메뉴 건너뛰기




Volumn 8, Issue 1, 1999, Pages 87-101

Transplants of neuronal cells bioengineered to synthesize GABA alleviate chronic neuropathic pain

Author keywords

Chronic constriction injury; GABA; Neural cell lines; Transplantation

Indexed keywords

4 AMINOBUTYRIC ACID; COMPLEMENTARY DNA; GLUTAMATE DECARBOXYLASE; VIRUS LARGE T ANTIGEN;

EID: 0032867326     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1177/096368979900800102     Document Type: Article
Times cited : (92)

References (82)
  • 1
    • 0020072721 scopus 로고
    • The cytoarchitecture of GABAergic neurons in rat spinal cord
    • Barber, R. P.; Vaughn, J. E.; Roberts, E. The cytoarchitecture of GABAergic neurons in rat spinal cord. Brain Res. 238:305-328; 1982.
    • (1982) Brain Res. , vol.238 , pp. 305-328
    • Barber, R.P.1    Vaughn, J.E.2    Roberts, E.3
  • 2
    • 0023895875 scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • Bennett, G. J.; Xie, Y.-K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33:87-107; 1988.
    • (1988) Pain , vol.33 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.-K.2
  • 3
    • 0025231691 scopus 로고
    • Neural transplantation using temperature sensitive immortalized neural cells: A preliminary report
    • Bredesen, D. E.; Hisanaga, M. D.; Sharp, F. A. Neural transplantation using temperature sensitive immortalized neural cells: A preliminary report. Ann. Neurol. 27:205-207: 1990.
    • (1990) Ann. Neurol. , vol.27 , pp. 205-207
    • Bredesen, D.E.1    Hisanaga, M.D.2    Sharp, F.A.3
  • 4
    • 0024340539 scopus 로고
    • Survival and growth of hippocampal neurons in defined medium at low density: Advantages of a sandwich culture technique or low oxygen
    • Brewer, G. J.; Cotman, C. W. Survival and growth of hippocampal neurons in defined medium at low density: Advantages of a sandwich culture technique or low oxygen. Brain Res. 494:65-74; 1989.
    • (1989) Brain Res. , vol.494 , pp. 65-74
    • Brewer, G.J.1    Cotman, C.W.2
  • 5
    • 0344621330 scopus 로고
    • Nonopioid analgesics
    • Kuhar, M.: Pasternak, G., eds. New York: Raven Press
    • Brune, K. I.; Lanz, R. Nonopioid analgesics. In: Kuhar, M.: Pasternak, G., eds. Nonopioid analgesics. New York: Raven Press; 1984:149-173.
    • (1984) Nonopioid Analgesics , pp. 149-173
    • Brune, K.I.1    Lanz, R.2
  • 6
    • 0000763280 scopus 로고
    • Present status of tricylic antidepressants in chronic pain therapy
    • Benedetti, C.; Chapman, C. R.; Moricca, G., eds. New York: Raven Press
    • Butler, S. Present status of tricylic antidepressants in chronic pain therapy. In: Benedetti, C.; Chapman, C. R.; Moricca, G., eds. Present status of tricylic antidepressants in chronic pain therapy. New York: Raven Press; 1984: 173-197.
    • (1984) Present Status of Tricylic Antidepressants in Chronic Pain Therapy , pp. 173-197
    • Butler, S.1
  • 7
    • 0027242053 scopus 로고
    • GABA decreases in the spinal cord dorsal horn after peripheral neurectomy
    • Castro-Lopes, J. M.; Tavares, I.; Coimbra, A. GABA decreases in the spinal cord dorsal horn after peripheral neurectomy. Brain Res. 620:287-291; 1993.
    • (1993) Brain Res. , vol.620 , pp. 287-291
    • Castro-Lopes, J.M.1    Tavares, I.2    Coimbra, A.3
  • 9
    • 0028795139 scopus 로고
    • The role of the basal ganglia in nociception and pain
    • Chidler, E. H.; Dong, W. K. The role of the basal ganglia in nociception and pain. Pain 60:3-38; 1995.
    • (1995) Pain , vol.60 , pp. 3-38
    • Chidler, E.H.1    Dong, W.K.2
  • 10
    • 0011349597 scopus 로고
    • Temporal development of mechanical allodynia and thermal hyperalgesia in chronic central pain following spinal cord injury
    • Christensen, M. D.; Pickelman, J.; Ziainia, M.; Hulsebosch, C. E. Temporal development of mechanical allodynia and thermal hyperalgesia in chronic central pain following spinal cord injury. Am. Pain Soc. Absr. 95811; 1995.
    • (1995) Am. Pain Soc. Absr. 95811
    • Christensen, M.D.1    Pickelman, J.2    Ziainia, M.3    Hulsebosch, C.E.4
  • 11
    • 0030864230 scopus 로고    scopus 로고
    • Spinal cord stimulation attenuates augmented dorsal horn release of excitatory amino acids in mononeuropathy via a GABAergic mechanism
    • Cui, J.-G.; O'Connor, W. T.; Ungerstedt, U.; Linderoth, B.; Meyerson, B. A. Spinal cord stimulation attenuates augmented dorsal horn release of excitatory amino acids in mononeuropathy via a GABAergic mechanism. Pain 73:87-95; 1997.
