Synthesis and characterization of a novel pH-thermo dual responsive hydrogel based on salecan and poly(N,N-diethylacrylamide-co-methacrylic acid)

Colloids and Surfaces B: Biointerfaces

Volumn 136, Issue , 2015, Pages 1182-1192

  Wei, Wei ^a   Qi, Xiaoliang ^a   Liu, Yucheng ^a   Li, Junjian ^a   Hu, Xinyu ^a   Zuo, Gancheng ^a   Zhang, Jianfa ^a   Dong, Wei ^a  

^a NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Doxorubicin; Drug delivery; Poly(N,N Diethylacrylamide); Salecan; Semi IPN hydrogels

Indexed keywords

ACRYLIC MONOMERS; BIOMATERIALS; DRUG DELIVERY; FOURIER TRANSFORM INFRARED SPECTROSCOPY; INTERPENETRATING POLYMER NETWORKS; POLYMERS; PORE SIZE; SCANNING ELECTRON MICROSCOPY; SOIL TESTING; THERMOGRAVIMETRIC ANALYSIS; X RAY DIFFRACTION;

DOXORUBICIN; POLY (N ISOPROPYLACRYLAMIDE); POLY(N , N-DIETHYLACRYLAMIDE); SALECAN; SEMI-INTERPENETRATING POLYMER NETWORK HYDROGEL; SEMI-IPN HYDROGELS; SEMIINTERPENETRATING POLYMER NETWORKS (SEMI-IPNS); SYNTHESIS AND CHARACTERIZATIONS;

HYDROGELS;

DOXORUBICIN; POLY(N,N DIETHYLACRYLAMIDE CO METHACRYLIC ACID); POLYMER; POLYSACCHARIDE; SALECAN; UNCLASSIFIED DRUG; ACRYLAMIDE DERIVATIVE; BETA GLUCAN; HYDROGEL; METHACRYLIC ACID DERIVATIVE; POLY(N,N-DIETHYLACRYLAMIDE);

A549 CELL LINE; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG CYTOTOXICITY; FLUORESCENCE MICROSCOPY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HYDROGEL; INFRARED SPECTROSCOPY; PARTICLE SIZE; PH; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TEMPERATURE DEPENDENCE; THERMOGRAVIMETRY; THERMOSTABILITY; X RAY DIFFRACTION; CHEMISTRY; FLOW KINETICS;

ACRYLAMIDES; BETA-GLUCANS; HYDROGELS; HYDROGEN-ION CONCENTRATION; METHACRYLATES; POLYMERS; RHEOLOGY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMOGRAVIMETRY; X-RAY DIFFRACTION;

EID: 84949953320     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2015.11.007     Document Type: Article

References (55)

