Mitochondrial disruption occurs downstream from β-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: Differential activation of stress and survival pathways

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 11, 2013, Pages 2379-2391

  Branco, Ana F ^a,b   Sampaio, Susana F ^a,b   Wieckowski, Mariusz R ^c   Sardão, Vilma A ^a   Oliveira, Paulo J ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

Adrenergic signaling; Apoptosis; H9c2 myoblasts differentiation; Isoproterenol; Mitochondria

Indexed keywords

BETA ADRENERGIC RECEPTOR; CASPASE 3; CYCLIC AMP; ISOPRENALINE; SUPEROXIDE DISMUTASE; ANTIOXIDANT; BETA 2 ADRENERGIC RECEPTOR; CALCIUM; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; SUPEROXIDE;

ANTIOXIDANT ACTIVITY; ARTICLE; BETA ADRENERGIC STIMULATION; CELL CULTURE; CELL DIFFERENTIATION; CELLULAR STRESS RESPONSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG CYTOTOXICITY; ENZYME ACTIVATION; HEART MUSCLE CELL; MEMBRANE DEPOLARIZATION; OXIDATIVE STRESS; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CELL DEATH; CELL LINE; CELL SURVIVAL; CYTOLOGY; CYTOSOL; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PHYSIOLOGICAL STRESS; RAT; TOXICITY;

ANIMALS; ANTIOXIDANTS; CALCIUM; CASPASE 3; CELL DEATH; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CYCLIC AMP; CYTOSOL; ISOPROTERENOL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; SUPEROXIDES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84883513016     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.08.006     Document Type: Article

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