APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

Alzheimer's and Dementia

Volumn 11, Issue 12, 2015, Pages 1417-1429

  Risacher, Shannon L ^a   Kim, Sungeun ^a   Nho, Kwangsik ^a   Foroud, Tatiana ^a,b   Shen, Li ^a   Petersen, Ronald C ^c   Jack, Clifford R ^c   Beckett, Laurel A ^d   Aisen, Paul S ^e   Koeppe, Robert A ^f   Jagust, William J ^g   Shaw, Leslie M ^h   Trojanowski, John Q ^h   Weiner, Michael W ^i,j   Saykin, Andrew J ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF MICHIGAN   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF PENNSYLVANIA   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^k ADNI)

more..

Author keywords

ADNI; Alzheimer's Disease Neuroimaging Initiative; APOE; Apolipoprotein E; Cerebrospinal fluid; CSF; FDG; Neuroimaging; PET; SCD; Significant memory concern; SMC; Structural magnetic resonance imaging (MRI); Subjective cognitive decline; 18F Florbetapir PET; 18F Fluorodeoxyglucose

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN E4; BIOLOGICAL MARKER; FLORBETAPIR F 18; TAU PROTEIN; AMYLOID BETA PROTEIN;

AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN ATROPHY; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID ANALYSIS; FEMALE; GENETIC RISK; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDIAL TEMPORAL LOBE; MEMORY; MEMORY DISORDER; MILD COGNITIVE IMPAIRMENT; NERVE DEGENERATION; NEUROIMAGING; PRIORITY JOURNAL; PROTEIN METABOLISM; SIGNIFICANT MEMORY CONCERN; ADULT; BRAIN; COGNITIVE DYSFUNCTION; GENETICS; GENOTYPE; HETEROZYGOTE; METABOLISM; NEUROPSYCHOLOGICAL TEST; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; APOLIPOPROTEIN E4; BIOMARKERS; BRAIN; COGNITIVE DYSFUNCTION; FEMALE; GENOTYPE; HEALTHY VOLUNTEERS; HETEROZYGOTE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; NEUROPSYCHOLOGICAL TESTS; POSITRON-EMISSION TOMOGRAPHY; TAU PROTEINS;

EID: 84952630386     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2015.03.003     Document Type: Article

References (54)

