Diarachidonoylphosphoethanolamine induces apoptosis of malignant pleural mesothelioma cells through a Trx/ASK1/p38 MAPK pathway

Journal of Pharmacological Sciences

Volumn 129, Issue 3, 2015, Pages 160-168

  Tsuchiya, Ayako ^a   Kaku, Yoshiko ^a   Nakano, Takashi ^a   Nishizaki, Tomoyuki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

1,2 Diarachidonoyl sn glycero 3 phosphoethanolamine; Apoptosis signal regulating kinase 1; p38 Mitogen activated protein kinase; Reactive oxygen species; Thioredoxin

Indexed keywords

ANTIOXIDANT; APOPTOSIS SIGNAL REGULATING KINASE 1; DIARACHIDONOYLPHOSPHOETHANOLAMINE; GLUTATHIONE TRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOETHANOLAMINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THIOREDOXIN; THIOREDOXIN REDUCTASE; THIOREDOXIN REDUCTASE 1; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 1,2-DIARACHIDONOYL-GLYCERO-3-PHOSPHOETHANOLAMINE; MAP3K5 PROTEIN, HUMAN; PHOSPHATIDYLETHANOLAMINE; TXN PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CHROMOSOME ABERRATION; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MTT ASSAY; NECROPTOSIS; NECROSIS; PLEURA MESOTHELIOMA; TUNEL ASSAY; WESTERN BLOTTING; DRUG EFFECTS; GENETICS; LUNG TUMOR; MESOTHELIOMA; METABOLISM; PATHOLOGY; PHYSIOLOGY; PLEURA TUMOR; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

APOPTOSIS; HUMANS; LUNG NEOPLASMS; MAP KINASE KINASE KINASE 5; MAP KINASE SIGNALING SYSTEM; MESOTHELIOMA; NADPH OXIDASE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLETHANOLAMINES; PLEURAL NEOPLASMS; REACTIVE OXYGEN SPECIES; THIOREDOXINS; TUMOR CELLS, CULTURED;

EID: 84952638860     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1016/j.jphs.2015.10.003     Document Type: Article

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