메뉴 건너뛰기




Volumn 17, Issue 1, 2012, Pages 40-47

Pathological and molecular biological approaches to early mesothelioma

Author keywords

Atypical mesothelial proliferation; Mesothelioma; Mesothelioma in situ; p16 INK4a p14 ARF (CDKN2A); Reactive mesothelial hyperplasia

Indexed keywords

BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 2A; MERLIN; BAP1 PROTEIN, HUMAN; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN THIOLESTERASE;

EID: 84862232824     PISSN: 13419625     EISSN: 14377772     Source Type: Journal    
DOI: 10.1007/s10147-011-0369-1     Document Type: Review
Times cited : (19)

References (69)
  • 2
    • 26444458845 scopus 로고    scopus 로고
    • Advances in malignant meso-thelioma
    • Robinson BW, Lake RA (2005) Advances in malignant meso-thelioma. N Engl J Med 353:1591-1603
    • (2005) N Engl J Med , vol.353 , pp. 1591-1603
    • Robinson, B.W.1    Lake, R.A.2
  • 4
    • 65349131853 scopus 로고    scopus 로고
    • Malignant pleural mesothelioma
    • Tsao AS, Wistuba I, Roth JA et al (2009) Malignant pleural mesothelioma. J Clin Oncol 27:2081-2090
    • (2009) J Clin Oncol , vol.27 , pp. 2081-2090
    • Tsao, A.S.1    Wistuba, I.2    Roth, J.A.3
  • 5
    • 58449088744 scopus 로고    scopus 로고
    • Problems in mesothelioma diagnosis
    • Addis B, Roche H (2009) Problems in mesothelioma diagnosis. Histopathology 54:55-68
    • (2009) Histopathology , vol.54 , pp. 55-68
    • Addis, B.1    Roche, H.2
  • 7
    • 0026471095 scopus 로고
    • Extrapleural pneumonectomy in the treatment of malignant pleural mesothe-lioma
    • Sugarbaker DJ, Mentzer SJ, Strauss G (1992) Extrapleural pneumonectomy in the treatment of malignant pleural mesothe-lioma. Ann Thorac Surg 54:941-946
    • (1992) Ann Thorac Surg , vol.54 , pp. 941-946
    • Sugarbaker, D.J.1    Mentzer, S.J.2    Strauss, G.3
  • 8
    • 20244382239 scopus 로고    scopus 로고
    • The separation of benign and malignant mesothelial proliferations
    • Churg A, Colby TV, Cagle P et al (2000) The separation of benign and malignant mesothelial proliferations. Am J Surg Pathol 24:1183-1200
    • (2000) Am J Surg Pathol , vol.24 , pp. 1183-1200
    • Churg, A.1    Colby, T.V.2    Cagle, P.3
  • 9
    • 79955406661 scopus 로고    scopus 로고
    • Separation of benign and malignant mesothelial proliferations
    • Silverberg SG, Sobin LH (eds). 4th series, fascicle 3. American Registry of Pathology in collaboration with the Armed Forces Institute of Pathology, Washington
    • Churg A, Cagle PT, Roggli VL (2006) Separation of benign and malignant mesothelial proliferations. In: Silverberg SG, Sobin LH (eds) AFIP Atlas of tumor pathology: tumors of the serosal membranes. 4th series, fascicle 3. American Registry of Pathology in collaboration with the Armed Forces Institute of Pathology, Washington, pp 83-101
    • (2006) AFIP Atlas of Tumor Pathology: Tumors of the Serosal Membranes , pp. 83-101
    • Churg, A.1    Cagle, P.T.2    Roggli, V.L.3
  • 10
    • 0026785081 scopus 로고
    • Cytopathol-ogy of malignant mesothelioma: A stepwise logistic regression analysis
    • Stevens MW, Leong AS, Fazzalari NL et al (1992) Cytopathol-ogy of malignant mesothelioma: a stepwise logistic regression analysis. Diagn Cytopathol 8:333-341
    • (1992) Diagn Cytopathol , vol.8 , pp. 333-341
    • Stevens, M.W.1    Leong, A.S.2    Fazzalari, N.L.3
  • 11
    • 0034095794 scopus 로고    scopus 로고
    • The cytology of malignant mesothelioma
