-
1
-
-
0027179476
-
Homozygous deletion of the human insulin receptor gene results in leprechaunism
-
DOI 10.1038/ng0993-71
-
Wertheimer E, Lu SP, Backeljauw PF, Davenport ML, Taylor SI. Homozygous deletion of the human insulin receptor gene results in leprechaunism. Nat Genet 1993; 5:71-73 (Pubitemid 23261522)
-
(1993)
Nature Genetics
, vol.5
, Issue.1
, pp. 71-73
-
-
Wertheimer, E.1
Lu, S.-P.2
Backeljauw, P.F.3
Davenport, M.L.4
Taylor, S.I.5
-
2
-
-
0025813375
-
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
-
Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA, et al. Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 1991; 352:73-77 (Pubitemid 21896701)
-
(1991)
Nature
, vol.352
, Issue.6330
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.A.6
Cahill, D.A.7
Goldstein, B.J.8
White, M.F.9
-
3
-
-
0027177288
-
Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes
-
Chuang LM, Myers MG Jr, Seidner GA, Birnbaum MJ, White MF, Kahn CR. Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes. Proc Natl Acad Sci USA 1993; 90:5172-5175 (Pubitemid 23182999)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.11
, pp. 5172-5175
-
-
Chuang, L.-M.1
Myers Jr., M.G.2
Seidner, G.A.3
Birnbaum, M.J.4
White, M.F.5
Kahn, C.R.6
-
4
-
-
0028085078
-
The insulin signaling system
-
White MF, Kahn CR. The insulin signaling system. J Biol Chem 1994; 269:1-4.
-
(1994)
J Biol Chem
, vol.269
, pp. 1-4
-
-
White, M.F.1
Kahn, C.R.2
-
5
-
-
0027507755
-
IRS-1: Essential for insulin- And IL-4-stimulated mitogenesis in hematopoietic cells
-
Wang LM, Myers MG Jr, Sun XJ, Aaronson SA, White M, Pierce JH. IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells. Science 1993; 261:1591-1594 (Pubitemid 23319604)
-
(1993)
Science
, vol.261
, Issue.5128
, pp. 1591-1594
-
-
Wang, L.-M.1
Myers Jr., M.G.2
Sun, X.-J.3
Aaronson, S.A.4
White, M.5
Pierce, J.H.6
-
8
-
-
0024335386
-
Cytosolic free calcium in adipocytes. Distinct mechanisms of regulation and effects on insulin action
-
Kelly KL, Deeney JT, Corkey BE. Cytosolic free calcium in adipocytes. Distinct mechanisms of regulation and effects on insulin action. J Biol Chem 1989; 264:12754-12757 (Pubitemid 19194840)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.22
, pp. 12754-12757
-
-
Kelly, K.L.1
Deeney, J.T.2
Corkey, B.E.3
-
9
-
-
0023161576
-
2+ during differentiation of 3T3-L1 adipocytes. Effect of insulin and relation to glucose transport
-
2+ during differentiation of 3T3-L1 adipocytes. Effect of insulin and relation to glucose transport. J Biol Chem 1987; 262:9141-9146
-
(1987)
J Biol Chem
, vol.262
, pp. 9141-9146
-
-
Klip, A.1
Ramlal, T.2
-
11
-
-
4444280868
-
IGF-I and insulin induce different intracellular calcium signals in skeletal muscle cells
-
DOI 10.1677/joe.0.1820339
-
Espinosa A, Estrada M, Jaimovich E. IGF-I and insulin induce different intracellular calcium signals in skeletal muscle cells. J Endocrinol 2004; 182:339-352 (Pubitemid 39199017)
-
(2004)
Journal of Endocrinology
, vol.182
, Issue.2
, pp. 339-351
-
-
Espinosa, A.1
Estrada, M.2
Jaimovich, E.3
-
13
-
-
0032577464
-
Association of the insulin receptor with phospholipase C-gamma/(PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin
-
DOI 10.1074/jbc.273.22.13808
-
Kayali AG, Eichhorn J, Haruta T, Morris AJ, Nelson JG, Vollenweider P, et al. Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin. J Biol Chem 1998; 273:13808-13818 (Pubitemid 28268431)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.22
, pp. 13808-13818
-
-
Kayali, A.G.1
Eichhorn, J.2
Haruta, T.3
Morris, A.J.4
Nelson, J.G.5
Vollenweider, P.6
Olefsky, J.M.7
Webster, N.J.G.8
-
14
-
-
85047682231
-
PLC-gamma1 enzyme activity is required for insulin-induced DNA synthesis
-
DOI 10.1210/en.143.2.655
-