    • (1997) Pain , vol.73 , pp. 87-95
    • Cui, J.-G.1    O'Connor, W.T.2    Ungerstedt, U.3    Linderoth, B.4    Meyerson, B.A.5
  • 12
    • 0023469731 scopus 로고
    • GABA-ergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat
    • Depaulis, A.; Morgan, M. M.; Liebeskind, J. C. GABA-ergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat. Brain Res. 436:223-228; 1987.
    • (1987) Brain Res. , vol.436 , pp. 223-228
    • Depaulis, A.1    Morgan, M.M.2    Liebeskind, J.C.3
  • 13
    • 0030974434 scopus 로고    scopus 로고
    • The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cord
    • Dickenson, A. H.; Chapman, V.; Green, G. M. The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cord. Gen. Pharmacol. 28:633-638; 1997.
    • (1997) Gen. Pharmacol. , vol.28 , pp. 633-638
    • Dickenson, A.H.1    Chapman, V.2    Green, G.M.3
  • 14
    • 0030791867 scopus 로고    scopus 로고
    • Lumbar transplants of immortalized serotonergic neurons alleviates chronic neuropathic pain
    • Eaton, M. J.; Dancausse, H. R.; Santiago, D. I.; Whittemore. S. R. Lumbar transplants of immortalized serotonergic neurons alleviates chronic neuropathic pain. Pain 72: 59-69; 1997.
    • (1997) Pain , vol.72 , pp. 59-69
    • Eaton, M.J.1    Dancausse, H.R.2    Santiago, D.I.3    Whittemore, S.R.4
  • 15
    • 0032448274 scopus 로고    scopus 로고
    • Changes in GAD and GABA immunoreactivity in the spinal dorsal horn after peripheral nerve injury and promotion of recovery by lumbar transplant of immortalized serotonergic neurons
    • in press
    • Eaton, M. J.; Plunkett, J. A.; Martinez, M. A.; Karmally, S.; Montanez, K.; Rabade, J. Changes in GAD and GABA immunoreactivity in the spinal dorsal horn after peripheral nerve injury and promotion of recovery by lumbar transplant of immortalized serotonergic neurons. J. Chem. Neuroanat. (in press).
    • J. Chem. Neuroanat.
    • Eaton, M.J.1    Plunkett, J.A.2    Martinez, M.A.3    Karmally, S.4    Montanez, K.5    Rabade, J.6
  • 16
    • 0029119322 scopus 로고
    • Developmental regulation of early serotonergic neuronal differentiation: The role of brain-derived neurotrophic factor and membrane depolarization
    • Eaton, M. J.; Staley, J. K.: Globus, M. Y. T.; Whittemore, S. R. Developmental regulation of early serotonergic neuronal differentiation: The role of brain-derived neurotrophic factor and membrane depolarization. Dev. Biol. 170:169-182; 1995.
    • (1995) Dev. Biol. , vol.170 , pp. 169-182
    • Eaton, M.J.1    Staley, J.K.2    Globus, M.Y.T.3    Whittemore, S.R.4
  • 17
    • 0030222250 scopus 로고    scopus 로고
    • Autocrine BDNF secretion enhances the survival and serotonergic differentiation of raphe neuronal precursor cells grafted into the adult rat CNS
    • Eaton, M. J.; Whittemore, S. R. Autocrine BDNF secretion enhances the survival and serotonergic differentiation of raphe neuronal precursor cells grafted into the adult rat CNS. Exp. Neurol. 140:105-114; 1996.
    • (1996) Exp. Neurol. , vol.140 , pp. 105-114
    • Eaton, M.J.1    Whittemore, S.R.2
  • 18
    • 0024057953 scopus 로고
    • Immortalization of precursor cells from the mammalian CNS
    • Frederiksen, K.; Jat, P. S.; Valtz, N.; Levy, D.; McKay, R. Immortalization of precursor cells from the mammalian CNS. Neuron 1:439-448; 1988.
    • (1988) Neuron , vol.1 , pp. 439-448
    • Frederiksen, K.1    Jat, P.S.2    Valtz, N.3    Levy, D.4    McKay, R.5
  • 19
    • 0023906672 scopus 로고
    • Proliferation and differentiation of rat neuroepithelial precursor cells in vivo
    • Frederiksen, K.; McKay, R. D. G. Proliferation and differentiation of rat neuroepithelial precursor cells in vivo. J. Neurosci. 8:1144-1151; 1988.
    • (1988) J. Neurosci. , vol.8 , pp. 1144-1151
    • Frederiksen, K.1    McKay, R.D.G.2
  • 20
    • 0028572528 scopus 로고
    • Baclofen as an adjuvant analgesic
    • Fromm, G. H. Baclofen as an adjuvant analgesic. J. Pain Symp. Mgmt. 9:500-509; 1994.