    • Whitaker D (2000) The cytology of malignant mesothelioma. Cytopathology 11:139-151
    • (2000) Cytopathology , vol.11 , pp. 139-151
    • Whitaker, D.1
  • 12
    • 33748773799 scopus 로고    scopus 로고
    • Cytology of the serosal surfaces
    • Silverberg SG, Sobin LH (eds). 4th series, fascicle 3. American Registry of Pathology in collaboration with the Armed Forces Institute of Pathology, Washington
    • Churg A, Cagle PT, Roggli VL (2006) Cytology of the serosal surfaces. In: Silverberg SG, Sobin LH (eds) AFIP Atlas of tumor pathology: tumors of the serosal membranes. 4th series, fascicle 3. American Registry of Pathology in collaboration with the Armed Forces Institute of Pathology, Washington, pp 11-31
    • (2006) AFIP Atlas of Tumor Pathology: Tumors of the Serosal Membranes , pp. 11-31
    • Churg, A.1    Cagle, P.T.2    Roggli, V.L.3
  • 13
    • 58149496777 scopus 로고    scopus 로고
    • Cytopathologic differential diagnosis of malignant mesothelioma, adenocarcinoma and reactive mesothelial cells: A logistic regression analysis
    • Cakir E, Demirag F, Aydin M et al (2009) Cytopathologic differential diagnosis of malignant mesothelioma, adenocarcinoma and reactive mesothelial cells: a logistic regression analysis. Diagn Cytopathol 37:4-10
    • (2009) Diagn Cytopathol , vol.37 , pp. 4-10
    • Cakir, E.1    Demirag, F.2    Aydin, M.3
  • 14
    • 72149123154 scopus 로고    scopus 로고
    • Scoring system for differential diagnosis of malignant mesothelioma and reactive mesothelial cells on cytology specimens
    • Kimura N, Data K, Araya Y et al (2009) Scoring system for differential diagnosis of malignant mesothelioma and reactive mesothelial cells on cytology specimens. Diagn Cytopathol 37:885-890
    • (2009) Diagn Cytopathol , vol.37 , pp. 885-890
    • Kimura, N.1    Data, K.2    Araya, Y.3
  • 15
    • 33947265299 scopus 로고    scopus 로고
    • Immunohistochemical detection of GLUT-1 can discriminate between reactive meso-thelium and malignant mesothelioma
    • Kato Y, Tsuta K, Seki K et al (2007) Immunohistochemical detection of GLUT-1 can discriminate between reactive meso-thelium and malignant mesothelioma. Mod Pathol 20:215-220
    • (2007) Mod Pathol , vol.20 , pp. 215-220
    • Kato, Y.1    Tsuta, K.2    Seki, K.3
  • 16
    • 78049452833 scopus 로고    scopus 로고
    • Immunocytochemistry of CD146 is useful to discriminate between malignant pleural mesothelioma and reactive mesothelium
    • Sato A, Torii I, Okamura Y et al (2010) Immunocytochemistry of CD146 is useful to discriminate between malignant pleural mesothelioma and reactive mesothelium. Mod Pathol 23: 1458-1466
    • (2010) Mod Pathol , vol.23 , pp. 1458-1466
    • Sato, A.1    Torii, I.2    Okamura, Y.3
  • 17
    • 65349097940 scopus 로고    scopus 로고
    • Usefulness of EMA, GLUT-1, and XIAP for the cytologic diagnosis of malignant mesothelioma in body cavity fluids
    • Shen J, Pinkus GS, Deshpande V et al (2009) Usefulness of EMA, GLUT-1, and XIAP for the cytologic diagnosis of malignant mesothelioma in body cavity fluids. Am J Clin Pathol 131:516-523
    • (2009) Am J Clin Pathol , vol.131 , pp. 516-523
    • Shen, J.1    Pinkus, G.S.2    Deshpande, V.3
  • 18
    • 79958003727 scopus 로고    scopus 로고
    • Oncofetal protein IMP3, a new diagnostic biomarker to distinguish malignant mesothelioma from reactive mesothelial proliferation
    • Shi M, Fraire AE, Chu P et al (2011) Oncofetal protein IMP3, a new diagnostic biomarker to distinguish malignant mesothelioma from reactive mesothelial proliferation. Am J Surg Pathol 35: 878-882
