Somatic mutation screening using archival formalin-fixed, paraffin-embedded tissues by fluidigm multiplex PCR and illumina sequencing

Journal of Molecular Diagnostics

Volumn 17, Issue 5, 2015, Pages 521-532

  Wang, Ming ^a   Escudero Ibarz, Leire ^a   Moody, Sarah ^a   Zeng, Naiyan ^a   Clipson, Alexandra ^a   Huang, Yuanxue ^a   Xue, Xuemin ^a   Grigoropoulos, Nicholas F ^a   Barrans, Sharon ^b   Worrillow, Lisa ^b   Forshew, Tim ^a   Su, Jing ^a   Firth, Andrew ^a   Martin, Howard ^c   Jack, Andrew ^b   Brugger, Kim ^c   Du, Ming Qing ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b St James's Institute of Oncology   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; FORMALDEHYDE; PARAFFIN; TAQ POLYMERASE;

ALGORITHM; ARTICLE; CANCER PATIENT; CANCER TISSUE; CONTROLLED STUDY; DIAGNOSTIC KIT; DIAGNOSTIC TEST ACCURACY STUDY; DNA DEGRADATION; EMBEDDING; FALSE POSITIVE RESULT; FORMALIN FIXED PARAFFIN EMBEDDED TISSUE; GENE; GENE DUPLICATION; GENE FREQUENCY; HIGH THROUGHPUT SCREENING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INDEL MUTATION; LARGE CELL LYMPHOMA; MAJOR CLINICAL STUDY; MOLECULAR WEIGHT; MULTIPLEX POLYMERASE CHAIN REACTION; NEXT GENERATION SEQUENCING; PREDICTIVE VALUE; SANGER SEQUENCING; SEQUENCE ANALYSIS; SOMATIC MUTATION; SPLENIC MARGINAL ZONE LYMPHOMA; SUBSTITUTION LINE; TISSUE SECTION; AMINO ACID SUBSTITUTION; CHEMISTRY; DEVICES; DNA MUTATIONAL ANALYSIS; EVALUATION STUDY; GENETIC SCREENING; GENETICS; HIGH THROUGHPUT SEQUENCING; LYMPHOMA; PATHOLOGY; PROCEDURES; TISSUE FIXATION;

ALGORITHMS; AMINO ACID SUBSTITUTION; DNA MUTATIONAL ANALYSIS; FALSE POSITIVE REACTIONS; FORMALDEHYDE; GENETIC TESTING; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INDEL MUTATION; LYMPHOMA; MULTIPLEX POLYMERASE CHAIN REACTION; PARAFFIN EMBEDDING; TISSUE FIXATION;

EID: 84952654237     PISSN: 15251578     EISSN: 19437811     Source Type: Journal    
DOI: 10.1016/j.jmoldx.2015.04.008     Document Type: Article

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