Disruption of Physiological Balance between Nitric Oxide and Endothelium-Dependent Hyperpolarization Impairs Cardiovascular Homeostasis in Mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 1, 2016, Pages 97-107

  Godo, Shigeo ^a   Sawada, Ayuko ^a   Saito, Hiroki ^a   Ikeda, Shohei ^a   Enkhjargal, Budbazar ^a   Suzuki, Kota ^a   Tanaka, Shuhei ^a   Shimokawa, Hiroaki ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

caveolin 1; endothelium; endothelium dependent hyperpolarization factor; nitric oxide

Indexed keywords

CAVEOLIN 1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROGEN PEROXIDE; NITRATE; NITRIC OXIDE; NITRITE; UNCLASSIFIED DRUG; BIOLOGICAL FACTOR; CAV1 PROTEIN, MOUSE; ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION FACTOR; ENZYME INHIBITOR; NOS3 PROTEIN, MOUSE; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; ARTICLE; CARDIOVASCULAR HOMEOSTASIS; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; CORONARY FLOW RESERVE; ENDOTHELIUM DEPENDENT HYPERPOLARIZATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENOTYPE; HEART VENTRICLE HYPERTROPHY; HYPERPOLARIZATION; HYPOTENSION; IN VIVO STUDY; LEFT VENTRICULAR SYSTOLIC DYSFUNCTION; MESENTERIC ARTERY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; VASODILATATION; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CARDIAC MUSCLE; CARDIOMEGALY; CELL HYPOXIA; COMPARATIVE STUDY; CORONARY ARTERY BLOOD FLOW; DEFICIENCY; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HEART LEFT VENTRICLE FUNCTION; HOMEOSTASIS; ISOLATED HEART; KNOCKOUT MOUSE; MALE; MEMBRANE POTENTIAL; METABOLISM; MICROCIRCULATION; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SYSTOLE; TIME FACTOR; UPREGULATION; VASCULAR ENDOTHELIUM;

ANIMALS; BIOLOGICAL FACTORS; CARDIOMEGALY; CAVEOLIN 1; CELL HYPOXIA; CORONARY CIRCULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENOTYPE; HOMEOSTASIS; HYPOTENSION; ISOLATED HEART PREPARATION; MALE; MEMBRANE POTENTIALS; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROCIRCULATION; MYOCARDIUM; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHENOTYPE; SIGNAL TRANSDUCTION; SYSTOLE; TIME FACTORS; UP-REGULATION; VASODILATION; VASODILATOR AGENTS; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

EID: 84952637950     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.306499     Document Type: Article

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