347
    • Joosten, L.A.1    Radstake, T.R.2    Lubberts, E.3    Bersselaar, L.A.4    Riel, P.L.5    Lent, P.L.6
  • 47
    • 34548086786 scopus 로고    scopus 로고
    • HPA and immune axes in stress: involvement of the serotonergic system
    • Leonard BE. HPA and immune axes in stress: involvement of the serotonergic system. Neuroimmunomodulation. 2006;13:268-76. doi: 10.1159/000104854.
    • (2006) Neuroimmunomodulation , vol.13 , pp. 268-276
    • Leonard, B.E.1
  • 48
    • 77958068373 scopus 로고    scopus 로고
    • The concept of depression as a dysfunction of the immune system
    • Leonard BE. The concept of depression as a dysfunction of the immune system. Curr Immunol Rev. 2010;6:205-12. doi: 10.2174/157339510791823835.
    • (2010) Curr Immunol Rev , vol.6 , pp. 205-212
    • Leonard, B.E.1
  • 49
    • 79954585088 scopus 로고    scopus 로고
    • Alzheimer's and seizures: interleukin-18, indoleamine 2,3-dioxygenase and quinolinic Acid
    • Anderson G, Ojala J. Alzheimer's and seizures: interleukin-18, indoleamine 2,3-dioxygenase and quinolinic Acid. Int J Tryptophan Res. 2010;3:169-73. doi: 10.4137/IJTR.S4603.
    • (2010) Int J Tryptophan Res , vol.3 , pp. 169-173
    • Anderson, G.1    Ojala, J.2
  • 51
    • 79959333777 scopus 로고    scopus 로고
    • A lack of association between hyperserotonemia and the increased frequency of serum anti-myelin basic protein auto-antibodies in autistic children
    • Mostafa GA, Al-Ayadhi LY. A lack of association between hyperserotonemia and the increased frequency of serum anti-myelin basic protein auto-antibodies in autistic children. J Neuroinflammation. 2011;8:71. doi: 10.1186/1742-2094-8-71.
    • (2011) J Neuroinflammation , vol.8 , pp. 71
    • Mostafa, G.A.1    Al-Ayadhi, L.Y.2
  • 52
    • 4944240550 scopus 로고    scopus 로고
    • Serotonin in autism and pediatric epilepsies
    • Chugani DC. Serotonin in autism and pediatric epilepsies. Ment Retard Dev Disabil Res Rev. 2004;10:112-6.
    • (2004) Ment Retard Dev Disabil Res Rev , vol.10 , pp. 112-116
    • Chugani, D.C.1
  • 53
    • 36949030449 scopus 로고    scopus 로고
    • Glial expression of interleukin-18 and its receptor after excitotoxic damage in the mouse hippocampus
    • Jeon GS, Park SK, Park SW, Kim DW, Chung CK, Cho SS. Glial expression of interleukin-18 and its receptor after excitotoxic damage in the mouse hippocampus. Neurochem Res. 2008;33:179-84. doi: 10.1007/s11064-007-9434-6.
    • (2008) Neurochem Res , vol.33 , pp. 179-184
    • Jeon, G.S.1    Park, S.K.2    Park, S.W.3    Kim, D.W.4    Chung, C.K.5    Cho, S.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.