Phytochemical investigation of crude methanol extracts of different species of Swertia from Nepal

BMC Research Notes

Volumn 8, Issue 1, 2015, Pages

  Khanal, Supreet ^a   Shakya, Niroj ^a   Thapa, Krishna ^a   Pant, Deepak Raj ^a  

^a TRIBHUVAN UNIVERSITY   (Nepal)

Author keywords

Amarogentin; Antioxidant; Mangiferin; Swertia species; Swertiamarin; TLC

Indexed keywords

AMAROGENTIN; ANTIOXIDANT; FLAVONOID; IRIDOID; MANGIFERIN; METHANOL; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; POLYPHENOL; PYRONE DERIVATIVE; SCAVENGER; SWERTIAMARIN; XANTHONE DERIVATIVE;

CHEMISTRY; CLASSIFICATION; HUMAN; ISOLATION AND PURIFICATION; MEDICINAL PLANT; NEPAL; SPECIES DIFFERENCE; SWERTIA; THIN LAYER CHROMATOGRAPHY;

ANTIOXIDANTS; CHROMATOGRAPHY, THIN LAYER; FLAVONOIDS; FREE RADICAL SCAVENGERS; HUMANS; IRIDOID GLUCOSIDES; IRIDOIDS; METHANOL; NEPAL; PHYTOCHEMICALS; PLANT EXTRACTS; PLANTS, MEDICINAL; POLYPHENOLS; PYRONES; SPECIES SPECIFICITY; SWERTIA; XANTHONES;

EID: 84951293779     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/s13104-015-1753-0     Document Type: Article

References (39)

