메뉴 건너뛰기




Volumn 83, Issue , 2016, Pages 45-51

Antibiotic transport across bronchial epithelial cells: Effects of molecular weight, LogP and apparent permeability

Author keywords

Antibiotics; Calu 3; LogP; Lung delivery; Molecular weight; Transport

Indexed keywords

AZITHROMYCIN; CIPROFLOXACIN; DOXYCYCLINE; MOXIFLOXACIN; RIFAMPICIN; TOBRAMYCIN; ANTIINFECTIVE AGENT; OCTANOL; WATER;

EID: 84950237874     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2015.12.010     Document Type: Article
Times cited : (17)

References (19)
  • 1
    • 0028948839 scopus 로고
    • A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
    • G.L. Amidon, H. Lennernas, V.P. Shah, and J.R. Crison A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability Pharm. Res. 12 1995 413 420
    • (1995) Pharm. Res. , vol.12 , pp. 413-420
    • Amidon, G.L.1    Lennernas, H.2    Shah, V.P.3    Crison, J.R.4
  • 2
    • 0028810862 scopus 로고
    • The application of cell culture systems in drug discovery and development
    • R. Borchardt The application of cell culture systems in drug discovery and development J. Drug Target. 3 1995 179 182
    • (1995) J. Drug Target. , vol.3 , pp. 179-182
    • Borchardt, R.1
  • 4
    • 77953954921 scopus 로고    scopus 로고
    • Drug transport across pulmonary epithelial cell monolayers: Effects of particle size, apical liquid volume, and deposition technique
    • M. Bur, H. Huwer, L. Muys, and C.M. Lehr Drug transport across pulmonary epithelial cell monolayers: effects of particle size, apical liquid volume, and deposition technique J. Aerosol Med. Pulm. Drug Deliv. 23 2010 119 127
    • (2010) J. Aerosol Med. Pulm. Drug Deliv. , vol.23 , pp. 119-127
    • Bur, M.1    Huwer, H.2    Muys, L.3    Lehr, C.M.4
  • 5
    • 84870386107 scopus 로고    scopus 로고
    • Application of biopharmaceutics classification system (BCS) in drug transport studies across human respiratory epithelial cell monolayers
    • H.-J. Cho, P. Balakrishnan, H. Lin, M.-K. Choi, and D.-D. Kim Application of biopharmaceutics classification system (BCS) in drug transport studies across human respiratory epithelial cell monolayers J. Pharm. Investig. 42 2012 147 153
    • (2012) J. Pharm. Investig. , vol.42 , pp. 147-153
    • Cho, H.-J.1    Balakrishnan, P.2    Lin, H.3    Choi, M.-K.4    Kim, D.-D.5
  • 6
    • 77953459390 scopus 로고    scopus 로고
    • Drug delivery to the lung: Permeability and physicochemical characteristics of drugs as the basis for a pulmonary biopharmaceutical classification system (pBCS)
    • H. Eixarch, E. Haltner-Ukomadu, C. Beisswenger, and U. Bock Drug delivery to the lung: permeability and physicochemical characteristics of drugs as the basis for a pulmonary biopharmaceutical classification system (pBCS) J. Epithelial Biol. Pharmacol. 3 2010 1 14
    • (2010) J. Epithelial Biol. Pharmacol. , vol.3 , pp. 1-14
    • Eixarch, H.1    Haltner-Ukomadu, E.2    Beisswenger, C.3    Bock, U.4
  • 7
    • 0037458930 scopus 로고    scopus 로고
    • Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3
    • B.I. Florea, M.L. Cassara, H.E. Junginger, and G. Borchard Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3 J. Control. Release 87 2003 131 138
    • (2003) J. Control. Release , vol.87 , pp. 131-138
    • Florea, B.I.1    Cassara, M.L.2    Junginger, H.E.3    Borchard, G.4
  • 8
    • 66849142486 scopus 로고    scopus 로고
    • Aerosol antibiotics in cystic fibrosis
    • D.E. Geller Aerosol antibiotics in cystic fibrosis Respir. Care 54 2009 658 670
    • (2009) Respir. Care , vol.54 , pp. 658-670
    • Geller, D.E.1
  • 9
    • 33745630072 scopus 로고    scopus 로고
    • Culture of Calu-3 cells at the air interface provides a representative model of the airway epithelial barrier
    • C. Grainger, L. Greenwell, D. Lockley, G. Martin, and B. Forbes Culture of Calu-3 cells at the air interface provides a representative model of the airway epithelial barrier Pharm. Res. 23 2006 1482 1490
    • (2006) Pharm. Res. , vol.23 , pp. 1482-1490
    • Grainger, C.1    Greenwell, L.2    Lockley, D.3    Martin, G.4    Forbes, B.5
  • 10
    • 77956419131 scopus 로고    scopus 로고
    • Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model
    • M. Haghi, P.M. Young, D. Traini, R. Jaiswal, J. Gong, and M. Bebawy Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model Drug Dev. Ind. Pharm. 36 2010 1207 1214