1. Zhou H.Y., Jiang L.J., Cao P.P., Li J.B., Chen X.G. Glycerophosphate-based chitosan thermosensitive hydrogels and their biomedical applications. Carbohydr. Polym. 2015, 117:524-536.
2. Wang B., Xu X.D., Wang Z.C., Cheng S.X., Zhang X.Z., Zhuo R.X. Synthesis and properties of pH and temperature sensitive P(NIPAAm-co-DMAEMA) hydrogels. Colloids Surf. B Biointerfaces 2008, 64:34-41.
3. Chen R., Chen Q., Huo D., Ding Y., Hu Y., Jiang X. In situ formation of chitosan-gold hybrid hydrogel and its application for drug delivery. Colloids Surf. B Biointerfaces 2012, 97:132-137.
4. Gil E., Hudson S. Stimuli-reponsive polymers and their bioconjugates. Prog. Polym. Sci. 2004, 29:1173-1222.
5. Pahimanolis N., Sorvari A., Luong N.D., Seppala J. Thermoresponsive xylan hydrogels via copper-catalyzed azide-alkyne cycloaddition. Carbohydr. Polym. 2014, 102:637-644.
6. Cevik O., Gidon D., Kizilel S. Visible-light-induced synthesis of pH-responsive composite hydrogels for controlled delivery of the anticonvulsant drug pregabalin. Acta Biomater. 2015, 11:151-161.
7. Pérez E., Fernández A., Olmo R., Teijón J.M., Blanco M.D. pH and glutathion-responsive hydrogel for localized delivery of paclitaxel. Colloids Surf. B Biointerfaces 2014, 116:247-256.
8. Gao S., Wu C., Jiang H., Chen D., Li Q., Liu X., Wang X. Size-controlled porous superparamagnetic Zn1/3Fe8/3O4 nanospheres: synthesis, properties and application for drug delivery. RSC Adv. 2014, 4:20841-20846.
9. Wang Y., Nie J., Chang B., Sun Y., Yang W. Poly(vinylcaprolactam)-based biodegradable multiresponsive microgels for drug delivery. Biomacromolecules 2013, 14:3034-3046.
10. Gui R., Wang Y., Sun J. Embedding fluorescent mesoporous silica nanoparticles into biocompatible nanogels for tumor cell imaging and thermo/pH-sensitive in vitro drug release. Colloids Surf. B Biointerfaces 2014, 116:518-525.
11. Zhou T., Zhou X., Xing D. Controlled release of doxorubicin from graphene oxide based charge-reversal nanocarrier. Biomaterials 2014, 35:4185-4194.
12. Dragan E.S., Apopei D.F. Multiresponsive macroporous semi-IPN composite hydrogels based on native or anionically modified potato starch. Carbohydr. Polym. 2013, 92:23-32.
13. Spoljaric S., Salminen A., Luong N.D., Seppälä J. Stable, self-healing hydrogels from nanofibrillated cellulose, poly(vinyl alcohol) and borax via reversible crosslinking. Eur. Polym. J. 2014, 56:105-117.
14. Zhou M., Pu C., Xia L., Yu X., Zhu B., Cheng R., Xu L., Zhang J. Salecan diet increases short chain fatty acids and enriches beneficial microbiota in the mouse cecum. Carbohydr. Polym. 2014, 102:772-779.
15. Zhou M., Jia P., Chen J., Xiu A., Zhao Y., Zhan Y., Chen P., Zhang J. Laxative effects of salecan on normal and two models of experimental constipated mice. BMC Gastroenterol. 2013, 13:52-57.
16. Chen P., Wang Z., Zeng L., Wang S., Dong W., Jia A., Cai C., Zhang J. Protective effects of salecan against carbon tetrachloride-induced acute liver injury in mice. J. Appl. Toxicol. 2012, 32:796-803.
17. Xiu A., Zhou M., Zhu B., Wang S., Zhang J. Rheological properties of salecan as a new source of thickening agent. Food Hydrocolloids 2011, 25:1719-1725.
18. Wei W., Hu X., Qi X., Yu H., Liu Y., Li J., Zhang J., Dong W. A novel thermo-responsive hydrogel based on salecan and poly(N-isopropylacrylamide): synthesis and characterization. Colloids Surf. B Biointerfaces 2015, 125:1-11.
19. Hu X.Y., Feng L.D., Xie A.M., Wei W., Wang S.M., Zhang J.F., Dong W. Synthesis and characterization of a novel hydrogel: salecan/polyacrylamide semi-IPN hydrogel with a desirable pore structure. J. Mater. Chem. B 2014, 2:3646-3658.
