Disease-Dependent Local IL-10 Production Ameliorates Collagen Induced Arthritis in Mice

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Henningsson, Louise ^a   Eneljung, Tove ^a   Jirholt, Pernilla ^a   Tengvall, Sara ^a   Lidberg, Ulf ^b   van den Berg, Wim B ^c   van de Loo, Fons A ^c   Gjertsson, Inger ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN ANTIBODY; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 6; MESSENGER RNA; SUPPRESSOR OF CYTOKINE SIGNALING 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTHRITIS; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; IMMUNOREGULATION; INTERLEUKIN 10 GENE; LENTIVIRINAE; LYMPH NODE; LYMPHOCYTE COUNT; MALE; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN BLOOD LEVEL; VIRUS PARTICLE;

ANIMALS; ANTIBODIES; ARTHRITIS, EXPERIMENTAL; B-LYMPHOCYTES; CELL LINE; COLLAGEN TYPE II; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GENETIC VECTORS; HUMANS; INTERLEUKIN-10; LENTIVIRUS; LYMPH NODES; MALE; MICE; SPLEEN; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; T-LYMPHOCYTES;

MUS;

EID: 84869211131     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049731     Document Type: Article

References (35)

1. ten Wolde S, Breedveld FC, Hermans J, Vandenbroucke JP, van de Laar MA, et al. (1996) Randomised placebo-controlled study of stopping second-line drugs in rheumatoid arthritis. Lancet 347: 347-352.
2. Mathisen PM, Yu M, Johnson JM, Drazba JA, Tuohy VK, (1997) Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells. The Journal of experimental medicine 186: 159-164.
3. Geurts J, Arntz OJ, Bennink MB, Joosten LA, van den Berg WB, et al. (2007) Application of a disease-regulated promoter is a safer mode of local IL-4 gene therapy for arthritis. Gene therapy 14: 1632-1638.
4. Sabat R, Grutz G, Warszawska K, Kirsch S, Witte E, et al. (2010) Biology of interleukin-10. Cytokine & growth factor reviews 21: 331-344.
5. Kasama T, Strieter RM, Lukacs NW, Lincoln PM, Burdick MD, et al. (1995) Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis. The Journal of clinical investigation 95: 2868-2876.
6. Finnegan A, Kaplan CD, Cao Y, Eibel H, Glant TT, et al. (2003) Collagen-induced arthritis is exacerbated in IL-10-deficient mice. Arthritis research & therapy 5: R18-24.
7. Joosten LA, Lubberts E, Durez P, Helsen MM, Jacobs MJ, et al. (1997) Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis and rheumatism 40: 249-260.
8. Tarner IH, Slavin AJ, McBride J, Levicnik A, Smith R, et al. (2003) Treatment of autoimmune disease by adoptive cellular gene therapy. Annals of the New York Academy of Sciences 998: 512-519.
9. Jorgensen C, Apparailly F, Couret I, Canovas F, Jacquet C, et al. (1998) Interleukin-4 and interleukin-10 are chondroprotective and decrease mononuclear cell recruitment in human rheumatoid synovium in vivo. Immunology 93: 518-523.
10. Apparailly F, Verwaerde C, Jacquet C, Auriault C, Sany J, et al. (1998) Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis. Journal of immunology 160: 5213-5220.
11. Miyata M, Sasajima T, Sato H, Saito A, Iriswa A, et al. (2000) Suppression of collagen induced arthritis in mice utilizing plasmid DNA encoding interleukin 10. The Journal of rheumatology 27: 1601-1605.
12. Garaulet G, Alfranca A, Torrente M, Escolano A, Lopez-Fontal R, et al. (2012) IL10 Released by a New Inflammation-regulated Lentiviral System Efficiently Attenuates Zymosan-induced Arthritis. Molecular therapy: the journal of the American Society of Gene Therapy.
13. van de Loo FA, de Hooge AS, Smeets RL, Bakker AC, Bennink MB, et al. (2004) An inflammation-inducible adenoviral expression system for local treatment of the arthritic joint. Gene Ther 11: 581-590.
14. Palmer DC, Restifo NP, (2009) Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function. Trends in immunology 30: 592-602.
