메뉴 건너뛰기




Volumn 1638, Issue , 2016, Pages 74-87

Potential of GABA-ergic cell therapy for schizophrenia, neuropathic pain, and Alzheimers and Parkinsons diseases

Author keywords

Alzheimers disease; GABA ergic interneurons; Medial ganglionic eminence; Neural cell grafts; Pain; Parkinsons disease; Schizophrenia; Stem cell therapy

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR;

EID: 84951202711     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.09.019     Document Type: Review
Times cited : (51)

References (76)
  • 3
    • 77958023983 scopus 로고    scopus 로고
    • Apolipoprotein E4 causes age- and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice
    • Y. Andrews-Zwilling, N. Bien-Ly, Q. Xu, G. Li, A. Bernardo, S.Y. Yoon, D. Zwilling, T.X. Yan, L. Chen, and Y. Huang Apolipoprotein E4 causes age- and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice J. Neurosci. 30 2010 13707 13717
    • (2010) J. Neurosci. , vol.30 , pp. 13707-13717
    • Andrews-Zwilling, Y.1    Bien-Ly, N.2    Xu, Q.3    Li, G.4    Bernardo, A.5    Yoon, S.Y.6    Zwilling, D.7    Yan, T.X.8    Chen, L.9    Huang, Y.10
  • 5
    • 84855309347 scopus 로고    scopus 로고
    • Genetic and cognitive windows into circuit mechanisms of psychiatric disease
    • P.A. Arguello, and J.A. Gogos Genetic and cognitive windows into circuit mechanisms of psychiatric disease Trends Neurosci. 35 2012 3 13
    • (2012) Trends Neurosci. , vol.35 , pp. 3-13
    • Arguello, P.A.1    Gogos, J.A.2
  • 6
    • 74449087013 scopus 로고    scopus 로고
    • Acetazolamide and midazolam act synergistically to inhibit neuropathic pain
    • M. Asiedu, M.H. Ossipov, K. Kaila, and T.J. Price Acetazolamide and midazolam act synergistically to inhibit neuropathic pain Pain 148 2010 302 308
    • (2010) Pain , vol.148 , pp. 302-308
    • Asiedu, M.1    Ossipov, M.H.2    Kaila, K.3    Price, T.J.4
  • 8
  • 9
    • 84905441131 scopus 로고    scopus 로고
    • Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch
    • J.M. Braz, D. Juarez-Salinas, S.E. Ross, and A.I. Basbaum Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch J. Clin. Invest. 124 2014 3612 3616
    • (2014) J. Clin. Invest. , vol.124 , pp. 3612-3616
    • Braz, J.M.1    Juarez-Salinas, D.2    Ross, S.E.3    Basbaum, A.I.4
  • 10
    • 84931288626 scopus 로고    scopus 로고
    • Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivity
    • J.M. Braz, X. Wang, Z. Guan, J.L. Rubenstein, and A.I. Basbaum Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivity Pain 156 2015 1084 1091
    • (2015) Pain , vol.156 , pp. 1084-1091
    • Braz, J.M.1    Wang, X.2    Guan, Z.3    Rubenstein, J.L.4    Basbaum, A.I.5
  • 11
    • 84911994237 scopus 로고    scopus 로고
    • Treating Parkinsons disease in the 21st century: Can stem cell transplantation compete?
