Specific immunotherapy modifies allergen-specific CD4+ T-cell responses in an epitope-dependent manner

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 3, 2014, Pages

  Wambre, Erik ^a   Delong, Jonathan H ^a   James, Eddie A ^a   Torres Chinn, Nadia ^a   Pfützner, Wolfgang ^b   Möbs, Christian ^b   Durham, Stephen R ^c   Till, Stephen J ^d   Robinson, David ^e,f   Kwok, William W ^a  

^a BENAROYA RESEARCH INSTITUTE   (United States)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e VIRGINIA MASON MEDICAL CENTER   (United States)

^f UNIVERSITY OF WASHINGTON   (United States)

Author keywords

allergy; CD4; epitope; ex vivo; Immunotherapy; peptide MHC class II tetramer; peripheral tolerance; pollen; T cells

Indexed keywords

ALLERGEN; EPITOPE; FORKHEAD TRANSCRIPTION FACTOR; GAMMA INTERFERON; GRASS POLLEN VACCINE; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 4; PEPTIDE;

ALLELE; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; GRASS POLLEN; HLA SYSTEM; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; IMMUNOSTIMULATION; IMMUNOTHERAPY; NONHUMAN; PHENOTYPE; PHLEUM PRATENSE; POLLEN ALLERGY; PRICK TEST; PRIORITY JOURNAL; SKIN TEST;

ALLERGY; CD4; EPITOPE; EX VIVO; IMMUNOTHERAPY; PEPTIDE-MHC CLASS II TETRAMER; PERIPHERAL TOLERANCE; POLLEN; T CELLS;

ALLERGENS; ANTIGENS, CD27; CD4-POSITIVE T-LYMPHOCYTES; DESENSITIZATION, IMMUNOLOGIC; EPITOPES, T-LYMPHOCYTE; HUMANS; IMMUNE TOLERANCE; IMMUNOPHENOTYPING; PHLEUM; TH1 CELLS; TH2 CELLS;

EID: 84896729297     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.10.054     Document Type: Article

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