15. Ding Y, Chen D, Tarcsafalvi A, Su R, Qin L, et al. (2003) Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses. Journal of immunology 170: 1383-1391.
16. Diehl S, Anguita J, Hoffmeyer A, Zapton T, Ihle JN, et al. (2000) Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1. Immunity 13: 805-815.
17. Mauri C, (2010) Regulation of immunity and autoimmunity by B cells. Current opinion in immunology 22: 761-767.
18. Mauri C, Gray D, Mushtaq N, Londei M, (2003) Prevention of arthritis by interleukin 10-producing B cells. J Exp Med 197: 489-501.
19. Walmsley M, Katsikis PD, Abney E, Parry S, Williams RO, et al. (1996) Interleukin-10 inhibition of the progression of established collagen-induced arthritis. Arthritis and rheumatism 39: 495-503.
20. Walmsley M, Katsikis PD, Abney E, Parry S, Williams RO, et al. (1996) Interleukin-10 inhibition of the progression of established collagen-induced arthritis. Arthritis Rheum 39: 495-503.
21. Kuroda T, Maruyama H, Shimotori M, Higuchi N, Kameda S, et al. (2006) Effects of viral interleukin 10 introduced by in vivo electroporation on arthrogen-induced arthritis in mice. The Journal of rheumatology 33: 455-462.
22. Fillatreau S, Sweenie CH, McGeachy MJ, Gray D, Anderton SM, (2002) B cells regulate autoimmunity by provision of IL-10. Nat Immunol 3: 944-950.
23. Hashizume M, Mihara M, (2011) The roles of interleukin-6 in the pathogenesis of rheumatoid arthritis. Arthritis 2011: 765624.
24. Kimura A, Naka T, Muta T, Takeuchi O, Akira S, et al. (2005) Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT. Proceedings of the National Academy of Sciences of the United States of America 102: 17089-17094.
25. Egan PJ, Lawlor KE, Alexander WS, Wicks IP, (2003) Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation. The Journal of clinical investigation 111: 915-924.
26. Veenbergen S, Bennink MB, Affandi AJ, Bessis N, Biton J, et al. (2011) A pivotal role for antigen-presenting cells overexpressing SOCS3 in controlling invariant NKT cell responses during collagen-induced arthritis. Annals of the rheumatic diseases 70: 2167-2175.
27. Yoshimura A, Muto G, (2011) TGF-beta function in immune suppression. Current topics in microbiology and immunology 350: 127-147.
28. Prochazkova J, Pokorna K, Holan V, (2012) IL-12 inhibits the TGF-beta-dependent T cell developmental programs and skews the TGF-beta-induced differentiation into a Th1-like direction. Immunobiology 217: 74-82.
29. Luckheeram RV, Zhou R, Verma AD, Xia B, (2012) CD4(+)T cells: differentiation and functions. Clinical & developmental immunology 2012: 925135.
30. Shimizu S, Hirano T, Yoshioka R, Sugai S, Matsuda T, et al. (1988) Interleukin-6 (B-cell stimulatory factor 2)-dependent growth of a Lennert's lymphoma-derived T-cell line (KT-3). Blood 72: 1826-1828.
31. Buch MH, Smolen JS, Betteridge N, Breedveld FC, Burmester G, et al. (2011) Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis. Annals of the rheumatic diseases 70: 909-920.
32. Wright HL, Bucknall RC, Moots RJ, Edwards SW (2011) Analysis of SF and plasma cytokines provides insights into the mechanisms of inflammatory arthritis and may predict response to therapy. Rheumatology.
33. Neidhart M, Jungel A, Ospelt C, Michel BA, Gay RE, et al. (2005) Deficient expression of interleukin-10 receptor alpha chain in rheumatoid arthritis synovium: limitation of animal models of inflammation. Arthritis and rheumatism 52: 3315-3318.
34. van Roon J, Wijngaarden S, Lafeber FP, Damen C, van de Winkel J, et al. (2003) Interleukin 10 treatment of patients with rheumatoid arthritis enhances Fc gamma receptor expression on monocytes and responsiveness to immune complex stimulation. The Journal of rheumatology 30: 648-651.
35. Perfetto SP, Chattopadhyay PK, Roederer M, (2004) Seventeen-colour flow cytometry: unravelling the immune system. Nat Rev Immunol 4: 648-655.