    • (1994) J. Pain Symp. Mgmt. , vol.9 , pp. 500-509
    • Fromm, G.H.1
  • 21
    • 0021954789 scopus 로고
    • Distribution, ontogeny, and projections of cholecystokinin-8, vasoactive intestinal polypeptide and gamma-aminobutyrate-containing neuron systems in the rat spinal cord: An immunohistochemical analysis
    • Fuji, K.; Senba, E.; Fuji, S.; Nomura, I.; Wu, J.-Y. Distribution, ontogeny, and projections of cholecystokinin-8, vasoactive intestinal polypeptide and gamma-aminobutyrate-containing neuron systems in the rat spinal cord: An immunohistochemical analysis. Neuroscience 14:881-894; 1985.
    • (1985) Neuroscience , vol.14 , pp. 881-894
    • Fuji, K.1    Senba, E.2    Fuji, S.3    Nomura, I.4    Wu, J.-Y.5
  • 23
    • 0025752482 scopus 로고
    • Allodynia-like effects in rat after ischaemic spinal cord injury photochemically induced by laser irradiation
    • Hao, J.-X.; Xu, X.-J.; Aldskogius, H.; Seiger, A.; Wiesenfeld-Hallin, Z. Allodynia-like effects in rat after ischaemic spinal cord injury photochemically induced by laser irradiation. Pain 45:175-185; 1991.
    • (1991) Pain , vol.45 , pp. 175-185
    • Hao, J.-X.1    Xu, X.-J.2    Aldskogius, H.3    Seiger, A.4    Wiesenfeld-Hallin, Z.5
  • 24
    • 0026501374 scopus 로고
    • Chronic pain related syndrome in rats after ischemic spinal cord lesion: A possible animal model for pain in patients with spinal cord injury
    • Hao, J.-X.; Xu, X.-J.; Aldskogius, H.; Seiger, A.; Wiesenfeld-Hallin, Z. Chronic pain related syndrome in rats after ischemic spinal cord lesion: A possible animal model for pain in patients with spinal cord injury. Pain 48:279-290; 1992.
    • (1992) Pain , vol.48 , pp. 279-290
    • Hao, J.-X.1    Xu, X.-J.2    Aldskogius, H.3    Seiger, A.4    Wiesenfeld-Hallin, Z.5
  • 25
    • 0028173168 scopus 로고
    • Intrathecal gamma-aminobutyric acidB (GABAB) receptor antagonist CGP 35348 induces hypersensitivity to mechanical stimuli in the rat
    • Hao, J. X.; Xu, X. J.; Wiesenfeld-Hallin, Z. Intrathecal gamma-aminobutyric acidB (GABAB) receptor antagonist CGP 35348 induces hypersensitivity to mechanical stimuli in the rat. Neurosci. Lett. 182:299-302; 1994.
    • (1994) Neurosci. Lett. , vol.182 , pp. 299-302
    • Hao, J.X.1    Xu, X.J.2    Wiesenfeld-Hallin, Z.3
  • 26
    • 0026783882 scopus 로고
    • Baclofen reverses the hypersensitivity of dorsal horn wide dynamic range neurons to mechanical stimulation after transient spinal cord ischemia; implications for a tonic GABAergic inhibitory control of myelinated fiber input
    • Hao, J. X.; Xu, X. J.; Yu, Y. X.; Seiger, A.; Wiesenfeld-Hallin, Z. Baclofen reverses the hypersensitivity of dorsal horn wide dynamic range neurons to mechanical stimulation after transient spinal cord ischemia; implications for a tonic GABAergic inhibitory control of myelinated fiber input. J. Neurophysiol. 68:392-396; 1992.
    • (1992) J. Neurophysiol. , vol.68 , pp. 392-396
    • Hao, J.X.1    Xu, X.J.2    Yu, Y.X.3    Seiger, A.4    Wiesenfeld-Hallin, Z.5
  • 27
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves, K.; Dubner, R.; Brown, P.; Flores, C.; Joris, J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77-88; 1988.
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, P.3    Flores, C.4    Joris, J.5
  • 28
    • 0027103035 scopus 로고
    • Intrathecal baclofen suppresses central pain in patients with spinal lesions. A pilot study
    • Herman, R. M.; D'Luzansky, S. C.; Ippolitoi, R. Intrathecal baclofen suppresses central pain in patients with spinal lesions. A pilot study. Clin. J. Pain 8:338-345; 1992.
    • (1992) Clin. J. Pain , vol.8 , pp. 338-345
    • Herman, R.M.1    D'Luzansky, S.C.2    Ippolitoi, R.3
  • 29
    • 0029932016 scopus 로고    scopus 로고
    • Evidence of synaptic contacts of nociceptive primary afferent central terminals on GABAergic interneurons in the substantia gelatinosa
    • Hiura, A.; Nasu, F.; Ishizuka, H.; Kuwahara, M.; Ohta, M. Evidence of synaptic contacts of nociceptive primary afferent central terminals on GABAergic interneurons in the substantia gelatinosa. Arch. Histol. Cytol. 59:55-60; 1996.
    • (1996) Arch. Histol. Cytol. , vol.59 , pp. 55-60
    • Hiura, A.1    Nasu, F.2    Ishizuka, H.3    Kuwahara, M.4    Ohta, M.5
  • 30
    • 0344263825 scopus 로고
    • Central sensitization of wide dynamic range neurons in chronic central pain after spinal cord hemisection
    • Hulsebosch, C. E.; Christensen, M. D.; Peng, Y. B.; Willis, W. D. Central sensitization of wide dynamic range neurons in chronic central pain after spinal cord hemisection. Am. Pain Soc. Absr. 95812; 1995.