Eichhorn J, Kayali AG, Resor L, Austin DA, Rose DW, Webster NJ. PLC-gamma1 enzyme activity is required for insulin-induced DNA synthesis. Endocrinology 2002; 143:655-664 (Pubitemid 34107221)
-
(2002)
Endocrinology
, vol.143
, Issue.2
, pp. 655-664
-
-
Eichhorn, J.1
Kayali, A.G.2
Resor, L.3
Austin, D.A.4
Rose, D.W.5
Webster, N.J.G.6
-
15
-
-
0034464863
-
Regulatory cascades involving calmodulin-dependent protein kinases
-
DOI 10.1210/me.14.1.4
-
Means AR. Regulatory cascades involving calmodulin-dependent protein kinases. Mol Endocrinol 2000; 14:4-13. (Pubitemid 32260324)
-
(2000)
Molecular Endocrinology
, vol.14
, Issue.1
, pp. 4-13
-
-
Means, A.R.1
-
16
-
-
0027981633
-
Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression
-
Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, McKnight GS. Calcium/ calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Mol Cell Biol 1994; 14:6107-6116 (Pubitemid 24264440)
-
(1994)
Molecular and Cellular Biology
, vol.14
, Issue.9
, pp. 6107-6116
-
-
Matthews, R.P.1
Guthrie, C.R.2
Wailes, L.M.3
Zhao, X.4
Means, A.R.5
Mcknight, G.S.6
-
17
-
-
0242413666
-
Calcium/Calmodulin-dependent Protein Kinase II Binds to Raf-1 and Modulates Integrin-stimulated ERK Activation
-
DOI 10.1074/jbc.M305355200
-
Illario M, Cavallo AL, Bayer KU, Di Matola T, Fenzi G, Rossi G, Vitale M. Calcium/ calmodulin-dependent protein kinase II binds to Raf-1 and modulates integrin-stimulated ERK activation. J Biol Chem 2003; 278:45101-45108 (Pubitemid 37432642)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.46
, pp. 45101-45108
-
-
Illario, M.1
Cavallo, A.L.2
Bayer, K.U.3
Di Matola, T.4
Fenzi, G.5
Rossi, G.6
Vitale, M.7
-
18
-
-
21044451564
-
Fibronectininduced proliferation in thyroid cells is mediated by {alpha}v{beta}3 integrin through Ras/Raf-1/MEK/ERK and calcium/CaMKII signals
-
Illario M, Cavallo AL, Monaco S, Di Vito E, Mueller F, Marzano LA, et al. Fibronectininduced proliferation in thyroid cells is mediated by {alpha}v{beta}3 integrin through Ras/Raf-1/MEK/ERK and calcium/CaMKII signals. J Clin Endocrinol Metab 2005; 90:2865-2873
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 2865-2873
-
-
Illario, M.1
Cavallo, A.L.2
Monaco, S.3
Di Vito, E.4
Marzano La, M.F.5
-
19
-
-
60549101660
-
Calcium-calmodulin-dependent kinase II (CaMKII) mediates insulin-stimulated proliferation and glucose uptake
-
Illario M, Monaco S, Cavallo AL, Esposito I, Formisano P, D'Andrea L, et al. Calcium-calmodulin-dependent kinase II (CaMKII) mediates insulin-stimulated proliferation and glucose uptake. Cell Signal 2009; 21:786-792
-
(2009)
Cell Signal
, vol.21
, pp. 786-792
-
-
Illario, M.1
Monaco, S.2
Cavallo, A.L.3
Esposito, I.4
Formisano, P.5
D'Andrea, L.6
-
20
-
-
20244376007
-
Effect of granulocyte macrophage-colony stimulating factor on extracellular matrix deposition by dermal fibroblasts from patients with scleroderma
-
Postiglione L, Ladogana P, Montagnani S, di Spigna G, Castaldo C, Turano M, et al. Effect of granulocyte macrophage-colony stimulating factor on extracellular matrix deposition by dermal fibroblasts from patients with scleroderma. J Rheumatol 2005; 32:656-664 (Pubitemid 40524697)
-
(2005)
Journal of Rheumatology
, vol.32
, Issue.4
, pp. 656-664
-
-
Postiglione, L.1
Ladogana, P.2
Montagnani, S.3
Di Spigna, G.4
Castaldo, C.5
Turano, M.6
Bruno, E.M.7
Di Meglio, F.8
Riccio, A.9
Rossi, G.10
-
22
-
-
42449109515
-
Insulin stimulates primary beta-cell proliferation via Raf-1 kinase
-
DOI 10.1210/en.2007-1557
-
Beith JL, Alejandro EU, Johnson JD. Insulin stimulates primary beta-cell proliferation via Raf-1 kinase. Endocrinology 2008; 149:2251-2260 (Pubitemid 351574508)
-
(2008)
Endocrinology
, vol.149
, Issue.5
, pp. 2251-2260
-
-
Beith, J.L.1
Alejandro, E.U.2
Johnson, J.D.3
-
23
-
-
38349109606
-
Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis
-