    • (2011) Am J Surg Pathol , vol.35 , pp. 878-882
    • Shi, M.1    Fraire, A.E.2    Chu, P.3
  • 19
    • 79954434468 scopus 로고    scopus 로고
    • Markers for the non-invasive diagnosis of mesothelioma: A systematic review
    • van der Bij S, Schaake E, Koffijberg H et al (2011) Markers for the non-invasive diagnosis of mesothelioma: a systematic review. Br J Cancer 104:1325-1333
    • (2011) Br J Cancer , vol.104 , pp. 1325-1333
    • Van Der Bij, S.1    Schaake, E.2    Koffijberg, H.3
  • 20
    • 27744565606 scopus 로고    scopus 로고
    • Differential diagnosis of benign and malignant mesothelial proliferations on pleural biopsies
    • Cagle PT, Churg A (2005) Differential diagnosis of benign and malignant mesothelial proliferations on pleural biopsies. Arch Pathol Lab Med 129:1421-1427
    • (2005) Arch Pathol Lab Med , vol.129 , pp. 1421-1427
    • Cagle, P.T.1    Churg, A.2
  • 21
    • 69149105448 scopus 로고    scopus 로고
    • Guidelines for pathologic diagnosis of malignant mesothelioma: A consensus statement from the International Mesothelioma Interest Group
    • Husain AN, Colby TV, Ordonez NG et al (2009) Guidelines for pathologic diagnosis of malignant mesothelioma: a consensus statement from the International Mesothelioma Interest Group. Arch Pathol Lab Med 133:1317-1331
    • (2009) Arch Pathol Lab Med , vol.133 , pp. 1317-1331
    • Husain, A.N.1    Colby, T.V.2    Ordonez, N.G.3
  • 22
    • 79955027939 scopus 로고    scopus 로고
    • Early stages of mesothelioma, screening and biomarkers
    • Klebe S, Henderson DW (2011) Early stages of mesothelioma, screening and biomarkers. Recent Results Cancer Res 189: 169-193
    • (2011) Recent Results Cancer Res , vol.189 , pp. 169-193
    • Klebe, S.1    Henderson, D.W.2
  • 23
    • 0026704232 scopus 로고
    • The concept of mesothelioma in situ: Implications for diagnosis and histogenesis
    • Whitaker D, Henderson DW, Shilkin KB (1992) The concept of mesothelioma in situ: implications for diagnosis and histogenesis. Semin Diagn Pathol 9:151-161
    • (1992) Semin Diagn Pathol , vol.9 , pp. 151-161
    • Whitaker, D.1    Henderson, D.W.2    Shilkin, K.B.3
  • 24
    • 0031755890 scopus 로고    scopus 로고
    • Reactive mes-othelial hyperplasia vs mesothelioma, including mesothelioma in situ: A brief review
    • Henderson DW, Shilkin KB, Whitaker D (1998) Reactive mes-othelial hyperplasia vs mesothelioma, including mesothelioma in situ: a brief review. Am J Clin Pathol 110:397-404
    • (1998) Am J Clin Pathol , vol.110 , pp. 397-404
    • Henderson, D.W.1    Shilkin, K.B.2    Whitaker, D.3
  • 25
    • 84892308215 scopus 로고    scopus 로고
    • Neoplasms of the pleura
    • Tomashefski JFJ (ed). chap 43. 3rd edn. Springer, New York
    • Hammar SP, Henderson DW, Klebe S et al (2008) Neoplasms of the pleura. In: Tomashefski JFJ (ed) Dail and Hammar's pulmonary pathology, chap 43, vol 2, 3rd edn. Springer, New York, pp 558-734
    • (2008) Dail and Hammar's Pulmonary Pathology , vol.2 , pp. 558-734
    • Hammar, S.P.1    Henderson, D.W.2    Klebe, S.3
  • 26
    • 0028825114 scopus 로고
    • A proposed new international TNM staging system for malignant pleural mesothelioma. from the International Mesothelioma Interest Group
    • Rusch VW (1995) A proposed new international TNM staging system for malignant pleural mesothelioma. From the International Mesothelioma Interest Group. Chest 108:1122-1128