    • (1995) Am. Pain Soc. Absr. 95812
    • Hulsebosch, C.E.1    Christensen, M.D.2    Peng, Y.B.3    Willis, W.D.4
  • 31
    • 0030580562 scopus 로고    scopus 로고
    • Loss of GABA immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts
    • Ibuki, T.; Hama, A. T.; Wang, X.-T.; Pappas, G. D.; Sagen, J. Loss of GABA immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts. Neuroscience 76: 845-858; 1997.
    • (1997) Neuroscience , vol.76 , pp. 845-858
    • Ibuki, T.1    Hama, A.T.2    Wang, X.-T.3    Pappas, G.D.4    Sagen, J.5
  • 32
    • 0029156558 scopus 로고
    • Effects of iontophoretically applied naloxone, picrotoxin and strychnine on dorsal horn neuron activities treated with high frequency conditioning stimulation in cats
    • Jeong, Y.; Baik, E. J.; Nam, T. S.; Paik, K. S. Effects of iontophoretically applied naloxone, picrotoxin and strychnine on dorsal horn neuron activities treated with high frequency conditioning stimulation in cats. Yonsei Med. J. 36:336-347; 1995.
    • (1995) Yonsei Med. J. , vol.36 , pp. 336-347
    • Jeong, Y.1    Baik, E.J.2    Nam, T.S.3    Paik, K.S.4
  • 33
    • 0022543658 scopus 로고
    • Brain glutamate decarboxylase cloned in lambda gt-11: Fusion protein produces gamma-aminobutyric acid
    • Kaufman, D. L.; McGinnis, J. F.; Krieger, N. R.; Tobin, A. J. Brain glutamate decarboxylase cloned in lambda gt-11: Fusion protein produces gamma-aminobutyric acid. Science 232:1138-1140; 1986.
    • (1986) Science , vol.232 , pp. 1138-1140
    • Kaufman, D.L.1    McGinnis, J.F.2    Krieger, N.R.3    Tobin, A.J.4
  • 34
    • 0023906505 scopus 로고
    • Diminished dorsal root GABA sensitivity following chronic peripheral nerve injury
    • Kingery, W. S.; Fields, R. D.; Kocsis, J. D. Diminished dorsal root GABA sensitivity following chronic peripheral nerve injury. Exp. Neurol. 100:478-490; 1988.
    • (1988) Exp. Neurol. , vol.100 , pp. 478-490
    • Kingery, W.S.1    Fields, R.D.2    Kocsis, J.D.3
  • 35
    • 0021054019 scopus 로고
    • The analgesic effect of the GABA-agonist THIP in patients with chronic pain of malignant origin
    • Kjaer, M.; Nielsen, H. The analgesic effect of the GABA-agonist THIP in patients with chronic pain of malignant origin. Br. J. Clin. Pharmacol. 16:477-485; 1983.
    • (1983) Br. J. Clin. Pharmacol. , vol.16 , pp. 477-485
    • Kjaer, M.1    Nielsen, H.2
  • 37
    • 0027735901 scopus 로고
    • Release of neurotransmitters in the CNS by spinal cord stimulation: Survey of present state of knowledge and recent experimental studies
    • Linderoth, B.; Stiller, C. O.; Gunasekera, L.; O'Connor, W. T.; Frank, J.; Gazelius, B.; Brodin, E. Release of neurotransmitters in the CNS by spinal cord stimulation: Survey of present state of knowledge and recent experimental studies. Stereotact. Funct. Neurosurg. 61:157-170; 1993.
    • (1993) Stereotact. Funct. Neurosurg. , vol.61 , pp. 157-170
    • Linderoth, B.1    Stiller, C.O.2    Gunasekera, L.3    O'Connor, W.T.4    Frank, J.5    Gazelius, B.6    Brodin, E.7
  • 38
    • 0028316369 scopus 로고
    • Gamma-aminobutyric acid is released in the dorsal horn by electrical spinal cord stimulation: An in vivo microdialysis study in the rat
    • Linderoth, B.; Stiller, C. O.; Gunasekera, L.; O'Connor, W. T.; Ungerstedt, U.; Brodin, E. Gamma-aminobutyric acid is released in the dorsal horn by electrical spinal cord stimulation: An in vivo microdialysis study in the rat. Neurosurgery 34:484-488; 1994.
    • (1994) Neurosurgery , vol.34 , pp. 484-488
    • Linderoth, B.1    Stiller, C.O.2    Gunasekera, L.3    O'Connor, W.T.4    Ungerstedt, U.5    Brodin, E.6
  • 39
    • 0027721554 scopus 로고
    • An animal model for the study of brain transmitter release in response to spinal cord stimulation in the awake, freely moving rat: Preliminary results from the periaqueductal grey matter
    • Linderoth, B.; Stiller, C. O.; O'Connor, W. T.; Hammarstrom, G.; Ungerstedt, U.; Brodin, E. An animal model for the study of brain transmitter release in response to spinal cord stimulation in the awake, freely moving rat: Preliminary results from the periaqueductal grey matter. Acta Neurochir. Suppl. 58:156-160; 1993.
