Recurring DNA copy number gain at chromosome 9p13 plays a role in the activation of multiple candidate oncogenes in progressing oral premalignant lesions

Cancer Medicine

Volumn 3, Issue 5, 2014, Pages 1170-1184

  Towle, Rebecca ^a   Tsui, Ivy F L ^a,b   Zhu, Yuqi ^a,b   Maclellan, Sara ^a   Poh, Catherine F ^a,b   Garnis, Cathie ^a,b  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

9p13; Copy number gain; Dysplasia; Head and neck cancer; Oncogene; Oral squamous cell carcinoma; Overexpression; Premalignant lesion; Progression

Indexed keywords

VALOSIN CONTAINING PROTEIN;

ARTICLE; CANCER GRADING; CELL PROLIFERATION; CELL VIABILITY; CHROMOSOME 9P; CONTROLLED STUDY; DCTN3 GENE; DNA COPY NUMBER GAIN; FLUORESCENCE IN SITU HYBRIDIZATION; GENE ACTIVATION; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENE OVEREXPRESSION; GENE SILENCING; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MOUTH CANCER; ONCOGENE; ORAL CANCER CELL LINE; ORAL PREMALIGNANT LESION; PHENOTYPE; PRECANCER; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; STOML2 GENE; UPREGULATION; VCP GENE; BIOPSY; CHROMOSOME 9; COPY NUMBER VARIATION; DISEASE COURSE; GENE AMPLIFICATION; GENETICS; MOLECULAR GENETICS; MOUTH TUMOR; PATHOLOGY; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

BIOPSY; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMOSOMES, HUMAN, PAIR 9; DISEASE PROGRESSION; DNA COPY NUMBER VARIATIONS; GENE AMPLIFICATION; GENE EXPRESSION PROFILING; HUMANS; MOLECULAR SEQUENCE DATA; MOUTH NEOPLASMS; ONCOGENES; PHENOTYPE; PRECANCEROUS CONDITIONS; TRANSCRIPTIONAL ACTIVATION;

EID: 84951294941     PISSN: None     EISSN: 20457634     Source Type: Journal    
DOI: 10.1002/cam4.307     Document Type: Article

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