    • (1995) Chest , vol.108 , pp. 1122-1128
    • Rusch, V.W.1
  • 27
    • 0030912190 scopus 로고    scopus 로고
    • Revisions in the international system for staging lung cancer
    • Mountain CF (1997) Revisions in the international system for staging lung cancer. Chest 111:1710-1717
    • (1997) Chest , vol.111 , pp. 1710-1717
    • Mountain, C.F.1
  • 29
    • 33748773799 scopus 로고    scopus 로고
    • Diffuse malignant tumors of the serosal membranes
    • Silverberg SG, Sobin LH (eds). 4th series, fascicle 3. American Registry of Pathology in collaboration with the Armed Forces Institute of Pathology, Washington
    • Churg A, Cagle PT, Roggli VL (2006) Diffuse malignant tumors of the serosal membranes. In: Silverberg SG, Sobin LH (eds) AFIP Atlas of tumor pathology: tumors of the serosal membranes. 4th series, fascicle 3. American Registry of Pathology in collaboration with the Armed Forces Institute of Pathology, Washington, pp 33-82
    • (2006) AFIP Atlas of Tumor Pathology: Tumors of the Serosal Membranes , pp. 33-82
    • Churg, A.1    Cagle, P.T.2    Roggli, V.L.3
  • 30
    • 0035950358 scopus 로고    scopus 로고
    • Immunocytochemistry in effusion cytology: A contemporary review
    • Fetsch PA, Abati A (2001) Immunocytochemistry in effusion cytology: a contemporary review. Cancer 93:293-308
    • (2001) Cancer , vol.93 , pp. 293-308
    • Fetsch, P.A.1    Abati, A.2
  • 31
    • 38349063254 scopus 로고    scopus 로고
    • Utility of WT-1, p63, MOC31, mesothelin, and cytokeratin (K903 and CK5/6) immu-nostains in differentiating adenocarcinoma, squamous cell carcinoma, and malignant mesothelioma in effusions
    • Pu RT, Pang Y, Michael CW (2008) Utility of WT-1, p63, MOC31, mesothelin, and cytokeratin (K903 and CK5/6) immu-nostains in differentiating adenocarcinoma, squamous cell carcinoma, and malignant mesothelioma in effusions. Diagn Cytopathol 36:20-25
    • (2008) Diagn Cytopathol , vol.36 , pp. 20-25
    • Pu, R.T.1    Pang, Y.2    Michael, C.W.3
  • 32
    • 71049175768 scopus 로고    scopus 로고
    • Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, and malignant mesothelioma
    • Bishop JA, Sharma R, Illei PB (2010) Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, and malignant mesothelioma. Hum Pathol 41:20-25
    • (2010) Hum Pathol , vol.41 , pp. 20-25
    • Bishop, J.A.1    Sharma, R.2    Illei, P.B.3
  • 33
    • 0032997034 scopus 로고    scopus 로고
    • Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesothelioma
    • Khoor A, Whitsett JA, Stahlman MT et al (1999) Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesothelioma. Hum Pathol 30:695-700
    • (1999) Hum Pathol , vol.30 , pp. 695-700
    • Khoor, A.1    Whitsett, J.A.2    Stahlman, M.T.3
  • 34
    • 0032005325 scopus 로고    scopus 로고
    • The use of epithelial membrane antigen and silver-stained nucleolar organizer regions testing in the differential diagnosis of mesothelioma from benign reactive mesothelioses
    • Wolanski KD, Whitaker D, Shilkin KB et al (1998) The use of epithelial membrane antigen and silver-stained nucleolar organizer regions testing in the differential diagnosis of mesothelioma from benign reactive mesothelioses. Cancer 82:583-590
    • (1998) Cancer , vol.82 , pp. 583-590
    • Wolanski, K.D.1    Whitaker, D.2    Shilkin, K.B.3
  • 35
    • 13844252069 scopus 로고    scopus 로고
    • The value of epithelial membrane antigen expression in separating benign mesothelial proliferation from malignant mesothelioma: A comparative study