    • (1993) Acta Neurochir. Suppl. , vol.58 , pp. 156-160
    • Linderoth, B.1    Stiller, C.O.2    O'Connor, W.T.3    Hammarstrom, G.4    Ungerstedt, U.5    Brodin, E.6
  • 40
    • 0003054562 scopus 로고
    • Peripheral nerve disorders
    • Bonica, J. J., eds. Philadelphia: Lea and Febiger
    • Loeser, J. D. Peripheral nerve disorders. In: Bonica, J. J., eds. Peripheral nerve disorders. Philadelphia: Lea and Febiger; 1990:211-219.
    • (1990) Peripheral Nerve Disorders , pp. 211-219
    • Loeser, J.D.1
  • 41
    • 0016698218 scopus 로고
    • Immunocytochemical localization of glutamate decarboxylase in rat spinal cord
    • McLaughlin, B. J.; Barber, R.; Saito, K.; Roberts, E.; Wu, J. Y. Immunocytochemical localization of glutamate decarboxylase in rat spinal cord. J. Comp. Neurol. 164:305-322; 1975.
    • (1975) J. Comp. Neurol. , vol.164 , pp. 305-322
    • McLaughlin, B.J.1    Barber, R.2    Saito, K.3    Roberts, E.4    Wu, J.Y.5
  • 42
    • 0038357025 scopus 로고
    • Psychotropic drugs
    • Wall, P. D.; Melzack, R. M., eds. Edinburgh: Churchhill Livingston
    • Monks, R.; Mersky, H. Psychotropic drugs. In: Wall, P. D.; Melzack, R. M., eds. Psychotropic drugs. Edinburgh: Churchhill Livingston; 1984:526-537.
    • (1984) Psychotropic Drugs , pp. 526-537
    • Monks, R.1    Mersky, H.2
  • 43
    • 0040269544 scopus 로고    scopus 로고
    • Descending modulation and nociceptive transmission
    • Morgan, M. M. Descending modulation and nociceptive transmission. Pain Forum 5:23-27; 1996.
    • (1996) Pain Forum , vol.5 , pp. 23-27
    • Morgan, M.M.1
  • 44
    • 0021028632 scopus 로고
    • Zinc-aldehyde fixation for light-microscopic immunocytochemistry of nervous tissues
    • Mugnaini, E.; Dahl, A.-L. Zinc-aldehyde fixation for light-microscopic immunocytochemistry of nervous tissues. J. Histochem. Cytochem. 31:1435-1438; 1983.
    • (1983) J. Histochem. Cytochem. , vol.31 , pp. 1435-1438
    • Mugnaini, E.1    Dahl, A.-L.2
  • 45
    • 0018559937 scopus 로고
    • Correlation of changes in the GABA-ergic system with the development of spasticity in paraplegic cats
    • Naftchi, N. E.; Schlosser, W.; Horst, W. D. Correlation of changes in the GABA-ergic system with the development of spasticity in paraplegic cats. Adv. Exp. Med. Biol. 123: 431-450; 1979.
    • (1979) Adv. Exp. Med. Biol. , vol.123 , pp. 431-450
    • Naftchi, N.E.1    Schlosser, W.2    Horst, W.D.3
  • 46
    • 0019789091 scopus 로고
    • Immunocytochemical localization of glutamate decarboxylase in rat cerebellum with a new antiserum
    • Oertel, W. H.; Schmechel, D. E.; Mugnaini, E.; Tappaz, M. L.; Kopin, I. J. Immunocytochemical localization of glutamate decarboxylase in rat cerebellum with a new antiserum. Neuroscience 6:225-235; 1981.
    • (1981) Neuroscience , vol.6 , pp. 225-235
    • Oertel, W.H.1    Schmechel, D.E.2    Mugnaini, E.3    Tappaz, M.L.4    Kopin, I.J.5
  • 47
    • 0027297937 scopus 로고
    • In vitro labeling strategies for identifying primary neural tissue and a neuronal cell line after transplantation in the CNS
    • Onifer, S. M.; White, L. A.; Whittemore, S. R.; Holets, V. R. In vitro labeling strategies for identifying primary neural tissue and a neuronal cell line after transplantation in the CNS. Cell Transplant. 2:131-149; 1993.
    • (1993) Cell Transplant. , vol.2 , pp. 131-149
    • Onifer, S.M.1    White, L.A.2    Whittemore, S.R.3    Holets, V.R.4
  • 48
    • 0028604391 scopus 로고
    • Effect of amitriptyline on the analgesia induced by adrenal medullary tissue transplanted in the rat spinal subarachnoid space as measured by an experimental model of acute pain
    • Ortega-Alvaro, A.; Gibert-Rahola, J.; Chover, A. J.; Tejedor-Real, P.; Casas, J.; Mico, J. A. Effect of amitriptyline on the analgesia induced by adrenal medullary tissue transplanted in the rat spinal subarachnoid space as measured by an experimental model of acute pain. Exp. Neurol. 130:9-14; 1994.