    • P.C. Buttery, and R.A. Barker Treating Parkinsons disease in the 21st century: can stem cell transplantation compete? J. Comp. Neurol. 522 2014 2802 2816
    • (2014) J. Comp. Neurol. , vol.522 , pp. 2802-2816
    • Buttery, P.C.1    Barker, R.A.2
  • 15
    • 0019256571 scopus 로고
    • Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia
    • P. Davies, R. Katzman, and R.D. Terry Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia Nature 288 1980 279 280
    • (1980) Nature , vol.288 , pp. 279-280
    • Davies, P.1    Katzman, R.2    Terry, R.D.3
  • 17
    • 0033600492 scopus 로고    scopus 로고
    • A single intrathecal injection of GABA permanently reverses neuropathic pain after nerve injury
    • M.J. Eaton, M.A. Martinez, and S. Karmally A single intrathecal injection of GABA permanently reverses neuropathic pain after nerve injury Brain Res. 835 1999 334 339
    • (1999) Brain Res. , vol.835 , pp. 334-339
    • Eaton, M.J.1    Martinez, M.A.2    Karmally, S.3
  • 19
    • 33845909301 scopus 로고    scopus 로고
    • Subarachnoid transplant of a human neuronal cell line attenuates chronic allodynia and hyperalgesia after excitotoxic spinal cord injury in the rat
    • M.J. Eaton, S.Q. Wolfe, M. Martinez, M. Hernandez, C. Furst, J. Huang, B.R. Frydel, and O. Gomez-Marin Subarachnoid transplant of a human neuronal cell line attenuates chronic allodynia and hyperalgesia after excitotoxic spinal cord injury in the rat J. Pain 8 2007 33 50
    • (2007) J. Pain , vol.8 , pp. 33-50
    • Eaton, M.J.1    Wolfe, S.Q.2    Martinez, M.3    Hernandez, M.4    Furst, C.5    Huang, J.6    Frydel, B.R.7    Gomez-Marin, O.8
  • 22
    • 79960311058 scopus 로고    scopus 로고
    • A novel alpha-5 GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia
    • K.M. Gill, D.J. Lodge, J.M. Cook, S. Aras, and A.A. Grace A novel alpha-5 GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia Neuropsychopharmacology 36 2011 1903 1911
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1903-1911
    • Gill, K.M.1    Lodge, D.J.2    Cook, J.M.3    Aras, S.4    Grace, A.A.5
  • 23
    • 34247517910 scopus 로고    scopus 로고
    • Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
    • A.A. Grace, S.B. Floresco, Y. Goto, and D.J. Lodge Regulation of firing of dopaminergic neurons and control of goal-directed behaviors Trends Neurosci. 30 2007 220 227
    • (2007) Trends Neurosci. , vol.30 , pp. 220-227
    • Grace, A.A.1    Floresco, S.B.2    Goto, Y.3    Lodge, D.J.4
  • 24
    • 0032500857 scopus 로고    scopus 로고
    • Loss of somatostatin-like immunoreactivity in the frontal cortex of Alzheimer patients carrying the apolipoprotein epsilon 4 allele
    • D. Grouselle, R. Winsky-Sommerer, J.P. David, A. Delacourte, P. Dournaud, and J. Epelbaum Loss of somatostatin-like immunoreactivity in the frontal cortex of Alzheimer patients carrying the apolipoprotein epsilon 4 allele Neurosci. Lett. 255 1998 21 24
    • (1998) Neurosci. Lett. , vol.255 , pp. 21-24
    • Grouselle, D.1    Winsky-Sommerer, R.2    David, J.P.3    Delacourte, A.4    Dournaud, P.5    Epelbaum, J.6
  • 25
    • 33746679191 scopus 로고    scopus 로고
    • Activation of spinal GABA receptors attenuates chronic central neuropathic pain after spinal cord injury
    • Y.S. Gwak, H.Y. Tan, T.S. Nam, K.S. Paik, C.E. Hulsebosch, and J.W. Leem Activation of spinal GABA receptors attenuates chronic central neuropathic pain after spinal cord injury J. Neurotrauma 23 2006 1111 1124
    • (2006) J. Neurotrauma , vol.23 , pp. 1111-1124
    • Gwak, Y.S.1    Tan, H.Y.2    Nam, T.S.3    Paik, K.S.4    Hulsebosch, C.E.5    Leem, J.W.6
  • 27
    • 47349084354 scopus 로고    scopus 로고
    • Grafting of striatal precursor cells into hippocampus shortly after status epilepticus restrains chronic temporal lobe epilepsy
    • B. Hattiangady, M.S. Rao, and A.K. Shetty Grafting of striatal precursor cells into hippocampus shortly after status epilepticus restrains chronic temporal lobe epilepsy Exp. Neurol. 212 2008 468 481
    • (2008) Exp. Neurol. , vol.212 , pp. 468-481
    • Hattiangady, B.1    Rao, M.S.2    Shetty, A.K.3
  • 28
    • 84953905170 scopus 로고    scopus 로고
