Effect of modulation of unfolded protein response pathway on dengue virus infection

Acta Biochimica et Biophysica Sinica

Volumn 47, Issue 12, 2015, Pages 960-968

  Diwaker, Drishya ^a   Mishra, Kamla Prasad ^a   Ganju, Lilly ^a  

^a DEFENCE INSTITUTE OF PHYSIOLOGY AND ALLIED SCIENCES   (India)

Author keywords

dengue virus; GRP78; interferon; PKR; UPR

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ATF6 PROTEIN, HUMAN; CYTOKINE; ERN1 PROTEIN, HUMAN; HEAT SHOCK PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MOLECULAR CHAPERONE GRP78; PROTEIN SERINE THREONINE KINASE; PURINE NUCLEOSIDE; RIBONUCLEASE; VER 155008;

ANIMAL; CELL LINE; CHEMISTRY; CYTOLOGY; DENGUE; DENGUE VIRUS; DOSE RESPONSE; ENDOPLASMIC RETICULUM; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INFLAMMATION; INNATE IMMUNITY; INSECT; METABOLISM; MONOCYTE; PROTEIN DENATURATION; UNFOLDED PROTEIN RESPONSE; VIROLOGY;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; CELL LINE; CYTOKINES; DENGUE; DENGUE VIRUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEAT-SHOCK PROTEINS; HUMANS; IMMUNITY, INNATE; INFLAMMATION; INSECTS; MONOCYTES; NF-KAPPA B; PROTEIN DENATURATION; PROTEIN-SERINE-THREONINE KINASES; PURINE NUCLEOSIDES; UNFOLDED PROTEIN RESPONSE;

EID: 84951096003     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gmv108     Document Type: Article

References (36)

1. Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, Drake JM, et al. The global distribution and burden of dengue. Nature 2013, 496: 504-507
2. Halstead SB. Dengue. Lancet 2007, 370: 1644-1652
3. Rigau-Pérez JG, Clark GG, Gubler DJ, Reiter P, Sanders EJ, Vorndam AV. Dengue and dengue haemorrhagic fever. Lancet 1998, 352: 971-977
4. Chambers TJ, Hahn CS, Galler R, Rice CM. Flavivirus genome organization, expression and replication. Annu Rev Microbiol 1990, 44: 649-688
5. Perera R, Kuhn J. Structural proteomics of dengue virus. Curr Opin Microbiol 2008, 11: 369-377
6. Diamond MS, Edgil D, Roberts TG, Lu B, Harris E. Infection of human cells by dengue virus is modulated by different cell types and viral strains. J Virol 2000, 74: 7814-7823
7. Huerre MR, Lan NT, Marianneau P, Hue NB, Khun H, Hung NT, Khen NT, et al. Liver histopathology and biological correlates in five cases of fatal dengue fever in Vietnamese children. Virchows Arch 2001, 438: 107-115
8. Jessie K, Fong MY, Devi S, Lam SK, Wong KT. Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization. J Infect Dis 2004, 189: 1411-1418
9. Basu A, Chaturvedi UC. Vascular endothelium: the battlefield of dengue viruses. FEMS Immunol Med Microbiol 2008, 3: 287-299
10. Halstead SB. Neutralization and antibody-dependent enhancement of dengue viruses. Adv Virus Res 2003, 60: 421-467
11. Smith JA. A new paradigm: innate immune sensing of viruses via the unfolded protein response. Front Microbiol 2014, 5: 222
12. Mori K, Ma W, Gething MJ, Sambrook J. A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 1993, 74: 743-756
13. Cox JS, Shamu CE, Walter P. Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 1993, 73: 1197-1206
14. Harding HP, Zhang Y, Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 1999, 397: 271-274
15. Hendershot LM. The ER function BiP is a master regulator of ER function. Mt Sinai J Med 2004, 71: 289-297
16. Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, Ron D, et al. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 2000, 6: 1099-1108
17. Peña J, Harris E. Dengue virus modulates the unfolded protein response in a time-dependent manner. J Biol Chem 2011, 286: 14226-14236
18. Ye J, Rawson RB, Komuro R, Chen X, Davé UP, Prywes R, Brown MS, et al. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell 2000, 6: 1355-1364
19. Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 2001, 107: 881-891
20. Diwaker D, Mishra KP, Ganju L, Singh SB. Rhodiola inhibits dengue virus multiplication by inducing innate immune response genes RIG-I, MDA5 and ISG in human monocytes. Arch Virol 2014, 159: 1975-1986
21. Mishra KP, Shweta, Diwaker D, Ganju L. Dengue virus infection induces upregulation of hn RNP-H and PDIA3 for its multiplication in the host cell. Virus Res 2012, 163: 573-579
22. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227: 680-685
23. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979, 76: 4350-4354
24. Macias AT, Williamson DS, Allen N, Borgognoni J, Clay A, Daniels Z, Dokurno P, et al. Adenosine-derived inhibitors of 78 kDa glucose regulated protein (Grp78) ATPase: insights into isoform selectivity. J Med Chem 2011, 54: 4034-4041
25. Malhotra JD, Kaufman RJ. The endoplasmic reticulum and the unfolded protein response. Semin Cell Dev Biol 2007, 18: 716-731
26. Lee A-H, Iwakoshi NN, Glimcher LH. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol 2003, 23: 7448-7459
27. Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, Zhao H, Yu X, et al. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004, 21: 81-93
28. Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 2009, 186: 323-331
29. McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 2001, 21: 1249-1259
30. Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004, 11: 381-389
31. Rutkowski DT, Arnold SM, Miller CN, Wu J, Li J, Gunnison KM, Mori K, et al. Adaptation to ER stress is mediated by differential stabilities of prosurvival and pro-apoptotic mRNAs and proteins. PLoS Biol 2006, 4: 2024-2041
32. Hetz CA. ERstress signaling and the BCL-2 family of proteins: fromadaptation to irreversible cellular damage. Antioxid Redox Signal 2007, 9: 2345-2355
33. Kumar A, Haque J, Lacoste J, Hiscott J, Williams BR.Double-strandedRNAdependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B. Proc Natl Acad Sci USA 1994, 91: 6288-6292
34. Cláudio N, Dalet A, Gatti E, Pierre P. Mapping the crossroads of immune activation and cellular stress response pathways. EMBO J 2013, 32: 1214-1224
35. Fraser JE, Watanabe S, Wang C, Chan WKK, Maher B, Lopez-Denman A, Hick C, et al. A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection. J Infect Dis 2014, 210: 1780-1791
36. Rathore APS, Paradkar PN, Watanabe S, Tan KH, Sung C, Connolly JE, Low J, et al. Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model. Antiviral Res 2011, 92: 453-460