Cryo-EM structures of the E. Coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ

eLife

Volumn 4, Issue OCTOBER2015, 2015, Pages

  Fernandez Leiro, Rafael ^a   Conrad, Julian ^a   Scheres, Sjors H W ^a   Lamers, Meindert H ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE ETA; DNA SLIDING CLAMP BETA; EXONUCLEASE; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; DNA BINDING; DNA REPLICATION; ELECTRO MOBILITY SHIFT ASSAY; ENZYME ACTIVITY; ENZYME STRUCTURE; ESCHERICHIA COLI; GEL FILTRATION CHROMATOGRAPHY; IMAGE PROCESSING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REPLISOME;

EID: 84949908505     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.11134     Document Type: Article

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