1. Alzheimer's Association 2014 Alzheimer's disease facts and figures Alzheimers Dement 10 2014 e47 e92
2. R.A. Sperling, P.S. Aisen, L.A. Beckett, D.A. Bennett, S. Craft, A.M. Fagan, and et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimers Dement 7 2011 280 292
3. F. Jessen, R.E. Amariglio, M. van Boxtel, M. Breteler, M. Ceccaldi, G. Chetelat, and et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease Alzheimers Dement 10 2014 844 852
4. A.J. Saykin, H.A. Wishart, L.A. Rabin, R.B. Santulli, L.A. Flashman, J.D. West, and et al. Older adults with cognitive complaints show brain atrophy similar to that of amnestic MCI Neurology 67 2006 834 842
5. R.J. Caselli, K. Chen, D.E. Locke, W. Lee, A. Roontiva, D. Bandy, and et al. Subjective cognitive decline: self and informant comparisons Alzheimers Dement 10 2014 93 98
6. R. Gallassi, F. Oppi, R. Poda, S. Scortichini, M. Stanzani Maserati, G. Marano, and et al. Are subjective cognitive complaints a risk factor for dementia? Neurol Sci 31 2010 327 336
7. K.A. Gifford, D. Liu, Z. Lu, Y. Tripodis, N.G. Cantwell, J. Palmisano, and et al. The source of cognitive complaints predicts diagnostic conversion differentially among nondemented older adults Alzheimers Dement 10 2013 319 327
8. L. Glodzik-Sobanska, B. Reisberg, S. De Santi, J.S. Babb, E. Pirraglia, K.E. Rich, and et al. Subjective memory complaints: presence, severity and future outcome in normal older subjects Dement Geriatr Cogn Disord 24 2007 177 184
9. T.J. Hohman, L.L. Beason-Held, M. Lamar, and S.M. Resnick Subjective cognitive complaints and longitudinal changes in memory and brain function Neuropsychology 25 2011 125 130
10. F. Jessen, B. Wiese, C. Bachmann, S. Eifflaender-Gorfer, F. Haller, H. Kolsch, and et al. Prediction of dementia by subjective memory impairment: effects of severity and temporal association with cognitive impairment Arch Gen Psychiatry 67 2010 414 422
11. F. Jessen, S. Wolfsgruber, B. Wiese, H. Bickel, E. Mosch, H. Kaduszkiewicz, and et al. AD dementia risk in late MCI, in early MCI, and in subjective memory impairment Alzheimers Dement 10 2014 76 83
12. C. Jonker, M.I. Geerlings, and B. Schmand Are memory complaints predictive for dementia? A review of clinical and population-based studies Int J Geriatr Psychiatry 15 2000 983 991
13. T. Nunes, I. Fragata, F. Ribeiro, T. Palma, J. Maroco, J. Cannas, and et al. The outcome of elderly patients with cognitive complaints but normal neuropsychological tests J Alzheimers Dis 19 2010 137 145
14. I.H. Ramakers, P.J. Visser, P. Aalten, J.H. Boesten, J.F. Metsemakers, J. Jolles, and et al. Symptoms of preclinical dementia in general practice up to five years before dementia diagnosis Dement Geriatr Cogn Disord 24 2007 300 306
15. L.M. Reid, and A.M. Maclullich Subjective memory complaints and cognitive impairment in older people Dement Geriatr Cogn Disord 22 2006 471 485
16. B. Reisberg, M.B. Shulman, C. Torossian, L. Leng, and W. Zhu Outcome over seven years of healthy adults with and without subjective cognitive impairment Alzheimers Dement 6 2010 11 24
17. L.L. Chao, S.G. Mueller, S.T. Buckley, K. Peek, S. Raptentsetseng, J. Elman, and et al. Evidence of neurodegeneration in brains of older adults who do not yet fulfill MCI criteria Neurobiol Aging 31 2010 368 377
18. S. Erk, A. Spottke, A. Meisen, M. Wagner, H. Walter, and F. Jessen Evidence of neuronal compensation during episodic memory in subjective memory impairment Arch Gen Psychiatry 68 2011 845 852
19. F. Jessen, L. Feyen, K. Freymann, R. Tepest, W. Maier, R. Heun, and et al. Volume reduction of the entorhinal cortex in subjective memory impairment Neurobiol Aging 27 2006 1751 1756
20. J. Rodda, T. Dannhauser, D.J. Cutinha, S.S. Shergill, and Z. Walker Subjective cognitive impairment: functional MRI during a divided attention task Eur Psychiatry 26 2011 457 462
21. L. Scheef, A. Spottke, M. Daerr, A. Joe, N. Striepens, H. Kolsch, and et al. Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment Neurology 79 2012 1332 1339
22. R. Stewart, O. Godin, F. Crivello, P. Maillard, B. Mazoyer, C. Tzourio, and et al. Longitudinal neuroimaging correlates of subjective memory impairment: 4-year prospective community study Br J Psychiatry 198 2011 199 205
23. N. Striepens, L. Scheef, A. Wind, D. Meiberth, J. Popp, A. Spottke, and et al. Interaction effects of subjective memory impairment and ApoE4 genotype on episodic memory and hippocampal volume Psychol Med 41 2011 1997 2006
24. P.J. Visser, F. Verhey, D.L. Knol, P. Scheltens, L.O. Wahlund, Y. Freund-Levi, and et al. Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study Lancet Neurol 8 2009 619 627
25. Y. Wang, S.L. Risacher, J.D. West, B.C. McDonald, T.R. Magee, M.R. Farlow, and et al. Altered default mode network connectivity in older adults with cognitive complaints and amnestic mild cognitive impairment J Alzheimers Dis 35 2013 751 760
26. Y. Wang, J.D. West, L.A. Flashman, H.A. Wishart, R.B. Santulli, L.A. Rabin, and et al. Selective changes in white matter integrity in MCI and older adults with cognitive complaints Biochim Biophys Acta 1822 2012 423 430
27. L.L. Barnes, J.A. Schneider, P.A. Boyle, J.L. Bienias, and D.A. Bennett Memory complaints are related to Alzheimer disease pathology in older persons Neurology 67 2006 1581 1585
