Hypoxia impairs anti-viral activity of natural killer (NK) cells but has little effect on anti-fibrotic NK cell functions in hepatitis C virus infection

Journal of Hepatology

Volumn 63, Issue 6, 2015, Pages 1334-1344

  Wolter, Franziska ^b   Glässner, Andreas ^b   Krämer, Benjamin ^b   Kokordelis, Pavlos ^b   Finnemann, Claudia ^b   Kaczmarek, Dominik J ^b   Goeser, Felix ^b   Lutz, Philipp ^b   Nischalke, Hans Dieter ^b   Strassburg, Christian P ^b   Spengler, Ulrich ^b   Nattermann, Jacob ^a  

^a UNIVERSITY OF BONN   (Germany)

^b German Center for Infection Research (DZIF)   (Germany)

Author keywords

HCV; Hepatic stellate cells; HuH7 replicon; Hypoxia; Intrahepatic; Liver infiltrating lymphocytes; NK cells; NKG2D; NKp46

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL KILLER CELL RECEPTOR NKG2D; ANTIVIRUS AGENT; CYTOKINE; KLRK1 PROTEIN, HUMAN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; NCR1 PROTEIN, HUMAN;

ADULT; AGED; ANTIVIRAL ACTIVITY; ARTICLE; CELL HYPOXIA; CHRONIC HEPATITIS C; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE FUNCTION; LYMPHOCYTOPOIESIS; MALE; NATURAL KILLER CELL; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; STELLATE CELL; BIOSYNTHESIS; CASE CONTROL STUDY; CELL LINE; COCULTURE; FIBROSIS; HEPACIVIRUS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; LIVER CELL; METABOLISM; MIDDLE AGED; PATHOGENICITY; VIROLOGY; YOUNG ADULT;

ADULT; AGED; ANTIVIRAL AGENTS; CASE-CONTROL STUDIES; CELL HYPOXIA; CELL LINE; COCULTURE TECHNIQUES; CYTOKINES; FEMALE; FIBROSIS; HEPACIVIRUS; HEPATIC STELLATE CELLS; HEPATITIS C, CHRONIC; HEPATOCYTES; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON-GAMMA; KILLER CELLS, NATURAL; MALE; MIDDLE AGED; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; YOUNG ADULT;

EID: 84951040515     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.08.008     Document Type: Article

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