    • Saad RS, Cho P, Liu YL (2005) The value of epithelial membrane antigen expression in separating benign mesothelial proliferation from malignant mesothelioma: a comparative study. Diagn Cytopathol 32:156-159
    • (2005) Diagn Cytopathol , vol.32 , pp. 156-159
    • Saad, R.S.1    Cho, P.2    Liu, Y.L.3
  • 36
    • 0141613691 scopus 로고    scopus 로고
    • The use of immuno-histochemistry in distinguishing reactive from neoplastic meso-thelium. A novel use for desmin and comparative evaluation with epithelial membrane antigen, p53, platelet-derived growth factor-receptor, P-glycoprotein and Bcl-2
    • Attanoos RL, Griffin A, Gibbs AR (2003) The use of immuno-histochemistry in distinguishing reactive from neoplastic meso-thelium. A novel use for desmin and comparative evaluation with epithelial membrane antigen, p53, platelet-derived growth factor-receptor, P-glycoprotein and Bcl-2. Histopathology 43:231-238
    • (2003) Histopathology , vol.43 , pp. 231-238
    • Attanoos, R.L.1    Griffin, A.2    Gibbs, A.R.3
  • 37
    • 0027102650 scopus 로고
    • Immunore-activity for p53 protein in malignant mesothelioma and non-neoplastic mesothelium
    • Ramael M, Lemmens G, Eerdekens C et al (1992) Immunore-activity for p53 protein in malignant mesothelioma and non-neoplastic mesothelium. J Pathol 168:371-375
    • (1992) J Pathol , vol.168 , pp. 371-375
    • Ramael, M.1    Lemmens, G.2    Eerdekens, C.3
  • 38
    • 0027992278 scopus 로고
    • Desmin and neural marker expression in mesothelial cells and mesotheliomas
    • Hurlimann J (1994) Desmin and neural marker expression in mesothelial cells and mesotheliomas. Hum Pathol 25:753-757
    • (1994) Hum Pathol , vol.25 , pp. 753-757
    • Hurlimann, J.1
  • 39
    • 0034760195 scopus 로고    scopus 로고
    • The role of desmin and N-cadherin in effusion cytology: A comparative study using established markers of mesothelial and epithelial cells
    • Davidson B, Nielsen S, Christensen J et al (2001) The role of desmin and N-cadherin in effusion cytology: a comparative study using established markers of mesothelial and epithelial cells. Am J Surg Pathol 25:1405-1412
    • (2001) Am J Surg Pathol , vol.25 , pp. 1405-1412
    • Davidson, B.1    Nielsen, S.2    Christensen, J.3
  • 40
    • 0032833853 scopus 로고    scopus 로고
    • The use of histo-logical and immunohistochemical markers to distinguish pleural malignant mesothelioma and in situ mesothelioma from reactive mesothelial hyperplasia and reactive pleural fibrosis
    • Cury PM, Butcher DN, Corrin B et al (1999) The use of histo-logical and immunohistochemical markers to distinguish pleural malignant mesothelioma and in situ mesothelioma from reactive mesothelial hyperplasia and reactive pleural fibrosis. J Pathol 189:251-257
    • (1999) J Pathol , vol.189 , pp. 251-257
    • Cury, P.M.1    Butcher, D.N.2    Corrin, B.3
  • 41
    • 33845524422 scopus 로고    scopus 로고
    • Sensitivity and specificity of immunohistochemical antibodies used to distinguish between benign and malignant pleural disease: A systematic review of published reports
    • King J, Thatcher N, Pickering C et al (2006) Sensitivity and specificity of immunohistochemical antibodies used to distinguish between benign and malignant pleural disease: a systematic review of published reports. Histopathology 49:561-568
    • (2006) Histopathology , vol.49 , pp. 561-568
    • King, J.1    Thatcher, N.2    Pickering, C.3
  • 42
    • 0036187373 scopus 로고    scopus 로고