    • Survival, differentiation and functional effects of human iPSC-derived MGE progenitor cells in a model of temporal lobe epilepsy
    • B. Hattiangady, Y. Liu, B. Shuai, L. Yao, X. Rao, S.-C. Zhang, and A.K. Shetty Survival, differentiation and functional effects of human iPSC-derived MGE progenitor cells in a model of temporal lobe epilepsy Soc. Neurosc. Abstr. 414 2013 18/C19
    • (2013) Soc. Neurosc. Abstr. , vol.414 , pp. 18/C19
    • Hattiangady, B.1    Liu, Y.2    Shuai, B.3    Yao, L.4    Rao, X.5    Zhang, S.-C.6    Shetty, A.K.7
  • 29
    • 84863337843 scopus 로고    scopus 로고
    • Alzheimer mechanisms and therapeutic strategies
    • Y. Huang, and L. Mucke Alzheimer mechanisms and therapeutic strategies Cell 148 2012 1204 1222
    • (2012) Cell , vol.148 , pp. 1204-1222
    • Huang, Y.1    Mucke, L.2
  • 30
    • 84878531145 scopus 로고    scopus 로고
    • GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior
    • R.F. Hunt, K.M. Girskis, J.L. Rubenstein, A. Alvarez-Buylla, and S.C. Baraban GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior Nat. Neurosci. 16 2013 692 697
    • (2013) Nat. Neurosci. , vol.16 , pp. 692-697
    • Hunt, R.F.1    Girskis, K.M.2    Rubenstein, J.L.3    Alvarez-Buylla, A.4    Baraban, S.C.5
  • 31
    • 80054838537 scopus 로고    scopus 로고
    • How inhibition shapes cortical activity
    • J.S. Isaacson, and M. Scanziani How inhibition shapes cortical activity Neuron 72 2011 231 243
    • (2011) Neuron , vol.72 , pp. 231-243
    • Isaacson, J.S.1    Scanziani, M.2
  • 32
    • 84857501147 scopus 로고    scopus 로고
    • Intraspinal transplantation of GABAergic neural progenitors attenuates neuropathic pain in rats: A pharmacologic and neurophysiological evaluation
    • S. Jergova, I.D. Hentall, S. Gajavelli, M.S. Varghese, and J. Sagen Intraspinal transplantation of GABAergic neural progenitors attenuates neuropathic pain in rats: a pharmacologic and neurophysiological evaluation Exp. Neurol. 234 2012 39 49
    • (2012) Exp. Neurol. , vol.234 , pp. 39-49
    • Jergova, S.1    Hentall, I.D.2    Gajavelli, S.3    Varghese, M.S.4    Sagen, J.5
  • 33
    • 76749092618 scopus 로고    scopus 로고
    • Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment
    • M.T. Koh, R.P. Haberman, S. Foti, T.J. McCown, and M. Gallagher Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment Neuropsychopharmacology 35 2010 1016 1025
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1016-1025
    • Koh, M.T.1    Haberman, R.P.2    Foti, S.3    McCown, T.J.4    Gallagher, M.5
  • 34
    • 80052432709 scopus 로고    scopus 로고
    • Differential susceptibility of interneurons expressing neuropeptide y or parvalbumin in the aged hippocampus to acute seizure activity
    • R. Kuruba, B. Hattiangady, V.K. Parihar, B. Shuai, and A.K. Shetty Differential susceptibility of interneurons expressing neuropeptide Y or parvalbumin in the aged hippocampus to acute seizure activity PLoS One 6 2011 e24493
    • (2011) PLoS One , vol.6 , pp. e24493
    • Kuruba, R.1    Hattiangady, B.2    Parihar, V.K.3    Shuai, B.4    Shetty, A.K.5
  • 35
    • 0032987267 scopus 로고    scopus 로고
    • Increased dopamine transmission in schizophrenia: Relationship to illness phases
    • M. Laruelle, A. Abi-Dargham, R. Gil, L. Kegeles, and R. Innis Increased dopamine transmission in schizophrenia: relationship to illness phases Biol. Psychiatry 46 1999 56 72
    • (1999) Biol. Psychiatry , vol.46 , pp. 56-72
    • Laruelle, M.1    Abi-Dargham, A.2    Gil, R.3    Kegeles, L.4    Innis, R.5
  • 36
    • 84871742808 scopus 로고    scopus 로고
    • Apolipoprotein E4 causes age- and sex-dependent impairments of hilar GABAergic interneurons and learning and memory deficits in mice
    • L. Leung, Y. Andrews-Zwilling, S.Y. Yoon, S. Jain, K. Ring, J. Dai, M.M. Wang, L. Tong, D. Walker, and Y. Huang Apolipoprotein E4 causes age- and sex-dependent impairments of hilar GABAergic interneurons and learning and memory deficits in mice PLoS One 7 2012 e53569
    • (2012) PLoS One , vol.7 , pp. e53569
    • Leung, L.1    Andrews-Zwilling, Y.2    Yoon, S.Y.3    Jain, S.4    Ring, K.5    Dai, J.6    Wang, M.M.7    Tong, L.8    Walker, D.9    Huang, Y.10
  • 38
    • 84883387241 scopus 로고    scopus 로고
    • Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells
    • Y. Liu, H. Liu, C. Sauvey, L. Yao, E.D. Zarnowska, and S.C. Zhang Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells Nat. Protoc. 8 2013 1670 1679
    • (2013) Nat. Protoc. , vol.8 , pp. 1670-1679
    • Liu, Y.1    Liu, H.2    Sauvey, C.3    Yao, L.4    Zarnowska, E.D.5    Zhang, S.C.6
  • 39
    • 84877342649 scopus 로고    scopus 로고
    • Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits
    • Y. Liu, J.P. Weick, H. Liu, R. Krencik, X. Zhang, L. Ma, G.M. Zhou, M. Ayala, and S.C. Zhang Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits Nat. Biotechnol. 31 2013 440 447
    • (2013) Nat. Biotechnol. , vol.31 , pp. 440-447
    • Liu, Y.1    Weick, J.P.2    Liu, H.3    Krencik, R.4    Zhang, X.5    Ma, L.6    Zhou, G.M.7    Ayala, M.8    Zhang, S.C.9
  • 40
    • 35448996395 scopus 로고    scopus 로고
    • Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia
    • D.J. Lodge, and A.A. Grace Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia J. Neurosci. 27 2007 11424 11430
    • (2007) J. Neurosci. , vol.27 , pp. 11424-11430
    • Lodge, D.J.1    Grace, A.A.2
  • 41
    • 61449095547 scopus 로고    scopus 로고
    • A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia
    • D.J. Lodge, M.M. Behrens, and A.A. Grace A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia J. Neurosci. 29 2009 2344 2354
    • (2009) J. Neurosci. , vol.29 , pp. 2344-2354
    • Lodge, D.J.1    Behrens, M.M.2    Grace, A.A.3
  • 42
    • 80052035263 scopus 로고    scopus 로고
    • Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia
    • D.J. Lodge, and A.A. Grace Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia Trends Pharmacol. Sci. 32 2011 507 513
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 507-513
    • Lodge, D.J.1    Grace, A.A.2
  • 43
    • 77950688386 scopus 로고    scopus 로고
    • Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells
    • A.M. Maroof, K. Brown, S.H. Shi, L. Studer, and S.A. Anderson Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells J. Neurosci. 30 2010 4667 4675
    • (2010) J. Neurosci. , vol.30 , pp. 4667-4675
    • Maroof, A.M.1    Brown, K.2    Shi, S.H.3    Studer, L.4    Anderson, S.A.5
  • 46
    • 0035189584 scopus 로고    scopus 로고
    • Probing the human hippocampus using rCBF: Contrasts in schizophrenia
    • D.R. Medoff, H.H. Holcomb, A.C. Lahti, and C.A. Tamminga Probing the human hippocampus using rCBF: contrasts in schizophrenia Hippocampus 11 2001 543 550
    • (2001) Hippocampus , vol.11 , pp. 543-550
    • Medoff, D.R.1    Holcomb, H.H.2    Lahti, A.C.3    Tamminga, C.A.4
  • 47
    • 0036703985 scopus 로고    scopus 로고
    • Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord
    • K.A. Moore, T. Kohno, L.A. Karchewski, J. Scholz, H. Baba, and C.J. Woolf Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord J. Neurosci. 22 2002 6724 6731
    • (2002) J. Neurosci. , vol.22 , pp. 6724-6731
    • Moore, K.A.1    Kohno, T.2    Karchewski, L.A.3    Scholz, J.4    Baba, H.5    Woolf, C.J.6
  • 49
    • 77954243474 scopus 로고    scopus 로고
    • Selective potentiation of gabapentin-mediated antinociception in the rat formalin test by the nicotinic acetylcholine receptor agonist ABT-594
    • G. Munro, H. Dyhr, and M. Grunnet Selective potentiation of gabapentin-mediated antinociception in the rat formalin test by the nicotinic acetylcholine receptor agonist ABT-594 Neuropharmacology 59 2010 208 217
    • (2010) Neuropharmacology , vol.59 , pp. 208-217
    • Munro, G.1    Dyhr, H.2    Grunnet, M.3
  • 51
    • 72949111183 scopus 로고    scopus 로고
    • Dopaminergic transplantation for Parkinsons disease: Current status and future prospects
    • C.W. Olanow, J.H. Kordower, A.E. Lang, and J.A. Obeso Dopaminergic transplantation for Parkinsons disease: current status and future prospects Ann. Neurol. 66 2009 591 596
    • (2009) Ann. Neurol. , vol.66 , pp. 591-596
    • Olanow, C.W.1    Kordower, J.H.2    Lang, A.E.3    Obeso, J.A.4
  • 52
    • 84888302817 scopus 로고    scopus 로고
    • Hippocampal interneuron transplants reverse aberrant dopamine system function and behavior in a rodent model of schizophrenia