Alejandro EU, Johnson JD. Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. J Biol Chem 2008; 283:2407-2417
-
(2008)
J Biol Chem
, vol.283
, pp. 2407-2417
-
-
Alejandro, E.U.1
Johnson, J.D.2
-
24
-
-
0028965111
-
Biochemical analysis of MEK activation in NIH3T3 fibroblasts. Identification of B-Raf and other activators
-
Reuter CW, Catling AD, Jelinek T, Weber MJ. Biochemical analysis of MEK activation in NIH3T3 fibroblasts. Identification of B-Raf and other activators. J Biol Chem 1995; 270:7644-7655
-
(1995)
J Biol Chem
, vol.270
, pp. 7644-7655
-
-
Reuter, C.W.1
Catling, A.D.2
Jelinek, T.3
Weber, M.J.4
-
25
-
-
0023820505
-
2+ and pH responses to sequential additions of mitogens in single 3T3 fibroblasts: Correlations with DNA synthesis
-
Hesketh TR, Morris JD, Moore JP, Metcalfe JC. Ca2+ and pH responses to sequential additions of mitogens in single 3T3 fibroblasts: correlations with DNA synthesis. J Biol Chem 1988; 263:11879-11886 (Pubitemid 18212252)
-
(1988)
Journal of Biological Chemistry
, vol.263
, Issue.24
, pp. 11879-11886
-
-
Hesketh, T.R.1
Morris, J.D.H.2
Moore, J.P.3
Metcalfe, J.C.4
-
27
-
-
33845906409
-
A purine analog kinase inhibitor, calcium/calmodulin-dependent protein kinase II inhibitor 59, reveals a role for calcium/calmodulin-dependent protein kinase II in insulin-stimulated glucose transport
-
DOI 10.1210/en.2006-0446
-
Konstantopoulos N, Marcuccio S, Kyi S, Stoichevska V, Castelli LA, Ward CW, et al. A purine analog kinase inhibitor, calcium/calmodulin-dependent protein kinase II inhibitor 59, reveals a role for calcium/calmodulin-dependent protein kinase II in insulinstimulated glucose transport. Endocrinology 2007; 148:374-385 (Pubitemid 46021470)
-
(2007)
Endocrinology
, vol.148
, Issue.1
, pp. 374-385
-
-
Konstantopoulos, N.1
Marcuccio, S.2
Kyi, S.3
Stoichevska, V.4
Castelli, L.A.5
Ward, C.W.6
Macaulay, S.L.7
-
29
-
-
0031041171
-
Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic Ras and tyrosine kinases
-
DOI 10.1074/jbc.272.7.4378
-
Marais R, Light Y, Paterson HF, Mason CS, Marshall CJ. Differential regulation of Raf-1, A-Raf and B-Raf by oncogenic ras and tyrosine kinases. J Biol Chem 1997; 272:4378-4383 (Pubitemid 27078513)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.7
, pp. 4378-4383
-
-
Marais, R.1
Light, Y.2
Paterson, H.F.3
Mason, C.S.4
Marshall, C.J.5
-
30
-
-
0037400510
-
Mechanisms of regulating the Raf kinase family
-
DOI 10.1016/S0898-6568(02)00139-0
-
Chong H, Vikis HG, Guan KL. Mechanisms of regulating the Raf kinase family. Cell Signal 2003; 15:463-469 (Pubitemid 36292166)
-
(2003)
Cellular Signalling
, vol.15
, Issue.5
, pp. 463-469
-
-
Chong, H.1
Vikis, H.G.2
Guan, K.-L.3
-
31
-
-
55849152355
-
Aging: ROS or TOR
-
Blagosklonny MV. Aging: ROS or TOR. Cell Cycle 2008; 7:3344-3354
-
(2008)
Cell Cycle
, vol.7
, pp. 3344-3354
-
-
Blagosklonny, M.V.1
-
32
-
-
50549087736
-
Growth stimulation leads to cellular senescence when the cell cycle is blocked
-
Demidenko ZN, Blagosklonny MV. Growth stimulation leads to cellular senescence when the cell cycle is blocked. Cell Cycle 2008; 7:3355-3361
-
(2008)
Cell Cycle
, vol.7
, pp. 3355-3361
-
-
Demidenko, Z.N.1
Blagosklonny, M.V.2
-
33
-
-
37149029370
-
Calcium signaling
-
Clapham DE. Calcium signaling. Cell 2007; 131:1047-1058
-
(2007)
Cell
, vol.131
, pp. 1047-1058
-
-
Clapham, D.E.1
-
34
-
-
0037341276
-
Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: Potential role of p38 in the downregulation of GLUT4 expression
-
DOI 10.2337/diabetes.52.3.634
-
Carlson CJ, Koterski S, Sciotti RJ, Poccard GB, Rondinone CM. Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression. Diabetes 2003; 52:634-641 (Pubitemid 36323568)
-
(2003)
Diabetes
, vol.52
, Issue.3
, pp. 634-641
-
-
Carlson, C.J.1
Koterski, S.2
Sciotti, R.J.3
Poccard, G.B.4
Rondinone, C.M.5
|