    • (1994) Exp. Neurol. , vol.130 , pp. 9-14
    • Ortega-Alvaro, A.1    Gibert-Rahola, J.2    Chover, A.J.3    Tejedor-Real, P.4    Casas, J.5    Mico, J.A.6
  • 50
    • 84960959252 scopus 로고
    • A method for measurement of analgesic activity on inflamed tissue
    • Randall, L.; Selitto, J. A method for measurement of analgesic activity on inflamed tissue. Arch. Int. Pharmacodyn. 4:409-419; 1957.
    • (1957) Arch. Int. Pharmacodyn. , vol.4 , pp. 409-419
    • Randall, L.1    Selitto, J.2
  • 51
    • 0021178771 scopus 로고
    • Towards an improved serum-free, chemically defined medium for long-term culturing of cerebral cortex tissue
    • Romijn, H. J.; Huizen, F. V.; Walters, P. S. Towards an improved serum-free, chemically defined medium for long-term culturing of cerebral cortex tissue. Neurosci. Behav. Rev. 8:301-334; 1984.
    • (1984) Neurosci. Behav. Rev. , vol.8 , pp. 301-334
    • Romijn, H.J.1    Huizen, F.V.2    Walters, P.S.3
  • 52
    • 0026284774 scopus 로고
    • Study of the analgesic effects of the implant of adrenal medullary into the subarachnoid space in rats
    • Ruz-Franzi, J. I.; Gonzalez-Darder, J. M. Study of the analgesic effects of the implant of adrenal medullary into the subarachnoid space in rats. Acta Neurochir. Suppl. 52: 39-41; 1991.
    • (1991) Acta Neurochir. Suppl. , vol.52 , pp. 39-41
    • Ruz-Franzi, J.I.1    Gonzalez-Darder, J.M.2
  • 53
    • 0025959403 scopus 로고
    • Adrenal medullary transplants increase spinal cord cerebral spinal fluid catecholamine levels and reduce pain sensitivity
    • Sagen, J.; Kemmler, J. E.; Wang, H. Adrenal medullary transplants increase spinal cord cerebral spinal fluid catecholamine levels and reduce pain sensitivity. J. Neurochem. 56:623-627; 1991.
    • (1991) J. Neurochem. , vol.56 , pp. 623-627
    • Sagen, J.1    Kemmler, J.E.2    Wang, H.3
  • 54
    • 0022449547 scopus 로고
    • Adrenal medullary tissue transplants in the rat spinal cord reduce pain sensitivity
    • Sagen, J.; Pappas, G. D.; Perlow, M. J. Adrenal medullary tissue transplants in the rat spinal cord reduce pain sensitivity. Brain Res. 384:189-194; 1986.
    • (1986) Brain Res. , vol.384 , pp. 189-194
    • Sagen, J.1    Pappas, G.D.2    Perlow, M.J.3
  • 55
    • 0023267855 scopus 로고
    • Alterations in nociception following adrenal medullary transplants into the periaqueductal gray
    • Sagen, J.; Pappas, G. D.; Perlow, M. J. Alterations in nociception following adrenal medullary transplants into the periaqueductal gray. Exp. Brain Res. 67:373-379; 1987.
    • (1987) Exp. Brain Res. , vol.67 , pp. 373-379
    • Sagen, J.1    Pappas, G.D.2    Perlow, M.J.3
  • 56
    • 0025372204 scopus 로고
    • Adrenal medullary implants in the rat spinal cord reduce nociception in a chronic pain model
    • Sagen, J.; Wang, H.; Pappas, G. D. Adrenal medullary implants in the rat spinal cord reduce nociception in a chronic pain model. Pain 42:69-79; 1990.
    • (1990) Pain , vol.42 , pp. 69-79
    • Sagen, J.1    Wang, H.2    Pappas, G.D.3
  • 57
    • 0027288001 scopus 로고
    • Transplants of immunologically isolated xenogenic chromaffin cells provide a long-term source of pain-reducing neuroactive substances
    • Sagen, J.; Wang, H.; Tresco, P. A.; Aebischer, P. Transplants of immunologically isolated xenogenic chromaffin cells provide a long-term source of pain-reducing neuroactive substances. J. Neurosci. 13:2415-2423; 1993.
    • (1993) J. Neurosci. , vol.13 , pp. 2415-2423
    • Sagen, J.1    Wang, H.2    Tresco, P.A.3    Aebischer, P.4
  • 58
    • 0028959349 scopus 로고
    • Cell therapy with encapsulated xenogenic tumor cells secreting B-endorphin for treatment of peripheral pain
    • Saitoh, Y.; Taki, T.; Arita, N.; Ohnishi, T.; Hayakawa, T. Cell therapy with encapsulated xenogenic tumor cells secreting B-endorphin for treatment of peripheral pain. Cell Transplant. 4:S13-S17; 1995.
    • (1995) Cell Transplant. , vol.4
    • Saitoh, Y.1    Taki, T.2    Arita, N.3    Ohnishi, T.4    Hayakawa, T.5
  • 59
    • 0028858199 scopus 로고
    • Interaction between substance P-immunoreactive central terminals and gamma-aminobutyric acid-immunoreactive elements in synaptic glomeruli in the lamina II of the chicken spinal cord
    • Sakamoto, H.; Atsumi, S. Interaction between substance P-immunoreactive central terminals and gamma-aminobutyric acid-immunoreactive elements in synaptic glomeruli in the lamina II of the chicken spinal cord. Neurosci. Res. 23:335-343; 1995.
