Reduced hyperpolarization in endothelial cells of rabbit aortic valve following chronic nitroglycerine administration

British Journal of Pharmacology

Volumn 146, Issue 4, 2005, Pages 487-497

  Kusama, Nobuyoshi ^a   Kajikuri, Junko ^a   Yamamoto, Tamao ^a   Watanabe, Yoshimasa ^a   Suzuki, Yoshikatsu ^a   Katsuya, Hirotada ^a   Itoh, Takeo ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Aortic valve; Endothelial cell; Endothelium dependent hyperpolarization; Nitrate tolerance; Superoxide

Indexed keywords

1 ETHYL 2 BENZIMIDAZOLINONE; ACETYLCHOLINE; ACETYLCYSTEINE; ANTIOXIDANT; APAMIN; ASCORBIC ACID; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHARYBDOTOXIN; EBSELEN; ETHIDIUM; GLYCERYL TRINITRATE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN; PORPHYRIN DERIVATIVE; SCAVENGER; SUPEROXIDE; TIRON; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA VALVE; ARTICLE; CALCIUM CONDUCTANCE; CELL LINE; CONTROLLED STUDY; DOWN REGULATION; DRUG TOLERANCE; ENDOTHELIUM CELL; HYPERPOLARIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ACETYLCHOLINE; ANIMALS; ANTIOXIDANTS; AORTIC VALVE; APAMIN; ASCORBIC ACID; BENZIMIDAZOLES; BIOLOGICAL FACTORS; CALCIUM; CALCIUM CHANNEL AGONISTS; CHARYBDOTOXIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG TOLERANCE; ENDOTHELIAL CELLS; IONOMYCIN; IONOPHORES; MALE; MEMBRANE POTENTIALS; NITROGLYCERIN; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RABBITS; SUPEROXIDES; TIME FACTORS; VASODILATOR AGENTS;

EID: 27144432409     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706363     Document Type: Article

References (62)

