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Volumn 112, Issue 50, 2015, Pages E6917-E6926

Temporal fate mapping reveals age-linked heterogeneity in naive T lymphocytes in mice

Author keywords

Ki67; Kinetic heterogeneity; Mathematical modeling; T cell homeostasis

Indexed keywords

BUSULFAN;

EID: 84950106752     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1517246112     Document Type: Article
Times cited : (42)

References (40)
  • 1
    • 0035902576 scopus 로고    scopus 로고
    • How alpha beta T cells deal with induced TCR alpha ablation
    • Polic B, Kunkel D, Scheffold A, Rajewsky K (2001) How alpha beta T cells deal with induced TCR alpha ablation. Proc Natl Acad Sci USA 98(15):8744-8749.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.15 , pp. 8744-8749
    • Polic, B.1    Kunkel, D.2    Scheffold, A.3    Rajewsky, K.4
  • 2
    • 0034677036 scopus 로고    scopus 로고
    • Tetracycline-controllable selection of CD4(+) T cells: Half-life and survival signals in the absence of major histocompatibility complex class II molecules
    • Witherden D, et al. (2000) Tetracycline-controllable selection of CD4(+) T cells: Half-life and survival signals in the absence of major histocompatibility complex class II molecules. J Exp Med 191(2):355-364.
    • (2000) J Exp Med , vol.191 , Issue.2 , pp. 355-364
    • Witherden, D.1
  • 3
    • 0034907484 scopus 로고    scopus 로고
    • How much TCR does a T cell need?
    • Labrecque N, et al. (2001) How much TCR does a T cell need? Immunity 15(1):71-82.
    • (2001) Immunity , vol.15 , Issue.1 , pp. 71-82
    • Labrecque, N.1
  • 4
    • 0036786514 scopus 로고    scopus 로고
    • TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells
    • Seddon B, Zamoyska R (2002) TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells. J Immunol 169(7):3752-3759.
    • (2002) J Immunol , vol.169 , Issue.7 , pp. 3752-3759
    • Seddon, B.1    Zamoyska, R.2
  • 5
    • 0038665233 scopus 로고    scopus 로고
    • IL-15 promotes the survival of naive and memory phenotype CD8+ T cells
    • Berard M, Brandt K, Bulfone-Paus S, Tough DF (2003) IL-15 promotes the survival of naive and memory phenotype CD8+ T cells. J Immunol 170(10):5018-5026.
    • (2003) J Immunol , vol.170 , Issue.10 , pp. 5018-5026
    • Berard, M.1    Brandt, K.2    Bulfone-Paus, S.3    Tough, D.F.4
  • 6
    • 4143085811 scopus 로고    scopus 로고
    • Suppression of IL7Ralpha transcription by IL-7 and other pro-survival cytokines: A novel mechanism for maximizing IL-7-dependent T cell survival
    • Park JH, et al. (2004) Suppression of IL7Ralpha transcription by IL-7 and other pro-survival cytokines: A novel mechanism for maximizing IL-7-dependent T cell survival. Immunity 21(2):289-302.
    • (2004) Immunity , vol.21 , Issue.2 , pp. 289-302
    • Park, J.H.1
  • 7
    • 18944379196 scopus 로고    scopus 로고
    • The many faces of IL-7: From lymphopoiesis to peripheral T cell maintenance
    • Fry TJ, Mackall CL (2005) The many faces of IL-7: From lymphopoiesis to peripheral T cell maintenance. J Immunol 174(11):6571-6576.
    • (2005) J Immunol , vol.174 , Issue.11 , pp. 6571-6576
    • Fry, T.J.1    Mackall, C.L.2
  • 8
    • 0033180494 scopus 로고    scopus 로고
    • Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts
    • Goldrath AW, Bevan MJ (1999) Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts. Immunity 11(2):183-190.
    • (1999) Immunity , vol.11 , Issue.2 , pp. 183-190
    • Goldrath, A.W.1    Bevan, M.J.2
  • 9
    • 0037105615 scopus 로고    scopus 로고
    • TCR signals mediated by Src family kinases are essential for the survival of naive T cells
    • Seddon B, Zamoyska R (2002) TCR signals mediated by Src family kinases are essential for the survival of naive T cells. J Immunol 169(6):2997-3005.
    • (2002) J Immunol , vol.169 , Issue.6 , pp. 2997-3005
    • Seddon, B.1    Zamoyska, R.2
  • 10