    • S.M. Perez, and D.J. Lodge Hippocampal interneuron transplants reverse aberrant dopamine system function and behavior in a rodent model of schizophrenia Mol. Psychiatry 18 2013 1193 1198
    • (2013) Mol. Psychiatry , vol.18 , pp. 1193-1198
    • Perez, S.M.1    Lodge, D.J.2
  • 53
    • 84878866859 scopus 로고    scopus 로고
    • Hippocampal deep brain stimulation reverses physiological and behavioral deficits in a rodent model of schizophrenia
    • S.M. Perez, A. Shah, A. Asher, and D.J. Lodge Hippocampal deep brain stimulation reverses physiological and behavioral deficits in a rodent model of schizophrenia Int. J. Neuropsychopharmacol. 16 2013 1331 1339
    • (2013) Int. J. Neuropsychopharmacol. , vol.16 , pp. 1331-1339
    • Perez, S.M.1    Shah, A.2    Asher, A.3    Lodge, D.J.4
  • 54
    • 0041386058 scopus 로고    scopus 로고
    • Dyskinesias after transplantation in Parkinson's disease
    • P. Piccini Dyskinesias after transplantation in Parkinson's disease Lancet Neurol. 1 2002 472
    • (2002) Lancet Neurol. , vol.1 , pp. 472
    • Piccini, P.1
  • 56
    • 78650038409 scopus 로고    scopus 로고
    • The promise of an interneuron-based cell therapy for epilepsy
    • J.Y. Sebe, and S.C. Baraban The promise of an interneuron-based cell therapy for epilepsy Dev. Neurobiol. 71 2011 107 117
    • (2011) Dev. Neurobiol. , vol.71 , pp. 107-117
    • Sebe, J.Y.1    Baraban, S.C.2
  • 57
    • 0035095970 scopus 로고    scopus 로고
    • Differences between GABA levels in Alzheimers disease and Down syndrome with Alzheimer-like neuropathology
    • R. Seidl, N. Cairns, N. Singewald, S.T. Kaehler, and G. Lubec Differences between GABA levels in Alzheimers disease and Down syndrome with Alzheimer-like neuropathology Naunyn Schmiedebergs Arch. Pharmacol. 363 2001 139 145
    • (2001) Naunyn Schmiedebergs Arch. Pharmacol. , vol.363 , pp. 139-145
    • Seidl, R.1    Cairns, N.2    Singewald, N.3    Kaehler, S.T.4    Lubec, G.5
  • 58
    • 84879715242 scopus 로고    scopus 로고
    • A loss of hippocampal perineuronal nets produces deficits in dopamine system function: Relevance to the positive symptoms of schizophrenia. Transl
    • A. Shah, and D.J. Lodge A loss of hippocampal perineuronal nets produces deficits in dopamine system function: relevance to the positive symptoms of schizophrenia. Transl Psychiatry 3 2013 e215
    • (2013) Psychiatry , vol.3 , pp. e215
    • Shah, A.1    Lodge, D.J.2
  • 59
    • 0032482182 scopus 로고    scopus 로고
    • Hippocampal interneurons expressing glutamic acid decarboxylase and calcium-binding proteins decrease with aging in Fischer 344 rats
    • A.K. Shetty, and D.A. Turner Hippocampal interneurons expressing glutamic acid decarboxylase and calcium-binding proteins decrease with aging in Fischer 344 rats J. Comp. Neurol. 394 1998 252 269
    • (1998) J. Comp. Neurol. , vol.394 , pp. 252-269
    • Shetty, A.K.1    Turner, D.A.2
  • 60
    • 0034555122 scopus 로고    scopus 로고
    • Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in a rat model of temporal lobe epilepsy
    • A.K. Shetty, and D.A. Turner Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in a rat model of temporal lobe epilepsy J. Neurosci. 20 2000 8788 8801
    • (2000) J. Neurosci. , vol.20 , pp. 8788-8801
    • Shetty, A.K.1    Turner, D.A.2
  • 61
    • 72949102234 scopus 로고    scopus 로고
    • Vulnerability of hippocampal GABA-ergic interneurons to kainate-induced excitotoxic injury during old age
    • A.K. Shetty, B. Hattiangady, and M.S. Rao Vulnerability of hippocampal GABA-ergic interneurons to kainate-induced excitotoxic injury during old age J. Cell Mol. Med. 13 2009 2408 2423
    • (2009) J. Cell Mol. Med. , vol.13 , pp. 2408-2423
    • Shetty, A.K.1    Hattiangady, B.2    Rao, M.S.3
  • 62
    • 80955125660 scopus 로고    scopus 로고
    • Progress in cell grafting therapy for temporal lobe epilepsy
    • A.K. Shetty Progress in cell grafting therapy for temporal lobe epilepsy Neurotherapeutics 8 2011 721 735
    • (2011) Neurotherapeutics , vol.8 , pp. 721-735
    • Shetty, A.K.1
  • 63
    • 84910660356 scopus 로고    scopus 로고
    • Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: Can early neural stem cell grafting intervention provide protection?