    • (1995) Neurosci. Res. , vol.23 , pp. 335-343
    • Sakamoto, H.1    Atsumi, S.2
  • 61
  • 62
    • 0028828510 scopus 로고
    • The adult CNS retains the potential to direct region-specific differentiation of a transplanted neuronal precursor cell line
    • Shihabuddin, L. S.; Hertz, J. A.; Holets, V. R.; Whittemore, S. R. The adult CNS retains the potential to direct region-specific differentiation of a transplanted neuronal precursor cell line. J. Neurosci. 15:6666-6678; 1995.
    • (1995) J. Neurosci. , vol.15 , pp. 6666-6678
    • Shihabuddin, L.S.1    Hertz, J.A.2    Holets, V.R.3    Whittemore, S.R.4
  • 63
    • 0029085649 scopus 로고
    • Descending control of pain
    • Stamford, J. A. Descending control of pain. Br. J. Anaesth. 75:217-227; 1995.
    • (1995) Br. J. Anaesth. , vol.75 , pp. 217-227
    • Stamford, J.A.1
  • 64
    • 0029954479 scopus 로고    scopus 로고
    • Release of gamma-amino-butyric acid in the dorsal horn and suppression of tactile allodynia by spinal cord stimulation in mononeuropathic rats
    • Stiller, C.-O.; Cui, J.-G.; O'Connor, W. T.; Brodin, E.; Meyerson, B. A.; Linderoth, B. Release of gamma-amino-butyric acid in the dorsal horn and suppression of tactile allodynia by spinal cord stimulation in mononeuropathic rats. Neurosurgery 39:367-375; 1996.
    • (1996) Neurosurgery , vol.39 , pp. 367-375
    • Stiller, C.-O.1    Cui, J.-G.2    O'Connor, W.T.3    Brodin, E.4    Meyerson, B.A.5    Linderoth, B.6
  • 65
    • 0001544648 scopus 로고
    • GABA-ergic mechanisms may be involved in the spinal cord stimulation induced reversion of allodynia: Animal studies with microdialysis
    • Stiller, C.-O.; Cui, J. G.; O'Connor, W. T.; Brodin, E.; Meyerson, B. A.; Linderoth, B. GABA-ergic mechanisms may be involved in the spinal cord stimulation induced reversion of allodynia: Animal studies with microdialysis. Am. Pain Soc. Absr. 95801; 1995.
    • (1995) Am. Pain Soc. Absr. 95801
    • Stiller, C.-O.1    Cui, J.G.2    O'Connor, W.T.3    Brodin, E.4    Meyerson, B.A.5    Linderoth, B.6
  • 66
    • 0028803461 scopus 로고
    • Repeated spinal cord stimulation decreases the extracellular level of gamma-aminobutyric acid in the periaqueductal gray matter of freely moving rats
    • Stiller, C. O.; Linderoth, B.; O'Connor, W. T.; Franck, J.; Falkenberg, T.; Ungerstedt, U.; Brodin, E. Repeated spinal cord stimulation decreases the extracellular level of gamma-aminobutyric acid in the periaqueductal gray matter of freely moving rats. Brain Res. 699:231-241; 1995.
    • (1995) Brain Res. , vol.699 , pp. 231-241
    • Stiller, C.O.1    Linderoth, B.2    O'Connor, W.T.3    Franck, J.4    Falkenberg, T.5    Ungerstedt, U.6    Brodin, E.7
  • 67
    • 0021325501 scopus 로고
    • Review: Anticonvulsant drugs and chronic pain
    • Swerdlow, M. Review: Anticonvulsant drugs and chronic pain. Clin. Neuropharmacol. 7:51-84; 1984.
    • (1984) Clin. Neuropharmacol. , vol.7 , pp. 51-84
    • Swerdlow, M.1
  • 70
    • 0022457730 scopus 로고
    • Photochemically induced spinal cord injury in the rat
    • Watson, B. D.; Prado, R.; Dietrich, W. D. Photochemically induced spinal cord injury in the rat. Brain Res. 367: 296-300; 1986.
    • (1986) Brain Res. , vol.367 , pp. 296-300
    • Watson, B.D.1    Prado, R.2    Dietrich, W.D.3
  • 71
    • 0028073280 scopus 로고
    • Distinct regulatory pathways control neurofilament expression and neurotransmitter synthesis in immortalized serotonergic neurons
    • White, L. A.; Eaton, M. J.; Castro, M. C.; Klose, K. J.; Globus, M. Y.; Shaw, G.; Whittemore, S. R. Distinct regulatory pathways control neurofilament expression and neurotransmitter synthesis in immortalized serotonergic neurons. J. Neurosci. 14:6744-6753; 1994.
    • (1994) J. Neurosci. , vol.14 , pp. 6744-6753
    • White, L.A.1    Eaton, M.J.2    Castro, M.C.3    Klose, K.J.4    Globus, M.Y.5    Shaw, G.6    Whittemore, S.R.7
  • 72
    • 0025972301 scopus 로고
    • Transplantation of a temperature-sensitive, nerve growth factor-secreting, neuroblastoma cell line in adult rats with fimbria-fornix lesions rescues cholinergic septal neurons
    • Whittemore, S. R.; Holets, V. R.; Keane, R. W.; Levy, D. J.; McKay, R. D. G. Transplantation of a temperature-sensitive, nerve growth factor-secreting, neuroblastoma cell line in adult rats with fimbria-fornix lesions rescues cholinergic septal neurons. J. Neurosci. Res. 28:156-179; 1991.