    • Expression of telo-merase reverse transcriptase (TERT) in malignant mesothelio-mas
    • Kumaki F, Kawai T, Churg A et al (2002) Expression of telo-merase reverse transcriptase (TERT) in malignant mesothelio-mas. Am J Surg Pathol 26:365-370
    • (2002) Am J Surg Pathol , vol.26 , pp. 365-370
    • Kumaki, F.1    Kawai, T.2    Churg, A.3
  • 43
    • 0029155471 scopus 로고
    • Codeletion of p15 and p16 in primary malignant mesothelioma
    • Xio S, Li D, Vijg J et al (1995) Codeletion of p15 and p16 in primary malignant mesothelioma. Oncogene 11:511-515
    • (1995) Oncogene , vol.11 , pp. 511-515
    • Xio, S.1    Li, D.2    Vijg, J.3
  • 44
    • 0032498502 scopus 로고    scopus 로고
    • The gene for the cyclin-dependent-kinase-4 inhibitor, CDKN2A, is preferentially deleted in malignant mesothelioma
    • Prins JB, Williamson KA, Kamp MM et al (1998) The gene for the cyclin-dependent-kinase-4 inhibitor, CDKN2A, is preferentially deleted in malignant mesothelioma. Int J Cancer 75:649-653
    • (1998) Int J Cancer , vol.75 , pp. 649-653
    • Prins, J.B.1    Williamson, K.A.2    Kamp, M.M.3
  • 45
    • 47049096400 scopus 로고    scopus 로고
    • 9p21 Deletion in the diagnosis of malignant mesothelioma in serous effusions additional to immunocytochemistry, DNA-ICM, and AgNOR analysis
    • Onofre FB, Onofre AS, Pomjanski N et al (2008) 9p21 Deletion in the diagnosis of malignant mesothelioma in serous effusions additional to immunocytochemistry, DNA-ICM, and AgNOR analysis. Cancer 114:204-215
    • (2008) Cancer , vol.114 , pp. 204-215
    • Onofre, F.B.1    Onofre, A.S.2    Pomjanski, N.3
  • 46
    • 77951919594 scopus 로고    scopus 로고
    • 9p21 deletion in the diagnosis of malignant mesothelioma, using fluorescence in situ hybridization analysis
    • Takeda M, Kasai T, Enomoto Y et al (2010) 9p21 deletion in the diagnosis of malignant mesothelioma, using fluorescence in situ hybridization analysis. Pathol Int 60:395-399
    • (2010) Pathol Int , vol.60 , pp. 395-399
    • Takeda, M.1    Kasai, T.2    Enomoto, Y.3
  • 47
    • 77955765208 scopus 로고    scopus 로고
    • FISH assay development for the detection of p16/CDKN2A deletion in malignant pleural mesothelioma
    • Chung CT, Santos Gda C, Hwang DM et al (2010) FISH assay development for the detection of p16/CDKN2A deletion in malignant pleural mesothelioma. J Clin Pathol 63:630-634
    • (2010) J Clin Pathol , vol.63 , pp. 630-634
    • Chung, C.T.1    Santos Gda, C.2    Hwang, D.M.3
  • 48
    • 79954600100 scopus 로고    scopus 로고
    • The diagnostic utility of p16 FISH and GLUT-1 immunohistochemical analysis in mesothelial proliferations
    • Monaco SE, Shuai Y, Bansal M et al (2011) The diagnostic utility of p16 FISH and GLUT-1 immunohistochemical analysis in mesothelial proliferations. Am J Clin Pathol 135:619-627
    • (2011) Am J Clin Pathol , vol.135 , pp. 619-627
    • Monaco, S.E.1    Shuai, Y.2    Bansal, M.3
  • 49
    • 79955442548 scopus 로고    scopus 로고
    • Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumori-genesis
    • Altomare DA, Menges CW, Xu J et al (2011) Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumori-genesis. PloS One 6:e18828
    • (2011) PloS One , vol.6
    • Altomare, D.A.1    Menges, C.W.2    Xu, J.3
  • 50
    • 0028907620 scopus 로고
    • Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer
    • Sekido Y, Pass HI, Bader S et al (1995) Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer. Cancer Res 55:1227-1231
