The newly synthesized anticancer drug HUHS1015 is useful for treatment of human gastric cancer

Cancer Chemotherapy and Pharmacology

Volumn 75, Issue 3, 2015, Pages 527-535

  Kaku, Yoshiko ^a   Tsuchiya, Ayako ^a   Kanno, Takeshi ^a   Nakao, Shuhei ^a   Shimizu, Tadashi ^a   Tanaka, Akito ^a   Nishizaki, Tomoyuki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Anticancer drug; Apoptosis; Gastric cancer; HUHS1015; Suppression of tumor growth

Indexed keywords

1 [2 (2 METHOXYPHENYLAMINO)ETHYLAMINO] 3 (NAPHTHALENE 1 YLOXY)PROPAN 2 OL; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 4; CASPASE 8; CISPLATIN; EFFECTOR CASPASE; IRINOTECAN; MESSENGER RNA; PACLITAXEL; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; 1-(2-(2-METHOXYPHENYLAMINO)ETHYLAMINO)-3-(NAPHTHALENE-1-YLOXY)PROPAN-2-OL; ANILINE DERIVATIVE; CASPASE; PROPANOLAMINE DERIVATIVE; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; FLOW CYTOMETRY; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH ADENOCARCINOMA; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR NECROSIS; UPREGULATION; ADENOCARCINOMA; ANIMAL; BAGG ALBINO MOUSE; CELL PROLIFERATION; CELL SURVIVAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM; NUDE MOUSE; PATHOLOGY; STOMACH NEOPLASMS; TUMOR CELL LINE;

ADENOCARCINOMA; ANILINE COMPOUNDS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; PROPANOLAMINES; RNA, MESSENGER; STOMACH NEOPLASMS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84925503429     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-014-2661-z     Document Type: Article

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