28. L. Mosconi, S. De Santi, M. Brys, W.H. Tsui, E. Pirraglia, L. Glodzik-Sobanska, and et al. Hypometabolism and altered cerebrospinal fluid markers in normal apolipoprotein E E4 carriers with subjective memory complaints Biol Psychiatry 63 2008 609 618
29. C.C. Rowe, K.A. Ellis, M. Rimajova, P. Bourgeat, K.E. Pike, G. Jones, and et al. Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging Neurobiol Aging 31 2010 1275 1283
30. C.R. Jack Jr., D.S. Knopman, W.J. Jagust, R.C. Petersen, M.W. Weiner, P.S. Aisen, and et al. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers Lancet Neurol 12 2013 207 216
31. S.L. Risacher, S. Kim, L. Shen, K. Nho, T. Foroud, R.C. Green, and et al. The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI) Front Aging Neurosci 5 2013 11
32. R.J. Bateman, C. Xiong, T.L. Benzinger, A.M. Fagan, A. Goate, N.C. Fox, and et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease N Engl J Med 367 2012 795 804
33. C.R. Jack Jr., M.A. Bernstein, B.J. Borowski, J.L. Gunter, N.C. Fox, P.M. Thompson, and et al. Update on the magnetic resonance imaging core of the Alzheimer's Disease Neuroimaging Initiative Alzheimers Dement 6 2010 212 220
34. W.J. Jagust, D. Bandy, K. Chen, N.L. Foster, S.M. Landau, C.A. Mathis, and et al. The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core Alzheimers Dement 6 2010 221 229
35. J.Q. Trojanowski, H. Vandeerstichele, M. Korecka, C.M. Clark, P.S. Aisen, R.C. Petersen, and et al. Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects Alzheimers Dement 6 2010 230 238
36. R.C. Petersen, P.S. Aisen, L.A. Beckett, M.C. Donohue, A.C. Gamst, D.J. Harvey, and et al. Alzheimer's Disease Neuroimaging Initiative (ADNI): clinical characterization Neurology 74 2010 201 209
37. A.J. Saykin, L. Shen, T.M. Foroud, S.G. Potkin, S. Swaminathan, S. Kim, and et al. Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans Alzheimers Dement 6 2010 265 273
38. M.W. Weiner, P.S. Aisen, C.R. Jack Jr., W.J. Jagust, J.Q. Trojanowski, L. Shaw, and et al. The Alzheimer's Disease Neuroimaging Initiative: progress report and future plans Alzheimers Dement 6 2010 202 211 e7
39. Brett M, Anton JL, Valabregue R, Poline J-B. Region of interest analysis using an SPM toolbox [abstract]. Presented at the 8th international conference on functional mapping of the human brain, June 2-6, 2002. Sendai, Japan 2002.
40. C.R. Jack Jr., M.A. Bernstein, N.C. Fox, P. Thompson, G. Alexander, D. Harvey, and et al. The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods J Magn Reson Imaging 27 2008 685 691
41. A. Dale, B. Fischl, and M. Sereno Cortical surface-based analysis. I. Segmentation and surface reconstruction Neuroimage 9 1999 179 194
42. B. Fischl, M. Sereno, and A. Dale Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system Neuroimage 9 1999 195 207
43. L.M. Shaw, H. Vanderstichele, M. Knapik-Czajka, M. Figurski, E. Coart, K. Blennow, and et al. Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI Acta Neuropathol 121 2011 597 609
44. L.M. Shaw, H. Vanderstichele, M. Knapik-Czajka, C.M. Clark, P.S. Aisen, R.C. Petersen, and et al. Cerebrospinal fluid biomarker signature in Alzheimer's disease Neuroimaging Initiative subjects Ann Neurol 65 2009 403 413
45. S.M. Landau, C. Breault, A.D. Joshi, M. Pontecorvo, C.A. Mathis, W.J. Jagust, and et al. Amyloid-beta imaging with Pittsburgh compound B and florbetapir: comparing radiotracers and quantification methods J Nucl Med 54 2013 70 77
46. C.D. Smith, A.H. Andersen, and B.T. Gold Structural brain alterations before mild cognitive impairment in ADNI: validation of volume loss in a predefined antero-temporal region J Alzheimers Dis 31 Suppl 3 2012 S49 S58
47. N. Striepens, L. Scheef, A. Wind, J. Popp, A. Spottke, D. Cooper-Mahkorn, and et al. Volume loss of the medial temporal lobe structures in subjective memory impairment Dement Geriatr Cogn Disord 29 2010 75 81
48. W.J. Jagust, S.M. Landau Alzheimer's Disease Neuroimaging I Apolipoprotein E, not fibrillar beta-amyloid, reduces cerebral glucose metabolism in normal aging J Neurosci 32 2012 18227 18233
49. H.A. Wishart, A.J. Saykin, T.W. McAllister, L.A. Rabin, B.C. McDonald, L.A. Flashman, and et al. Regional brain atrophy in cognitively intact adults with a single APOE epsilon4 allele Neurology 67 2006 1221 1224
50. T. Espeseth, L.T. Westlye, A.M. Fjell, K.B. Walhovd, H. Rootwelt, and I. Reinvang Accelerated age-related cortical thinning in healthy carriers of apolipoprotein E epsilon 4 Neurobiol Aging 29 2008 329 340
51. J. Fortea, R. Sala-Llonch, D. Bartres-Faz, A. Llado, C. Sole-Padulles, B. Bosch, and et al. Cognitively preserved subjects with transitional cerebrospinal fluid ss-amyloid 1-42 values have thicker cortex in Alzheimer's disease vulnerable areas Biol Psychiatry 70 2011 183 190
52. J. Fortea, R. Sala-Llonch, D. Bartres-Faz, B. Bosch, A. Llado, N. Bargallo, and et al. Increased cortical thickness and caudate volume precede atrophy in PSEN1 mutation carriers J Alzheimers Dis 22 2010 909 922
53. D.T. Chien, A.K. Szardenings, S. Bahri, J.C. Walsh, F. Mu, C. Xia, and et al. Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808 J Alzheimers Dis 38 2014 171 184
54. M. Maruyama, H. Shimada, T. Suhara, H. Shinotoh, B. Ji, J. Maeda, and et al. Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls Neuron 79 2013 1094 1108