20. Hu X., Feng L., Wei W., Xie A., Wang S., Zhang J., Dong W. Synthesis and characterization of a novel semi-IPN hydrogel based on Salecan and poly(N,N-dimethylacrylamide-co-2-hydroxyethyl methacrylate). Carbohydr. Polym. 2014, 105:135-144.
21. Dragan E.S. Design and applications of interpenetrating polymer network hydrogels. A review. Chem. Eng. J. 2014, 243:572-590.
22. Ngadaonye J.I., Geever L.M., Killion J., Higginbotham C.L. Development of novel chitosan-poly(N,N-diethylacrylamide) IPN films for potential wound dressing and biomedical applications. J. Polym. Res. 2013, 20.
23. Liu B., Wang J., Ru G., Liu C., Feng J. Phase transition and preferential alcohol adsorption of poly(N,N-diethylacrylamide) gel in water/alcohol mixtures. Macromolecules 2015, 48:1126-1133.
24. Tajima H., Yoshida Y., Yamagiwa K. Experimental study of swelling and shrinking kinetics of spherical poly(N,N-diethylacrylamide) gel with continuous phase transition. Polymer 2011, 52:732-738.
25. Hiratani H., Alvarez-Lorenzo C. Timolol uptake and release by imprinted soft contact lenses made of N,N-diethylacrylamide and methacrylic acid. J. Control. Release 2002, 83:223-230.
26. Ngadaonye J.I., Geever L.M., Cloonan M.O., Higginbotham C.L. Photopolymerised thermo-responsive poly(N,N-diethylacrylamide)-based copolymer hydrogels for potential drug delivery applications. J. Polym. Res. 2012, 19.
27. Pleštil J., Ilavský M., Pospíšil H., Hlavatá D., Ostanevich Y.M., Degovics G., Kriechbaum M., Laggner P. SAXS, SANS and photoelasticity of poly(N,N-diethylacrylamide) networks: 1. Structure changes after temperature jumps. Polymer 1993, 34:4846-4851.
28. Spěváček J., Geschke D., Ilavský M. 1H NMR study of temperature collapse of linear and crosslinked poly(N,N-diethylacrylamide) in D2O. Polymer 2001, 42:463-468.
29. Cuggino J.C., Contreras C.B., Jimenez-Kairuz A., Maletto B.A., Alvarez Igarzabal C.I. Novel poly(NIPA-co-AAc) functional hydrogels with potential application in drug controlled release. Mol. pharm. 2014, 11:2239-2249.
30. Zhang Z., Chen L., Zhao C., Bai Y., Deng M., Shan H., Zhuang X., Chen X., Jing X. Thermo- and pH-responsive HPC-g-AA/AA hydrogels for controlled drug delivery applications. Polymer 2011, 52:676-682.
31. Chen X., Chen S., Wang J. A pH-responsive poly(N-isopropylacrylamide-co-acrylic acid) hydrogel for the selective isolation of hemoglobin from human blood. Analyst 2010, 135:1736-1741.
32. Liu H., Liu M., Ma L., Chen J. Thermo- and pH-sensitive comb-type grafted poly(N,N-diethylacrylamide-co-acrylic acid) hydrogels with rapid response behaviors. Eur. Polym. J. 2009, 45:2060-2067.
33. Hu X., Wei W., Qi X., Yu H., Feng L., Li J., Wang S., Zhang J., Dong W. Preparation and characterization of a novel pH-sensitive salecan-g-poly(acrylic acid) hydrogel for controlled release of doxorubicin. J. Mater. Chem. B 2015, 3:2685-2697.
34. Sarmad S., Yenici G., Gürkan K., Keçeli G., Gürdağ G. Electric field responsive chitosan-poly(N,N-dimethyl acrylamide) semi-IPN gel films and their dielectric, thermal and swelling characterization. Smart Mater. Struct. 2013, 22:055010.
35. Lee J.W., Kim S.Y., Kim S.S., Lee Y.M., Lee K.H., Kim S.J. Synthesis and characteristics of interpenetrating polymer network hydrogel composed of chitosan and poly(acrylic acid). J. Appl. Polym. Sci. 1999, 73:113-120.
36. Liu D., Liu H., Hu N. pH-, sugar-, and temperature-sensitive electrochemical switch amplified by enzymatic reaction and controlled by logic gates based on semi-interpenetrating polymer networks. J. Phys. Chem. B 2012, 116:1700-1708.
37. Qi X., Hu X., Wei W., Yu H., Li J., Zhang J., Dong W. Investigation of salecan/poly(vinyl alcohol) hydrogels prepared by freeze/thaw method. Carbohydr. Polym. 2015, 118:60-69.