    • (2010) Drug Dev. Ind. Pharm. , vol.36 , pp. 1207-1214
    • Haghi, M.1    Young, P.M.2    Traini, D.3    Jaiswal, R.4    Gong, J.5    Bebawy, M.6
  • 11
    • 84910036519 scopus 로고    scopus 로고
    • Across the pulmonary epithelial barrier: Integration of physicochemical properties and human cell models to study pulmonary drug formulations
    • M. Haghi, H.X. Ong, D. Traini, and P. Young Across the pulmonary epithelial barrier: integration of physicochemical properties and human cell models to study pulmonary drug formulations Pharmacol. Ther. 144 2014 235 252
    • (2014) Pharmacol. Ther. , vol.144 , pp. 235-252
    • Haghi, M.1    Ong, H.X.2    Traini, D.3    Young, P.4
  • 12
    • 24944523222 scopus 로고    scopus 로고
    • Evidence of efflux-mediated and saturable absorption of rifampicin in rat intestine using the ligated loop and everted gut sac techniques
    • T.T. Mariappan, and S. Singh Evidence of efflux-mediated and saturable absorption of rifampicin in rat intestine using the ligated loop and everted gut sac techniques Mol. Pharm. 1 2004 363 367
    • (2004) Mol. Pharm. , vol.1 , pp. 363-367
    • Mariappan, T.T.1    Singh, S.2
  • 13
    • 0036125277 scopus 로고    scopus 로고
    • Permeability characteristics of Calu-3 human bronchial epithelial cells: In vitro-in vivo correlation to predict lung absorption in rats
    • N.R. Mathia, J. Timoszyk, P.I. Stetsko, J.R. Megill, R.L. Smith, and D.A. Wall Permeability characteristics of Calu-3 human bronchial epithelial cells: in vitro-in vivo correlation to predict lung absorption in rats J. Drug Target. 10 2002 31 40
    • (2002) J. Drug Target. , vol.10 , pp. 31-40
    • Mathia, N.R.1    Timoszyk, J.2    Stetsko, P.I.3    Megill, J.R.4    Smith, R.L.5    Wall, D.A.6
  • 14
    • 0035313918 scopus 로고    scopus 로고
    • Methods used to assess pulmonary deposition and absorption of drugs
    • C. Mobley, and G. Hochhaus Methods used to assess pulmonary deposition and absorption of drugs Drug Discov. Today 6 2001 367 375
    • (2001) Drug Discov. Today , vol.6 , pp. 367-375
    • Mobley, C.1    Hochhaus, G.2
  • 15
    • 84877842865 scopus 로고    scopus 로고
    • Ciprofloxacin is actively transported across bronchial lung epithelial cells using a Calu-3 air interface cell model
    • H.X. Ong, D. Traini, M. Bebawy, and P.M. Young Ciprofloxacin is actively transported across bronchial lung epithelial cells using a Calu-3 air interface cell model Antimicrob. Agents Chemother. 57 2013 2535 2540
    • (2013) Antimicrob. Agents Chemother. , vol.57 , pp. 2535-2540
    • Ong, H.X.1    Traini, D.2    Bebawy, M.3    Young, P.M.4
  • 16
    • 0038725719 scopus 로고    scopus 로고
    • Experimental estimation of the role of P-glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model
    • J.I. Pachot, R.P. Botham, K.D. Haegele, and K. Hwang Experimental estimation of the role of P-glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model J. Pharm. Pharm. Sci. 6 2003 1 12
    • (2003) J. Pharm. Pharm. Sci. , vol.6 , pp. 1-12
    • Pachot, J.I.1    Botham, R.P.2    Haegele, K.D.3    Hwang, K.4
  • 17
    • 84876182606 scopus 로고    scopus 로고
    • Quercetin solid lipid microparticles: A flavonoid for inhalation lung delivery
    • S. Scalia, M. Haghi, V. Losi, V. Trotta, P.M. Young, and D. Traini Quercetin solid lipid microparticles: a flavonoid for inhalation lung delivery Eur. J. Pharm. Sci. 49 2013 278 285
    • (2013) Eur. J. Pharm. Sci. , vol.49 , pp. 278-285
    • Scalia, S.1    Haghi, M.2    Losi, V.3    Trotta, V.4    Young, P.M.5    Traini, D.6
  • 18
    • 45049083552 scopus 로고    scopus 로고
    • Formulation of rifampicin-cyclodextrin complexes for lung nebulization
    • F. Tewes, J. Brillault, W. Couet, and J.C. Olivier Formulation of rifampicin-cyclodextrin complexes for lung nebulization J. Control. Release 129 2008 93 99
    • (2008) J. Control. Release , vol.129 , pp. 93-99
    • Tewes, F.1    Brillault, J.2    Couet, W.3    Olivier, J.C.4
  • 19
    • 70249104706 scopus 로고    scopus 로고
    • Delivery of antibiotics to the respiratory tract: An update
    • D. Traini, and P.M. Young Delivery of antibiotics to the respiratory tract: an update Expert Opin. Drug Deliv. 6 2009 897 905
    • (2009) Expert Opin. Drug Deliv. , vol.6 , pp. 897-905
    • Traini, D.1    Young, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.