    • (1991) J. Neurosci. Res. , vol.28 , pp. 156-179
    • Whittemore, S.R.1    Holets, V.R.2    Keane, R.W.3    Levy, D.J.4    McKay, R.D.G.5
  • 73
    • 0027207697 scopus 로고
    • Target regulation of neuronal differentiation in a temperature-sensitive cell line derived from medullary raphe
    • Whittemore, S. R.; White, L. A. Target regulation of neuronal differentiation in a temperature-sensitive cell line derived from medullary raphe. Brain Res. 615:27-40; 1993.
    • (1993) Brain Res. , vol.615 , pp. 27-40
    • Whittemore, S.R.1    White, L.A.2
  • 75
    • 0027991138 scopus 로고
    • Implantation of AtT-20 or genetically modified AtT-20/hENK cells in mouse spinal cord induced antinociception and opioid tolerance
    • Wu, H. H.; Wilcox, G. L.; McLoon, S. C. Implantation of AtT-20 or genetically modified AtT-20/hENK cells in mouse spinal cord induced antinociception and opioid tolerance. J. Neurosci. 14:4806-4814; 1994.
    • (1994) J. Neurosci. , vol.14 , pp. 4806-4814
    • Wu, H.H.1    Wilcox, G.L.2    McLoon, S.C.3
  • 76
    • 0025277141 scopus 로고
    • Characterization of a cDNA coding for rat glutamic acid decarboxylase
    • Wyborski, R. J.; Bond, R. W.; Gottlieb, D. I. Characterization of a cDNA coding for rat glutamic acid decarboxylase. Mol. Brain Res. 8:193-198; 1990.
    • (1990) Mol. Brain Res. , vol.8 , pp. 193-198
    • Wyborski, R.J.1    Bond, R.W.2    Gottlieb, D.I.3
  • 77
    • 0026501374 scopus 로고
    • Chronic pain-related syndrome in rats after ischemic spinal cord lesion: A possible animal model for pain in patients with spinal cord injury
    • Xu, X.-J.; Hao, J.-X.; Aldoskogius, H.; Seiger, A.; Wiesenfeld-Hallin, Z. Chronic pain-related syndrome in rats after ischemic spinal cord lesion: A possible animal model for pain in patients with spinal cord injury. Pain 48:279-290; 1992.
    • (1992) Pain , vol.48 , pp. 279-290
    • Xu, X.-J.1    Hao, J.-X.2    Aldoskogius, H.3    Seiger, A.4    Wiesenfeld-Hallin, Z.5
  • 78
    • 0024602581 scopus 로고
    • Behavioral and autonomie correlates of the tactile evoked allodynia produced by spinal glycine inhibition: Effects of modulatory receptor systems and excitatory amino acid antagonists
    • Yaksh, T. L. Behavioral and autonomie correlates of the tactile evoked allodynia produced by spinal glycine inhibition: Effects of modulatory receptor systems and excitatory amino acid antagonists. Pain 37:111-123; 1989.
    • (1989) Pain , vol.37 , pp. 111-123
    • Yaksh, T.L.1
  • 80
    • 0023279810 scopus 로고
    • A new double labelling immunofluorescence technique for the determination of proliferation of human astrocytes in culture
    • Yong, V. W.; Kim, S. U. A new double labelling immunofluorescence technique for the determination of proliferation of human astrocytes in culture. J. Neurosci. Methods 21:9-16; 1987.
    • (1987) J. Neurosci. Methods , vol.21 , pp. 9-16
    • Yong, V.W.1    Kim, S.U.2
  • 81
    • 0027931856 scopus 로고
    • Decreased GABA immunoreactivity in spinal cord dorsal horn neurons after transient spinal cord ischemia in the rat
    • Zhang, A.-L.; Hao, J.-X.; Seiger, A.; Xu, X.-J.; Wiesenfeld-Hallin, Z.; Grant, G.; Aldskogius, H. Decreased GABA immunoreactivity in spinal cord dorsal horn neurons after transient spinal cord ischemia in the rat. Brain Res. 656:187-190; 1994.
    • (1994) Brain Res. , vol.656 , pp. 187-190
    • Zhang, A.-L.1    Hao, J.-X.2    Seiger, A.3    Xu, X.-J.4    Wiesenfeld-Hallin, Z.5    Grant, G.6    Aldskogius, H.7
  • 82
    • 0029076687 scopus 로고
    • Effect of intracerebroventricular injection of somatostatin or GABA on pain threshold and contents of GABA or somatostatin in rat brain
    • Zheng, L.; Li, X. C. Effect of intracerebroventricular injection of somatostatin or GABA on pain threshold and contents of GABA or somatostatin in rat brain. Acta Pharmacol. Sinica 16:329-332; 1995.
    • (1995) Acta Pharmacol. Sinica , vol.16 , pp. 329-332
    • Zheng, L.1    Li, X.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.