Chronic cat allergen exposure induces a TH2 cell-dependent IgG4 response related to low sensitization

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 6, 2015, Pages 1627-1635.e13

  Renand, Amedee ^a   Archila, Luis D ^a   McGinty, John ^a   Wambre, Erik ^a   Robinson, David ^b   Hales, Belinda J ^d   Thomas, Wayne R ^d   Kwok, William W ^a,c  

^a BENAROYA RESEARCH INSTITUTE   (United States)

^b VIRGINIA MASON MEDICAL CENTER   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

allergen exposure; allergen tolerance; asthma; Cat allergy; CD154; class II tetramer; Fel d 1; Fel d 4; IgG4; TH2 cells

Indexed keywords

ALLERGEN; CD40 LIGAND; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G4; PROTEIN FEL D 1; PROTEIN FEL D 4; PROTEIN FEL D 7; PROTEIN FEL D 8; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; IMMUNOGLOBULIN G;

ALLERGY; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; ASTHMA; B LYMPHOCYTE; CAT; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DESENSITIZATION; EX VIVO STUDY; HUMAN; HUMAN CELL; PRICK TEST; PRIORITY JOURNAL; RHINITIS; T LYMPHOCYTE; TH2 CELL; ADULT; AGED; ANIMAL; BLOOD; HYPERSENSITIVITY; IMMUNOLOGY; MIDDLE AGED; SKIN TEST;

ADULT; AGED; ALLERGENS; ANIMALS; B-LYMPHOCYTES; CATS; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; MIDDLE AGED; SKIN TESTS; T-LYMPHOCYTES;

EID: 84952638825     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.07.031     Document Type: Article

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