    • (1995) Cancer Res , vol.55 , pp. 1227-1231
    • Sekido, Y.1    Pass, H.I.2    Bader, S.3
  • 51
    • 0028818921 scopus 로고
    • High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas
    • Bianchi AB, Mitsunaga SI, Cheng JQ et al (1995) High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas. Proc Natl Acad Sci USA 92:10854-10858
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10854-10858
    • Bianchi, A.B.1    Mitsunaga, S.I.2    Cheng, J.Q.3
  • 52
    • 33645757835 scopus 로고    scopus 로고
    • The distribution of constitutional and somatic mutations in the neurofibromatosis 2 gene
    • Baser ME (2006) The distribution of constitutional and somatic mutations in the neurofibromatosis 2 gene. Hum Mutat 27:297-306
    • (2006) Hum Mutat , vol.27 , pp. 297-306
    • Baser, M.E.1
  • 53
    • 25844447107 scopus 로고    scopus 로고
    • Membrane organization and tumorigenesis-the NF2 tumor suppressor, Merlin
    • McClatchey AI, Giovannini M (2005) Membrane organization and tumorigenesis-the NF2 tumor suppressor, Merlin. Genes Dev 19:2265-2277
    • (2005) Genes Dev , vol.19 , pp. 2265-2277
    • McClatchey, A.I.1    Giovannini, M.2
  • 54
    • 79551570342 scopus 로고    scopus 로고
    • LATS2 is a tumor suppressor gene of malignant mesothelioma
    • Murakami H, Mizuno T, Taniguchi T et al (2011) LATS2 is a tumor suppressor gene of malignant mesothelioma. Cancer Res 71:873-883
    • (2011) Cancer Res , vol.71 , pp. 873-883
    • Murakami, H.1    Mizuno, T.2    Taniguchi, T.3
  • 55
    • 24944522720 scopus 로고    scopus 로고
    • A mouse model recapitulating molecular features of human mesothelioma
    • Altomare DA, Vaslet CA, Skele KL et al (2005) A mouse model recapitulating molecular features of human mesothelioma. Cancer Res 65:8090-8095
    • (2005) Cancer Res , vol.65 , pp. 8090-8095
    • Altomare, D.A.1    Vaslet, C.A.2    Skele, K.L.3
  • 56
    • 15144342687 scopus 로고    scopus 로고
    • BAP1: A novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression
    • Jensen DE, Proctor M, Marquis ST et al (1998) BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. Oncogene 16:1097-1112
    • (1998) Oncogene , vol.16 , pp. 1097-1112
    • Jensen, D.E.1    Proctor, M.2    Marquis, S.T.3
  • 57
    • 58249095937 scopus 로고    scopus 로고
    • BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity
    • Nishikawa H, Wu W, Koike A et al (2009) BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity. Cancer Res 69:111-119
    • (2009) Cancer Res , vol.69 , pp. 111-119
    • Nishikawa, H.1    Wu, W.2    Koike, A.3
  • 58
    • 78649700287 scopus 로고    scopus 로고
    • Frequent mutation of BAP1 in metastasizing uveal melanomas
    • Harbour JW, Onken MD, Roberson ED et al (2010) Frequent mutation of BAP1 in metastasizing uveal melanomas. Science 330:1410-1413
    • (2010) Science , vol.330 , pp. 1410-1413
    • Harbour, J.W.1    Onken, M.D.2    Roberson, E.D.3
  • 59
    • 79959694149 scopus 로고    scopus 로고
    • The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma
    • Bott M, Brevet M, Taylor BS et al (2011) The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma. Nat Genet 43:668-672
    • (2011) Nat Genet , vol.43 , pp. 668-672
    • Bott, M.1    Brevet, M.2    Taylor, B.S.3
  • 60
    • 80053385701 scopus 로고    scopus 로고
    • Germline BAP1 mutations predispose to malignant mesothelioma
    • Testa JR, Cheung M, Pei J et al (2011) Germline BAP1 mutations predispose to malignant mesothelioma. Nat Genet 43:1022-1025