1. BÉNY, J. (1997). Electrical coupling between smooth muscle cells and endothelial cells in pig coronary arteries. Pflügers Arch., 433, 364-367.
2. BÉNY, J. & PACICCA, C. (1994). Bidirectional electrical communication between smooth muscle and endothelial cells in the pig coronary artery. Am. J. Physiol., 266, H1465-H1472.
3. BERKENBOOM, G., FONTAINE, D., UNGER, P., BALDASSARRE, S., PREUMONT, N. & FONTAINE, J. (1999). Absence of nitrate tolerance after long-term treatment with ramipril: an endothelium-dependent mechanism. J. Cardiovasc. Pharmacol., 34, 547-553.
4. + channel in renal artery endothelium in situ by nitric oxide and reactive oxygen species. Kidney Int., 64, 199-207.
5. BRUNET, P. & BÉNY, J. (1989). Substance P and bradykinin hyperpolarize pig coronary artery endothelial cells in primary culture. Blood Vessels, 26, 228-234.
6. + channels in rat cerebral artery smooth muscle cells. Am. J. Physiol., 278, H1883-H1890.
7. BUSSE, R., EDWARDS, G., FELETOU, M., FLEMING, I., VANHOUTTE, P. & WESTON, A. (2002). EDHF: bringing the concepts together. Trends Pharmacol. Sci., 23, 374-380.
8. + channel in porcine coronary endothelium: relevance to EDHF. Br. J. Pharmacol., 137, 1346-1354.
9. BYCHKOV, R., PIEPER, K., RIED, C., MILOSHEVA, M., BYCHKOV, E., LUFT, F. & HALLER, H. (1999). Hydrogen peroxide, potassium currents, and membrane potential in human endothelial cells. Circulation, 99, 1719-1725.
10. CAI, H. & HARRISON, D. (2000). Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res., 87, 840-844.
11. 2+) channel of intermediate conductance in bovine aortic endothelial cells. J. Membr. Biol., 158, 147-158.
12. CARAMORI, P., ADELMAN, A., AZEVEDO, E., NEWTON, G., PARKER, A. & PARKER, J. (1998). Therapy with nitroglycerin increases coronary vasoconstriction in response to acetylcholine. J. Am. Coll. Cardiol., 32, 1969-1974.
13. 2+ concentration recorded in endothelial cells in situ in the isolated rat aorta. Pflügers Arch., 428, 476-484.
14. CHEN, G. & CHEUNG, D. (1992). Characterization of acetylcholine-induced membrane hyperpolarization in endothelial cells. Circ. Res., 70, 257-263.
15. DAIBER, A., ZOU, M., BACHSCHMID, M. & ULLRICH, V. (2000). Ebselen as a peroxynitrite scavenger in vitro and ex vivo. Biochem. Pharmacol., 59, 153-160.
16. EDWARDS, G., GARDENER, M., FELETOU, M., BRADY, G., VANHOUTTE, P. & WESTON, A. (1999). Further investigation of endothelium-derived hyperpolarizing factor (EDHF) in rat hepatic artery: studies using 1-EBIO and ouabain. Br. J. Pharmacol., 128, 1064-1070.
17. +-channels suppresses EDHF-mediated vasodilation. Br. J. Pharmacol., 138, 594-601.
18. FRIEDEN, M. & BÉNY, J. (1995). Effect of 5-hydroxytryptamine on the membrane potential of endothelial and smooth muscle cells in the pig coronary artery. Br. J. Pharmacol., 115, 95-100.
19. GAUTHIER, K., DEETER, C., KRISHNA, U., REDDY, Y., BONDLELA, M., FALCK, J. & CAMPBELL, W. (2002). 14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries. Circ. Res., 90, 1028-1036.
20. GORI, T., MAK, S., KELLY, S. & PARKER, J. (2001). Evidence supporting abnormalities in nitric oxide synthase function induced by nitroglycerin in humans. J. Am. Coll. Cardiol., 38, 1096-1101.
21. GORI, T. & PARKER, J. (2002a). Nitrate tolerance: a unifying hypothesis. Circulation, 106, 2510-2513.
22. GORI, T. & PARKER, J. (2002b). The puzzle of nitrate tolerance: pieces smaller than we thought? Circulation, 106, 2404-2408.
23. GRIFFITH, T.M. (2004). Endothelium-dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis? Br. J. Pharmacol., 141, 881-903.
24. GRIFFITH, T.M., CHAYTOR, A.T. & EDWARDS, D.H. (2004). The obligatory link: role of gap junctional communication in endothelium-dependent smooth muscle hyperpolarization. Pharmacol. Res., 49, 551-564.
25. GRIFFITH, T.M., CHAYTOR, A.T., TAYLOR, H.J., GIDDINGS, B.D. & EDWARDS, D.H. (2002). cAMP facilitates EDHF-type relaxations in conduit arteries by enhancing electronic conduction via gap junctions. Proc. Natl. Acad. Sci. U.S.A. 99, 6392-6397.
26. HASHIMOTO, S., GON, Y., MATSUMOTO, K., TAKESHITA, I. & HORIE, T. (2001). N-acetylcysteine attenuates TNF-alpha-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells. Br. J. Pharmacol., 132, 270-276.
27. i and membrane currents in single bovine aortic endothelial cells. Am. J. Physiol., 267, C1338-C1350.
28. HINK, U., OELZE, M., KOLB, P., BACHSCHMID, M., ZOU, M., DAIBER, A., MOLLNAU, H., AUGUST, M., BALDUS, S., TSILIMINGAS, N., WALTER, U., ULLRICH, V. & MÜNZEL, T. (2003). Role for peroxynitrite in the inhibition of prostacyclin synthase in nitrate tolerance. J. Am. Coll. Cardiol., 42, 1826-1834.
29. +-channel inhibitors in rat isolated mesenteric arteries. Br. J. Pharmacol., 138, 1031-1035.
30. INDIK, J., GOLDMAN, S. & GABALLA, M. (2001). Oxidative stress contributes to vascular endothelial dysfunction in heart failure. Am. J. Physiol., 281, H1767-H1770.
31. KLEIN, J. & O'NEILL, W. (1990). Effect of bradykinin on Na-K-2Cl cotransport and bumetanide binding in aortic endothelial cells. J. Biol. Chem., 265, 22238-22242.
32. KRETTEK, A., SUKHOVA, G., SCHONBECK, U. & LIBBY, P. (2004). Enhanced expression of CD44 variants in human atheroma and abdominal aortic aneurysm: possible role for a feedback loop in endothelial cells. Am. J. Pathol., 165, 1571-1581.