    • 0343527207 scopus 로고    scopus 로고
    • Quantification of cell turnover kinetics using 5-bromo-2′-deoxyuridine
    • Bonhoeffer S, Mohri H, Ho D, Perelson AS (2000) Quantification of cell turnover kinetics using 5-bromo-2′-deoxyuridine. J Immunol 164(10):5049-5054.
    • (2000) J Immunol , vol.164 , Issue.10 , pp. 5049-5054
    • Bonhoeffer, S.1    Mohri, H.2    Ho, D.3    Perelson, A.S.4
  • 12
    • 0037461298 scopus 로고    scopus 로고
    • Estimating average cellular turnover from 5-bromo-2′-deoxyuridine (BrdU) measurements
    • De Boer RJ, Mohri H, Ho DD, Perelson AS (2003) Estimating average cellular turnover from 5-bromo-2′-deoxyuridine (BrdU) measurements. Proc Biol Sci 270(1517):849-858.
    • (2003) Proc Biol Sci , vol.270 , Issue.1517 , pp. 849-858
    • De Boer, R.J.1    Mohri, H.2    Ho, D.D.3    Perelson, A.S.4
  • 13
    • 0042476384 scopus 로고    scopus 로고
    • Measurement and modeling of human T cell kinetics
    • Macallan DC, et al. (2003) Measurement and modeling of human T cell kinetics. Eur J Immunol 33(8):2316-2326.
    • (2003) Eur J Immunol , vol.33 , Issue.8 , pp. 2316-2326
    • Macallan, D.C.1
  • 14
    • 33947225091 scopus 로고    scopus 로고
    • Quantification of T-cell dynamics: From telomeres to DNA labeling
    • Borghans JAM, de Boer RJ (2007) Quantification of T-cell dynamics: From telomeres to DNA labeling. Immunol Rev 216:35-47.
    • (2007) Immunol Rev , vol.216 , pp. 35-47
    • Jam, B.1    De Boer, R.J.2
  • 15
    • 77649194239 scopus 로고    scopus 로고
    • Explicit kinetic heterogeneity: Mathematical models for interpretation of deuterium labeling of heterogeneous cell populations
    • Ganusov VV, Borghans JAM, De Boer RJ (2010) Explicit kinetic heterogeneity: Mathematical models for interpretation of deuterium labeling of heterogeneous cell populations. PLOS Comput Biol 6(2):e1000666.
    • (2010) PLOS Comput Biol , vol.6 , Issue.2 , pp. e1000666
    • Ganusov, V.V.1    Jam, B.2    De Boer, R.J.3
  • 16
    • 84864598576 scopus 로고    scopus 로고
    • Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity
    • De Boer RJ, Perelson AS, Ribeiro RM (2012) Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity. J R Soc Interface 9(74): 2191-2200.
    • (2012) J R Soc Interface , vol.9 , Issue.74 , pp. 2191-2200
    • De Boer, R.J.1    Perelson, A.S.2    Ribeiro, R.M.3
  • 17
    • 84871286707 scopus 로고    scopus 로고
    • A mechanistic model for bromodeoxyuridine dilution naturally explains labelling data of self-renewing T cell populations
    • Ganusov VV, De Boer RJ (2013) A mechanistic model for bromodeoxyuridine dilution naturally explains labelling data of self-renewing T cell populations. J R Soc Interface 10(78):20120617.
    • (2013) J R Soc Interface , vol.10 , Issue.78 , pp. 20120617
    • Ganusov, V.V.1    De Boer, R.J.2
  • 18
    • 84876093634 scopus 로고    scopus 로고
    • Quantifying T lymphocyte turnover
    • De Boer RJ, Perelson AS (2013) Quantifying T lymphocyte turnover. J Theor Biol 327: 45-87.
    • (2013) J Theor Biol , vol.327 , pp. 45-87
    • De Boer, R.J.1    Perelson, A.S.2
  • 19
    • 84904225676 scopus 로고    scopus 로고
    • A new model to simulate and analyze proliferating cell populations in BrdU labeling experiments
    • Schittler D, Allgöwer F, De Boer RJ (2013) A new model to simulate and analyze proliferating cell populations in BrdU labeling experiments. BMC Syst Biol 7(Suppl 1): S4.
    • (2013) BMC Syst Biol 7(Suppl 1) , vol.4
    • Schittler, D.1    Allgöwer, F.2    De Boer, R.J.3
  • 20
    • 84887335296 scopus 로고    scopus 로고
    • Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans
    • Westera L, et al. (2013) Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans. Blood 122(13):2205-2212.
    • (2013) Blood , vol.122 , Issue.13 , pp. 2205-2212
    • Westera, L.1
  • 21
    • 0035169609 scopus 로고    scopus 로고
    • Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy
    • Mohri H, et al. (2001) Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy. J Exp Med 194(9):1277-1287.
    • (2001) J Exp Med , vol.194 , Issue.9 , pp. 1277-1287
    • Mohri, H.1
  • 22
    • 43149105163 scopus 로고    scopus 로고
    • Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool
    • Vrisekoop N, et al. (2008) Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool. Proc Natl Acad Sci USA 105(16):6115-6120.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.16 , pp. 6115-6120
    • Vrisekoop, N.1
  • 23
    • 0034307331 scopus 로고    scopus 로고
    • Comparison of different busulfan analogues for depletion of hematopoietic stem cells and promotion of donor-type chimerism in murine bone marrow transplant recipients
    • Westerhof GR, et al. (2000) Comparison of different busulfan analogues for depletion of hematopoietic stem cells and promotion of donor-type chimerism in murine bone marrow transplant recipients. Cancer Res 60(19):5470-5478.
    • (2000) Cancer Res , vol.60 , Issue.19 , pp. 5470-5478
    • Westerhof, G.R.1
  • 24
    • 0037804775 scopus 로고    scopus 로고
    • Nonmyeloablative conditioning is sufficient to allow en-graftment of EGFP-expressing bone marrow and subsequent acceptance of EGFP-transgenic skin grafts in mice
    • Andersson G, et al. (2003) Nonmyeloablative conditioning is sufficient to allow en-graftment of EGFP-expressing bone marrow and subsequent acceptance of EGFP-transgenic skin grafts in mice. Blood 101(11):4305-4312.
    • (2003) Blood , vol.101 , Issue.11 , pp. 4305-4312
    • Andersson, G.1
  • 25
    • 34548143353 scopus 로고    scopus 로고
    • Low-dose parenteral busulfan provides an extended window for the infusion of hematopoietic stem cells in murine hosts
    • Hsieh MM, et al. (2007) Low-dose parenteral busulfan provides an extended window for the infusion of hematopoietic stem cells in murine hosts. Exp Hematol 35(9): 1415-1420.
    • (2007) Exp Hematol , vol.35 , Issue.9 , pp. 1415-1420
    • Hsieh, M.M.1
  • 26
    • 21644446773 scopus 로고    scopus 로고
    • Fatal radiation myelopathy after high-dose busulfan and melphalan chemotherapy and radiotherapy for Ewing's sarcoma: A review of the literature and implications for practice
    • Seddon BM, Cassoni AM, Galloway MJ, Rees JH, Whelan JS (2005) Fatal radiation myelopathy after high-dose busulfan and melphalan chemotherapy and radiotherapy for Ewing's sarcoma: A review of the literature and implications for practice. Clin Oncol (R Coll Radiol) 17(5):385-390.
    • (2005) Clin Oncol (R Coll Radiol) , vol.17 , Issue.5 , pp. 385-390
    • Seddon, B.M.1    Cassoni, A.M.2    Galloway, M.J.3    Rees, J.H.4    Whelan, J.S.5
  • 27
    • 0036198778 scopus 로고    scopus 로고
    • T cell receptor excision circle assessment of thymopoiesis in aging mice
    • Sempowski GD, Gooding ME, Liao HX, Le PT, Haynes BF (2002) T cell receptor excision circle assessment of thymopoiesis in aging mice. Mol Immunol 38(11):841-848.
    • (2002) Mol Immunol , vol.38 , Issue.11 , pp. 841-848
    • Sempowski, G.D.1    Gooding, M.E.2    Liao, H.X.3    Le, P.T.4    Haynes, B.F.5
  • 28
    • 1142269467 scopus 로고    scopus 로고
    • Age-related thymic involution in C57BL/6J x DBA/2J recombinant-inbred mice maps to mouse chromosomes 9 and 10
    • Hsu HC, et al. (2003) Age-related thymic involution in C57BL/6J x DBA/2J recombinant-inbred mice maps to mouse chromosomes 9 and 10. Genes Immun 4(6):402-410.
    • (2003) Genes Immun , vol.4 , Issue.6 , pp. 402-410
    • Hsu, H.C.1
  • 29
    • 84871835297 scopus 로고    scopus 로고
    • Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age
    • Johnson PLF, Yates AJ, Goronzy JJ, Antia R (2012) Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age. Proc Natl Acad Sci USA 109(52):21432-21437.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.52 , pp. 21432-21437
