Targeting of primary breast cancers and metastases in a transgenic mouse model using rationally designed multifunctional SPIONs

ACS Nano

Volumn 6, Issue 3, 2012, Pages 2591-2601

  Kievit, Forrest M ^a   Stephen, Zachary R ^a   Veiseh, Omid ^a   Arami, Hamed ^a   Wang, Tingzhong ^b   Lai, Vy P ^c   Park, James O ^c   Ellenbogen, Richard G ^c   Disis, Mary L ^c   Zhang, Miqin ^a,c  

^a University of Washington   (United States)

^b CHINA MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

breast cancer; genetically engineered mouse model; HER2 neu; iron oxide; metastases; nanoparticle; theranostics

Indexed keywords

BREAST CANCER; HER2/NEU; METASTASES; MOUSE MODELS; THERANOSTICS;

DISEASES; GENETIC ENGINEERING; IRON OXIDES; MAGNETIC RESONANCE; MAMMALS; MONOCLONAL ANTIBODIES; PATHOLOGY; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; SUPERPARAMAGNETISM; TUMORS; ZETA POTENTIAL;

MEDICAL IMAGING;

CHITOSAN; DIAGNOSTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MACROGOL DERIVATIVE; MAGNETITE NANOPARTICLE; MONOCLONAL ANTIBODY;

ANIMAL; ARTICLE; BREAST TUMOR; CHEMISTRY; DISEASE MODEL; DRUG DESIGN; ENZYME SPECIFICITY; IMMUNOLOGY; METABOLISM; METASTASIS; MOUSE; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHYSICAL CHEMISTRY; TRANSGENIC MOUSE; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; BREAST NEOPLASMS; CELL LINE, TUMOR; CHITOSAN; DISEASE MODELS, ANIMAL; DRUG DESIGN; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MICE; MICE, TRANSGENIC; NEOPLASM METASTASIS; PHYSICOCHEMICAL PROCESSES; POLYETHYLENE GLYCOLS; RECEPTOR, ERBB-2; SUBSTRATE SPECIFICITY;

EID: 84859118459     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn205070h     Document Type: Article

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