Release of insulin from PLGA-alginate dressing stimulates regenerative healing of burn wounds in rats

Clinical Science

Volumn 129, Issue 12, 2015, Pages 1115-1129

  Dhall, Sandeep ^a   Silva, João P ^a,b   Liu, Yan ^a,c   Hrynyk, Michael ^d   Garcia, Monika ^a   Chan, Alex ^a   Lyubovitsky, Julia ^e   Neufeld, Ronald J ^d   Martins Green, Manuela ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MINHO   (Portugal)

^c SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^d QUEEN S UNIVERSITY   (Canada)

^e University of California Riverside   (United States)

Author keywords

Angiogenesis; Burn healing; Collagen; Insulin; Macrophage; Neutrophils; Oxidative stress

Indexed keywords

ALGINIC ACID; GLUCOSE; INSULIN; POLYGLACTIN; REACTIVE OXYGEN METABOLITE; AUTACOID; COLLAGEN; CYTOKINE; DRUG CARRIER; HUMAN INSULIN; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ADULT; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL LOAD; BODY WEIGHT; BURN; CIRCADIAN RHYTHM; COLLAGEN FIBER; CONTROLLED STUDY; FEMALE; FOAM DRESSING; GLUCOSE BLOOD LEVEL; INFLAMMATION; INSULIN RELEASE; INSULIN TREATMENT; LIPID PEROXIDATION; MACROPHAGE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REGENERATIVE MEDICINE; SCAR FORMATION; SUSTAINED DRUG RELEASE; WOUND DRESSING; WOUND HEALING; ANIMAL; BANDAGE; BURNS; CHEMISTRY; CICATRIX; DISEASE MODEL; DRUG EFFECTS; HUMAN; INTRADERMAL DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; METABOLISM; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PATHOPHYSIOLOGY; SKIN; SOLUBILITY; SPRAGUE DAWLEY RAT; TIME; VASCULARIZATION;

ADMINISTRATION, CUTANEOUS; ALGINATES; ANIMALS; BANDAGES; BURNS; CHEMISTRY, PHARMACEUTICAL; CICATRIX; COLLAGEN; CYTOKINES; DISEASE MODELS, ANIMAL; DRUG CARRIERS; FEMALE; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INSULIN, REGULAR, HUMAN; LACTIC ACID; NEOVASCULARIZATION, PHYSIOLOGIC; NEUTROPHIL INFILTRATION; OXIDATIVE STRESS; POLYGLYCOLIC ACID; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SKIN; SOLUBILITY; TIME FACTORS; WOUND HEALING;

EID: 84952032216     PISSN: 01435221     EISSN: 14708736     Source Type: Journal    
DOI: 10.1042/CS20150393     Document Type: Article

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