The aglycone of ginsenoside Rg3 enables glucagon-like peptide-1 secretion in enteroendocrine cells and alleviates hyperglycemia in type 2 diabetic mice

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Kim, Ki Suk ^a   Jung Yang, Hea ^a   Lee, In Seung ^a   Kim, Kang Hoon ^a   Park, Jiyoung ^a   Jeong, Hyeon Soo ^a   Kim, Yoomi ^a,b   Seok Ahn, Kwang ^a   Na, Yun Cheol ^b   Jang, Hyeung Jin ^a  

^a Kyung Hee University   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GINSENOSIDE; GINSENOSIDE RG 3; GLUCAGON LIKE PEPTIDE 1; GUSTDUCIN; TASTE RECEPTORS, TYPE 1; TRANSDUCIN;

ANIMAL; BLOOD; C57BL MOUSE; COMPLICATION; DEFICIENCY; DRUG EFFECTS; ENTEROENDOCRINE CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETICS; GLUCOSE TOLERANCE TEST; HUMAN; HYPERGLYCEMIA; IMMUNOBLOTTING; KNOCKOUT MOUSE; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SECRETION (PROCESS); TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 2; ENTEROENDOCRINE CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GINSENOSIDES; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE TOLERANCE TEST; HUMANS; HYPERGLYCEMIA; IMMUNOBLOTTING; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSDUCIN;

EID: 84950327471     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep18325     Document Type: Article

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