High-throughput log Po/w determination from UHPLC measurements: Revisiting the chromatographic hydrophobicity index

Journal of Pharmaceutical and Biomedical Analysis

Volumn 127, Issue , 2016, Pages 26-31

  Subirats, Xavier ^a   Rosés, Martí ^a   Bosch, Elisabeth ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

CHI; Chromatographic hydrophobicity index; Lipophilicity; Log Po w; Molecular descriptors; Partition coefficient; Partition ratio

Indexed keywords

ACIDITY; ARTICLE; CHROMATOGRAPHIC HYDROPHOBICITY INDEX; CORRELATION COEFFICIENT; HIGH THROUGHPUT SCREENING; HYDROGEN BOND; HYDROPHOBICITY; LIPOPHILICITY; LOGARITHM OF THE 1 OCTANOL WATER PARTITION COEFFICIENT; PARTITION COEFFICIENT; PRIORITY JOURNAL; SOLVATION; SURFACE AREA; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; CHEMICAL MODEL; CHEMICAL PHENOMENA; CHEMISTRY; DEVICES; DRUG DEVELOPMENT; LIQUID CHROMATOGRAPHY; PROCEDURES;

DRUG;

CHROMATOGRAPHY, LIQUID; DRUG DISCOVERY; HIGH-THROUGHPUT SCREENING ASSAYS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS;

EID: 84951794207     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2015.12.015     Document Type: Article

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