38. Wang J., Zhou X., Xiao H. Structure and properties of cellulose/poly(N-isopropylacrylamide) hydrogels prepared by SIPN strategy. Carbohydr. Polym. 2013, 94:749-754.
39. Sathaye S., Mbi A., Sonmez C., Chen Y., Blair D.L., Schneider J.P., Pochan D.J. Rheology of peptide- and protein-based physical hydrogels: are everyday measurements just scratching the surface? Wiley interdisciplinary reviews. Nanomed. Nanobiotechnol. 2015, 7:34-68.
40. Liu Y., Chan-Park M.B. Hydrogel based on interpenetrating polymer networks of dextran and gelatin for vascular tissue engineering. Biomaterials 2009, 30:196-207.
41. Wang S., Oommen O.P., Yan H., Varghese O.P. Mild and efficient strategy for site-selective aldehyde modification of glycosaminoglycans: tailoring hydrogels with tunable release of growth factor. Biomacromolecules 2013, 14:2427-2432.
42. Kayaman-Apohan N., Baysal B.M. Semi-interpenetrating hydrogel networks of poly(2-hydroxyethyl methacrylate) with poly[(d,l-lactic acid)-co-(e-caprolactam)]. Macromol. Chem. Phys. 2001, 202:1182-1188.
43. Sun J., Xiao C., Tan H., Hu X. Covalently crosslinked hyaluronic acid-chitosan hydrogel containing dexamethasone as an injectable scaffold for soft tissue engineering. J. Appl. Polym. Sci. 2012.
44. 2-chitosan scaffolds for photocatalytic applications. J. Mater. Chem. 2009, 19:8478.
45. Panayiotoua M., Freitag R. Synthesis and characterisation of stimuli-responsive poly(N,N'-diethylacrylamide) hydrogels. Polymer 2005, 46:615-621.
46. Jacchetti E., Emilitri E., Rodighiero S., Indrieri M., Gianfelice A., Lenardi C., Podestà A., Ranucci E., Ferruti P., Milani P. Biomimetic poly(amidoamine) hydrogels as synthetic materials for cell culture. J. Nanobiotechnol. 2008, 6:14.
47. Gao X., Cao Y., Song X., Zhang Z., Xiao C., He C., Chen X. pH- and thermo-responsive poly(N-isopropylacrylamide-co-acrylic acid derivative) copolymers and hydrogels with LCST dependent on pH and alkyl side groups. J. Mater. Chem. B 2013, 1:5578-5587.
48. Xu Q., Huang W., Jiang L., Lei Z., Li X., Deng H. KGM and PMAA based pH-sensitive interpenetrating polymer network hydrogel for controlled drug release. Carbohydr. Polym. 2013, 97:565-570.
49. Pourjavadi A., Harzandi A.M., Hosseinzadeh H. Modified carrageenan. 6. Crosslinked graft copolymer of methacrylic acid and kappa-carrageenan as a novel superabsorbent hydrogel with low salt- and high pH-sensitivity. Macromol. Res. 2005, 13:483-490.
50. Cirillo G., Spataro T., Curcio M., Spizzirri U.G., Nicoletta F.P., Picci N., Iemma F. Tunable thermo-responsive hydrogels: synthesis, structural analysis and drug release studies. Mater. Sci. Eng. C Mater. Biol. Appl. 2015, 48:499-510.
51. Hu Y., Darcos V., Monge S., Li S., Zhou Y., Su F. Thermo-responsive release of curcumin from micelles prepared by self-assembly of amphiphilic P(NIPAAm-co-DMAAm)-b-PLLA-b-P(NIPAAm-co-DMAAm) triblock copolymers. Int. J. Pharm. 2014, 476:31-40.
52. Chen C.Y., Wang H.L. Dual thermo- and pH-responsive zwitterionic sulfobataine copolymers for oral delivery system. Macromol. Rapid Commun. 2014, 35:1534-1540.
53. Huh H.W., Zhao L., Kim S.Y. Biomineralized biomimetic organic/inorganic hybrid hydrogels based on hyaluronic acid and poloxamer. Carbohydr. Polym. 2015, 126:130-140.
54. Sivakumaran D., Maitland D., Hoare T. Injectable microgel-hydrogel composites for prolonged small-molecule drug delivery. Biomacromolecules 2011, 12:4112-4120.
55. Chen S., Liu M., Jin S., Chen Y. pH-/temperature-sensitive carboxymethyl chitosan/poly(N-isopropylacrylamide-co-methacrylic acid) IPN: preparation, characterization and sustained release of riboflavin. Polym. Bull. (Heidelberg, Ger.) 2014, 71:719-734.