1. Dewick PM. Tumor inhibition from plants. Tease and Evans; 1996.
2. Paterson I, Anderson EA. The renaissance of natural products as drug candidates. Science. 2005;310:451-3.
3. Cragg GM, Newman DJ, Snader KM. Natural products in drug discovery and development. J Nat Prod. 1997;60:52-60.
4. Joshi AR, Joshi DP. Endemic plants of Nepal himalaya: conservation status and future direction. Mt Env Develop. 1991;1:1-35.
5. Chaudhary RP. Biodiversity in Nepal: status and conservation. S. Devi, Saharanpur (India) and Tec Press Books, Bankok, 1998.
6. Khanal S, Shakya N, Nepal N, Pant D. Swertia chirayita: the himalayan herb. Intl J Appl Sci Biotech. 2014;2:4.
7. Joshi K. Swertia L. (Gentianaceae) in Nepal: ethnobotany and agenda for sustainable management. Ethnobot Leafl. 2008;12:1-6.
8. Joshi AR, Joshi DP. Endemic plants of Nepal himalaya: conservation status and future direction. Mt Env Dev. 1991;1:1-35.
9. Barakoti TP, Chapagain T, Thapa Y, Bhusal C. Chiraito conservation and cultivation and cultivation workshop and achievement. Pakhribas, Dhankuta, Nepal: Nepal Agriculture Research Centre (NARC); 1999.
10. Phoboo S, Pinto MDS, Bhowmik PC, Jha PK, Shetty K. Quantification of major phytochemicals of Swertia chirayita, a medicinal plant from Nepal. Ecoprint. 2010;17:59-68.
11. Brahmachari G, Mondal S, Gangopadhyay A, Gorai D, Mukhopadhyay B, Saha S, Brahmachari AK. Swertia (Gentianaceae): chemical and pharmacological aspects. Chem Biodiv. 2004;1:1627-51.
12. Negi JS, Singh P, Rawat B. Chemical constituents and biological importance of Swertia: a review. Curr Res Chem. 2011;3:1-15.
13. Harborne JB. Phytochemicals methods. London: Chapman and Hall Ltd.; 1973. p. 49-188.
14. Trease GE, Evans WC. Pharmacognosy. 11th ed. London: Bailliere Tindall; 1989. p. 45-50.
15. Chang C, Yang M, Wen H, Chern J. Estimation of total flavonoid content in propolis by two complementary colorimetric methods. J Food Drug Anal. 2002;10:178-82.
16. Chang LW, Yen WJ, Huang SC, Duh PD. Antioxidant activity of sesame coat. Food Chem. 2002;78:347-54.
17. Blois MS. Antioxidant determinations by the use of a stable free radical. Nature. 1958;181:1199-200.
18. Wagner H, Bladt S, Zgainski EM. Plant drug analysis. Berlin: Springer-Verlag; 1983. p. 1-304.
19. Biochemlabsolutions (2014) http://biochemlabsolutions.com/GelQuantNET.html. Accessed 21 Mar 2014.
20. Baral D, Joshi SD, Manandhar MD. Studies on phytochemical screening of some Swertia species. Plant Resour Bull Dept Plant Resour 2012;34.
21. Middleton E Jr, Kandaswami C, Theoharides TC. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev. 2000;52:673-751.
22. Tripathi R, Mohan H, Kamat JP. Modulation of oxidative damage by natural products. J Food Chem. 2007;100:81-90. doi: 10.1016/j.foodchem.2005.09.012
23. Havsteen BH. The biochemistry and medical significance of the flavonoids. Pharmacol Ther. 2002;96:67-202.
24. Huang D, Ou B, Prior RL. The chemistry behind antioxidant capacity assays. J Agric Food Chem. 2005;53(6):1841-56.
25. Dembinska-Kiec A, Mykkänen O, Kiec-Wilk B, Mykkänen H. Antioxidant phytochemicals against type 2 diabetes. Br J Nutr. 2008;99:ES109-17.
26. Chen Y, Huang B, He J, Han L, Zhan Y, Wang Y. In vitro and in vivo antioxidant effects of the ethanolic extract of Swertia chirayita. J Ethnopharm. 2011;136:309-15.
27. Dutta AK, Gope PS, Makhnoon S, Rahman S, Siddiquee MA, Kabir Y. Effect of solvent extraction on phenolic content, antioxidant and α-amylase inhibition activities of Swertia chiraiyta. Intl J Drug Dev Res. 2012;4:317-25.
28. Schwartz JL. The dual roles of nutrients as antioxidants and pro-oxidants; their effects on tumor cell growth. J Nutr. 1996;126S:1221-7.
29. Chan EWC, Lim YY, Omar M. Antioxidant and antibacterial activity of leaves of Etlingera species (Zingiberaceae) in peninsular Malaysia. Food Chem. 2007;104:1586-93.
30. Hajimehdipoor H, Dijoux-Franca MG, Mariotte AM, Amanzadeh Y, Sadat-Ebrahimi SE, Ghazi-Khansari M, Mozaffarain V. Phytochemical study of Swertia longifolia. DARU. 2008;16:245-9.
31. Nagalekshmi R, Menon A, Chandrasekharan DK, Nair CKK. Hepatoprotective activity of Andrographis paniculata and Swertia chirayita. Food Chem Toxicol. 2011;49:3367-73.
32. Alam KD, Ali MS, Mahjabeen S, Parvin S, Akbar MA, Ahmed R. Analgesic activities of ethanol extract of leaf, stem and their different fractions of Swertia chirayita. Pakistan J Pharm Sci. 2010;23:455-7.
33. Wang D. Qualitative and quantitative analysis of Swertia herbs by high performance liquid chromatography diode array detector-mass spectrometry (HPLC-DAD-MS). Chem Pharm Bull. 2008;56:485-90.
34. Bhattacharya SK, Reddy PKSP, Ghosal S, Singh AK, Sharma PV. Chemical constituents of gentianaceae XIX: CNS-depressant effects of swertiamarin. J Pharm Sci. 1976;65:1547-9.
35. Ray S, Majumder HK, Chakravarty AK, Mukhopadhyay S. Amaraogentin, a naturally occurring secoiridoid glycoside and a newly recognized inhibitor of topoisomerase I from Leishmania donovani. J Nat Prod. 1996;59:27-9.
36. Medda S, Mukhopadhyay S, Basu MK. Evaluation of the in vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms. J Antimicrob Chemother. 1999;44:791-4.
37. Pandey DK, Basu S, Jha TB. Screening of different east himalayan species and populations of Swertia L. based on exomorphology and mangiferin content. Asian Pac J Trop Biomed. 2012;2:S1450-6.
38. Jensen SR, Schripsema J. Chemotaxonomy and pharmacology of gentianaceae. In: Struwe L, Albert V (eds) Gentianaceae-systematics and natural history. Cambridge University Press. 2002, p. 573-631.
39. Andreu P, Colnot S, Godard C, Gad S, Chafey P, Niwa-Kawakita M, Laurent-Puig P, Kahn A, Robine S, Perret C. Cryptrestricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine. Development. 2005;132:1443-5.