    • A.K. Shetty Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: can early neural stem cell grafting intervention provide protection? Epilepsy Behav. 38 2014 117 124
    • (2014) Epilepsy Behav. , vol.38 , pp. 117-124
    • Shetty, A.K.1
  • 66
    • 84883004035 scopus 로고    scopus 로고
    • Hilar interneuron vulnerability distinguishes aged rats with memory impairment
    • A.M. Spiegel, M.T. Koh, N.M. Vogt, P.R. Rapp, and M. Gallagher Hilar interneuron vulnerability distinguishes aged rats with memory impairment J. Comp. Neurol. 521 2013 3508 3523
    • (2013) J. Comp. Neurol. , vol.521 , pp. 3508-3523
    • Spiegel, A.M.1    Koh, M.T.2    Vogt, N.M.3    Rapp, P.R.4    Gallagher, M.5
  • 67
    • 1842509983 scopus 로고    scopus 로고
    • Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration
    • D.P. Stanley, and A.K. Shetty Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration J. Neurochem. 89 2004 204 216
    • (2004) J. Neurochem. , vol.89 , pp. 204-216
    • Stanley, D.P.1    Shetty, A.K.2
  • 68
    • 80053653809 scopus 로고    scopus 로고
    • GABAergic precursor transplantation into the prefrontal cortex prevents phencyclidine-induced cognitive deficits
    • D.H. Tanaka, K. Toriumi, K. Kubo, T. Nabeshima, and K. Nakajima GABAergic precursor transplantation into the prefrontal cortex prevents phencyclidine-induced cognitive deficits J. Neurosci. 31 2011 14116 14125
    • (2011) J. Neurosci. , vol.31 , pp. 14116-14125
    • Tanaka, D.H.1    Toriumi, K.2    Kubo, K.3    Nabeshima, T.4    Nakajima, K.5
  • 70
    • 84894495428 scopus 로고    scopus 로고
    • GABAergic interneuron transplants to study development and treat disease
    • J.A. Tyson, and S.A. Anderson GABAergic interneuron transplants to study development and treat disease Trends Neurosci. 37 2014 169 177
    • (2014) Trends Neurosci. , vol.37 , pp. 169-177
    • Tyson, J.A.1    Anderson, S.A.2
  • 72
  • 73
    • 0034773221 scopus 로고    scopus 로고
    • In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain
    • H. Wichterle, D.H. Turnbull, S. Nery, G. Fishell, and A. Alvarez-Buylla In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain Development 128 2001 3759 3771
    • (2001) Development , vol.128 , pp. 3759-3771
    • Wichterle, H.1    Turnbull, D.H.2    Nery, S.3    Fishell, G.4    Alvarez-Buylla, A.5
  • 75
    • 77952422876 scopus 로고    scopus 로고
    • High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic mild cognitive impairment
    • M.A. Yassa, S.M. Stark, A. Bakker, M.S. Albert, M. Gallagher, and C.E. Stark High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic mild cognitive impairment Neuro Image 51 2010 1242 1252
    • (2010) Neuro Image , vol.51 , pp. 1242-1252
    • Yassa, M.A.1    Stark, S.M.2    Bakker, A.3    Albert, M.S.4    Gallagher, M.5    Stark, C.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.