Discovery of bicyclic inhibitors against menaquinone biosynthesis

Future Medicinal Chemistry

Volumn 8, Issue 1, 2016, Pages 11-16

  Choi, Seoung Ryoung ^a   Larson, Marilynn A ^a   Hinrichs, Steven H ^a   Bartling, Amanda M ^a   Frandsen, Joel ^a   Narayanasamy, Prabagaran ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 NAPHTHOL; 7 METHOXY 2 NAPHTHOL; ANTIBIOTIC AGENT; MENAQUINONE; UNCLASSIFIED DRUG; 1,4-DIHYDROXY-2-NAPHTHOATE PRENYLTRANSFERASE, MYCOBACTERIUM TUBERCULOSIS; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BICYCLO COMPOUND; ENZYME INHIBITOR; FARNOQUINONE; NAPHTHALENE DERIVATIVE; TRANSFERASE;

ARTICLE; BIOSYNTHESIS; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; SYNTHESIS; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG DEVELOPMENT; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; STRUCTURE ACTIVITY RELATION;

ALKYL AND ARYL TRANSFERASES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BICYCLO COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; ENZYME INHIBITORS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; NAPHTHALENES; STRUCTURE-ACTIVITY RELATIONSHIP; VITAMIN K 2;

EID: 84952648443     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc.15.168     Document Type: Article

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