β3-Adrenoceptor Impairs Mitochondrial Biogenesis and Energy Metabolism during Rapid Atrial Pacing-Induced Atrial Fibrillation

Journal of Cardiovascular Pharmacology and Therapeutics

Volumn 21, Issue 1, 2016, Pages 114-126

  Dong, Jingmei ^a   Zhao, Jingjing ^a   Zhang, Miaomiao ^a   Liu, Guangzhong ^a   Wang, Xiaobing ^a   Liu, Yixi ^a   Yang, Ning ^a   Liu, Yongwu ^b   Zhao, Guanqi ^a   Sun, Jiayu ^a   Tian, Jingpu ^a   Cheng, Cheping ^c   Wei, Lin ^d   Li, Yue ^a   Li, Weimin ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d First Hospital of Harbin   (China)

Author keywords

atrial fibrillation; metabolic remodeling; mitochondrial biogenesis; 3 adrenoceptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA 2 ADRENERGIC RECEPTOR; CREATINE PHOSPHATE; CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; ADENINE NUCLEOTIDE; ANTIARRHYTHMIC AGENT; BETA 3 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; MITOCHONDRIAL PROTEIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; TRANSCRIPTION FACTOR NRF1;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATRIAL FIBRILLATION; CONTROLLED STUDY; DNA CONTENT; DOWN REGULATION; ENERGY METABOLISM; FEMALE; MALE; MITOCHONDRIAL BIOGENESIS; NEW ZEALAND WHITE (RABBIT); NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING; ANIMAL; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEART ATRIUM FUNCTION; HEART ATRIUM REMODELING; HEART MITOCHONDRION; HEART PACING; HEART RATE; METABOLISM; ORGANELLE BIOGENESIS; PATHOPHYSIOLOGY; RABBIT; TIME FACTOR;

ADENINE NUCLEOTIDES; ADRENERGIC BETA-3 RECEPTOR AGONISTS; ADRENERGIC BETA-3 RECEPTOR ANTAGONISTS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ATRIAL FIBRILLATION; ATRIAL FUNCTION, RIGHT; ATRIAL REMODELING; CARDIAC PACING, ARTIFICIAL; DISEASE MODELS, ANIMAL; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; ENERGY METABOLISM; FEMALE; GENE EXPRESSION REGULATION; HEART RATE; MALE; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; NF-E2-RELATED FACTOR 1; ORGANELLE BIOGENESIS; PHOSPHOCREATINE; PROTON-TRANSLOCATING ATPASES; RABBITS; RECEPTORS, ADRENERGIC, BETA-3; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84951284524     PISSN: 10742484     EISSN: 19404034     Source Type: Journal    
DOI: 10.1177/1074248415590440     Document Type: Article

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