Half-sandwich rhodium(III) transfer hydrogenation catalysts: Reduction of NAD+ and pyruvate, and antiproliferative activity

Journal of Inorganic Biochemistry

Volumn 153, Issue , 2015, Pages 322-333

  Soldevila Barreda, Joan J ^a   Habtemariam, Abraha ^a   Romero Canelón, Isolda ^a   Sadler, Peter J ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Anticancer; NAD+; NADH; Organo rhodium; Pyruvate; Transfer hydrogenation

Indexed keywords

1 BIPHENYL 2,3,4,5 TETRAMETHYL CYCLOPENTADIENYL; 1 PHENYL 2,3,4,5 TETRAMETHYLCYCLOPENTADIENYL; 1,10 PHENANTHROLINE; 2,2' BIPYRIDINE; BENZENESULFONAMIDE DERIVATIVE; ETHYLENEDIAMINE; FORMIC ACID; LACTATE DEHYDROGENASE; LACTIC ACID; N (2 AMINOETHYL) 4 (TRIFLUOROMETHYL)BENZENESULFONAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PENTAMETHYLCYCLOPENTADIENYL; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RHODIUM COMPLEX; RHODIUM III COMPLEX; UNCLASSIFIED DRUG; COORDINATION COMPOUND; FORMIC ACID DERIVATIVE; PYRUVIC ACID DERIVATIVE; RHODIUM;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CATALYST; DRUG COMPETITION; DRUG HYDROLYSIS; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; HYDROGENATION; IN VIVO STUDY; INVESTIGATIVE PROCEDURES; LACTATE DEHYDROGENASE BLOOD LEVEL; OVARIAN CANCER CELL LINE; PROTON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; OXIDATION REDUCTION REACTION; TUMOR CELL LINE;

CATALYSIS; CELL LINE, TUMOR; CELL PROLIFERATION; COORDINATION COMPLEXES; FORMATES; HUMANS; HYDROGENATION; LACTIC ACID; NAD; OXIDATION-REDUCTION; PYRUVATES; RHODIUM;

EID: 84951567825     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2015.10.008     Document Type: Article

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