Immunization with amodiaquine-modified hepatic proteins prevents amodiaquine-induced liver injury

Journal of Immunotoxicology

Volumn 12, Issue 4, 2015, Pages 361-367

  Mak, Alastair ^a   Uetrecht, Jack ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Adjuvant; animal model; drug induced liver injury; idiosyncratic adverse drug reaction; reactive metabolite

Indexed keywords

ALANINE AMINOTRANSFERASE; AMODIAQUINE; AMODIAQUINE MODIFIED PROTEIN S 100; COVAX; IMMUNOLOGICAL ADJUVANT; PROTEIN S 100; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CONTROLLED STUDY; COVALENT BOND; DISEASE EXACERBATION; FEMALE; FLOW CYTOMETRY; FOOD INTAKE; IDIOSYNCRATIC DRUG INDUCED LIVER INJURY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; LIVER PROTECTION; LIVER TOXICITY; MACROPHAGE; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; SUPPRESSOR CELL; T LYMPHOCYTE; ANIMAL; CELLULAR IMMUNITY; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; HUMAN; IMMUNOLOGY; LIVER; PATHOLOGY;

ANIMALIA; MUS;

AMODIAQUINE; ANIMALS; DRUG-INDUCED LIVER INJURY; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNITY, CELLULAR; IMMUNIZATION; LIVER; MACROPHAGES; MICE; T-LYMPHOCYTES;

EID: 84938892839     PISSN: 1547691X     EISSN: 15476901     Source Type: Journal    
DOI: 10.3109/1547691X.2014.983660     Document Type: Article

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