33. KURIYAMA, H., KITAMURA, K., ITOH, T. & INOUE, R. (1998). Physiological features of visceral smooth muscle cells, with special reference to receptors and ion channels. Physiol. Rev., 78, 811-920.
34. KUSAMA, N., KAJIKURI, J., WATANABE, Y., SUZUKI, Y., KATSUYA, H. & ITOH, T. (2005). Characteristics of attenuated endothelium-dependent relaxation seen in rabbit intrapulmonary vein following chronic nitroglycerine administration. Br. J. Pharmacol., 145, 193-202.
35. LAURSEN, J., BOESGAARD, S., POULSEN, H. & ALDERSHVILE, J. (1996). Nitrate tolerance impairs nitric oxide-mediated vasodilation in vivo. Cardiovasc. Res., 31, 814-819.
36. + channel activity in smooth muscle of human coronary arterioles. Circ. Res., 91, 1070-1076.
37. LÜCKHOFF, A. & BUSSE, R. (1990). Activators of potassium channels enhance calcium influx into endothelial cells as a consequence of potassium currents. Naunyn Schmiedeberg's Arch. Pharmacol., 342, 94-99.
38. MARCHENKO, S. & SAGE, S. (1993). Electrical properties of resting and acetylcholine-stimulated endothelium in intact rat aorta. J. Physiol., 462, 735-751.
39. MARCHENKO, S. & SAGE, S. (1994). Smooth muscle cells affect endothelial membrane potential in rat aorta. Am. J. Physiol., 267, H804-H811.
40. MARCHENKO, S. & SAGE, S. (1996). Calcium-activated potassium channels in the endothelium of intact rat aorta. J. Physiol., 492, 53-60.
41. MARKLUND, S. & MARKLUND, G. (1974). Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem., 47, 469-474.
42. Ca channels in cerebral EDHF-mediated dilations. Am. J. Physiol., 285, H1590-H1599.
43. MAYS, B.W., FREISCHLAG, J.A., EGINTON, M.T., CAMBRIA, R.A., SEABROOK, G.R. & TOWNE, J.B. (1999). Ascorbic acid prevents cigarette smoke injury to endothelium-dependent arterial relaxation. J. Surg. Res., 84, 35-39.
44. MEHRKE, G. & DAUT, J. (1990). The electrical response of cultured guinea-pig coronary endothelial cells to endothelium-dependent vasodilators. J. Physiol., 430, 251-272.
45. MÜNZEL, T., LI, H., MOLLNAU, H., HINK, U., MATHEIS, E., HARTMANN, M., OELZE, M., SKATCHKOV, M., WARNHOLTZ, A., DUNCKER, L., MEINERTZ, T. & FORSTERMANN, U. (2000). Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability. Circ. Res., 86, E7-E12.
46. MÜNZEL, T., SAYEGH, H., FREEMAN, B., TARPEY, M. & HARRISON, D. (1995). Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. J. Clin. Invest., 95, 187-194.
47. NAKANO, Y., KUSAMA, N., KAJIKURI, J., SUZUKI, Y., KANMURA, Y. & ITOH, T. (2004). Role of PKC in the attenuation of the cGMP-mediated relaxation of skinned resistance artery smooth muscle seen in glyceryl-trinitrate-tolerant rabbit. Br. J. Pharmacol., 141, 391-398.
48. NILIUS, B., VIANA, F. & DROOGMANS, G. (1997). Ion channels in vascular endothelium. Annu. Rev. Physiol., 59, 145-170.
49. OHASHI, M., SATOH, K. & ITOH, T. (1999). Acetylcholine-induced membrane potential changes in endothelial cells of rabbit aortic valve. Br. J. Pharmacol., 126, 19-26.
50. PARKER, J., FARRELL, B., FENTON, T., COHANIM, M. & PARKER, J. (1991). Counter-regulatory responses to continuous and intermittent therapy with nitroglycerin. Circulation, 84, 2336-2345.
51. PARUMS, D.V., CORDELL, J.L., MICKLEM, K., HERYET, A.R., GATTER, K.C. & MASON, D.Y. (1990). JC70: a new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections. J. Clin. Pathol., 43, 752-757.
52. PERRY, P. & O'NEILL, W. (1993). Swelling-activated K fluxes in vascular endothelial cells: volume regulation via K-Cl cotransport and K channels. Am. J. Physiol., 265, C763-C769.
53. QUIJANO, C., HERNANDEZ-SAAVEDRA, D., CASTRO, L., MCCORD, J., FREEMAN, B. & RADI, R. (2001). Reaction of peroxynitrite with Mn-superoxide dismutase. Role of the metal center in decomposition kinetics and nitration. J. Biol. Chem., 276, 11631-11638.
54. Ca channel cerebrovasodilation. Am. J. Physiol., 285, R149-R154.
55. SAKAI, T. (1990). Acetylcholine induces Ca-dependent K currents in rabbit endothelial cells. Jpn. J. Pharmacol., 53, 235-246.
56. SAWA, T., AKAIKE, T. & MAEDA, H. (2000). Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase. J. Biol. Chem., 275, 32467-32474.
57. SCHWENKE, D.C. & BEHR, S.R. (1998). Vitamin E combined with selenium inhibits atherosclerosis in hypercholesterolemic rabbits independently of effects on plasma cholesterol concentrations. Circ Res., 83, 366-377.
58. SHARMA, N. & DAVIS, M. (1994). Mechanism of substance P-induced hyperpolarization of porcine coronary artery endothelial cells. Am. J. Physiol., 266, H156-H164.
59. SONG, J. & DAVIS, M. (1994). Chloride and cation currents activated by bradykinin in coronary venular endothelial cells. Am. J. Physiol., 267, H2508-H2515.
60. VON DER WEID, P.Y. & BÉNY, J. (1993). Simultaneous oscillations in the membrane potential of pig coronary artery endothelial and smooth muscle cells. J. Physiol., 471, 13-24.
61. WANG, X., CHU, W. & VAN, B.C. (1996). Potentiation of acetylcholine-induced responses in freshly isolated rabbit aortic endothelial cells. J. Vasc. Res., 33, 414-424.
62. ZHANG, H., SPAPEN, H., NGUYEN, D., BENLABED, M., BUURMAN, W. & VINCENT, J. (1994). Protective effects of N-acetyl-L-cysteine in endotoxemia. Am. J. Physiol., 266, H1746-H1754.