    • Plf, J.1    Yates, A.J.2    Goronzy, J.J.3    Antia, R.4
  • 30
    • 0036135578 scopus 로고    scopus 로고
    • Development and homeostasis of T cell memory in rhesus macaque
    • Pitcher CJ, et al. (2002) Development and homeostasis of T cell memory in rhesus macaque. J Immunol 168(1):29-43.
    • (2002) J Immunol , vol.168 , Issue.1 , pp. 29-43
    • Pitcher, C.J.1
  • 31
    • 84857416171 scopus 로고    scopus 로고
    • Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans
    • den Braber I, et al. (2012) Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans. Immunity 36(2):288-297.
    • (2012) Immunity , vol.36 , Issue.2 , pp. 288-297
    • Den Braber, I.1
  • 32
    • 47249143671 scopus 로고    scopus 로고
    • Kinetics of in vivo proliferation and death of memory and naive CD8 T cells: Parameter estimation based on 5-bromo-2′-deoxyuridine incorporation in spleen, lymph nodes, and bone marrow
    • Parretta E, et al. (2008) Kinetics of in vivo proliferation and death of memory and naive CD8 T cells: Parameter estimation based on 5-bromo-2′-deoxyuridine incorporation in spleen, lymph nodes, and bone marrow. J Immunol 180(11):7230-7239.
    • (2008) J Immunol , vol.180 , Issue.11 , pp. 7230-7239
    • Parretta, E.1
  • 33
    • 0032101049 scopus 로고    scopus 로고
    • The role of the thymus and recent thymic migrants in the maintenance of the adult peripheral lymphocyte pool
    • Berzins SP, Boyd RL, Miller JF (1998) The role of the thymus and recent thymic migrants in the maintenance of the adult peripheral lymphocyte pool. J Exp Med 187(11):1839-1848.
    • (1998) J Exp Med , vol.187 , Issue.11 , pp. 1839-1848
    • Berzins, S.P.1    Boyd, R.L.2    Miller, J.F.3
  • 35
    • 84874539245 scopus 로고    scopus 로고
    • Heterogeneity in thymic emigrants: Implications for thymectomy and immunosenescence
    • Bains I, Yates AJ, Callard RE (2013) Heterogeneity in thymic emigrants: Implications for thymectomy and immunosenescence. PLoS One 8(2):e49554.
    • (2013) PLoS One , vol.8 , Issue.2 , pp. e49554
    • Bains, I.1    Yates, A.J.2    Callard, R.E.3
  • 36
    • 40749115606 scopus 로고    scopus 로고
    • Mathematical modeling reveals the biological program regulating lymphopenia-induced proliferation
    • Yates A, Saini M, Mathiot A, Seddon B (2008) Mathematical modeling reveals the biological program regulating lymphopenia-induced proliferation. J Immunol 180(3): 1414-1422.
    • (2008) J Immunol , vol.180 , Issue.3 , pp. 1414-1422
    • Yates, A.1    Saini, M.2    Mathiot, A.3    Seddon, B.4
  • 37
    • 84867019241 scopus 로고    scopus 로고
    • Measurement of red cell lifespan and aging
    • Franco RS (2012) Measurement of red cell lifespan and aging. Transfus Med Hemother 39(5):302-307.
    • (2012) Transfus Med Hemother , vol.39 , Issue.5 , pp. 302-307
    • Franco, R.S.1
  • 38
    • 84895552474 scopus 로고    scopus 로고
    • Theories and quantification of thymic selection
    • Yates AJ (2014) Theories and quantification of thymic selection. Front Immunol 5:13.
    • (2014) Front Immunol , vol.5 , pp. 13
    • Yates, A.J.1
  • 39
    • 0037243278 scopus 로고    scopus 로고
    • Neonates support lymphopenia-induced proliferation
    • Min B, et al. (2003) Neonates support lymphopenia-induced proliferation. Immunity 18(1):131-140.
    • (2003) Immunity , vol.18 , Issue.1 , pp. 131-140
    • Min, B.1
  • 40
    • 82255181234 scopus 로고    scopus 로고
    • IL-7 determines the homeostatic fitness of T cells by distinct mechanisms at different signalling thresholds in vivo
    • Pearson C, Silva A, Saini M, Seddon B
    • Pearson C, Silva A, Saini M, Seddon B (2011) IL-7 determines the homeostatic fitness of T cells by distinct mechanisms at different signalling thresholds in vivo. Eur J Immunol 41(12):3656-3666.
    • (2011) Eur J Immunol , vol.41 , Issue.12 , pp. 3656-3666


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