    • (2011) Nat Genet , vol.43 , pp. 1022-1025
    • Testa, J.R.1    Cheung, M.2    Pei, J.3
  • 61
    • 80054808016 scopus 로고    scopus 로고
    • Frequent deletion of 3p21.1 region carrying semaphorin 3G and aberrant expression of the genes participating in semaphorin signaling in the epithe-lioid type of malignant mesothelioma cells
    • Yoshikawa Y, Sato A, Tsujimura T et al (2011) Frequent deletion of 3p21.1 region carrying semaphorin 3G and aberrant expression of the genes participating in semaphorin signaling in the epithe-lioid type of malignant mesothelioma cells. Int J Oncol 39:1365-1374
    • (2011) Int J Oncol , vol.39 , pp. 1365-1374
    • Yoshikawa, Y.1    Sato, A.2    Tsujimura, T.3
  • 62
    • 33846674993 scopus 로고    scopus 로고
    • Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non random chromosomal alteration regions including JUN amplification on 1p32
    • Taniguchi T, Karnan S, Fukui T et al (2007) Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32. Cancer Sci 98:438-446
    • (2007) Cancer Sci , vol.98 , pp. 438-446
    • Taniguchi, T.1    Karnan, S.2    Fukui, T.3
  • 63
    • 31344449869 scopus 로고    scopus 로고
    • EGFR overex-pression in malignant pleural mesothelioma. An immunohisto-chemical and molecular study with clinico-pathological correlations
    • Destro A, Ceresoli GL, Falleni M et al (2006) EGFR overex-pression in malignant pleural mesothelioma. An immunohisto-chemical and molecular study with clinico-pathological correlations. Lung Cancer 51:207-215
    • (2006) Lung Cancer , vol.51 , pp. 207-215
    • Destro, A.1    Ceresoli, G.L.2    Falleni, M.3
  • 64
    • 24944539840 scopus 로고    scopus 로고
    • Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth
    • Altomare DA, You H, Xiao GH et al (2005) Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth. Onco-gene 24:6080-6089
    • (2005) Onco-gene , vol.24 , pp. 6080-6089
    • Altomare, D.A.1    You, H.2    Xiao, G.H.3
  • 65
    • 67650099861 scopus 로고    scopus 로고
    • Activation of the PI3K-AKT pathway in human malignant mesothelioma cells
    • Suzuki Y, Murakami H, Kawaguchi K et al (2009) Activation of the PI3K-AKT pathway in human malignant mesothelioma cells. Mol Med Rep 2:181-188
    • (2009) Mol Med Rep , vol.2 , pp. 181-188
    • Suzuki, Y.1    Murakami, H.2    Kawaguchi, K.3
  • 66
    • 0035511772 scopus 로고    scopus 로고
    • Mutational analysis of the PTEN/MMAC1 tumour suppressor gene in primary human malignant mesotheliomas
    • Papp T, Schipper H, Pemsel H et al (2001) Mutational analysis of the PTEN/MMAC1 tumour suppressor gene in primary human malignant mesotheliomas. Oncol Rep 8:1375-1379
    • (2001) Oncol Rep , vol.8 , pp. 1375-1379
    • Papp, T.1    Schipper, H.2    Pemsel, H.3
  • 68
    • 0035258783 scopus 로고    scopus 로고
    • ARF and CDK4 genes in primary human malignant mesotheliomas
    • ARF and CDK4 genes in primary human malignant mesotheliomas. Int J Oncol 18:425-433
    • (2001) Int J Oncol , vol.18 , pp. 425-433
    • Papp, T.1    Schipper, H.2    Pemsel, H.3
  • 69
    • 33847293670 scopus 로고    scopus 로고
    • High-throughput oncogene mutation profiling in human cancer
    • Thomas RK, Baker AC, Debiasi RM et al (2007) High-throughput oncogene mutation profiling in human cancer. Nat Genet 39:347-351
    • (2007) Nat Genet , vol.39 , pp. 347-351
    • Thomas, R.K.1    Baker, A.C.2    Debiasi, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.